2YWE,5IMQ


Conserved Protein Domain Family
LepA

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COG0481: LepA 
Translation elongation factor EF-4, membrane-bound GTPase [Translation, ribosomal structure and biogenesis]
Statistics
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PSSM-Id: 440249
Aligned: 442 rows
Threshold Bit Score: 725.273
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2YWE_A         1 ME-----QKNVRNFCIIAHVDHGKSTLADRLLEYTGAISEREKREQLLDTLDVERERGITVKMQAVRMFYKAKDGNTYKL 75 
WP_041567569   1 -------MKYIRNFSIIAHIDHGKSTLSDRLIQTCGGLNEREMTSQVLDSMELERERGITIKSQNVTLNYKSKSGQPYQL 73 
WP_011520466   1 -------MKKIRNFAIIAHIDHGKSTLSDRFIQLCGALSSREMVNQVLDSMDIERERGITIKAQSVRLNYKALDSQLYQL 73 
WP_014943278   3 IN-----TKNIRNFAIIAHINHGKSTLADRLIQLCGGLYKRDFKNQVLDSLDIERERGITIKSQAVTLFYKSKQGKTYRL 77 
WP_013975426   1 -------MKNIRNFSIIAHINHGKSTLADRLIQTCGGVSEHQIAAQMLDSMELERERGITIKAQSVTLYYKASDGNIYQL 73 
WP_041069517   1 -------MNKIRNFSIIAHIDHGKSTLSDQFIKICGGLSHREMASQVLDSMDLERERGITIKAHSVTLNYKAKNNEVYQL 73 
WP_066284111   1 MK-----LKYIRNFSIIAHIDHGKSTLSDRIIQICGGLSKREMRSQVLDSMSIERERGITIKAQSVTLNYKSLDGKTYLL 75 
WP_067497310   1 -------MNNIRNFSIIAHIDHGKSTLSDRLIQICGGLSKREMSTQVLDSMDLERERGITIKSQSVTLDYKSLDNQVYQL 73 
WP_067568891   1 -------MKNIRNFSIIAHIDHGKSTLSDCFIKICGGLSHYKMADKVLDSMDLERERGITIKSRSVMLKYKALNGQYYQL 73 
WP_111740877   2 TDnkaiaNKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMAEQVLDSMDLERERGITIKAHSVTLDYKSKDGETYQL 81 
2YWE_A        76 HLIDTPGHVDFSYEVSRALAACEGALLLIDASQGIEAQTVANFWKAVEQDLVIIPVINKIDLPSADVDRVKKQIEEVLGL 155
WP_041567569  74 NLIDTPGHVDFSYEVSRSLAACEGALLIVDVTQGVEAQTVANYRIAKEMNLKIIVALNKIDLSTADPNRASQEIKNIIGI 153
WP_011520466  74 NLIDTPGHVDFSYEVSRSLAACEGALLVVDASQGVEAQTLANCYTAIEMNLTVVPVINKIDLASADPNRVLQEIEDIIGI 153
WP_014943278  78 NLIDTPGHVDFMYEVSRSLYACEGALLLIDASQGIESQTITNFYTAFKRDLTIIPVVNKIDLPQASPKYTISNIKKIFNL 157
WP_013975426  74 NFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYKAMEMDLEVVTVLNKIDLPTVEPDRVAQEIEDIIGL 153
WP_041069517  74 NFIDTPGHVDFSYEVSRSLAACEGALLLVDVTQGVEAQTLSNCYAAMDINLEILIVLNKIDLSSGDPQRISQEIEDIIGI 153
