Conserved Protein Domain Family
HutH

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COG2986: HutH 
Histidine ammonia-lyase [Amino acid transport and metabolism]
Statistics
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PSSM-Id: 442225
Aligned: 525 rows
Threshold Bit Score: 394.44
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_067651656   1 Mp-----------A--S-P--------IR-LDGTCMTRADLVAIAR--GRCVVLDEVQLTRVRRAAEFLADKV-HC-GEP 53 
WP_010914596   1 -----------mtA--R-I--------VL-LDAKPLGVADVAEIARr-NARLMLGEEAMRRIRASRALIEHLT-GL-GKP 54 
WP_011482109   1 M-----------------T--------IE-VGETWVGIADLVRVARq-GEAVALAPGARARVAAARDVVVRLA-AS-GAP 51 
WP_011581865   1 Mta--------dfMagQ-TtaelrqgnVRqLTEAALSCAEVAAIAs--GEELVLSPEVRALVEASREIVDEAV-QR-TEP 67 
WP_011582291   1 M-----------------Q--------IV-LKSTGASVDEICAIAg--GAKVAVSDEAIKRIASAYECLSRHS-AT-GKA 50 
WP_014845926   1 MaepvhrrenseeR--PrTgng--plrLT-LNGASLTWRDLASALKaeRVEVELDPVSRGQMLRAREAGLEILeSNpGMR 75 
WP_025437161   1 Mk-----------T--H-G--------VR-MGAAAPSIADIADIARr-DAELFLSPEGLRKIRAGRAVVERYA-AE-NRA 54 
WP_069689641   1 M---------------S-E--------FL-LGAAPVGLGFVMAASRr-GTTVALAPEARDRVVAARRVVERYA-QG-DAP 52 
WP_081508577   1 -----------------------------------MSARTIFKIAHd-FTPVSISPDTAKTIAASYSCLQEHA-AS-GQA 42 
WP_108880589 119 arliagtavpdapD--T-A--------LR-LTGRGLKISDVEAVAVd-GRRVEIADECRERMADGRAIVERYF-AD-NTP 183
WP_067651656  54 VYGVTTGFGSNADKLLGAHRlrdelpggnperqkgtlLEELQHNLIVTHAVCVGKPLAVEVVRAMLAIRVNTLMRGHSGI 133
WP_010914596  55 MYGVTTGLGACVDTPLAQAD-----------------LIAFQHSVPLSHSMGIGPALPTEAVRALMTARISGMAAGGTGT 117
WP_011482109  52 VYGLNSALGANTGALLAEDD-----------------LEDYQRRAVRARAVAVGPAYEQSSVRAMQFARIAGLARGGSGV 114
WP_011581865  68 VYGLNTGLGHRRNERVSAAL-----------------LQDYQPYIIRTHAGAIGAPLSESDVRATMVARIVGIARGGAGV 130
WP_011582291  51 IYGVSTGLGAAVDTRVSPN------------------SGGGQHRIPLARAVGVGHYAGTEEVRAMMAARLARLCLGNAGA 112
WP_014845926  76 AYGWNQALGPFKDRRLEPEE-----------------QLRFQVNVLRSHSTGLGEELPRRVSRLALIIRANCLARGTSGA 138
WP_025437161  55 VYGLNTGLGASVDTALANAE-----------------MIAFQKRVPHNHSVGVGPALPREEVRAMMAARVSGMVAGGSGV 117
WP_069689641  53 IYGLNTGLGGNVAFRLDKAQ-----------------IEAFQVQMVRGRCIGMGEPFPEATARAMGLCRLIGLAQGGSGI 115
WP_081508577  43 IYGVSTGLGAAVDTVM-KVR-----------------TGDDQHLIPRARAVGVGRIATEVEARAMIATRLSRVCVGHSGM 104
