Silicibacter pomeroyi SPO2919 and related proteins, uncharacterized sugar phosphate isomerase with a cupin domain
This family includes proteins similar to sugar phosphate isomerase SPO2919 from Silicibacter pomeroyi and Afe_0303 from Acidithiobacillus ferrooxidans, but are as yet uncharacterized. Structures of these proteins show a cupin fold with a conserved "jelly roll-like" beta-barrel fold that form a homodimer.
Feature 1: metal binding site [ion binding site], 4 residue positions
Conserved feature residue pattern:H [EQH] E H
Evidence:
Comment:The four-coordinate metallocenter usually includes three histidines and one glutamate; however, proteins in this subfamily may bind metal via different amino acids.
Jiyao W et al.(2023). "The conserved domain database in 2023.",