Conserved Protein Domain Family
Rcd1

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pfam04078: Rcd1 
Cell differentiation family, Rcd1-like
Two of the members in this family have been characterized as being involved in regulation of Ste11 regulated sex genes. Mammalian Rcd1 is a novel transcriptional cofactor that mediates retinoic acid-induced cell differentiation.
Statistics
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PSSM-Id: 461160
Aligned: 52 rows
Threshold Bit Score: 223.995
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002642224  33 WIIDLRDPSK--REFALLELSK--------KRDSVPDLPLWLWHSFGTMSALLQEVVAIYPAIM---------PANLTA- 92 
EPR79231      11 FIINRE------RFQYLEEISK--------LLLTDPERAQDIWCYGTMPLVLLDEVVKSYLVFD---------YKEIPE- 66 
EIJ89296      15 IIRNEN------KDESLKQLRT--------ILSEKAECKSRIVQEFGILTVFLKDISSIYEYLT-------------LEr 67 
EOB12694      19 LLKDSN------KTIHLEKLLS--------FLSKNQIYSLLVWESNGIPILLLQEVVNPYFELG---------TQSFNE- 74 
Q8SWP5        55 VVSNPK------ETSKLDELFE--------RLKKSPGMALEIWRYDSMPIFLLQEVVAPYMILS---------TSKFDE- 110 Encephalitozoon...
XP_009144001  43 WINDLHNEIPfvSNSALQNLVT--------HRNTYEILPLLLWKSPCTMAMMLQEIVKIYPHIStpv----hsrE----- 105
Q58FZ9        52 WVCDIHKPKSymSDFALHNLAY--------HRNDFEFLPSLLWESKNTVYIMLQEVFEAYRHLAghislrlfpHP----- 118 thale cress
XP_006843443  61 VILDLQ--REenREYALRCLSSflilrredDPENYQRAGFFLFNSCATMTILLQELVSAYWKMV---------DGSLTV- 128
EDW24345      20 WILDLC--SKedRPLAMLELCE--------RRRIIVNLGPMLWQSFGAVAGLLQEVIDVYPAVS---------ANSLDD- 79 
XP_653602     63 LIADLADIEK--RLDSLNALSV--------IADKHPDLAIPLWYSYGTVVILLEEIVSVYPYISgkhketlavSSY---- 128
XP_002642224  93 -AQSNRVCNALALMQCVA-SHRETRGPFLHAHIPLYLYPFLHTTKVSRSFEYLRLTSLGVIGALVK-TDDKEqllvVINF 169
EPR79231      67 -EEYNKAVMVLNVLQTLV-EDRLVRREFIFTDFPIFILPFLNSRKFTRELESSRLAALGVIGTLVK-DGDVD----IINY 139
EIJ89296      68 aCLPENIYTVLEIIILLT-DEDKFISYAIDSNLLLFLYPIINSSIRNEEIEELKYITLRIIKCILQ----RNkiehLIEF 142
EOB12694      75 -DKAKNLILVLKILEILLlEDKSIKKVFVDSCFHYYLYKYITIYEQAPVYENLRKLTLNVLYALLH-NSDLH----VHNQ 148
Q8SWP5       111 -RECHRLYTVLNILQILV-SEPKIKKVFVDARFPYYIYRYLVMSDSNSKHETLRISALGVIASLLQ-NGDQY----IHKQ 183 Encephalitozoon...
