Conserved Protein Domain Family
GlmS

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COG0449: GlmS 
Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains [Cell wall/membrane/envelope biogenesis]
Statistics
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PSSM-Id: 440218
Aligned: 776 rows
Threshold Bit Score: 626.655
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_014436395   1 MCGIVAYVGS--K-P-CLPVLLEGLKRLEYRGYDSAGVAVLRpahageagpGV-TTTAREVGRVMNLENAIAPRTagFAG 75 
WP_048064125   1 MCGIIGYIGN--E-K-ASKILLKGLKRLEYRGYDSCGIATID---------DT-IKLKKNTGKVLEVSKKENFED--MTG 64 
WP_013143227   1 MGGIFGVICR--E-KiRGRVVFEGLRRLLYRGYDGVGVAFLDd--------MGnIVVRKKPGHLEKIADE-GLFN--ISS 66 
WP_020962980   1 MGGIFAAISKssE-N-TVPIVIEGLRRLKYRGADNSGIAVLLd--------GR-IEIFKEAGSIEAVSAKLGLEN--ISS 67 
WP_103287721   1 MCSIIAYKGY--R-D-AAPLIVKALSRMEYRGYDSVGIATAHn-------nST-IMVKKGVGNVGYVNSRLNLDR--MHG 66 
WP_013129928   1 MGGIFAAVCK--E-KiPEGVLYNGLRRLVYRGYDGAGVAFLRg--------DK-IVVWKSPGHLEKIAPQLNYLN--TDS 66 
WP_012609125   1 MGGIFGVICS--T-TiPRGLIVTGLRRLLYRGYNGIGVVFPVd--------KG-LEIRKAPGHLDDVVKQVDLEN--IPS 66 
ALM09820       1 MCGIIGYVGKr-T-D-AGFLVVEGLKHLEYRGYDSWGVACKTk--------DG-IAIRKDVGKISTVNPAEFLK----SC 64 
WP_013867144   1 MCGIIGYIGN--R-K-ASEILLKGLKRLEYRGYDSCGIGIIDn--------NN-LIIKKDVGRVEEVAKKEDFLG--LNG 65 
ALI37445       1 MCSIIGYSGK--LiS-AAPLLVESLKKMEYRGYDSVGIATLNd--------GN-ILVSKGVGKVAEVDKEMDLNK--LPG 66 
WP_014436395  76 TTGIAHTRWATHGKVTRANAHPHAGVTAeglTLSVVHNGTIENYASLRTLLQNKGVTFASETDTEVIAKLIADR-YD--- 151
WP_048064125  65 FIGIGHSRWATHGGITKNNAHPHYDCSE---KICIAHNGIISNYKELKELLISKGHIFKSETDTEVIPHLIEEE-IKdfk 140
WP_013143227  67 RIVLGHTRYASRGWPTIENTHPLTDCTG---KIAVVGDGLIENYEAYKEELVRKGHSFASRTDTEVYAHLLEEAvFR--- 140
WP_020962980  68 RIVLGHTRFATHGRPTVENAHPHTDCER---RIAVVGDGSLSNYEDLRDKLLMEGHKITSRSDFEVVAHIFESL-LN--- 140
WP_103287721  67 RVGIGHTRWATHGVVSDINAHPHVSCDG---RIAVVHNGIVENYAALKYALASEGHVFRSDTDSEVIAHLLEDA-FT--- 139
WP_013129928  67 DVAVAHTRYASRGWPVLENTHPLLDCTG---RIAVVGDGIIENYEDYRKVLEDRHHQLKGRTDTEVAAHLLEEA-LA--- 139
WP_012609125  67 RIALAHTRYASRGWPVYENTHPLTDCNG---GIAVVGDGIIDNYEAYRTELEKEGHILRSRTDTEIAAHLLEKY-YT--- 139
ALM09820      65 SLAMAHTRWATHGGVTQENAHPHVSCDG---KIVVVLNGIIENFETLREELKAKGHRFVSTTDTEVIPHLIEEE-MK--- 137
WP_013867144  66 NVAIGHNRWATHGHVSKENAHPHTDCKA---ELCIVHNGIISNYKKLKKELISKGHKFKSQTDSEVIVHLIEEE-LKkyk 141
ALI37445      67 QIGIGHTRWATHGSVNDKNAHPHYSCSS---NIAVVHNGIIENYQELKTELTRDGHTFKSQTDSEVIAHLLEKC-YQe-- 140
WP_014436395 152 --AEPeggdqpspgeslsgfipstRLERATKAALRRVTGAYAVAVVCDANPHELVAARKGSPLIVGI--AD--------- 218
