3PJR


Conserved Protein Domain Family
pcrA

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TIGR01073: pcrA 
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ATP-dependent DNA helicase PcrA
Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair]
Statistics
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PSSM-Id: 273429
Aligned: 8 rows
Threshold Bit Score: 1089.03
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3PJR_A         8 LLAHLNKEQQEAVRTTEGPLLIMAGAGSGKTRVLTHRIAYLMAEKHVAPWNILAITFTNKAAREMRERVQSLLGG----- 82  Geobacillus ste...
O34580         8 LLSGLNPVQQEAVKTTDGPLLLMAGAGSGKTRVLTHRIAYLMAEKHVAPWNILAITFTNKAAREMKERVESILGP----- 82  Bacillus subtil...
P56255         8 LLAHLNKEQQEAVRTTEGPLLIMAGAGSGKTRVLTHRIAYLMAEKHVAPWNILAITFTNKAAREMRERVQSLLGG----- 82  Geobacillus ste...
Q53727         4 LLNHMNTEQSEAVKTTEGPLLIMAGAGSGKTRVLTHRIAYLLDEKDVSPYNVLAITFTNKAAREMKERVQKLVGD----- 78  Staphylococcus ...
Q9S3Q0         6 LTNGMNNKQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAHLVQDLNVFPWRILAITFTNKAAREMRERIAALLSEd---- 81  Leuconostoc cit...
Q9ZD95        10 FMHTLNAEQKKAALHTEGPLLLLAGAGTGKTKVLTSRIANIIHQNLALPHNILAVTFTNKAAKEMSERVHNLIN------ 83  Rickettsia prow...
WP_010872135   9 yLAHLNPSQRRAVEHFCGPLLVVAGAGSGKTRALTYRIAHLIRQHRINPENILAVTFTNKAAKEMKERLEKIFAQawaqq 88  Synechocystis s...
CAB92660      69 LLEGLNENQRAAVVHSGSPLLIVAGAGSGKTRVLTHRIAHLLAERNVHPGQILAITFTNKAAGEMKERVEQLVGP----- 143 Streptomyces co...
3PJR_A        83 ------------------------AAEDVWISTFHSMCVRILRRDID----RIG--INRNFSILDPTDQLSVMKTILK-E 131 Geobacillus ste...
O34580        83 ------------------------GADDIWISTFHSMCVRILRRDID----RIG--INRNFSILDTADQLSVIKGILK-E 131 Bacillus subtil...
P56255        83 ------------------------AAEDVWISTFHSMCVRILRRDID----RIG--INRNFSILDPTDQLSVMKTILK-E 131 Geobacillus ste...
Q53727        79 ------------------------QAEVIWMSTFHSMCVRILRRDAD----RIG--IERNFTIIDPTDQKSVIKDVLK-N 127 Staphylococcus ...
Q9S3Q0        82 ------------------------VARDIWVSTFHALAVRILRRDGE----AIG--LAKNFTIIDTSAQRTLMKRVIN-D 130 Leuconostoc cit...
Q9ZD95        84 -------------------------CYGLNIGTFHSMAAKILRDQIEn--lNLG--FNNRFTIISHDDQLTLVKDIVKlK 134 Rickettsia prow...
WP_010872135  89 efsqrwellgkyeqkqllsrvyktVTKPLWIGTFHSLCSRILRYDIDkyqdSSGrrWTKQFSIFDESDVQSLFKTIVTkD 168 Synechocystis s...
CAB92660     144 ------------------------RANAMWVMTFHSACVRILRRESK----KLG--FTSSFSIYDAADSKRLMALVCR-D 192 Streptomyces co...
3PJR_A       132 KNIDPKKFEPRTILGTISAAKNELLPPEQFAKRASTY-YEKVVSDVYQEYQQRLLRNHSLDFDDLIMTTIQLFDRVPDVL 210 Geobacillus ste...
O34580       132 RNLDPKKFDPRSILGTISSAKNELTEPEEFSKVAGGY-YDQVVSDVYADYQKKLLKNQSLDFDDLIMTTIKLFDRVPEVL 210 Bacillus subtil...
P56255       132 KNIDPKKFEPRTILGTISAAKNELLPPEQFAKRASTY-YEKVVSDVYQEYQQRLLRNHSLDFDDLIMTTIQLFDRVPDVL 210 Geobacillus ste...
Q53727       128 ENIDSKKFEPRMFIGAISNLKNELKTPADAQKEATDY-HSQMVATVYSGYQRQLSRNEALDFDDLIMTTINLFERVPEVL 206 Staphylococcus ...
Q9S3Q0       131 LNLDTNQYDPRTILGMISNAKNDMLQPRDYAKAADNA-FQETVAEVYTAYQAELKRSQSVDFDDLIMLTIDLFQSAPDVL 209 Leuconostoc cit...
