4QB7


Conserved Protein Domain Family
Mfa_like_1

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pfam13149: Mfa_like_1 
Fimbrillin-like
A family of putative fimbrillin proteins found by clustering human gut metagenomic sequences. Analysis of structural comparisons shows this family to be part of the FimbA (CL0450) superfamily of adhesin components or fimbrillins.
Statistics
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PSSM-Id: 463789
Aligned: 97 rows
Threshold Bit Score: 68.2148
Created: 25-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4QB7_A          24 TRGTettTSTLKAN-AGFGI---FA-YQTSSAGWNSEkgnttpnfXYNEHATW--------TSDSWGYT---NLRFWPID 87  Phocaeicola v...
WP_044163052    22 TRT-------TEMDkDNIGD---FK-VSTIKSSSTSF--------DFADDVMNgmavirgiNANTWSYS---PIKFYPDV 79  Bacteroides r...
CDD88427        52 TRVA---VESFTAG-SSFSV---WG-W-YLPKDAASE----------VFNATTvst----pdGSVWTYE---GLRYWKAD 105
WP_005856603    45 TRAV---VENNKEGmDNFTL---WG-W-VRESDGPK---------LFFDAVPVtps-------gnYGEK-----RFWAVG 95  Parabacteroides
EGF58342        42 TKA----IGDIDEN-NPLSAfyvFGgYGEDKNSVDFT--------NVFNNTKVn------aDGTAETIE------YWNDQ 96 
CDD88428        43 TRA----DVT-NADfKQFWV---YGdY---QNESSWV--------DVFNNVKVsga--svgSGAVWTPD---ETAYWQVD 98 
CDB04273        45 TRAT---DLT-TANlTDFQV---WGiMKKDNQIG-----------KPFVGTQVt------kAGGAWSYG---VPVYWEKG 97 
WP_013760278    50 TTAN------LTTKaPNFKV---WA-YLNATPAT-----------EYVKGVEIs------yQGTSWEYTnaaDLAYWPSE 102 Porphyromonas...
Q8ABW9          46 TRATpttNTNLKN--TDFDV---FA-FTADGTAFMGKnd----teFEHDGVKIv------yKNGKWDYDnasDLRYWPTE 109 Bacteroides t...
jgi:Odosp_1703  55 TRATpttPSNLTS--TDFDV---FA-FTADGTAFMGKvdt--eygHDGVNIVY--------KDNKWDYKnanDLRYWPSE 118
4QB7_A          88 DkKITFFAYA--------PyeskPEVGTDQKITLSGQNakga------ptiTFEVKTSNNWKDXIDLvtdchtAIQDQTN 153 Phocaeicola v...
WP_044163052    80 A-DVSFFAYS--------P----SGSVNVTKFEGQALKkati-----aytvPTSNADAKKAEDFLVA-------STNVVK 134 Bacteroides r...
CDD88427       106 K-TYSFYALY--------Ps--vTDLMANAATAAHYDEdg---------dlSVTAFDASKGYDLMAA------SALNISG 159
WP_005856603    96 R-PYGFYAVH--------Pe---KMKENNIATEVSCNDkgel-----rvtgFDSSEMGKGAVDLMTA------AKTDVVY 152 Parabacteroides
EGF58342        97 --YYQFVGYS-------------DGNQKLENATIKNGV-------------LYIPAYTVGEKDLIAS------NVKDHGT 142
CDD88428        99 K-TYNFGAYA--------D----GTSQLTTGISYNPTSk-----------tLTFSDYSAGANDLIAA------TSDDASW 148
CDB04273        98 Y-QYSFVAVA--------P----ADAFDMVEAPADYQDy-----------gKVKFNNGRGDTDLLWA------AKDKGLV 147
WP_013760278   103 --SLDFYAINpanngavtP----GITASAKTLTYTVPD--------------NGGASNAKQIDLMYAvd---kNRSKITR 159 Porphyromonas...
Q8ABW9         110 --ALDFYAFN--------P----GTVSEDMMAFYSWEAtkdvqkisytcmdEYGSGTTHANYDVMYA------MAKGQTK 169 Bacteroides t...
jgi:Odosp_1703 119 --ALDFYAFN--------P----GTVSEDMLAFYRWEAsgtsqk-isytciDEYGAGTHANYDVMYA------IAKGQTK 177
4QB7_A         154 ESNKg----tVQFKFSHVLTQIA-NIkVKPdvnlgtdTKIFVTGL----------KLdPGsttLYNKAVYKFDN-----D 213 Phocaeicola v...
WP_044163052   135 DDYDe----nVILTFKHALSLATfEAvNANdg---atFIVEKIEFsnmgnsstltAD-AA---TAATSTF-SWA-----Q 197 Bacteroides r...
CDD88427       160 SNTGk-----VAFTFGHLLARVEfVVkRNAaa---dgIEGFNPVIhs-------aKL-YG---MHKTADFLVSA-----A 215
WP_005856603   153 EGGGmm--apVLLAFKHELAQVKfTVcTGEkq---aeVSDI--------------RL-LG---VDYKGDL-LWTpe--eS 206 Parabacteroides
EGF58342       143 QKGT------VNMTLKHLLAKVKfTF--TStipvgyeVEISNLQF----------EAdKD---GAYTGAIGDAT-----G 196
CDD88428       149 DGSGdp--skVQLSFKHMLSKVKfTFkTDAaet--ytMKVSELKIsq------aiQTaTG---TMVDKVV---------G 206
CDB04273       148 TWEDnacpaaVDLTFNHMLSRVRfNF-VNGmdd-gslLTVKDVKI-------------TN---ACTEGTVQLIDan--aG 207
WP_013760278   160 ----------VPLYFKHALSQIVfKGqTISnt---leVEVEKITI-------------AN---VKGAGTFTLPTvttaaG 210 Porphyromonas...
