Conserved Protein Domain Family
HeR

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NF038020: HeR 
heliorhodopsin HeR
This HMM represents heliorhodopsins, a group of phylogenetically distinct microbial rhodopsins, which play an important role in absorbing and transferring light energy for numerous biological processes in bacteria. Heliorhodopsin was initially identified and characterized in a Gram-positive actinobacterium based on functional metagenomics and photochemical approaches. Heliorhodopsin have seven transmembrane domains, and exhibit similar biological function as microbial rhodopsins. However, heliorhodopsin form a distinct cluster based on phylogenetic analyses. Most microbial rhodopsins are hit by the Pfam HMM PF01036, which does not hit heliorhodopsins.
Statistics
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PSSM-Id: 411613
Aligned: 23 rows
Threshold Bit Score: 286.097
Created: 24-Apr-2023
Updated: 3-May-2023
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_048085542      20 LKKLNIGAGALHLIQGLIMIALGLWLTWtqDIYTFYIKfkilslAPPSfQIAPDPTVAFTVSyLGVILASFLLISAIAHF 99  Methanobact...
WP_011011843       8 LKRLNMIAGVFHLIQGVLILLLSSDFTV--TITRNYLKf-----DEATrSLVTVTENLFEVK-LVYLIALFPFLTALSHL 79  Pyrococcus ...
WP_061912808      22 LRRFNLIMGFLHLIQGIFMWVVSNDRTY--PIFTNYLTf-----DRATfTLTPNPQLLYELP-FGPAVAVFLLISAVAHF 93  Bellilinea ...
11_ncbifamImport   1 LRRFNLSMGFLHLIQGILMIVLSNDTAY--PIYTNFLKf-----DTTTmALVPDPKIAAELL-FGPAVAIFLLLSAVAHF 72 
4_ncbifamImport    1 LRIYNLIMGLLHLVQGIIMLIVSNDSSL--TITRNYLEf-----NQEImRLVPATENFMDLK-MGPFIASFLFMSAIAHF 72 
9_ncbifamImport    1 LRIFNAIMCVLHFIQGSLMVILSNEFTL--PLTYSTPVf-----DEITqTISPVSETFFELR-IGPLVALFLFMSAIAHF 72 
5_ncbifamImport    1 LRRWNAVMAVLHFVQGALMVVFAESIQW--PITRTRYEf-----DVATeALAPTTVQWVEVP-LPLLVAGFLFISAIAHT 72 
1_ncbifamImport    1 LRLWNSVMAVLHFLQGAAMVLLADTVLW--PITRTRYGf-----DPGSqSIFPETVAFVDAN-LPLLVAGFLFISALAHT 72 
7_ncbifamImport    1 LRQFNAVMALLHFVQGALMIYLSTPLKW--TVTVTSLEf-----QAGSqRLTPVLEPWTTVQ-LSYLVAAFLLLSALAHL 72 
10_ncbifamImport   1 LRRFNAIMGILHFLQGAVMLYLSSSREW--TITATRLDf-----DTESqQLVPVMESIGAIE-LAYLAVAFLFVSAIAHV 72 
WP_048085542     100 TIAFLKNKNYNENLKKGMNPYRWFEYFFSSSIMLVIIATFVGVWDLWSLVMIFVLNAVTMLCGYLMEKINYYTKETDWSA 179 Methanobact...
WP_011011843      80 AVSTVLFESYKKNLSKGINPYRWAEYSVTSSIMVVIIALLVGISDIGTLMLMFSINAAMIFFGYLMELLNQYTEKVNWSP 159 Pyrococcus ...
WP_061912808      94 YLSTIGYRPYVENLKKGMNPIRFYEYALSSSLMVVLIGMLVGIWDLGTMIAIFGINAMMNLFGIMMEVHNQTTTRTNWLA 173 Bellilinea ...
