2KGF,6SSJ,2V4X,3VRL


Conserved Protein Domain Family
Gag_p24

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pfam00607: Gag_p24 
gag protein p24 N-terminal domain
p24 forms inner protein layer of the nucleocapsid. ELISA tests for p24 is the most commonly used method to demonstrate virus replication both in vivo and in vitro.
Statistics
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PSSM-Id: 459864
Aligned: 64 rows
Threshold Bit Score: 54.978
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2KGF_A    15 HHNGFDFAVIKELKTAASQYGATAPYTLAIVESVAD-NWLTPTDWNTLVRAVLSG-GDHLL----WKSEFFEN-CRDTAK 87 
GCF51201 178 THAPFKFQLMKELKTAVSTYGLSSPYAQGLMDNVFS-LHLIPEDLKLLARTLLPP-SALVI----FNNEWAPAlVQQYNA 251
GCF64428  77 THTPFEFQLMKELKTVVSTYGLSSPYAQGLLDNVFS-LRLIPEDLKLLACTLLPP-SALVIfdneWEHEYRER-VPVLVQ 153
RMC20684  98 EYLPFSYQDKKELCKMQKQFGRSSEIFKGMMKATFNsNEMVPSDIKDLFRCLLTP-SEYDL----WEGLWKKA-LKTVLQ 171
RMB97346 201 KWERLDREVVRDLMKAVRDNGLGSPYFKQLLKGTFNiYDLTPFDIRSLATMILSD-SQFIL----WEAKWRKI-LNDYRI 274
RMC04376 152 TWTAIPSQDIKELRKAIKDSGICSPYFKQLLKSTLEgHTLTPNDCKTLAGIILTD-SQYML----WEFKWRRL-LTNVLQ 225
RMC11177  27 TYSLVNPKDVQAIVKAITDRGINSAMVSTLIDSVFGgDDMLPFDIKQTCRLIFDG-AGMIV----FKQEWEDN-CAKQLA 100
P04592   143 VHQAISPRTLNAWVKVIEEKAF-SPEVIPMFSALS--EGATPQDLNTMLNTVGGHqAAMQM----LKETINEE-AAEWDR 214 Human immunodeficie...
CAP72503 128 QWEPLSPRTIQTWVKHIEDRGFG-AECVPFFSALT--DRALTHDINTLLNNIGDHqAAMQI----VKEIVNEE-ITEWDR 199
3VRL_C    11 VHQPISPRTLNAWVKVIEEKGF-SPEVIPMFTALSEg--ATPQDLNTMLNTVGGHqAAMQM----LKDTINEE-AAEWDR 82 
2KGF_A    88 -RNq-qAG---Ng--------WDFDMLTGSGNYS-STDAQ-MQYD--PGLFAQIQ-AAAT-KAWRKLPVKG 139
GCF51201 252 -QLp--PGsarVde------aIMLDGLLGRSTQA-AITTQ-VALH--RPIQEAFV-AAAR-AAFICTPDPT 307
GCF64428 154 -QYnaqLP---Pgsar-vdeaIMLDGLLGRSIQA-AITTQvALHSpiQEAFLRTPdPTGKlQIWGAVRQGP 218
RMC20684 172 -EIq--QT---PdaqdsddndITHDHLCGEGDLS-SANEQiRLLS--KSVLDKIC-NAAE-KTFYQIPSPE 231
RMB97346 275 -KYq--GG---Ana------gFTVAQMAGDPPLD-SAVRQaSFLP--RDVLTDIK-DAAR-KAMVQIPPAG 328
RMC04376 226 -MYr--QCpdvd------lrtLTMSKLTGDPPDD-QNDNQ-VNLP--RIALDDIK-KMAR-EAFVPIQPAG 281
RMC11177 101 -LV---TGadhPlh------gSSLQRLMGTDPTTiTPQAQaKGLR--AHEVMTTT-RAAR-EAIRSASMVI 157
P04592   215 -LHpvhAG---PiapgqmrepRGSD-IAGTTS---TLQEQ-IAWM---TSNPPIPvGEIY-KRWIIVGLNK 272 Human immunodeficiency virus...
CAP72503 200 -THpppVG---PlppgamrnpTGSD-IAGVTS---TMEEE-LAWL---AQQPPIDiGAIY-KRWIIRGLQK 257
3VRL_C    83 lHPv-qAG---PvapgqmrdpRGSD-IAGTT--S-TLQEQ-IGWM--THnppipvgdiykrwiilglnkiv 142
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