1L3J


Conserved Protein Domain Family
bicupin_oxalic
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TIGR03404: bicupin_oxalic 
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bicupin, oxalate decarboxylase family
Members of this protein family are defined as bicupins as they have two copies of the cupin domain (pfam00190). Two different known activities for members of this family are oxalate decarboxylase (EC 4.1.1.2) and oxalate oxidase (EC 1.2.3.4), although the latter activity has more often been found in distantly related monocupin (germin) proteins.
Links
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Statistics
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PSSM-Id: 274565
Aligned: 16 rows
Threshold Bit Score: 605.469
Created: 9-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
1L3J_A        13 GDKGATVKIPRNIERDRQNPDMLVPPETDHGTVSNMKFSFSDTHNRLEK---GGYAREVTVRELPISENLASVNMRLKPG 89  Bacillus subtilis
XP_386788    111 GGLGATDPGPRTYEYEKLNPDLYAPPGTDTGDVPNAMWPLGLSHNRLGSepgAGWARQQNQAVLPAATAMAGVDMRLAPN 190 Fusarium gramin...
XP_001216425  88 GELGGTDPGPRNYAYDRINSDKLAPPGTDSGQTINAQWPMDN----------AGWARQENTNVMPDATKMAGVDMRLEAG 157 Aspergillus ter...
CAG34243      90 GPLGAKIIGPDNLPLDIQNADTLAPPTTDSGSIPNAKWPFALSHNTLYT---GGWVRIQNNEVLPIAKAMAGVNMRLEAG 166 Ceriporiopsis s...
AAQ67425      78 GSLGANILGPQNVAIDKQNPDILAPPTTDQGTVGNAKWPFSLSKQQLNT---GGWVRQQNVQQMPIATAMAGVNMRLESG 154 Trametes versic...
XP_964781     75 NGKGASVLGPWNKDRSRQNPDLVRPPSTDHGNLPSLRWSFADSHIRIEE---GGWTRQTTVRELPTSVELAGVNMRLEKG 151 Neurospora cras...
XP_661167     36 NGKGAPILGGTDLHRDKQNPDNLGAQSTDNGIVPNLKWSFSDSKTRPFP---GGWVREQLVQDLPQSRDISGAQQHLTKG 112 Aspergillus nid...
AAF13275      72 NQLGATIQGPDNLPIDLQNPDLLAPPTTDHGFVGNAKWPFSFSKQRLQT---GGWARQQNEVVLPLATNLACTNMRLEAG 148 Flammulina velu...
WP_011439101  12 GAYGASDPGPRNLALDLQNPDIFIPPPTDNGSLPNLKFSFGMAHNRLEA---GGWAREVTVRELPAAKGMAGVDMRLGPG 88  Rhodopseudomona...
WP_009897208  46 NPQSLTDPGPRNPALMKEFPSFQNPPATDVNGMPIFWASFNNAHKRIQN---GGWAREVTQDDFAISETISGVNMRLTRG 122 Burkholderia th...