11_ncbifamImport  73 FLATVGYKLYVSNLKKGMNPVRFYEYALSSSVMIVLIGMLVGIYDLGAIILIFGINAVMNLFGIMMELHNQNTQKTNWTA 152
4_ncbifamImport   73 IVSTFGFGWYARNLQRGINYARWYEYSISSSVMIVAIAMFSGMLDIVSLMLLFTVNALMNLFGLMMELHNQTTERTNWAA 152
9_ncbifamImport   73 LLATILYKWYVNNLKKHINPARWYEYSFSASLMIFLIAMLVTIYDIGTLIALFTLTAVMNLMGLMMEIHNQTTKKTNWTS 152
5_ncbifamImport   73 IVATVRYGAYVRYLERGMNPYRWYEYALSASLMIVVIAMLAGIWDLGTLVALFGLVAVMNLCGLVMERHNELTDRTDWTA 152
1_ncbifamImport   73 AIATVWYDKYVRYLDRGMNPYRWYEYSVSASLMIVVIGMLSGVWDLGTLVALFGLVAVMNLSGLLMEQRNELTEQTDWTP 152
7_ncbifamImport   73 LIATVLYDSYVAYLERGMNPYRWYEYSISASVMIVVIAMLAGVWDLGTLLALFSLVAVMNLMGLMMELHNQTTGTTDWTA 152
10_ncbifamImport  73 LIATVLYDRYVAYLGQGMNPYRWYEYAVSASVMIVLIAMLAGVWDLGTLIALFGLVAVMNLCGLVMERHNRLTEKIDWSS 152
WP_048085542     180 YLVGCLSGFVPWIVLAAYFIAA-LGSTETNPPTFVYAILAIYFIMFNTFSINMVLQYKGVGKWKDYLYGERVYIILSLIA 258 Methanobact...
WP_011011843     160 FIFGSFAGIMPWIVIFMIILRS-------NPPSFVIWIFVSIAVFFNLFPLNMVLQYKKWGKWADYLYGEKVYIILSFVS 232 Pyrococcus ...
WP_061912808     174 FIYGCLAGIVPWIVIFLYFMGA-VNSGDAKPPAFVYAIVPTLFVMFNIFAVNMVLQYKKVGRWKDYLYGERVYIILSLVA 252 Bellilinea ...
11_ncbifamImport 153 FIYGCIAGIVPWIVIVTYFLGS-LAGEGGEPPAFVYAIIPTLFIFFNIFAVNMVLQYKKVGPWKDYLFGERVYIVLSLTA 231
4_ncbifamImport  153 FIFGCIAGAVTWIAVFIYLFTS-LGKANIEFPSFVYAILITFLVFFNSFAINMFLQYKKIGPWKNYLFGESMYVLLSLVA 231
9_ncbifamImport  153 YTIGCISGFIPWVVIFIPLITA------ESVPDFVIAIFITIAIFFNLFAINMFLQYKKIGKWKDYLYGEKMYIVLSLVA 226
5_ncbifamImport  153 YNVGVVAGAIPWVVIAIVLVGS-VVAGDVEVPDFVIYIYVSIFVFFNLFAINMILQYRETWRWRQYLFGERVYILLSLVA 231
1_ncbifamImport  153 YWVGVIAGIVPWITIGVAFVGS-VTASAGEFPEFVIYIYVSIFVFFNLFALNMALQYLEVSRWKNYLFGEKMYIVLSLVA 231
7_ncbifamImport  153 YVIGSFAGLVPWVVIAITIVATvLGSDGGGPPDFVLAIYASLFVFFNLFAINMVLQYRESWKWQDYLFGEKTYIVLSLVA 232
10_ncbifamImport 153 FIVGSIAGVVPWIVIAVSIIGT-FNAG-GSPPDFVIIIYVSLFVLFNLFAINMLLQYLGVWKWQDYLYGERAYIVLSLVA 230
WP_048085542     259 KTALAWLTFVGIF 271 Methanobacterium formicicum
WP_011011843     233 KTILVWQVYAGTL 245 Pyrococcus furiosus
WP_061912808     253 KTVLAWLIWFGTL 265 Bellilinea caldifistulae
11_ncbifamImport 232 KTVLAWIIFAGTL 244
4_ncbifamImport  232 KSVLAWQVFAGTL 244
9_ncbifamImport  227 KSALAWQVFAGTL 239
5_ncbifamImport  232 KSALAWQVYFGTL 244
1_ncbifamImport  232 KSALAWQVYFGTL 244
7_ncbifamImport  233 KSLLAWQVFFGAL 245
10_ncbifamImport 231 KSLLAWQVYFGAL 243
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