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Items: 1 to 100 of 2866

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
BRCA1
Single nucleotide variant
(3 prime UTR variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
BRCA1
Single nucleotide variant
(3 prime UTR variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GBenign/Likely benign
BRCA1
Single nucleotide variant
(3 prime UTR variant +1 more)
Hereditary cancer-predisposing syndrome
GLikely benign
BRCA1
Single nucleotide variant
(3 prime UTR variant)
Breast-ovarian cancer, familial, susceptibility to, 1
+1 more
GLikely benign
BRCA1
Deletion
(3 prime UTR variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
BRCA1
Single nucleotide variant
(3 prime UTR variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GConflicting classifications of pathogenicity
BRCA1
Single nucleotide variant
(3 prime UTR variant +1 more)
Hereditary cancer-predisposing syndrome
GUncertain significance
BRCA1
Single nucleotide variant
(3 prime UTR variant +1 more)
Hereditary cancer-predisposing syndrome
GUncertain significance
BRCA1
Single nucleotide variant
(3 prime UTR variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GConflicting classifications of pathogenicity
BRCA1
Single nucleotide variant
(3 prime UTR variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GLikely benign
BRCA1
Single nucleotide variant
(synonymous variant +2 more)
Hereditary cancer-predisposing syndrome
GLikely benign
BRCA1
Single nucleotide variant
(stop lost +1 more)
Hereditary cancer-predisposing syndrome
GUncertain significance
BRCA1
(Y1863C +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
BRCA1
(Y1863D +80 more)
Single nucleotide variant
(missense variant +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
+3 more
GUncertain significance
BRCA1
(H1733Q +80 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
GUncertain significance
BRCA1
Single nucleotide variant
(synonymous variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GLikely benign
BRCA1
(H1862L +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary breast ovarian cancer syndrome
+4 more
GBenign/Likely benign
BRCA1
Deletion
(inframe_indel +3 more)
not specified
+4 more
GConflicting classifications of pathogenicity
BRCA1
(H756fs +3 more)
Duplication
(frameshift variant +2 more)
not provided
+4 more
GConflicting classifications of pathogenicity
BRCA1
(P1859R +80 more)
Single nucleotide variant
(missense variant +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GBenign
BRCA1
Single nucleotide variant
(synonymous variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GLikely benign
BRCA1
(I1858T +80 more)
Single nucleotide variant
(missense variant +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
+3 more
GConflicting classifications of pathogenicity
BRCA1
(I1858L +80 more)
Single nucleotide variant
(missense variant +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GBenign
BRCA1
(Q1857H +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary breast ovarian cancer syndrome
+3 more
GUncertain significance
BRCA1
(P1856L +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
GUncertain significance
BRCA1
(P1856T +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
+1 more
GConflicting classifications of pathogenicity
BRCA1
(P1856S +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary breast ovarian cancer syndrome
+3 more
GLikely benign
BRCA1
Single nucleotide variant
(synonymous variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GLikely benign
BRCA1
(Y1853* +3 more)
Duplication
(frameshift variant +3 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(Y1853C +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary breast ovarian cancer syndrome
+2 more
GPathogenic/Likely pathogenic
BRCA1
Single nucleotide variant
(synonymous variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GLikely benign
BRCA1
(T1852I +80 more)
Single nucleotide variant
(missense variant +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
+3 more
GConflicting classifications of pathogenicity
BRCA1
Single nucleotide variant
(synonymous variant +1 more)
Hereditary breast ovarian cancer syndrome
+1 more
GLikely benign
BRCA1
Single nucleotide variant
(synonymous variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GLikely benign
BRCA1
Single nucleotide variant
(synonymous variant +1 more)
Hereditary cancer-predisposing syndrome
+2 more
GLikely benign
BRCA1
(Q1846H +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
+2 more
GConflicting classifications of pathogenicity
BRCA1
Single nucleotide variant
(synonymous variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GLikely benign
BRCA1
Single nucleotide variant
(synonymous variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GLikely benign
BRCA1
(L1844P +80 more)
Single nucleotide variant
(missense variant +2 more)
not provided
+2 more
GConflicting classifications of pathogenicity
BRCA1
(L1844R +80 more)
Single nucleotide variant
(missense variant +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GBenign
BRCA1
(L1865I +80 more)
Indel
(missense variant +2 more)
Hereditary breast ovarian cancer syndrome
+2 more
GConflicting classifications of pathogenicity
BRCA1
Single nucleotide variant
(synonymous variant +1 more)
Hereditary cancer-predisposing syndrome
GLikely benign
BRCA1
(V1795A +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
GUncertain significance
BRCA1
Single nucleotide variant
(synonymous variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GLikely benign
BRCA1
(S1841T +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary breast ovarian cancer syndrome
+2 more
GConflicting classifications of pathogenicity
BRCA1
(S1841N +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary breast ovarian cancer syndrome
+2 more
GConflicting classifications of pathogenicity
BRCA1
Single nucleotide variant
(synonymous variant +1 more)
Hereditary cancer-predisposing syndrome
GLikely benign
BRCA1
(D1840fs +3 more)
Deletion
(frameshift variant +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(L1839S +80 more)
Single nucleotide variant
(missense variant +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
Single nucleotide variant
(synonymous variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GLikely benign
BRCA1
(V1838E +80 more)
Single nucleotide variant
