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Items: 25

Variation
Gene
(Protein Change)
Type
(Consequence)
ConditionClassification, Review status
KAT6B
(G1140fs +7 more)
Deletion
(frameshift variant)
Blepharophimosis - intellectual disability syndrome, SBBYS type
GPathogenic
WARS1
(R119* +1 more)
Single nucleotide variant
(nonsense)
not specified
GUncertain significance
IRAK1BP1, PHIP
(Q1263E)
Single nucleotide variant
(missense variant)
not provided
GUncertain significance
CHD3
(R1725W +2 more)
Single nucleotide variant
(missense variant)
Snijders Blok-Campeau syndrome
GConflicting classifications of pathogenicity
WDR26
(P226L +2 more)
Single nucleotide variant
(missense variant)
not provided
GLikely pathogenic
CTCF
(R368C +1 more)
Single nucleotide variant
(missense variant)
Intellectual disability-feeding difficulties-developmental delay-microcephaly syndrome
+1 more
GPathogenic
CHD8
(R1242Q +1 more)
Single nucleotide variant
(missense variant)
Intellectual developmental disorder with autism and macrocephaly
GLikely pathogenic
WAC
(R2* +1 more)
Single nucleotide variant
(nonsense)
DeSanto-Shinawi syndrome due to WAC point mutation
+1 more
GPathogenic
AUTS2
(Q326*)
Single nucleotide variant
(nonsense)
Inborn genetic diseases
GPathogenic
TRIO
(K1431M)
Single nucleotide variant
(missense variant +1 more)
TRIO-related disorder
+1 more
GPathogenic
SPEN
(R1265*)
Single nucleotide variant
(nonsense)
Inborn genetic diseases
+1 more
GPathogenic
ADNP
(S955fs)
Deletion
(frameshift variant)
ADNP-related multiple congenital anomalies - intellectual disability - autism spectrum disorder
+2 more
GPathogenic/Likely pathogenic
SCN2A
(L611fs)
Microsatellite
(frameshift variant)
Seizures, benign familial infantile, 3
+4 more
GPathogenic
SMARCA2
(R505Q)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+1 more
GPathogenic/Likely pathogenic
GNAO1
Single nucleotide variant
(splice donor variant)
Inborn genetic diseases
+1 more
GPathogenic
PACS2
(E209K +1 more)
Single nucleotide variant
(missense variant)
Developmental and epileptic encephalopathy, 1
+5 more
GPathogenic/Likely pathogenic
UBTF, ATXN7L3-AS1
(E210K)
Single nucleotide variant
(missense variant +1 more)
See cases
+6 more
GPathogenic/Likely pathogenic
RYR2
(I4857V)
Single nucleotide variant
(missense variant)
Catecholaminergic polymorphic ventricular tachycardia 1
+1 more
GConflicting classifications of pathogenicity
CHD2
(R1637*)
Single nucleotide variant
(nonsense)
not provided
+4 more
GPathogenic
ZMYND11
(R600W +15 more)
Single nucleotide variant
(missense variant +1 more)
Intellectual disability, autosomal dominant 30
+4 more
GPathogenic/Likely pathogenic
GRIN2B
(G820A)
Single nucleotide variant
(missense variant)
Inborn genetic diseases
+3 more
GPathogenic/Likely pathogenic
MEA1, PPP2R5D
(E198K +3 more)
Single nucleotide variant
(missense variant)
Intellectual disability
+6 more
GPathogenic
PTEN
Single nucleotide variant
(splice acceptor variant)
not provided
+2 more
GPathogenic
DYRK1A
(R437* +2 more)
Single nucleotide variant
(nonsense)
Inborn genetic diseases
+2 more
GPathogenic
GATAD2B
(Q470*)
Single nucleotide variant
(nonsense)
Inborn genetic diseases
GPathogenic
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