Q8ABW9         170 DMNNg----iVKFNFKHILSQVVfKAkTQYdn---mqVDIDVIKI-------------HN---FKFAGAFTLPAaadgtG 226 Bacteroides t...
jgi:Odosp_1703 178 DSNNg----kVKFKFKHILSQVVfKAkTQYan---mrVDIRDIKI-------------HN---IRFSGVFTLPAaadgtG 234
4QB7_A         214 TWEA---ISPdaSyfsteQdLSDFL-------------------NKTt-TDqwgynkssinvsddqnaTAlFSdteaLYF 270 Phocaeicola v...
WP_044163052   198 PAQL---DQNktYavslpEaGISIL-------------------PNG--NG-----------------KL-TPekegLMI 235 Bacteroides r...
CDD88427       216 DLTD---KEAi------sA-GWAIStdesdrttknepfavlseeISV--NAdg--------------tTL-ID----ALL 264
WP_005856603   207 TWQN---RINctEegtpfVrSESVR-------------------IEA---G-----------------SS-VTvldsVLL 243 Parabacteroides
EGF58342       197 QWEI---GTPsaDktysfNiTNPVK-------------------INA--TG-----------------DE-TAvsdeFYV 234
CDD88428       207 TWLG----ENtgEysfadIdDYATA-------------------EGQa-ES-----------------EV-------KYV 238
CDB04273       208 KLVW---EPSgdAallfnDaPETAF-------------------AQSt-TC-----------------TT-GH----KYM 242
WP_013760278   211 STAGtwtLSGeaDqkytnAtNTTVV-------------------KDAt-AQ-----------------EL-SPadgaYLI 252 Porphyromonas...
Q8ABW9         227 SWSS---SDLafPhaftvVkNANIT-------------------VNSntEA-----------------TD-ITtntpMLN 266 Bacteroides t...
jgi:Odosp_1703 235 SWSS---PDLtfPhaftvVkDKSIT-------------------VEGntTA-----------------TD-IStsspMLN 274
4QB7_A         271 IPVNnkn------------gtTNAGDLKLKI----NYDIvtkvtdtsNLTS-TITNKevs-----lpkNT--FKKGTKHT 326 Phocaeicola v...
WP_044163052   236 LPQEi----------------IGTTRLIITFr---AIDGey----kdIYESgSVKEFeiptnvaapalFT--FAMNTRYH 290 Bacteroides r...
CDD88427       265 FPQD------------------LTIEYYFEVtyssASDRe-------PCTS-TVPLVsl-------plTT--WEAGKHYR 309
WP_005856603   244 LPQPv----------------TEHVAVTFKY----AYAGk-------PLSE-AKEAMvyld---vaqtTE--WIKSSTYH 290 Parabacteroides
EGF58342       235 IPQN-----------------PSLTITFTGIlkddNGTEit----rkDFTS-TMSAT---------------WISNNAYN 277
CDD88428       239 IPQEn----------------TNSIAVSFRVtv-tDGGGys-----kEGTF-TGTMAi---------aESnkWDAGLAYN 286
CDB04273       243 IPAD------------------KVYNVTFVVe---RVHNgv----vdTYTH-TVALT------------KmqMESGKSYQ 284
WP_013760278   253 LPQTatkwtttpttavtiataDTNHECYLALsvkiKQSG--------VYLVgDATSYgtvyv--pfggED--WAPSKKYI 320 Porphyromonas...
Q8ABW9         267 IPQEltawkvsetatkskleaDNAKQCYLEIackiRQSG--------AYLLgSASEYktiy---vpfgDT--WEQGKRHI 333 Bacteroides t...
jgi:Odosp_1703 275 IPQEltawtvsg-asktkkgaDDAKQCYLEIsckiQQSG--------VYLLgSASEYkiiy---vpfgVI--WEPGKRHI 340
4QB7_A         327 YVLTIKx-------nAIKITV-EDNXEGW 347 Phocaeicola vulgatus ATCC 8482
WP_044163052   291 FKFTFDa--------LNDIKF-EVKMSPW 310 Bacteroides reticulotermitis
CDD88427       310 YTFTVSd-------eDRILFD-TPTVNAW 330
WP_005856603   291 YKITLPa-------gDADITV-KVSVGDW 311 Parabacteroides
EGF58342       278 YTAELTqekf-dlndNNIIKF-EPNVKPW 304
CDD88428       287 YTVTINpdkvddtlkPILFDV--TTVEEW 313
CDB04273       285 FKAEFTsqninpdgaLCPIVF-TADVNGW 312
WP_013760278   321 YTLKFGggydqdgkpILQPILyDCTVEDW 349 Porphyromonas asaccharolytica
Q8ABW9         334 YTLIFGggyddqgeaVLNPIQfDAETTGW 362 Bacteroides thetaiotaomicron
jgi:Odosp_1703 341 YTLIFGggytdqgkaVLNPIQfDAETTGW 369
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