Conserved Protein Domain Family
PRK00174

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PRK00174: PRK00174 
acetyl-CoA synthetase; Provisional
Statistics
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PSSM-Id: 234677
Aligned: 432 rows
Threshold Bit Score: 1044.34
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
145591178   1 MSLKSlEKE-TELPFdeyvlndkwrhkytPIDTYFKFHQQAIENlESFWESVAKE-LEWFKPWDKVLDAsNPPFYKWFVG 78 
81300161   15 VFPPS-AEFaSAARI--------------NPEAYEALCQKAAADpVAFWGELAAQeLDWFEPWQQTLDWsNPPFAKWFVG 79 
56750212   15 VFPPS-AEFaSAARI--------------NPEAYEALCQKAAADpVAFWGELAAQeLDWFEPWQQTLDWsNPPFAKWFVG 79 
16331700   14 LFDPP-TEFsERAYVr-------------SGREYEQLYSRAASNpEKFWGELAEQeLHWFKKWDQVLDW-QPPFAKWFVG 78 
113476003  15 LFQPP-EKFvQTAQIk-------------GIEQYKELYEKAKSNpEEFWAELAETeLDWFQKWDKVLEW-QPPFAKWFIN 79 
218248263  15 LFNPS-PEFaENAHIk-------------SLDQYNELYEKAKADpQAFWADLAEKeLHWFKKWDQVLDW-QPPFAKWFVG 79 
220909254  15 LFYPA-PEFaQKAHIq-------------TLEQYQQLCDRAKQDpLAFWAELAQTeLHWFSDWQQVLDW-QPPFAKWFVG 79 
257060413  15 LFNPS-PEFaENAHIk-------------SLDQYNELYEKAKADpQAFWADLAEKeLHWFKKWDQVLDW-QPPFAKWFVG 79 
22298430   15 LFYPP-DDFvAKARIh-------------SLEAYNALYEKAKADpAAFWGELAQQeLEWFQPWEQVLDW-QPPNAKWFVN 79 
158335890  15 LFPPP-ADLaAQAEIk-------------SAEEYEQLYAKAEADpQAFWAELAEKeLDWFEKWDTVLDW-QPPFAKWFVG 79 
145591178  79 GRLNLSYLAVDRHVKTWrKNKLAIEWEGEPldesgyPIDRRKLTYYDLFREVNRVACMLKCnFGVKKGDRVTLYLPMVPE 158
81300161   80 GKLNISHNCLDRHLTTWrKNKAAIIWEGEP-------GDSRTLTYAQLHREVCQFANVLKS-LGIQKGDVVGVYMPMIPE 151
56750212   80 GKLNISHNCLDRHLTTWrKNKAAIIWEGEP-------GDSRTLTYAQLHREVCQFANVLKS-LGIQKGDVVGVYMPMIPE 151
16331700   79 GQLNISHNCLDRHLTTWrRNKAAIIWEGEP------G-DSRIITYAQLHREVCQFANALKS-LGVQKGDRVAIYLPMIPE 150
113476003  80 GKINISYNCLDRHLTTWrRNKAALIWEGEP-------GDSRTITYAQLHREVCQMANVFKQ-LGVKKGDRVGIYMPMIPE 151
218248263  80 GKLNISYNCLDRHLTTWrRNKAAIIWEGEP------G-DSRTLTYGELHREVCQFANAMKQ-LGVKKGDRVGIYMPMIPE 151
220909254  80 GKTNIAYNCLDRHLTTArRNKAALIWEGEP-------GDSRTLTYAQLHREVCQFANALKH-LGVQKGDRVGIYMPMIPE 151
257060413  80 GKLNISYNCLDRHLTTWrRNKAAIIWEGEP-------GDSRTLTYGELHREVCQFANAMKQ-LGVKKGDRVGIYMPMIPE 151
22298430   80 GKINITYNCLDRHLKTWrKNKAALIWEGEP-------GDSRTLTYAQLHREVCQFANVLKQ-LGVKKGDRVGIYMPMIPE 151