XP_009144001 106 -GKPPRAYNILLLFQCIA-HYPETRGYFLKAEMPHYLFPLMDINLTDKPIECLRLGALGVLAHMLKaPIDGA----AVRF 179
Q58FZ9       119 -LNPLRVYNVFLLFQSMA-CHPDTSRQFLRAKMPNYFYPLMDTGLIDKSDECMRLAALGVIAHMLKaSEDGA----VNRY 192 thale cress
XP_006843443 129 -RETRRLGNVLTLFQSVA-ANNETRLKFVQAFIPNFLVPLILFESTEEAYENIRGMSLSVIGIICQ-EREPD----IIKW 201
EDW24345      80 -QQSQRVFAALSLFLSMA-KHPDTGVLLMRTHVFYYLMPLLRLTQKTRPIEHVRLSVLIIICGLLK-KNTTE----IICY 152
XP_653602    129 -SLIQRVCKALALLQTIA-SHPKTQHFLIGIDIIYFLTPIFALTQVEREIEYLRLTSLGVIGAMSK-TRDPQ----IVKY 201
XP_002642224 170 LLSTEIIPLCLRIMEQGTELSKTVATFILQKILLDDTGLLYIC--QTYERFSHVAMILGKMV---MKLTREP---SVRLL 241
EPR79231     140 LKDTDIVPLTLKTMDSGSEISKAISGYIFLKILQTRDGLESLT--ARFEKFMLICDVINSMItnaIKKs------SKRIL 211
EIJ89296     143 FKNTELVPLCLRNMELGRKKTKIEASEVFYLIISVQEGLEYSC--QTYDRFMAISMILNSVLvqmETIq------SPKLL 214
EOB12694     149 MKNTEIVPIILKSIDLGTEAVKIQSIDLFFKIVSSEDGLNYAC--QTFDRFSAINQVLNSVMyhaVQIk------SSRII 220
Q8SWP5       184 LKTTEVVPLLLKIVDLGSEASQLLSANIFGLIIGNDDGLNYAC--QTFDRFSAINLMFNSLAsqaVSLg------STRLI 255 Encephalitozoon...
XP_009144001 180 LMDNGALRYCIKAIEIGSTESKTVSVFILNKILSTNEGLQYCC--VLADRFFLIDGLLKNLLvylSSM-TNP---SPSLF 253
Q58FZ9       193 LMESGVVGFCVKPIEFGSTETKKVALYILDKIMSTDQGLYYCC--VLADRFYVIDELLKKVLfylSNM-VRP---PSSLF 266 thale cress
XP_006843443 202 AVDNNIVEICRRGIQIGGELSKVIAMHIIEAILQDKSGISYICkpEADHLLKNLLETWEHMV---MVL-SVNkdhSPRLL 277
EDW24345     153 TMAAELIPQLLRQLEHGSSISKTLSSFILYRILDNAVGLKFAT--RRLSRRTHLIHTLGRVI---HQQTLEP---DPRIL 224
XP_653602    202 LMDKEVLMICIVSIQHAAEISRVIATFILSKLFSESTALENVC--ETPQKILSIANLLCHSI---VTTVMQKrdvNGRLV 276
XP_002642224 242 KHVVRCYSRLSDNPsltldarvaqggagqnvkvRAQQALKQCLPD---QLK------DLTFKNCLKEDPSTMNWLRQLLT 312
EPR79231     212 TPALQCLRKILDIK-------------------QVKRALKSEIPP---FLK------DLQIKELLRNDANMLSVYDEIid 263
EIJ89296     215 ELTIKIYTKLCDMP-------------------NAKIAFNKNRPH---MLY------TESIREIVKSNPAVKAAYDEFLA 266
EOB12694     221 KSIIRVYLRLCDKQ-------------------QIRTNLSASKPD---NLS------NEEIKKVIQNDPECCKMYKEFLE 272
Q8SWP5       256 KVALRIYIRLCAKP-------------------HIRALLSSKKPD---GLF------TDEASLLIASDGECKALFKtftn 307 Encephalitozoon...
XP_009144001 254 NLIAGCYAKLSQKP-------------------RAREGLWRFPPV---MLL------NGTFASLFAEDPDAVNYRKQLIR 305
Q58FZ9       267 SLVTGCYVKLSQNS-------------------RARNGIRRYTPF---LLF------DGTFSRLYAEDPVAANNRIQLLQ 318 thale cress
XP_006843443 278 FHIIRCYVLLCTDT-------------------RGFNMLIDYLPE---PIT------NNSFQQITEEFPVIRRMLEQLLM 329
EDW24345     225 QHVLHIYTRLADNP-------------------ESLEMIQLHLPM---QLRngffcmDNVLS-----YDTVKSDLQTLNE 277
XP_653602    277 RYSLDCLNRLSTNP-------------------KATPQLHSVVTEykgLFK------DHLLEYIVSKEPSLKPKYDEFCR 331
XP_002642224 313 NL 314
EPR79231     264 il 265
EIJ89296     267 il 268
EOB12694     273 II 274
Q8SWP5       308 li 309 Encephalitozoon cuniculi
XP_009144001 306 NM 307
Q58FZ9       319 NL 320 thale cress
XP_006843443 330 NT 331
EDW24345     278 KV 279
XP_653602    332 NI 333
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