1O4T


Conserved Protein Domain Family
cupin_TM1287-like

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cd02221: cupin_TM1287-like 
Thermotoga maritima TM1287 decarboxylase, cupin domain
This family includes bacterial proteins homologous to TM1287 decarboxylase, a Thermotoga maritima manganese-containing cupin thought to catalyze the conversion of oxalate to formate and carbon dioxide, due to its similarity to oxalate decarboxylase (OXDC) from Bacillus subtilis. TM1287 shows a cupin fold with a conserved "jelly roll-like" beta-barrel fold and forms a homodimer.
Statistics
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PSSM-Id: 380350
Aligned: 77 rows
Threshold Bit Score: 106.399
Created: 31-Jan-2005
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
Conserved site includes 6 residues -Click on image for an interactive view with Cn3D
Feature 1:active site [active site]
Evidence:
  • Structure:1O4T: Thermotoga maritima TM1287 binds Mn2+ and oxalate; contacts at 4.0A

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                          # #    # #                               #    
1O4T_A        39 GEVEMAHLLSkeamhnkaRLFARMKLPpgSSVGLHKHegEFEIYYILlGEGVFHDnGKDVPIKaGDVCFTDsGESHSIEN 118 Thermotoga mari...
AAM35063     269 GPTTAYPFFAdap--dlaFVLRKRVLHkgAGIGLHLHd-KDEIYYIVsGRGLYALdGKQYQVAaGDALLTRpGSTHALQQ 345 Xanthomonas axo...
OJW03079      51 GNTTAYNFFStap--gfkLAFRKRVLHpgSAIGYHLQk-EDEIYYVLsGHGQMEMnGKTFEVQaGDAILTRpGSSHGLKQ 127 Sphingobacteria...
WP_073993667  20 GEVMMIPFLTqeefrgkgRVFSKMILKpgVSIGNHLHegDFEGYYILkGKGKIIDnGREAEVYeGDFALTDdGESHALIN 99  Parasporobacter...
OLD42693      46 GVTTAYSFFArap--nlhLVFRKRALHrgSAIGYHRQd-DDEIYYILsGTGELTLnGRRTVVGpGTAILTRpGSSHGLQQ 122 Gemmatimonadete...
SCJ16593      18 GEIELYPVLNeedlmgkgEVMLRMVLPpgSSIGYHQHlgNFEVYYIIsGEGIFQDqEEERPIRaGEAGFIRpGQFHGLMN 97  uncultured Clos...
CCX46257      22 GHLERYALLSpeemlgagTVCARMVLQpgCEVGEHTHhgNYEVYYFLsGHGVYRSnGETTTVDaGTVTFTGdGERHALRN 101 Firmicutes bact...
WP_027937634  21 GDVTLVHLLQgeefqgkgRLFSHNIINpgCSVGFHQHngDVEAYYVLkGQGVFDDnGAKSTVQaGDLLFTKdGEAHSLVN 100 Anaeroarcus bur...
WP_009378803  20 GHILAAELLNgedfagkgRVFNHCVLKpgCSVGRHRHvgDFEVYHVLsGTGLYFDnGELKPVTaGDVMICKdGEEHMLEN 99  Bilophila sp. 4...
PWL48798      21 GTVILHHFLNqdefygkgRLFSHITVNpgCSVGYHEHhgETEIYAVLsGNGVFNDnGEEAPVTaGDVMITKgGQGHGVAC 100 Clostridiales b...
Feature 1                   # 
1O4T_A       119 TGntDLEFLAVII 131 Thermotoga maritima
AAM35063     346 TGeePLVLLLAYL 358 Xanthomonas axonopodis pv. citri str. 306
OJW03079     128 TGkeDLVIIINYM 140 Sphingobacteriales bacterium 44-61
WP_073993667 100 DTqeDLEIIALLL 112 Parasporobacterium paucivorans
OLD42693     123 AGseDLVIIIAYQ 135 Gemmatimonadetes bacterium 13_1_40CM_2_60_3
SCJ16593      98 TGsgEMVVVAVVL 110 uncultured Clostridium sp.
CCX46257     102 DGpePLEFLALVL 114 Firmicutes bacterium CAG:103
WP_027937634 101 EGpeTLEVIALVL 113 Anaeroarcus burkinensis
WP_009378803 100 DGteDLEFIALIL 112 Bilophila sp. 4_1_30
PWL48798     101 AGscPLELIALII 113 Clostridiales bacterium

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