WP_048064125 141 eiTEK-------------------TYINAIQNTIKKLNGTYALLILNQDFPEMLVGVRNESPLILGI--KK--------- 190
WP_013143227 141 --ERR-------------------DPLEATARYMRELRGMYGIAAIIAGK-ESFYVAHNGQPLVVGLthSN--------- 189
WP_020962980 141 --KEY-------------------QSSEFLKEIYSKMEGYFSFAVLEAEK-QRIIATTNGPKLFYGL--SD--------- 187
WP_103287721 140 --EPQsd---------------eeEMLGKLVNVLNLLNGSYSFVALVSN--GMLVGARYHEPLIIGL--TNpskddgddg 198
WP_013129928 140 --KGV-------------------NVLEVLQTLSKQLKGIYSLVFLIEPY-RKLFFIANGQPLVIGI--GE--------- 186
WP_012609125 140 --MER-------------------DLLRALLRIGSELKGLYSLAFLVSGV-DGILFIQNGQPLVIGI--GS--------- 186
ALM09820     138 --HEP-------------------DFAAAVRRACLKFEGRFGIVVMH-AESETLVAARTGSPLIIGV--AA--------- 184
WP_013867144 142 npSEE-------------------DYINAVKEVSKKLEGSYAILILNKNFPHLLVGLKNESPLILGV--KE--------- 191
ALI37445     141 --SDS-------------------NVKETMMKTCQALKGSFAFVAIFEN--GIIAGARFDEPLIVGI--SD--------- 186
WP_014436395 219 --------NGFVVASDGAAIVSHTTAAVTLADYQVVRLAagpagstdaagerhaaawADP-------------------- 270
WP_048064125 191 --------DECFIGSDISAFLEYTKLAMPLNDRDIVILR------------------KENd------------------- 225
WP_013143227 190 --------ECVYLSSDIPSLYGYADEALILEEGMAAEIS------------------IDN-------------------- 223
WP_020962980 188 --------KYVLLSSSQYALHGFADQYGELSPGELIILS------------------KDG-------------------- 221
WP_103287721 199 gddsilyaDECFIASDVLAFIEYTDKAVFLADGEAFLVRy-----------------ADAskq----------------- 244
WP_013129928 187 --------KCYFVSSDIPSLYGFAETAYMIEDGTIGWVD------------------AQG-------------------- 220
WP_012609125 187 --------QCVYLSSDLTSLHGLADTAYIIEDGMAGLIS------------------LEK-------------------- 220
ALM09820     185 --------DGYFIASDTPAFLEYTSTVQYLDDGEMVVTD------------------GES-------------------- 218
WP_013867144 192 --------DECFLGSDISAFLEWTKEIIPLEDGDIVVLR------------------KYNpnnncnsskinnksinnknn 245
ALI37445     187 --------SALFLSSDVLGFLKYTDKSVFLDNGDIVIID------------------HNT-------------------- 220
WP_014436395 271 ----------L--HTTTL-D-DEL----L--TAEVGELEMQLEEIELGGYPHYMIKEIMGQPESLRTCFRGRVDTrdgrv 330
WP_048064125 226 ---------eIdiEVLNY---GKQ----V--QRDTIELQWDMESAEKEGYEHFMLKEIMEEPVILKNSMK--ISK----- 280
WP_013143227 224 ----------I--RIINA-E-NMEptsiE--KLIRKRVKYQVELVGKAGYPHYMLKEIYEIPDSMVRTTYSLME------ 281
WP_020962980 222 ----------P--TIYTS-E-GLA----K--QVQSLPLQLDPILVEKGGYKHHMLREINEVPEALLRTLSSVQK------ 275
WP_103287721 245 -------rvmV--KIFDR-N-GNV----T--NKEITQIAWEFADVDKGRFAHYTLKEIHEQRYTIGKAFNA--SD----- 300
WP_013129928 221 ----------F--TAIRTaD-G-SvltpE--RLQGKRVKYFAEAGEKGGFPHFMLKEIYESPEALNRVLLAVME------ 278