Q9ZD95       135 KDIDAKKYTPKLIHIIISRWKDQGLLPNKLSTSDTNLpLQKIAKLVYEEYQKNLLISNVLDFGDLLLYNNELFIKNPAVL 214 Rickettsia prow...
WP_010872135 169 MDLDEKQFNPKSIRYQVSNAKNLGQSPETYLRENPSY-KGRVIAEVYQAYQNQLAANNALDFDDLILIPTRLFQQNESVL 247 Synechocystis s...
CAB92660     193 LDLDPKRFPPKSFSAKISNLKNELIDEEDFAAQAADG-FEKTLAQAYAMYQSRLREANALDFDDLIMTTVNLLRAFPDVA 271 Streptomyces co...
3PJR_A       211 HYYQYKFQYIHIDEYQDTNRAQYTLVKKLAER---------------FQNICAVGDADQSIYRWRGADIQNILSFERDYP 275 Geobacillus ste...
O34580       211 EFYQRKFQYIHVDEYQDTNRAQYMLVKQLAER---------------FQNLCVVGDSDQSIYRWRGADITNILSFEKDYP 275 Bacillus subtil...
P56255       211 HYYQYKFQYIHIDEYQDTNRAQYTLVKKLAER---------------FQNICAVGDADQSIYRWRGADIQNILSFERDYP 275 Geobacillus ste...
Q53727       207 EYYQNKFQYIHVDEYQDTNKAQYTLVKLLASK---------------FKNLCVVGDSDQSIYGWRGADIQNILSFEKDYP 271 Staphylococcus ...
Q9S3Q0       210 ARYQQQFEYLHVDEYQDTNDAQYTIVNLLAQR---------------SKNLAVVGDADQSIYGWRGANMNNILNFEKDYP 274 Leuconostoc cit...
Q9ZD95       215 KYYQEKYRYILIDEYQDTNIAQYLWARMLASL---------------YRNICCVGDDDQSIYGWRGAEVGNILRFEKDFA 279 Rickettsia prow...
WP_010872135 248 GYWHRKFNHILVDEYQDTNRIQYDLIRLLSTNgeerqs----ewdwrGRSTFVVGDADQSIYSFRMADFTILLNFQEDFG 323 Synechocystis s...
CAB92660     272 EHYRRRFRHVLVDEYQDTNHAQYALVRELVGVpsehpvdvppeaevpPAELCVVGDADQSIYAFRGATIRNILQFEEDYP 351 Streptomyces co...
3PJR_A       276 N-------AKVILLEQNYRSTKRILQAANEVIEHNVNRKPKRIWTENPEGKPILYYEAMNEADEAQFVAGRIREAVERG- 347 Geobacillus ste...
O34580       276 N-------ASVILLEQNYRSTKRILRAANEVIKNNSNRKPKNLWTENDEGIKISYYRGDNEFGEGQFVAGKIHQLHSTG- 347 Bacillus subtil...
P56255       276 N-------AKVILLEQNYRSTKRILQAANEVIEHNVNRKPKRIWTENPEGKPILYYEAMNEADEAQFVAGRIREAVERG- 347 Geobacillus ste...
Q53727       272 E-------ANTIFLEQNYRSTKTILNAANEVIKNNSERKPKGLWTANTNGEKIHYYEAMTERDEAEFVIREIMKHQRNG- 343 Staphylococcus ...
Q9S3Q0       275 N-------AHTVMLEQNYRSTQNILDAANAVINHNNERVPKKLWTENGKGDQITYYRAQTEHDEANFILSNIQQLRETK- 346 Leuconostoc cit...
Q9ZD95       280 G-------ATIIKLEQNYRSTLPILAAASNVINNNKNRHSKTLWTDSSSGEKIKIISCLSDKEEARYIACEIDKLVKEE- 351 Rickettsia prow...
WP_010872135 324 DrlldgetTTMVKLEENYRSRENILQAANHLIEHNSQRIDKILKATRSGGDDIILYQADDERDESRFVINKILSLRKNNp 403 Synechocystis s...
CAB92660     352 D-------ATTILLEQNYRSTQTILSAANAVIERNESRRPKNLWTNQGSGAQITGYVADTEHDEAQFVADEIDRLTDAG- 423 Streptomyces co...
3PJR_A       348 ERRYRDFAVLYRTNAQSRVMEEMLLKANIPYQIVGGLKFYDRKEIKDILAYLRVIANPDDDLSLLRIINVPKRGIGASTI 427 Geobacillus ste...
O34580       348 KRKLSDIAILYRTNAQSRVIEETLLKAGLNYNIVGGTKFYDRKEIKDILAYLRLVSNPDDDISFTRIVNVPKRGVGATSL 427 Bacillus subtil...