WP_108880589 184 AYGLNTGLGVRATDMLSVEE-----------------AAEFSAKMVRGRAQAIGQPLPVPAVRAAMLVRLNTVLSGAAGA 246
WP_067651656 134 RVDTLQALAELLNRGVVPVVPQKGSVGASGDLAPLSHLAIVLLGG--GEAF-V-DGERMPGAQALARVGL-VPQRLSFKE 208
WP_010914596 118 SERVVMGLVAALNAGVHPVIPTWGSIGAA-DLAHLGHMARSLRGD--GEAE-F-QGRIMPSAEALALARL-EPLDLREKD 191
WP_011482109 115 SPGVLDACIALLNHRVHPVVPRFGSIGVA-DLPQLSHLALPLFGE--GEAE-F-GGEVLKGGVALERAGL-QPVKLGAKD 188
WP_011581865 131 GLETLDLLVAMLNRRVHPQVPEFGSVGAS-DLCSMSAIAEVMIGR--GVAM-Y-QGELMPALQALAAAGL-APVRLKPKE 204
WP_011582291 113 STSVVSALASMLNHSIHPLVPMIGSVGEA-DLAPLAHIASVLTGS--GFAY-LpDGTLVDGARAFEASNI-QLPEFGLKD 187
WP_014845926 139 RPELVERMNDAVNLGLVPVMPGTGSMG-TGDLQPMAAAGLALTGDvaGRVRg-dDGEERCAPQAWAAMGRdVEFQLAPGE 216
WP_025437161 118 SEGIVTGIVAALNAGVHPVIPAWGSIGAA-DLAPLAHMGMGLLGY--GLAE-Y-GGSVMPAAEALARAGL-EPLDIHIKD 191
WP_069689641 116 SPPVLDTMVAMFNAGLTPVIPGRGSIGAG-DLGLCAHLGAAVIGL--GEIF-V-NGEKRSAMEALTSAGL-QPATLAAKD 189
WP_081508577 105 SYAVAAALAGMLNHRIVPRVPMLGSVGEA-DLAPMAHIAEVLTGR--GTVIrA-DGSLTDGRTAFLEAGL-ELPKFGVKD 179
WP_108880589 247 SLAVADALRDALNSGVTPVMPATGSIGAG-DLVIMAAVPHALMGE--GDAF-F-DGGRMPGSDALKKAGL-EPLMLGPKD 320
WP_067651656 209 GLALNNGTAQMLATAVLALDRIETLLATADLAAAMTLDAFAGRSGALRPEVHALRPHPGQVETARRLRTLIEGSTLVDip 288
WP_010914596 192 GHAIIVANSLSTGTACLYLEDVAHLIDWALAAVALNYEAFRSSLTAIDEQALAARPAFGQREIGARLRAELAGSGLWQ-- 269
WP_011482109 189 GLALISSNAATTARAALVLHDATAALDAWLAAVALGFEGFRANLSPLHPSAVMARPATGQVEVASQLRALLKGSALLA-- 266
WP_011581865 205 GLALISGNGLAIGAGALTVERARRVLRLADLAGALSLDAYGGNPVPLDSRVQAAKSYPEQAETGQRLRELLAGSAIWT-- 282
WP_011582291 188 GLALVSSNSGSLGLTCLIVREARRVLQSHVTGLALSFEGFRANLHPISPEAVRLRPAPGQAAVSAELLRLLDGGELAG-- 265
WP_014845926 217 AIALISGSAVLTAHLALAVEEVYRQVETLLGAFALFCEAARVERNAFDPRIHAERHMPWEMQANDLILRLIGDSQWTT-- 294
WP_025437161 192 GHALVATNSLSTGVACLCLEDADRALSWSLRAIALNFEGFRGNLAILDEGALAARPAMGQQRAGTYLRDLLSGSGLWA-- 269
WP_069689641 190 GLAILNASAVSCGHAAKVLAELSDILFASVAIAGLTDEGYAANPQIFDARLAAARPAGGQERAAAMFRAVLAGSYLHD-- 267
WP_081508577 180 GLALVSSNSAALGLAALAIADVQRVFAAQVAAVALSYEGFRASIAPLAPAATALRPAPYQGTIAESLLSLLEGGNLME-- 257
WP_108880589 321 GLVLCNNQAHSASLACLAALSARAALDAANISAALVMEGFRANVSPLSSAAAGIRPQAGQVETAKAFRDLLEGSALMQ-- 398
WP_067651656 289 yhlvprfrtwaadawrepedqarrfdiawdwvpssqRHGreafytrfmpfrggKKHQPQDAYCLRCMPQVHGAVRDAWMQ 368
WP_010914596 270 ------------------------------------DK---------------AARRLQDPLSYRCVPQVWGGLLNAFEQ 298