WP_012609125 221 ----------Q--VLYRI-StG-EhvdlA--SLQSKRVKYGIEYVEKAGFPHYMLKEIYETPDAIYRTTIAIMD------ 278
ALM09820     219 ----------I--LFSDIkT-GVV----R--EKREITITWSAAQSQKGEYEHFMLKEIMEQKGSIARAVNQD--E----- 272
WP_013867144 246 nksdkigavsVsySIYNK-N-NN-----ItnERKKITINWDIESAEKAGYDHFMLKEIMEEPDVVKNSSI--ICN----- 311
ALI37445     221 ----------Y--RIFDL-N-KRI----V--ARPITQVAWELGSTEKGKYAHHTIKEIHEQSLTLLKPFQE--------- 271
WP_014436395 331 vLGGLTGLSRELVRAKRVALIGQGTAFHAGLIGEYLFEDLAKIPARAHYASELR-YRN-PIIEEGT---VVVAVSQSGET 405
WP_048064125 281 --LEIENLGKEIEKCDKIYITAMGTSLHAAMVAEYWFSGLNKLVIPI-DSSEFL-TK--GIVDEKT---LVIAITQSGET 351
WP_013143227 282 --KYLRLAAMIIYGAKNVYVIGNGTSLHAGMVSSYYFTDLANINVNVVSAAEFP-YYAlKNVSTGT---VIIAISQSGET 355
WP_020962980 276 --RYLNLAGRLVTGADNIYIIANGTSLHAGMIASYYFSELAGISPIVTSAAEFPlYYL-ENVGPGT---LVIAISQSGET 349
WP_103287721 301 --DRLRELINVLINADRIIVTGSGSSYHAALIAKHLFSKLCMLACDAIVASEFI-YSI-DTYANNAgkpLLIAISQSGET 376
WP_013129928 279 --KYLHLASMIVYGAKNAFILANGTSLHAGMIGSYYFNDLAGVSVDPVSAAEFP-YYAlETVETGT---VVIAISQSGET 352
WP_012609125 279 --KYLRLASMIIHGARDVYIVANGSSLHAGLVASYYFAELAGISITPVSAAEFP-YSIlESITTGS---VLIAVSQSGET 352
ALM09820     273 --EQIETLARAILGAQGTFLVGCGTAAKACMAAEYFFSVIAGHHVNFAPASEFK-LYH-RFLKPES---LLIAVSQSGET 345
WP_013867144 312 --DEIKELAKALHEYNRIYIVAMGTSLHASMIAEYWFSKLNKLVIAC-DSSEFL-IK--GIVDKNT---LVIGITQSGET 382
ALI37445     272 -FNDFQNFCEFIRDASNVYITGSGTSYNCGLLGKQLLSKFAKIKTEVIMSSEFQ-YYS-DSLEPNS---VVIAISQSGET 345
WP_014436395 406 ADTLAAIAEAKDRGALALGAVNVVGSSIPRETDAGVYLRVGPEIGVASTKAFVGQVAVLTMMALYMGKRR-YLSQADLDG 484
WP_048064125 352 YDTMKAVKYAKEKGAKTATIVNVLGSTATREADITIMMGSGLEIAVCATKTFMSQLVILYRLFIEYGKIIgK----NMDI 427
WP_013143227 356 SDVIKSVKLAKQYGAVIIGVTNVVGSRLSLESNVYLPIGAGPELAVPATKTFVSSLVALALLAGYTGLYTgKLSRDEYAG 435
WP_020962980 350 GDVLSSLYEAKLRGATILGITNYVGSRLARLSNLYLPIAAGPEIAVPATKTFTSTLQVLYLVALSSSRQKgKIEESEQKA 429
WP_103287721 377 ADVLNAVRIARGKNFRIASIVNAPLSTLARESDIYLSINAGPEIGVAATKSFTAQMALLYRMSIEASRSNgM------NP 450
WP_013129928 353 SDVISSIKLAKQRGAVVIGITNNVGSRLALESNVYLPIGAGPEIAVPATKSFTATLATLLLFASYTGMFTgKTSRDDYRR 432
WP_012609125 353 SDVINSVKLAKQRGAVIIGVTNNVGSRLALESNVYLPIGAGPEIAVPATKSFSSTIAALLLLASYTGIFNgRQSFNDYNT 432
ALM09820     346 ADTLEAMKIAKAKGAKVLAIVNTEGSTIAREADFTLHINAGPERAVASTKALTGQMAVLLLIAYAMIGKLp--------K 417
WP_013867144 383 YDTVKAIKYAKEKGAKTATIVNVLGSTATREADITIMMGSGIEISVCATKTYLSQLMILYRLFIEYGEIIg----KDMSL 458
ALI37445     346 ADVLHSVKKAKENGAKILSIVNVPTSSLARMSDSILTLNCGPEIGVAATKSFMGQLMLIYKIVNILSSGQmPFDKFN--- 422
WP_014436395 485 YLAELERIPDHVAEIVQ--Q-SD--HIKEAVEDV-VTRDNWLFLGRGYNYPVALEGALKLKEISYIHAEGMPAAEMKHGP 558