158335890  80 GKLNITYNCLDRHLKTWrRNKAALIWEGEP-------GDSRTLTYAQLHREVCQTANVLKQ-LGVGKGDRVGIYMPMVPE 151
145591178 159 LPITMLAAWRIGAITNVVFSGFSADALAERINDSQSRIVITADGFWRRGKVVRLKEVVDSALEK--APGVENVIVLPRLG 236
81300161  152 AAIAMLACARIGAVHSVVFGGFSAEALRDRLVDGQAKLVVTADGGWRKDAIVPLKDSVDQALEGnaCPSVQHVLVVERTK 231
56750212  152 AAIAMLACARIGAVHSVVFGGFSAEALRDRLVDGQAKLVVTADGGWRKDAIVPLKDSVDQALEGnaCPSVQHVLVVERTK 231
16331700  151 AAITMLACSRIGAPHSVVFGGFSAEALRDRLVDAEAKLVITADGGFRKDKAIALKQEVDKALEHg-APSVENVIVVQRTK 229
113476003 152 AAIAMLACARIGAPHTVVFGGFSADALKNRLVDAEAKLVVTADGGWRKDAIVPLKEQVDKALma-gAPSVENVLVVKRTA 230
218248263 152 AAIAMLACARIGAPHSVVFGGFSSEALKDRLEDAQAKLVITADGGFRKDKAIHLKSAVDLALEHg-APTVEKVIVVERIK 230
220909254 152 AAIAMLACARIGAPHTVVFGGFSAEALKDRLVDAQAKVVITADGGWRKDAIVPLKAQVDQALEHggAACVENVLVVRRTG 231
257060413 152 AAIAMLACARIGAPHSVVFGGFSSEALKDRLEDAQAKLVITADGGFRKDKAIHLKSAVDLALEHg-APTIEKVIVVERIK 230
22298430  152 AAIAMLACARIGAPHSVVFGGFSAEALRDRLIDAQAKLVVTADGGWRKDAIVPLKDQVDKALAHqgVPSVENVLVVQRTQ 231
158335890 152 AAIAMLACARIGAPHTVVFGGFSAEALKDRLNDAEAKLVITADGGFRKDKAVPLKTAVDKALADngVPSVNNVLVVQRTK 231
145591178 237 lKDVPMT-EGRDFWWNRLMQgiPPNTYIEPEPVESEHPSFILYTSGTTGKPKGIVHDTGGWAVHVYATMKWVFDIRDDDI 315
81300161  232 -QDIHME-PGRDHWWHELQQ--TVSATCPAEPMDSEDLLFVLYTSGSTGKPKGVVHTTGGYNLYAHITTQWTFDLQDTDV 307
56750212  232 -QDIHME-PGRDHWWHELQQ--TVSATCPAEPMDSEDLLFVLYTSGSTGKPKGVVHTTGGYNLYAHITTQWTFDLQDTDV 307
16331700  230 -ADVTMT-AGRDHWWHELQP--QQSAHCPAEPIDSEDMLFILYTSGSTGKPKGVVHTTGGYNLYTHMTTKWIFDLKDTDV 305
113476003 231 -QKIQME-PGRDHWWHDLQK--SASGECPAEPMDSEDMLFILYTSGTTGTPKGVVHTTGGYNLYTHVTNKWAFDLQDTDV 306
218248263 231 -EPITMK-EGRDYWWHDLKK--TASADCPAEEMDSEDTLFILYTSGSTGKPKGVVHTTGGYNLYTHMTTKWVFDLKDTDV 306
220909254 232 -EPIPMQlGGRDHWWHELQQ--LVSADCPAEPMDSEDMLFILYTSGTTGKPKGVVHTTGGYNLYTHVTTKWIFDLQETDV 308
257060413 231 -EPITMK-EGRDYWWHDLKK--TASADCPAEEMDSEDTLFILYTSGSTGKPKGVVHTTGGYNLYTHMTTKWIFDLKDTDV 306
22298430  232 -QPVTMV-PGRDHWWHDLQK--GVSADCPAEPMDSEDLLFILYTSGSTGKPKGVVHTTAGYNLYTHITTQWVFDLQDTDV 307
158335890 232 -ADVTMA-SNRDHWWHELVP--AASADCPPEPMDSEDMLFILYTSGTTGRPKGVVHTTGGYNLYTHMTCKWAFDLKDNDV 307
145591178 316 YWCTADIGWVTGHSYVVLGPLLMGTTEIIYEGAPDYPQPDRWWSIIERYGVTILYTSPTAIRMFMRYGEAWPGKHDLSTL 395