WP_011482109 267 ------------------------------------PG---------------AARRVQDPVSLRVVAQVHGAARGMIAL 295
WP_011581865 283 ------------------------------------PSP--------------TARSLQDPVSFRTIPQVHGAVRRQVCE 312
WP_011582291 266 ------------------------------------GA---------------PARRLQDPISLRSASSVVGSAVAALEA 294
WP_014845926 295 ------------------------------------NEGrrr--------ageTAPRIQDSTSIRSVPHQIGIILRELER 330
WP_025437161 270 ------------------------------------PG---------------AARRLQDPLSYRCVPQVWGGLVHALDE 298
WP_069689641 268 ------------------------------------EG---------------AARSIQDALSFRVLAQIYGPALTSFET 296
WP_081508577 258 ------------------------------------PK---------------AQRRLQDPLSLRCVSSVFGAVQSTICH 286
WP_108880589 399 ------------------------------------DG---------------AARRLQDPISLRSVIQTHGAVHAALDV 427
WP_067651656 369 ASRIIDIELNAVTDNPLIFPDaddpvfaegkaagrpqhiED---QVVSAGHFHGMPLALAMSYVKAALPVLASISERRLA 445
WP_010914596 299 ARLATEIELTHSGDNPVILAE------------------GE---RVISNGNFDLTAMTLAWEQLGQALAHCAVGTANRCM 357
WP_011482109 296 AREQVEMELNSAADSPLVLAD------------------DG---IMLSNGNFHVPALALALDACAIALAQAASMSVARCQ 354
WP_011581865 313 AATVVEVELNSRSDNPLVDVG------------------SG---AILSNGNFQALPIALAFDGLRTGICHIASMSERRCS 371
WP_011582291 295 LESSVTLELSCSDDNPAVLAD------------------ED---LVLPNGNFEPTHLALAIDMLGLALARLAAMAAERMM 353
WP_014845926 331 AREDVTREANSSTCNPLLIPNy-----------------TGeghEFLSGGNWDATVLGHAAQSVNSCLARLAVLTKDLAA 393
WP_025437161 299 ARQATEIELVSSADNPVVLAE------------------AG---RIVTTGNFDMTAFVLSWERLGQAIAHCATGTAHRCM 357
WP_069689641 297 AVESVETEINAAADNPLVMTD------------------DD---LILSTANFQTPAIALAFDTMAIVNTHLATASAYRTI 355
WP_081508577 287 ARDAVALELATSDDNPAINTA------------------LD---LVLPNGNFDPTHVALSFDTMALALARLAAMTGERIM 345
WP_108880589 428 LEAALDVEINHAPDNPAVLVG------------------EN---RIVSTGNYHTPWLSQALDVTARSLAVLANDAVARIH 486
WP_067651656 446 KLVDPATNDGLPAFLIGnEDATDSGF----MIVQYTAAALVNDLATRAHPASvYSVPTSANAEDHVSMGTNEARHVLEMT 521
WP_010914596 358 KLMSPTTA-ELPRFLSA-RGGSRQGY----AELQKPLSALEAEIRHLANPMSlSPLAVSDGIEDQSSMAPRVVAKTAEIV 431
WP_011482109 355 RFMSPALT-GLPLQLTR-HGPAHSGF----ATVQKTLTALWAEIRLRANPGSlDYLPVSEGLEDHACMALGVAEKLGELL 428
WP_011581865 372 HVFRK-----LQAMSSI-DDAIQNAEmpvtSLVAYSAAELSARLRTLAAPASiHVPSLAHDVEDHGSLGPGTIAFTAQSL 445
WP_011582291 354 KLLSPIFS-ELPRFLAP-AEAGSNGF----ATVQKTISALTAEIGHLALPLPfTAPPVADRVEDYASLAFSGADKLKRIV 427