WP_048064125 428 FEKELLNIPNYISKVLD--E-KE--NISKIAEEL-T-AKNYLFISKGINLANALEGALKFKEITYLHAEGMSSGFLKHGT 500
WP_013143227 436 ITEKIRGTAKALRKDLK--VyDN--TAEKIAEKL-LGWRNMYVSSSGINYPVALEASLKFKEASIIHAEGVQLGELRHGP 510
WP_020962980 430 RLEAIKKLAQSLDERLA--FiDS--EATKAAEKI-SLCRSGYVVSRGLTYPLALEGALKLKEASYFHAEGVEAGEFKHGP 504
WP_103287721 451 LTLDIGSSNIYVDKILG--M-EA--YISDLAESI-KNVNSIYIIAKGIHHVIALEGALKLKELAYVHAEGIHAGELKHGP 524
WP_013129928 433 IVEEIKNASALLKEKIP--EfDK--NAMNIVQLN-YNWGGAYVASSGINYPLALEGALKLKEAAIIHAEGFQLGEMRHGP 507
WP_012609125 433 IINEIRNTSKELKELIT--RfDS--RITSIVNSL-PLFYNVYVAGSGITYPIALEGALKLKEAALIHAEGVQLGELRHGP 507
ALM09820     418 GRTRLLETAAAINDMLNprY-MQ--FIEMIAERI-QESSDLYIIGKGWNYPMALESAIKIQEVSYVHAEGFAGGELKHGP 493
WP_013867144 459 YRNELKNIPEYIKEVIS--E-KEriNIKNIAKKL-T-AKNYIFISKGINLPNALEGALKFKEITYLHAEGMSSGFLKHGT 533
ALI37445     423 ----QRNLLMMVKKVLN--S-DG--IIQNLVSSLdTNIKDIYILGRSIHYPIALEGSLKIKELAYIHAEGIAAGELKHGP 493
WP_014436395 559 IALIDEGMPVVFVAT--GGSQY-SK-VISNIEEVKARGGRVLAVADEGDTQIDRYaD---HVFRVPPVSEPLQPLLTVVP 631
WP_048064125 501 ISLIDENMDTVALIPpsKSELL-NS-VLSNVEEIKARNGKIIGISPVE-----DNlK---YSIKVPDVIEEVSPFVYATA 570
WP_013143227 511 LVLIRDNYPVIIIKP--IEEEA-LPlYNRVAEYVLSKNGFLVTITHD------ETgYg--EVVKVKPTHKILSPITTIIP 579
WP_020962980 505 FVLVEQGFATIFIMP--VEKVSaEA-TFPSIEMARQTGATVVVIGSENNQKLLELsQdgvTTIRAVETERHLAPISLAVP 581
WP_103287721 525 LALIDGKSIVIALNP--MDDTY-SD-VLASIHEAKARGACIIGVSDSRC----NMyD---FTLEIPRVDRLLYPLYEVIP 593
WP_013129928 508 MVLVSRDFPMVLIEP--AEEQA-KPlYVKVLEEARNKGAKPIVIGPG------RLgDs--VTIQTPSVPRYLSPIVSSIP 576
WP_012609125 508 LTLVSHEFPVILIEP--FEEPA-KQlYLKVVKEVLNRDAILFSININ-D--V-PCkN---ICVEVPG-KKYLYPVIATIP 576
ALM09820     494 IALIEKGTPCIALVG--NDEVR-TD-IISNAIELKARGGFIIGISPERH----EVfD---EWIKVPDVDTA-QAIVNIIP 561
WP_013867144 534 ISLIDENMDTIALVPpsNSNLF-NS-VVSNIEEIKARNGKVVGISPVDI----DMvD---YLIKIPNVLEEVSPFVYAPA 604
ALI37445     494 LALIDKESVVVVLNP--TDETY-QD-VISSSNEIKSRGAYIIGISNKKN----EVyD---RFVELPDVDSYLYPILEIIP 562
WP_014436395 632 LQLLAYHAAVLRGHDVDKPRNLAKSVTVE 660
WP_048064125 571 CQLLAYYKAVDLKRDVDKPRGLAKSVTVE 599
WP_013143227 580 LQLIAYHLGVKQGYPVDTPPGLAKAITT- 607
WP_020962980 582 LQLLAYRLGEKLNRPIDTPRHLVKAV-TQ 609
WP_103287721 594 LQLLAYHMALKRDCNPDYPRNIAKSVTVK 622
WP_013129928 577 IQLLAYRLGVAFNRPIDTPPGLAKAITT- 604
WP_012609125 577 LQLFSYRIGVKLGRPIDHPPGLAKAITT- 604
ALM09820     562 VQVLAYFLAVKRGKDPDMPRNLAKSVTVK 590
WP_013867144 605 CQLLAYYKAVELGRDVDKPRGLAKSVTVE 633
ALI37445     563 LQLMSYYLALKKQVDPDYPRNLAKSVTVK 591
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