1L3J_A        90 AIRELHWHKEAEWAYMIYGSARVTIVDEKGRSFIDDVGEGDLWYFPSGLPHSIQAL-E--EGAEFLLVFDDGSFSENS-T 165 Bacillus subtilis
XP_386788    191 AYRELHWHTSAEWSLVTKGCLRVAAMNEEGKSFVDDLCAGDVWFFPPGVPHSLQAF-D--EGVEFLLVFNDGKFSEDE-T 266 Fusarium gramin...
XP_001216425 158 AYRELHWHVASEWSLVLNGSCRIQAINENGETFIDDVTEGDVWFFPPGVPHSIQAL-D--TGVEFLLVFDDGSFSEDN-T 233 Aspergillus ter...
CAG34243     167 TIRELHWHNTPEWAYILKGTTQITAVDENGKNYLANVGPGDLWYFPEGMPHSLQGTnAsdEGSEFLLIFPDGTFDASN-Q 245 Ceriporiopsis s...
AAQ67425     155 AIRELHWHQTAEWAYVLSGSTQISSVDQLGRNYVATVRQGDLWYFPPGIPHSLQATnDssEGTEFLLIFPDGNFNDDD-T 233 Trametes versic...
XP_964781    152 VIRELHWHKEAEWAYVLEGKVRVTALDYEGGNFIDDLEKGDLWYFPSGIPHSLQGLgD--NGTEFLLIFDDGSFSEES-T 228 Neurospora cras...
XP_661167    113 AIRELHWHRVAEWGFVYEGSLLLSAVDENGRWTTEKLNTGDIWYFPKGVAHNVQGL-D--DENEYLLVFDDGDFEKVGtT 189 Aspergillus nid...
AAF13275     149 AIRELHWHKNAEWAYVLKGSTQISAVDNEGRNYISTVGPGDLWYFPPGIPHSLQATaDdpEGSEFILVFDSGAFNDDG-T 227 Flammulina velu...
WP_011439101  89 VVRELHWHKEAEWGYVLDGRCRVTVVDPDRGVYVDDLQAGDIWLFPSGIPHSIQAL-E--EGCEFLLVFDDGNFSENE-T 164 Rhodopseudomona...
WP_009897208 123 GIREMHWHQQAEWAFMLDGRCRITVLDEEGRPSVQDVKAGDLWYFPPGLPHSLQGLgV--DGAEFLLAFDNGRASEFN-T 199 Burkholderia th...

1L3J_A       166 FQLTDWLAHTPKEVIAANFGV-TKEEISNLPGKEKYIFENqLPGSLK--DDIVEGPN--GEVPY--PFTYRLLEQEP-IE 237 Bacillus subtilis
XP_386788    267 FLVSETFLRNPVSVLAKNFKT-DTSAFKNLPKDQLYIFNG-TPAPKDikEQTVTGSA--GALTGkeSYTYHWSQQKP-HT 341 Fusarium gramin...
XP_001216425 234 FLASEVFAHNPKSVLAKDLGL-PISAFENIPDDELYIFPG-TPAPKDieEQNVTTAA--GVVPLkdSYSYHFSEQPA-HQ 308 Aspergillus ter...
CAG34243     246 FMITDWLAHTPKDVIAKNFGV-DISEFDRLPSHDLYIFPG-VAPPLD--ATAPEDPQ--GTIPL--PYSFEFSKVVP-TQ 316 Ceriporiopsis s...
AAQ67425     234 LLLTDWLAHTPKEVIAKNFQD-NIADWDDIPGSQLYIFPG-VPPPDN--QQPPTSPA--GEIPQ--PFSYAFSEITP-TQ 304 Trametes versic...
XP_964781    229 FLVTDWLAHTPKSVISKNFHL-APEVFAHLPEKEKYIFQGsQPGSID--QERPEGSNv-KKSKY--QFTHKMLAQDP-KV 301 Neurospora cras...
XP_661167    190 FMVDDWIKHTPRDVLAKNFGV-NASVFDTVPEKFPYILNGtIP------EEASSAPQ--GTLTGnsSYVYHTYDHSP-EP 259 Aspergillus nid...
AAF13275     228 FLLTDWLSHVPMEVILKNFRAkNPAAWSHIPAQQLYIFPS-EPPADN--QPDPVSPQ--GTVPL--PYSFNFSSVEP-TQ 299 Flammulina velu...
WP_011439101 165 LLVTELMAHMPIDVVAKNFGI-PQQHFANLPPKEKYIFPLpVPPPLD--EVLAKLPP--KRPAM--PFTVHRGDFTP-TQ 236 Rhodopseudomona...
WP_009897208 200 LLVTDWIAHTPPDVLALNFGV-PASAFRNIPLDNLWIFQGdDPGPLA--AAQRASASsrGAPKR--PFIFSMGDMKPnVK 274 Burkholderia th...