WP_014845926 394 RLLHDGWSHGLPAGLSGgEVGINSGM----LLLHTSAAALIPEIQLLANPVGaLSFPLKGGQEDFHTMAMAAVNGLRANS 469
WP_025437161 358 KIMSPAIS-DLPRFLAA-KGQNRSGY----AVLQKTISALEAEIRHLALPVSlSPIPVSDGIEDQSSMAPRVISKTQDII 431
WP_069689641 356 KMMNHHLS-GLPKYLSP-IGGASNGY----NSLQKTASYLHGEIRLKAAPAScDALPVSESVEDHAPQTALTIRKLEEQL 429
WP_081508577 346 KMMSAEMS-DLPRFMAP-DVGGSNGF----ATVQKTVSALVATIGQQAMPMPfAAIPVADRVEDYASLLMPGVEKFSAIV 419
WP_108880589 487 RLCTPEMS-GLAPLLSS-AATDRAGF----GPLLKPVEAVRANIIHLANPVPvIPSFNAGGVEDAATFTPLAASKLMQLC 560
WP_067651656 522 EDLGHVLALELYTAAQALEYRQ-DmlnaarglaqrggwealaakvanapregeagramfeaevkalrdalaassdFHAGT 600
WP_010914596 432 ERMRYLVAMELIFAATGVELRG-Vv--------------------------------------------------DTMGE 460
WP_011482109 429 ERVRYLIAIELLIAAQAVDLRE-Td-------------------------------------------------qATMGE 458
WP_011581865 446 DLLEMLLAVEIHLSAALADCAGvS---------------------------------------------------DGLGE 474
WP_011582291 428 ERVRLLTAAEMMIAAQAIDMRG-N---------------------------------------------------IRIGS 455
WP_014845926 470 RRFDQLLAVLFVISGQGIHLLE-Erm-----------------------------------------------rgLPLGT 501
WP_025437161 432 KRFHHMIAMELLLSAEAVELRG-Vt--------------------------------------------------DSLGA 460
WP_069689641 430 VPLRMLFAIEAVVAAQAVDIGK-R---------------------------------------------------PRLAP 457
WP_081508577 420 ENLRYLVGIELMVAAQAVDLRT-G---------------------------------------------------ITLGQ 447
WP_108880589 561 EQLSYLLAYELLAGAQALDLAG-P---------------------------------------------------AGVAP 588
WP_067651656 601 QVRAALAKIRERIDFMQR-DRAMDGDVSRIC-ELVAEGGL---VDrgrLV 645
WP_010914596 461 GPQRTFAAVRALVSPLDD-DREMSTDMTRVA-RMVAG-PR---C------ 498
WP_011482109 459 GARATYLQLRDLVAMLDE-DRPLGPDIDRVQ-RAVASGLF---SSw--AV 501
WP_011581865 475 GTRAAYRLAGQAMRRSQEtGRPTTAGIIDLLrNMLIEh-----cA----- 514
WP_011582291 456 GCIQALEDIRAVCPPLDV-DRPTGTDIHALA-GLITCGSF---ARh-sNL 499
WP_014845926 502 GSALIHEQLRTRVTPLDQ-DRVLTPEVDALT-DAIGRGEF----Sv--VV 543
WP_025437161 461 GTLSVQQAIRDRVPALEE-DRELGSSVTALV-NMIMS------------- 495
WP_069689641 458 ATGVLYEAIRASVPMLVE-DRETGLDAMKAL-AVIAQPSF---VA---AL 499
WP_081508577 448 GTAAIQQAVRALVAPLTQ-DRAASPDIVALA-EAIQQQRLgpiLT---EL 492
WP_108880589 589 RIATAHEQVRALSGFLDD-DRPIGREVEAVAcELVLMGRL---AK---QV 631
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