WP_066284111  76 NFIDTPGHVDFSYEVSRALAATEGALLIVDSVQGVEAQTIANYYAAIEIGLKVIPVLNKIDLSAAEPDRVAKEIENVIGI 155
WP_067497310  74 NFIDTPGHVDFSYEVSRSLAACEGALLIVDSGQGIEAQTLANCHIAIEMDLKVVPVLNKIDLPSANPDYVARKIEDIVGI 153
WP_067568891  74 NFIDTPGHVDFFYEVSRSLAACEGALLLVDAGQGVEAQTLSNCYTALEMNLEVVPVLNKIDLPSANPDRVAQEIEDIIGI 153
WP_111740877  82 NFIDTPGHVDFSYEVSRSLAACEGALLVVDAGQGVEAQTLANCYTAIEMDLEVVPVLNKIDLPAADPDRAAQEIEDIVGI 161
2YWE_A       156 DPEEAILASAKEGIGIEEILEAIVNRIPPPKGDPQKPLKALIFDSYYDPYRGAVAFVRIFDGEVKPGDKIMLMSTGKEYE 235
WP_041567569 154 DVNNAIQCSAKTGYGIPELLECLIHDIPHPQGDPCAPLQALIIDSWFNQYLGVVSLICIKNGKLYKGDVLKSMNTGQKYT 233
WP_011520466 154 DATDIVFCSAKTGLGISNIIERIVRDIPPPKGDPTAPLQALIIDSWFDNYFGLVSLVRIQNGTLRKGDKVTVMSTGQSYN 233
WP_014943278 158 HFQSVCCISTKLGLGIKVLLETLIKTIHNPKGDPYKKLLALIIDSWFSKYLGVISLVRIFDGNLKKGDQVIINSTGQSWY 237
WP_013975426 154 DATNAVRCSAKTGVGVYELLERLIKDIPPPSGDPAAPLQALIIDSWFDNYLGVVSLVCIKHGTLCKGDKIKVMSTGQLYN 233
WP_041069517 154 SASDAIQCSAKTGIGVIELLERIVRDIPPPQGNPNAPLQALIIDSWFDNYLGVICLIRIKNGTIKKGEKIKVMSTGCIYN 233
WP_066284111 156 DTQQIICCSAKTGDGIQEVIESLIKEIPPPKGDLSAPLQALIIDSWFDNYLGVISLVRIKNGIMVNGKKIKVMNSNKYYN 235
WP_067497310 154 NAIDAVRCSAKTGFGVSDVLERIVRDIPPPKGDPMAPLQALIIDSWFDNYLGVISLIRIKNGTLRKGNRIKVMSTSQFYK 233
WP_067568891 154 DATDTVRCSAKTGLGLFNVLERVVRDIPSPKGDPSISLQALIIDSWFDNYLGVVSLVRIKNGTLRKGDKLKVMSTGQIYC 233
WP_111740877 162 DATDAVRCSAKTGVGVQDVLERLVRDIPPPEGSADEPLQALIIDSWFDNYLGVVSLVRIKNGVLRKNDKIKVMSTGQTYG 241
2YWE_A       236 VTEVGAQTPKMTKFDKLSAGDVGYIAASIKDVRDIRIGDTITHAKNPTKEPVPGFQPAKPMVYAGIYPAEDTTYEELRDA 315
WP_041567569 234 VDQIGIFTPKQVKREILDCGEVGWLVCANKNIIKTPVGDTFTLSTHPAKKACHGFKKLQPYVYAGLFPIGSKNQKIFRDA 313
WP_011520466 234 VERLGFFTPKKIDQEELKCGEVGWLVCSIKNIFGVLVGDTFTLTYQPAQQALPGFKKVKPQVYAGFFPVNANDYQSLNDA 313
WP_014943278 238 IQTVGFYTPKRCLTLKLSAGQVGFFVAGIKDIHGAPVGDTITHANANTDHRISGFKKVKSKIFAGLYPENVKDFKHFSTV 317
WP_013975426 234 ADRLGIFVPKRIERNFLNCGEVGWLVCTMKDINGAPVGDTMTLARQPAKEALPGFKKVKPQVYAGMFPVRSDSYEEFRDA 313
WP_041069517 234 VERIGIFSPKQIDKKELICGEVGWLVCTIKDVFGAPVGDTLTGAYHSADKALPGFKKIKPQVYAGIFPMYSEQYQSFRDA 313
WP_066284111 236 INKLGIFTPNRIYCSQLNCGEIGWVVCAIKDIHGAQVGDTITDAYHHAKQALPGFKKIQPKVFSGLFPINSDNYIAFRDA 315