1L3J_A       238 SEG--GKVYIADSTNFKVSKTIASALVTVEPGAMRELHWHPNTHEWQYYISGKARMTVFASDGHARTFNYQAGDVGYVPF 315 Bacillus subtilis
XP_386788    342 VPG--GSVKIIDPTTFPIAEGFSAALVVVQPGAVREIHWHTTSDEWSYFLQGSGRVTVFKAPESARTFDFTAGGVGYIPA 419 Fusarium gramin...
XP_001216425 309 VAG--GSVKIVDPATFPIASNFAAAIVTVQPGGMREIHWHPSSDEWTFFIRGQGRATLFEAPSTATTFDYRAGDVGYFPQ 386 Aspergillus ter...
CAG34243     317 YAG--GTVKIADTRTFPISKTISVAEITVEPGAMRELHWHPTEDEWTFFIEGQARVTLFAGESNAQTYDYQGGDIAYIPT 394 Ceriporiopsis s...
AAQ67425     305 YTG--GTAKIADSTTFKVATKIAVAEVTVEPGAMREMHWHPTQSEWGFFLEGTARVTLFAGTAIAQTFDYQPGDISYIPT 382 Trametes versic...
XP_964781    302 TSG--GQVRITDSKNFPVSKTVAAAHVIIEPGALREMHWHPNADEWSYFISGRARVTVFAAEGNARTFNYLPGDVGIVPR 379 Neurospora cras...
XP_661167    260 VPGqgGTFRRIDSRNFPVSTTIAATIVELEPRGLRELHWHPNAEEWLYFHKGTGRATVFIGDSKARTFDFAAGDTAVFPD 339 Aspergillus nid...
AAF13275     300 YSG--GTAKIADSTTFNISVAIAVAEVTVEPGALRELHWHPTEDEWTFFISGNARVTIFAAQSVASTFDYQGGDIAYVPA 377 Flammulina velu...
WP_011439101 237 WDG--GKTTIIDVRNFPV-TNMAALIIDLEPGALREIHWHPDADEWQYYIQGEARMTVFDATSKARTFNYRAGDVGYVPK 313 Rhodopseudomona...
WP_009897208 275 TRG--GEVRIVDSTNFDVSKTIAAALVTVKPGGMRELHWHPNADEWQYYIQGDARMTVFDTGPKAQTADFRAGDVGYVKK 352 Burkholderia th...

1L3J_A       316 AMGHYVENIG-DEPLVFLEIFKDDHYADVSLNQWLAMLPETFVQAHLDLGKD-----FTDVLSKEK--HPVV 379 Bacillus subtilis
XP_386788    420 ANSHYVENTG-DTDLIFLEVLQAPKFSDISVAQWLALTPRQVVKDHLHVSDE-----FLDSLPKEK--EFIK 483 Fusarium graminearum PH-1
XP_001216425 387 SRSHYIENTG-DEELMFLEVLQADSFTDIALGQWIGSTPKQIVADTLKLPES-----ALSKLKTEK--QYVV 450 Aspergillus terreus NIH...
CAG34243     395 AYGHYVENSG-NTTLRFLEIFNSPLFQDVSLTQWLANTPRAIVKATLQLSDN-----VIDSLNKSK--AFVV 458 Ceriporiopsis subvermis...
AAQ67425     383 AYGHYVENTG-NTTLKFLEIFNSDVFQDVSLAQWLALTPPALVKQHLQLSDA-----TISRFNRTK--GVVV 446 Trametes versicolor
XP_964781    380 NMGHFVENIG-DEPLVMLEIFRADEFRDISLFQWLGETPQRQVADTLFSDDEearqkFLDAIKNPK--KDEV 448 Neurospora crassa OR74A
XP_661167    340 NSGHYIENTSnDEPLVWLEFYKSDRVADISLAQWLALTPDETVANTLKIDIE-----VVKQIKEEK--QLLI 404 Aspergillus nidulans FG...
AAF13275     378 SMGHYVENIG-NTTLTYLEVFNTDRFADVSLSQWLALTPPSVVQAHLNLDDE-----TLAELKQFAtkATVV 443 Flammulina velutipes
WP_011439101 314 TLAHYIENIG-TTPVRVLNVFNKPLFKDVPLNQWLALTPPDLVRGHLGLDDV-----AMAALDRNP--RSVV 377 Rhodopseudomonas palustris
WP_009897208 353 SLGHYVQNTG-TTDLVFLEIFKADRYAEVSLSDWLAHTPPQLVEAHLNVAPD-----VIARFPRNR--PDVV 416 Burkholderia thailandensis
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