(missense variant +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(V1838L +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary breast ovarian cancer syndrome
+1 more
GUncertain significance
BRCA1
(V1838M +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary breast ovarian cancer syndrome
+2 more
GConflicting classifications of pathogenicity
BRCA1
(W1837C +80 more)
Single nucleotide variant
(missense variant +2 more)
not provided
+2 more
GPathogenic
BRCA1
(W1837C +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
+1 more
GPathogenic/Likely pathogenic
BRCA1
(W1837R +80 more)
Single nucleotide variant
(missense variant +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(E1836K +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary breast ovarian cancer syndrome
+4 more
GUncertain significance
BRCA1
(V1786fs +3 more)
Indel
(frameshift variant +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(R1835P +80 more)
Single nucleotide variant
(missense variant +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
+4 more
GUncertain significance
BRCA1
(R1835Q +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary breast ovarian cancer syndrome
+5 more
GConflicting classifications of pathogenicity
BRCA1
(R1835* +80 more)
Single nucleotide variant
(nonsense +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(T1834I +80 more)
Single nucleotide variant
(missense variant +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
+4 more
GConflicting classifications of pathogenicity
BRCA1
(V1833M +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary breast ovarian cancer syndrome
+4 more
GPathogenic/Likely pathogenic
BRCA1
(V1785M +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary breast ovarian cancer syndrome
+1 more
GUncertain significance
BRCA1
(P1831R +80 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
+4 more
GConflicting classifications of pathogenicity
BRCA1
(E1829K +80 more)
Single nucleotide variant
(missense variant +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
+4 more
GUncertain significance
BRCA1
(M1827I +90 more)
Single nucleotide variant
(missense variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
+4 more
GConflicting classifications of pathogenicity
BRCA1
(M1848K +90 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
GUncertain significance
BRCA1
(D698N +9 more)
Single nucleotide variant
(synonymous variant +1 more)
Hereditary cancer-predisposing syndrome
GLikely benign
BRCA1
Deletion
(splice acceptor variant)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(A697V +90 more)
Single nucleotide variant
(nonsense +2 more)
Hereditary breast ovarian cancer syndrome
+1 more
GPathogenic
BRCA1
(Q1826K +90 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GConflicting classifications of pathogenicity
BRCA1
(I1824V +90 more)
Single nucleotide variant
(missense variant +1 more)
not provided
+6 more
GConflicting classifications of pathogenicity
BRCA1
Single nucleotide variant
(splice acceptor variant)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
Single nucleotide variant
(intron variant)
Hereditary breast ovarian cancer syndrome
+1 more
GConflicting classifications of pathogenicity
BRCA1
Single nucleotide variant
(intron variant)
Hereditary cancer-predisposing syndrome
GLikely benign
BRCA1
Single nucleotide variant
(intron variant)
Hereditary cancer-predisposing syndrome
GUncertain significance
BRCA1
Microsatellite
(intron variant)
Hereditary breast ovarian cancer syndrome
+3 more
GBenign/Likely benign
BRCA1
Single nucleotide variant
(intron variant)
Breast-ovarian cancer, familial, susceptibility to, 1
GBenign
BRCA1
Single nucleotide variant
(intron variant)
Hereditary breast ovarian cancer syndrome
+1 more
GConflicting classifications of pathogenicity
BRCA1
Single nucleotide variant
(intron variant)
Hereditary breast ovarian cancer syndrome
+2 more
GConflicting classifications of pathogenicity
BRCA1
Deletion
(splice donor variant)
Hereditary cancer-predisposing syndrome
GPathogenic/Likely pathogenic
BRCA1
Single nucleotide variant
(intron variant)
Hereditary cancer-predisposing syndrome
GLikely benign
BRCA1
Single nucleotide variant
(intron variant)
Hereditary breast ovarian cancer syndrome
+1 more
GLikely benign
BRCA1
Single nucleotide variant
(intron variant)
not specified
+2 more
GLikely benign
BRCA1
Single nucleotide variant
(intron variant)
Hereditary cancer-predisposing syndrome
GLikely benign
BRCA1
Single nucleotide variant
(intron variant)
Hereditary breast ovarian cancer syndrome
+3 more
GConflicting classifications of pathogenicity
BRCA1
Single nucleotide variant
(splice donor variant)
Hereditary cancer-predisposing syndrome
+3 more
GPathogenic/Likely pathogenic
BRCA1
(C694R +9 more)
Single nucleotide variant
(synonymous variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GLikely benign
BRCA1
(H1775fs +4 more)
Insertion
(frameshift variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(G1820S +90 more)
Single nucleotide variant
(missense variant +2 more)
Familial cancer of breast
+3 more
GConflicting classifications of pathogenicity
BRCA1
(N1819S +80 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary breast ovarian cancer syndrome
+2 more
GBenign/Likely benign
BRCA1
(Q690* +9 more)
Single nucleotide variant
(synonymous variant +1 more)
Hereditary cancer-predisposing syndrome
+1 more
GConflicting classifications of pathogenicity
BRCA1
(D1818G +80 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+3 more
GPathogenic/Likely pathogenic
BRCA1
(T1816K +90 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
GUncertain significance
BRCA1
(W1815* +90 more)
Single nucleotide variant
(nonsense +2 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(W1815S +80 more)
Single nucleotide variant
(missense variant +1 more)
Hereditary cancer-predisposing syndrome
+3 more
GUncertain significance
BRCA1
(W1815* +80 more)
Single nucleotide variant
(nonsense +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GPathogenic
BRCA1
(A1767D +90 more)
Single nucleotide variant
(missense variant +2 more)
Hereditary cancer-predisposing syndrome
+1 more
GUncertain significance
BRCA1
(C685R +9 more)
Single nucleotide variant
(synonymous variant +1 more)
Breast-ovarian cancer, familial, susceptibility to, 1
GLikely benign
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