81300161  308 YWCTADVGWITGHSYIVYGPLSNGATTLMYEGAPRASNPGCFWDVIEKYGVTTFYTAPTAIRAFIKMGEQHPAARDLSSL 387
56750212  308 YWCTADVGWITGHSYIVYGPLSNGATTLMYEGAPRASNPGCFWDVIEKYGVTTFYTAPTAIRAFIKMGEQHPAARDLSSL 387
16331700  306 YWCTADVGWITGHSYIVYGPLSNGATTVMYEGVPRPSNPGCFWDVIERYGVNIFYTAPTAIRAFIRMGEAVPNARDLSSL 385
113476003 307 YWCTADVGWITGHSYIVYGPLSNGATTLMYEGAPRASNPGCLWDVVEKYGVTIFYTAPTAIRALMKMGEQHPNSRNLTSL 386
218248263 307 YWCTADVGWITGHSYIVYGPLSNGATSLMYEGAPRPSNPGCFWDVVEKYGVNIFYTAPTAIRAFIKAGDELPNARDLSSL 386
220909254 309 YWCTADVGWITGHSYIVYGPLSNGATVLMYEGAPRASNPGCFWDVIEKYQVNIFYTAPTAIRAFIKMGEHLPLARDLSSL 388
257060413 307 YWCTADVGWITGHSYIVYGPLSNGATSLMYEGAPRPSNPGCFWDVVEKYGVNIFYTAPTAIRAFIKAGDELPNARDLSSL 386
22298430  308 YWCTADVGWITGHSYIVYGPLSNGATTLMYEGAPRPSNPGCFWDVIEKYGVTIFYTAPTAIRAFIKMGEHLPRARDLSSL 387
158335890 308 YWCTADVGWITGHSYIVYGPLSNGATSLMYEGAPRPSNPGCFWDVVEKYGVNIFYTAPTAIRAFIKLGDQHPQARNLSSL 387
145591178 396 RIIHSVGEPINPEAWRWAYRVLGNEKVAFGSTWWMTETGGIVISHAPGLylVPMKPGTNGPPLPGFEVDVVDENGNPVPP 475
81300161  388 RLLGTVGEPINPEAWIWYHRVIGGDRCPIVDTWWQTETGGHMITSLPGA--VPTKPGSATKPFPGILADVVDLDGRSVPD 465
56750212  388 RLLGTVGEPINPEAWIWYHRVIGGDRCPIVDTWWQTETGGHMITSLPGA--VPTKPGSATKPFPGILADVVDLDGRSVPD 465
16331700  386 RLLGTVGEPINPEAWMWYHRVIGGGKCPIVDTWWQTETGGIMLTPLPGA--IPTKPGSCTKPFPGIVAEIVDLDGNPVES 463
113476003 387 RLLGTVGEPINPEAWIWYHRVIGDSKCPIVDTWWQTETGGFMITPLPGA--TPTKPGSATFPFPGIIADIVNEEGESVDG 464
218248263 387 RLLGTVGEPINPEAWMWYHRVIGKERCPIVDTWWQTETGGIMITALPGA--IPTKPGSATRPFPGIIADVVNEEGHRVPD 464
220909254 389 RLLGTVGEPINPEAWMWYHRVIGGERCPIVDTWWQTETGGIMITPLPGA--IPTKPGSATLPFPGIQAEVVDLEGQPANS 466
257060413 387 RLLGTVGEPINPEAWMWYHRVIGKERCPIVDTWWQTETGGIMITALPGA--IPTKPGSATRPFPGIIADVVNEDGQTVPD 464
22298430  388 RLLGTVGEPINPEAWMWYYRVIGGERCPIVDTWWQTETGGHMITSLPGA--LPMKPGSASKPFPGILADVVDLEGNPVGV 465
158335890 388 RILGTVGEPINPEAWIWYQQVIGGGKCPIIDTWWQTETGGFMITPLPGA--TSTKPGSATRPFPGILADVVDLDGNPVAD 465
145591178 476 GVKGYLVIKKPWPGMLHGIWGDPERYVKTYWSRFPG-----MFYVGDYAIKDKDGYIWVLGRADEVIKVAGHRLGTYELE 550
81300161  466 NEGGYLVIRHPWPGMMRTVYGDPDRFRRTYWEHIPPqngqyLYFAGDGARRDADGYFWVMGRVDDVINVSGHRLGTMEIE 545
56750212  466 NEGGYLVIRHPWPGMMRTVYGDPDRFRRTYWEHIPPqngqyLYFAGDGARRDADGYFWVMGRVDDVINVSGHRLGTMEIE 545
16331700  464 DQGGFLVIKQPWPSMIRDVYGDTDRFRHTYWEHIQPkegqyLYFAGDGARRDKDGYFWVMGRVDDVINVSGHRLGTMEIE 543