P56255       348 ERRYRDFAVLYRTNAQSRVMEEMLLKANIPYQIVGGLKFYDRKEIKDILAYLRVIANPDDDLSLLRIINVPKRGIGASTI 427 Geobacillus ste...
Q53727       344 K-KYQDMAILYRTNAQSRVLEETFMKSNMPYTMVGGQKFYDRKEIKDLLSYLRIIANSNDDISLQRIINVPKRGVGPSSV 422 Staphylococcus ...
Q9S3Q0       347 HMAYSDFAVLYRTNAQSRNIEESLVKANMPYSMVGGHKFYERKEILDIMAYMSLITNPDDNAAFERVVNEPKRGLGATSL 426 Leuconostoc cit...
Q9ZD95       352 RYNAGNIAILVRAGFQTRSFEEAFINSAIPYKIIGGLRFYERMEIRDVLAYIRISLNQNDNLALERIINVPKRAIGAASL 431 Rickettsia prow...
WP_010872135 404 ELNFGDFAILYRTNAQSRAFEEQLLNNNIRYNIVGGFRFYDRQEIKDAIAYLRVLVNPADTVSLLRIINTPRRGIGKSTI 483 Synechocystis s...
CAB92660     424 EAKAGDVAVFYRTNAQSRVFEEVFIRTGLPYKVVGGVRFYERKEVRDVLAYLRVLANPEDSVPLRRILNVPKRGIGDRAE 503 Streptomyces co...
3PJR_A       428 DKLVRYAADHELSLFEALGELEMIg-LGAKAAGALAAFRSQLEQWTQLQE-YVSVTELVEEVLDKSGYREMLKAERTIEA 505 Geobacillus ste...
O34580       428 EKIASYAAINGLSFFQAIQQVDFIg-VSAKAANALDSFRQMIENLTNMQD-YLSITELTEEILDKTEYREMLKAEKSIEA 505 Bacillus subtil...
P56255       428 DKLVRYAADHELSLFEALGELEMIg-LGAKAAGALAAFRSQLEQWTQLQE-YVSVTELVEEVLDKSGYREMLKAERTIEA 505 Geobacillus ste...
Q53727       423 EKVQNYALQNNISMFDALGEADFIg-LSKKVTQECLNFYELIQSLIKEQE-FLEIHEIVDEVLQKSGYREMLERENTLES 500 Staphylococcus ...
Q9S3Q0       427 TRLRELANRLNVSYMKAIGSIELApsITTKAASKFLTFAEMMHNLRQQSE-FLNVTELTELVMTQSGYRQMLAEKNDPDS 505 Leuconostoc cit...
Q9ZD95       432 NKIRSYALERNISNFAAIKEILEIgnIKAKSYESLKDLLTKIDNWYEQFI-IDTPINVVKAILDDSGYLAMLKEEKTEEA 510 Rickettsia prow...
WP_010872135 484 EGFVNASKELDIPLWEIITDETSVntLAGRSGKKTLQFARMLQEIQSQIG-ELSASEALSLVLEKSNYVDDLKQKGTEEA 562 Synechocystis s...
CAB92660     504 AMIDALSQREKISFPQALRRVDEAygMAARSANAVKRFNTLMEDLRTIVEsGAGPATVLEAILERTGYLAELQASTDPQD 583 Streptomyces co...
3PJR_A       506 QSRLENLDEFLSVTKHFENVS---DD----KSLIAFLTDLALISDLDELDGTEqaaE---G-DAVMLMTLHAAKGLEFPV 574 Geobacillus ste...
O34580       506 QSRLENIDEFLSVTKNFEQKS---ED----KTLVAFLTDLALIADIDQLDQKE---EesgGkDAITLMTLHAAKGLEFPV 575 Bacillus subtil...
P56255       506 QSRLENLDEFLSVTKHFENVS---DD----KSLIAFLTDLALISDLDELDGTE---QaaeG-DAVMLMTLHAAKGLEFPV 574 Geobacillus ste...
Q53727       501 RSRLENIDEFMSVPKDYEENTp-lEE----QSLINFLTDLSLVADIDEADT-----En--G---VTLMTMHSAKGLEFPI 565 Staphylococcus ...
Q9S3Q0       506 QARLENLEEFLSVTKEFDDKYq-pEDpesiDPVTDFLGTTALMSDLDDFEE---------GdGAVTLMTLHAAKGLEFPV 575 Leuconostoc cit...
Q9ZD95       511 FGRIENINEMLRAIAEFNDIH-------------DFIEYSSLVMENEVLETNy-------G-GSVTIMTLHAAKGLEFDV 569 Rickettsia prow...