WP_067497310 234 ADRLGIFTPKRIDREILRCGEVGWLVCAIKDIHGASVGDTLTLACQPADKVLPGFKKIKPKVYAGLFPVNSNDYESFRDA 313
WP_067568891 234 AVSMGVFTPKRIELAVLNCGEVGWLVCAIKDIHGAPVGDTLTFAHQPADKVLPGFKKVKPQVYTGLFPMSSEDYELFRDA 313
WP_111740877 242 VDRLGVFTPKRIDTEVLGCGEVGWVVCAIKDILGAPVGDTLTSAHRSAEVPLPGFKKVKPQVYAGLFPISSDDYEAFRDA 321
2YWE_A       316 LEKYAINDAAIVYEPESSPALGMGFRVGFLGLLHMEIVQERLEREYGVKIITTAPNVIYRVKKKfTDEVIEVRNPMDFPD 395
WP_041567569 314 LYKLSLNDSSLFYEPERSEFLGLGFRCGFLGLLHLDIIQERLRREYSLDLLVTAPMVVYEILTI-DNRIIYVDSPSKLLS 392
WP_011520466 314 LGKLRLNDASLFYEIEQSNALGFGFRCGFLGLLHMEIIQERLEREYNLNLITTAPTVIYEVITH-DKNTYFIDSPSKLPS 392
WP_014943278 318 LERLALNDASLIYTPENSNVYGCGFRIGFLGSLHLEIIKERIEREHGIKIIITLPSVKYKIKLQ-TGKIEYIYDPSKLPE 396
WP_013975426 314 LGKLSLNDASLFYEPEHSTVLGFGFRCGFLGLLHMEIIQERLEREYNLELITTAPTVIYEVLTT-DDHTIYVDSPSKLPP 392
WP_041069517 314 LNKLSLNDASFFYESESSMALGLGFRCGFLGLLHMDIIRERLEREYNLNLITTAPTVIYEIQTN-NNDIFYVDNPAKLPP 392
WP_066284111 316 LAKLRLNDASLFYEPETSTVLGFGFRCGFLGLLHMEIIQERLKREYNLDLITTAPTVIYEVELT-NGDLIHIDNPSKLPR 394
WP_067497310 314 LGKLSLNDASLFYEQESSTALGFGFRCGFLGLLHMEIIQERLKREYNLDLITTAPTVIYEVLMI-DNNILYIDSPSKLPS 392
WP_067568891 314 LSKLSLNDASLFYEPENSTALGFGFRCGFLGLLHMEIIQERLKREYNIDIITTAPTVIYEVLTT-DNKKIYVDSPSKLPP 392
WP_111740877 322 LGKLSLNDASLFYEPENSTALGFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVITT-AGETVYVDSPSKLPP 400
2YWE_A       396 nAGLIEYVEEPFVLVTIITPKEYVGPIIQLCQEKRGIQKNMTYLDpNTVYLEYEMPLSEIIVDFHDKIKSISRGFASYDY 475
WP_041567569 393 -LTKIKEIREPVVLCNILLPKKYLGEIISLCIKKRGTQIDIIYHS-TQVTLTYELPMSEIILNFFDQIKSASHGYASFEY 470
WP_011520466 393 -IHEIKELREPIAKCTILVPHKYLGKVINLCIEKRGVQKDIFYHG-KMVTLTYEIPMAEVVIDFFDRLKSISRGYASLDY 470
WP_014943278 397 -NYKLFKLYEPIVLARIIVPKIYVGNIIKECITFRGKQLCVVFIN-NFIKMIYELPMAEVITNFFNRLKSVSKGYASLDY 474
WP_013975426 393 -LNKIAELREPVAACHILLPQVYLGKVIKLCIEKRGVQTTIIYHG-KQVALTYEIPMSEIVLDFFDRLQSASSGYASLDY 470
WP_041069517 393 -LNNIKELREPVAECNILLPKKYIGNAITLCTEKRGVQRDIIYHG-NHVSIIYDIPLAELVVNFFDTLKSTSKGYASLQY 470
WP_066284111 395 -FNYINELREPIAECKIITPQEYLGNVIKLCIEKRGYQINMVYHG-MQISLTYEIPMSEIILNFFNRLKSISHGYASLDY 472