113476003 465 NNGGYLVVKHPWPGMMRTVYGDPDRFRRTYWEYLRPkngeyIYFAGDGAHKDEDGYFWVMGRVDDVINVAGHRLGTMEVE 544
218248263 465 NAGGYLVIKHPWPSMLRTVYGNPERFRKTYWDPIAPidgeqVYFAGDSVRRDEDGYFWIMGRVDDVMNVAGHRLGSMELE 544
220909254 467 NDGGYLVVKQPWPGMMRTVYGDPDRFRRSYWEHIPPkdghyVYFAGDGARQDEDGYFWVMGRVDDVISVAGHRLGTMEIE 546
257060413 465 NAGGYLVIKHPWPSMLRTVYGNPERFRKTYWDPIAPidgeqVYFAGDSVRRDEDGYFWIMGRVDDVMNVAGHRLGSMELE 544
22298430  466 NEGGYLVIRHPWPGMMRTVYGDPDRFRRTYWEHIPPrdgqyFYFAGDGARRDEDGYFWVMGRVDDVINVSGHRLGTMEIE 545
158335890 466 NEGGYLVVRHPWPSMMRTVYGDDDRFRRTYWEHIPPkdgkyVYFAGDGVRRDEDGYFWIMGRVDDVINVSGHRLGTMEIE 545
145591178 551 SAFVAHPAVAEAAVVGVPDAIKGEVPIAFVVLKQGVTPTEELRKELREHIRKSIGPIAEPAQIFFVTKLPKTRSGKIMRR 630
81300161  546 SALVSHPAVAEAAVVGRPDDLKGEGIVAFITLESGIETGDELVKDLKKHVAQEIGAIARPDEIRFSEALPKTRSGKIMRR 625
56750212  546 SALVSHPAVAEAAVVGRPDDLKGEGIVAFITLESGIETGDELVKDLKKHVAQEIGAIARPDEIRFSEALPKTRSGKIMRR 625
16331700  544 SALVSHPLVAEAAVVGRPDELTGEAIFAFVSLEGNAEPSEELKKDLVKHVTEEIGAIARPAEIRFTDVLPKTRSGKIMRR 623
113476003 545 SALVSHPAVAEAAVVGKPDEVKGEDIVAFVSLEGGREPDENLEKELKQHVVKEIGAIARPGEIRFTDDLPKTRSGKIMRR 624
218248263 545 SALKSHPAVAEAGVVGTPHEITGEQIFAFVILKNTATPSDELAQELKQHVVMEIGAIARPGEIQFTEALPKTRSGKIVRR 624
220909254 547 SALVSHPAVAEAAVVGKPDQLKGEEIVAFVTLEGTHQPSEELKTELKQHVVAEIGAIARPGEIRFADALPKTRSGKIMRR 626
257060413 545 SALKSHPAVAEAGVVGTPHEITGEQIFAFVILKNTATPSDELAQELKQHVVMEIGAIARPGEIQFTEALPKTRSGKIVRR 624
22298430  546 SALVSHPAVAEAAVVGKPDEVKGEEIVAFVILEGSATPSDALQQELKQHVVNEIGALARPAEIRFTDALPKTRSGKIMRR 625
158335890 546 SALVSHPAVAEAAVVGRPDDLKGEDVFAFVTLENTHPPSDELNSELKQHVVNEIGVIARPGEIRFADALPKTRSGKIIRR 625
145591178 631 LLKAVATGA-PLGDVTTLEDETSVEEAKKAYEELK 664
81300161  626 LLRSLAAGQeVSGDTSTLEDRSVLDKLRQGT---- 656
56750212  626 LLRSLAAGQeVSGDTSTLEDRSVLDKLRQGT---- 656
16331700  624 LLRSLASGQeISGDTSTLEDRTVLDKLREG----- 653
113476003 625 LLRSLAAGQeITGDTSTLQDRSVLDKLRAGS---- 655
218248263 625 FLRQIAAGQeIVGDKTTVEDPTVLDKLEAEIAHKR 659
220909254 627 LLRTLASGSgITSDTSTLEDRSVLDKLREGS---- 657
257060413 625 FLRQIAAGQeIVGDKTTVEDPTVLDKLEAEIAQKR 659
22298430  626 LLRSLAAGQeVVGDTSTLEDRSVLDRLRQGS---- 656
158335890 626 FLRNLASGEdIAGDASTMEDQSVLDKLRQGS---- 656
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