Conserved Protein Domain Family
sialate_O-acetylesterase_like2
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cd01828: sialate_O-acetylesterase_like2 
sialate_O-acetylesterase_like subfamily of the SGNH-hydrolases, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the Ser-His-Asp(Glu) triad found in other serine hydrolases.
Links
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Statistics
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PSSM-Id: 238866
Aligned: 15 rows
Threshold Bit Score: 200.584
Created: 7-Sep-2004
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Download Cn3D
 
Feature 1:active site [active site]
Evidence:
  • Comment:by similarity to other members of this super-family
  • Comment:the active site resembles the typical Ser-His-Asp(Glu) triad from other serine hydrolases
  • Citation:PMID 7773790
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1              #                        #                            #                  
BAC56897     43 DIIFLGNSITNggewse--llnnkhVKNRGISGDICMGVYDRLDail-kgkPAKIFLLIGINDVSrgt-saDTIVNRIGM 118 Bacteroides frag...
ZP_00239762  83 GVVFLGDSITNfnewge--afpyvkTYNRGISGDTTIGVMKRLNqvv-alnPSKIFIMIGINDLGaktpkeEILKNYNTI 159 Bacillus cereus ...
BAB73245    206 LSILVGDSLSMwfprek--lpsgklWLNQGISGDTSTGIANRLTafs-ytrPDAIYIMAGINDLRkgtsdeVILRNHRQM 282 Nostoc sp. PCC 7120
NP_935434   120 ELVMYGDSITEwgpwhd--afsgfqVANRGLAGDTTAGMLERIDttl-vcqPKLVCIMAGINDLAqgysvqQVVENYCRM 196 Vibrio vulnificu...
ZP_00539824  69 NSVMLGDSMTNfgdwri--llndptIVNFGIPGDTTEGFLTRLDliv-emkPKRVFLMGGINDIRhftpipTITENMTTI 145 Exiguobacterium ...
BAB72933     67 LSIMAGDSLSLwfpvel--lpedrnWLNQGISGETSRGLLQRLNlfd-ktqPETIFVMIGINDLIrgvndeVILDNQRQI 143 Nostoc sp. PCC 7120
ZP_01092195  77 AVVFLGDSITQgwgdnlggsfgdlkVANRGISGDTTRGMLVRLQedvlslhPRAVVMLMGTNDLEenaepeTIAANFKQI 156 Blastopirellula ...
CAD72143     83 AIVFLGDSITQdwgddfrgafgdrkVANRGISGDTTRGMLYRLKedvldvnPKAVVMLMGTNDLEehatpkIIAGNVRLI 162 Rhodopirellula b...
ZP_00244751  75 RVVFAGDSLVAgwrtlkq-dfpsvpVANRGIGGDVSRGLLFRFQedvldlqPTAVVIQIGTNDLSaqqapaDTVSNLVAM 153 Rubrivivax gelat...
YP_001728    73 NIVFVGDSLIQlfpkelm-vqefpgAVNRGIGGDLTETLLERIEedvlslnPKVIVLEIGGNDLIqgkclhITETNLNRI 151 Leptospira inter...

Feature 1                                                                                       
BAC56897    119 ITQKikqdspkTKLYLQSVLPvtdhy----kmfggHTSRWQEVKKINEGLMYLad-keNVTYIDLYSHFvdektg--kmn 191 Bacteroides frag...
ZP_00239762 160 LEKMkse-lpdTKIFVESILPtkpl-------aksKKLSNEDINWLNKELERVak-enGSTFINLHSLFidkdg---elk 227 Bacillus cereus ...
BAB73245    283 VRRLrqs-hprTQIFIQSILPth-----------lPTISNSRIREINTKLAQIak-keKVNYLDIHSWFtdgdg---nlr 346 Nostoc sp. PCC 7120
NP_935434   197 LAIWqe---qgIEVWVQSTLYvg----------erMSSLNPLVSELNRQLGQIcq-aqSLRFIDLNATLcpeqt----lp 258 Vibrio vulnificu...
ZP_00539824 146 VTTLrk---nnIDVVIQSTLPvapk-------ysdSVRVNRDVEALNRNLEQLak-saGVPFVDLRPELtnqqg---ylq 211 Exiguobacterium ...
BAB72933    144 LRYLrkt-hpkTKIFVQSILPhgaeeatwegreklLAIPNSRIQKLNQQLQSIat-kqSVKYLDLYPLFtnqkg---nir 218 Nostoc sp. PCC 7120
ZP_01092195 157 IAALkqh-naeMPIIVCKVFPss----------akKSRPADKIQQVNQLYEQTvhgdpQVTVLDTWKLFankdg---dak 222 Blastopirellula ...
CAD72143    163 FKELqah-dsdMPIVLCLVMPss----------etKSRPAGKIKRLNKLLAEIaeeneGVHLVDTWTPFanekg---dak 228 Rhodopirellula b...
ZP_00244751 154 IEMArrh-drgLPIIVCTVPPrah---------pqAPIDPAKWRELNAGIRALadrqaGVSVVELAEPLsapdgs--ldp 221 Rubrivivax gelat...
YP_001728   152 LEKIlkf-npnIKIVILGIPPv------------rNQTVNRVSPVLNLTWISIirpykNVEFLDGWQFLrekdrpvldse 218 Leptospira inter...

Feature 1            #  #                  
BAC56897    192 ieYTNDGLHLLGKGYLKWVDIVKPYIN 218 Bacteroides fragilis YCH46
ZP_00239762 228 geWTVDGVHITGEGYKTWENEIKKYIY 254 Bacillus cereus G9241
BAB73245    347 adLTTDGLHLSADGYDVWRFAIQQVEF 373 Nostoc sp. PCC 7120
NP_935434   259 ldCSCDDLHLNSHAYAQWLSVLTPMLD 285 Vibrio vulnificus YJ016
ZP_00539824 212 nrMTYDGLHLVGGGYLRWSDALKPFAE 238 Exiguobacterium sibiricum 255-15
BAB72933    219 seFTTDGLHLSPAGYVVWRTALQVYQQ 245 Nostoc sp. PCC 7120
ZP_01092195 223 aeEFPDLLHPNQTGYAMWAAALRPIFA 249 Blastopirellula marina DSM 3645
CAD72143    229 veEFPDLLHPNEVGYQKWKTTLEPTLK 255 Rhodopirellula baltica SH 1
ZP_00244751 222 ryFATDRLHLSAQGYERWTSALEPALA 248 Rubrivivax gelatinosus PM1
YP_001728   219 fwPGQDKIHVNEKAYRAWIHKLKPILL 245 Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130

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