WP_067497310 393 -FNKIHELREPISECHILLPQTYLGDIITLCIEKRGIQTNIVYHG-NQVALTYEIPMAEVVLDFFDRLKSISRGYASLDY 470
WP_067568891 393 -MNNIAEIREPIAECNMLLPKQYLGSIINLCIEKRGVQIKMVYHG-NHIALTYNIPMTEVVFDFFDRIKSTSRGYASLDY 470
WP_111740877 401 -LNNIDELREPIAECHMLLPQEYLGNVITLCVEKRGMQTNMVYHG-NQVALSYDIPMAEVVLDFFDRLKSTSRGYASLDY 478
2YWE_A       476 EFIGYRPSDLIKLTVLINKKPVDALSFIVHADRAQKFARRVAEKLRETIPRQLFEVHIQVAKGGKVIASERIKPLRANVT 555
WP_041567569 471 KFSRFQRSNIVCIEILINKKRIDALTVITHQEQSIYHGRLLVNKLQKLIPRQQFDIVIQATIGKRIISRGIVKQLRKNVL 550
WP_011520466 471 EFQFFQTSNVVRVDVLINGDRIDALTIITHRVNALYRGRELVDRLQELIPRQQFDIAIQTAIGNNIIARSTVKQLRKNVL 550
WP_014943278 475 EFYRFKKSNMVRLDILINNNRIEALTMIVPFDKAYKQGQFILKRIKLLLSKQLFDLNIKAVSYKKTLAKTQIKAIRKNVT 554
WP_013975426 471 NFKSFKHSDMVRVDVLINGERVDALALIANREQAPQRGRDLVDKLQELIPRQQFEIAIQAAIGNNIIARSTIKQLRKNVL 550
WP_041069517 471 NFKYFQCSDMVRVDILINAEPVDALASIIHRKSAQNYGREIVNKMKELIPRHQFDIVIQAAIGHHIIARSTIKQLRKNVL 550
WP_066284111 473 SFIFFKKSDMVRVDVLINNKKLDALSLITHRKKAIYYGHKLVEKIKNLIPRQQFDIVIQASINDYIIDRSTVKQLRKNVL 552
WP_067497310 471 EFKRFQNAHIVRIDLLINGERIDALGFITHQNNALYRSRKFVDRLQEIIPRQQFDISIQAAIGNHIIARSTVKQLRKNVL 550
WP_067568891 471 GFKKFQNSDMVRIDILINGQRVDALSLIIHRNNALYRGKEFVDQLTKLIPRQQFDIIIQAAIGKNILARSTIKQMRKNVI 550
WP_111740877 479 GFKRFQASDMVRVDVMINGDRVDALALITHRDNSQTRGRELVEKMRELIPRQQFDIAIQAAIGNHIIARSTVKQLRKNVL 558
2YWE_A       556 AKCYGGDVTRKKKLLENQKEGKKRMKQFGKVQLP--QEAFLSVLKVE 600
WP_041567569 551 AKCHGGDITRKKKLLYNQKEGKKRMKQIGNVNLP--HTVFLAVFDVN 595
WP_011520466 551 AKCYGGDVSRKKKLLQKQKQGKKRMKLIGKIELP--QEAFMSILNVK 595
WP_014943278 555 AKCYGGDITRKKKLIEKQKEGKKRMKSIGNIEIKlnKNIFLSLFKTP 601
WP_013975426 551 AKCYGGDVSRKKKLLQKQKKGKKRMKQVGNVALP--QEAFLAILHMG 595
WP_041069517 551 AKCYGGDVSRKKKLLKKQKEGKKRIKQIGNVKLP--QEAFMAILQID 595
WP_066284111 553 SKCYGGDVSRKKKLLQKQKEGKKRMKLVGNVKLP--REVFFVNLNIE 597
WP_067497310 551 AKCYGGDVSRKKKLLQKQKEGKKRMKQVGNVELP--KETFLAILHVS 595
WP_067568891 551 AKCYGGDVSRKKKLLQKQKEGKKRMKHVGNVKLP--QEAFLALLQVG 595
WP_111740877 559 AKCYGGDVSRKKKLLQKQKDGKKRMKQVGNVEVP--QEAFLAILHVG 603
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