WP_010872135 563 DNRLANLGELDNAVRQFEAES---ED----PSLVDFLASASLTSDLDDLEES--------G-DEVSLMTLHSAKGLEFPV 626 Synechocystis s...
CAB92660     584 ETRIENLQELAAVALEFEQERaegEEa---GTLADFLEKVALVADSDQIPDEE---D---GdGVVTLMTLHTAKGLEFPV 654 Streptomyces co...
3PJR_A       575 VFLIGMEEGIFPHNRSLE--DDDEMEEERRLAYVGITRAEEELVLTSAQMRTLFGNIQMDPPSRFLNEIPAHLLETASR- 651 Geobacillus ste...
O34580       576 VFLMGLEEGVFPHSRSLM--EEAEMEEERRLAYVGITRAEQELYLTNAKMRTLFGRTNMNPESRFIAEIPDDLLENLNEk 653 Bacillus subtil...
P56255       575 VFLIGMEEGIFPHNRSLE--DDDEMEEERRLAYVGITRAEEELVLTSAQMRTLFGNIQMDPPSRFLNEIPAHLLETASR- 651 Geobacillus ste...
Q53727       566 VFIMGMEESLFPHIRAIKseDDHEMQEERRICYVAITRAEEVLYITHATSRMLFGRPQSNMPSRFLKEIPESLLENHSS- 644 Staphylococcus ...
Q9S3Q0       576 VFLIGLKEGIFPLSRAMM--DEDLLEEERRLAYVGITRAMKKLFLTNAFSRLLYGRTQANEPSRFIAEISPELLETAYSg 653 Leuconostoc cit...
Q9ZD95       570 VFLPGWEEGVFPSQRSLDedGEKGLEEERRIAYVGITRAKKDLYITHAESRKIFYEIVRSCPSRFINEIPDEItirtssm 649 Rickettsia prow...
WP_010872135 627 VFLVGLEQGTCPHARSLN--DPLDLEEERRLCYVGITRAQENLFLTHARMRYIWGSLETKIPSQFLQELPPDLLADGSTg 704 Synechocystis s...
CAB92660     655 VFLTGMEDGVFPHMRALG--QAKELEEERRLAYVGITRARERLYLTRSTLRSAWGQPSYNPPSRFLEEIPAPHLEWKRTg 732 Streptomyces co...
3PJR_A       652 ------------------RQAGASRPAVSRPQ---------ASGAVGSWKVGDRANHRKWGIGTVVSVRGGGDDQELDIA 704 Geobacillus ste...
O34580       654 ketrat-----sarkmqpRRGPVSRPVSYASK---------TGGDTLNWAVGDKAGHKKWGTGTVVSVKGEGEGTELDIA 719 Bacillus subtil...
P56255       652 ------------------RQAGASRPAVSRPQ---------ASGAVGSWKVGDRANHRKWGIGTVVSVRGGGDDQELDIA 704 Geobacillus ste...
Q53727       645 ---------------------GKRQ--TIQPK---------AKpfakrgfsqrttstkkqvlssdwnvgdkvmhkawgeg 692 Staphylococcus ...
Q9S3Q0       654 lsrdktq----kktlpfdRKMQRATATTYQATpvtkitngvTGGDQTSWSTGDKVSHKKWGVGTVISVSGRADDQELKVA 729 Leuconostoc cit...
Q9ZD95       650 kqynsfykf----------------------------------------------------------------------- 658 Rickettsia prow...
WP_010872135 705 rrtgrnap-aadpkgpsiAQKQARKKTGSQST---------QPAKDLIWNVGDRVMHNNFGEGTVTHILGKGHKANLAIK 774 Synechocystis s...
CAB92660     733 angpapsapvsgvaaslsSSRSRSRSSASGASgfatgrsagAEQPTVSLAVGDRVTHDQFGLGTVVGVKGSGSNAEATID 812 Streptomyces co...
3PJR_A       705 FPSpIGIKRLLAKFAPIE 722 Geobacillus stearothermophilus
O34580       720 FPSpVGVKRLLAAFAPIE 737 Bacillus subtilis subsp. subtilis str. 168
P56255       705 FPSpIGIKRLLAKFAPIE 722 Geobacillus stearothermophilus
Q53727       693 mvsnvnekngsieldiif 710 Staphylococcus aureus subsp. aureus NCTC 8325
Q9S3Q0       730 FPS-EGVKQLLAAFAPIQ 746 Leuconostoc citreum
Q9ZD95           ------------------     Rickettsia prowazekii str. Madrid E
WP_010872135 775 FPG-IGVKIIDPSFAPLR 791 Synechocystis sp. PCC 6803
CAB92660     813 FGD-TKPKRLLLRYAPVE 829 Streptomyces coelicolor A3(2)
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