6CC4


Conserved Protein Domain Family
MurJ

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COG0728: MurJ 
Lipid II flippase MurJ/MviN (peptidoglycan biosynthesis) [Cell wall/membrane/envelope biogenesis]
Statistics
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PSSM-Id: 440492
Aligned: 841 rows
Threshold Bit Score: 141.826
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6CC4_A       107 LKS--LAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVAFKLPNLLRRIFaEGAFSQAFVPILAE-YksK--QgED 181
WP_096550409   5 LKI--VGAVAIINIAARIFGFFREMAVGYQYGFSYAADSIFTAYMVPNFLYLVV-GGAFTTAVISLYNR-KttN--Qs-- 76 
WP_121616385   6 LKL--LGAVTIINILAKLMGFAREVIIGYQYGTSYQADSIITAITIPNFLYLVI-GGAVTTAFISVYSKlKgkE--Kn-- 78 
WP_123041891   7 VSG--AVILFVGNLLSSFLGLFREVLLAAQYGADVDMDSYLFANAVPSILLAFV-TSVFLTGFIPLFIK-ArvH--QsAE 80 
WP_006927201   9 FKS--IGYVTIGTILGKISGFLKHYLVVYSFGLTEYADAFFVANIIPEMLVNILiSGLLAGAFIPVASE-VlaI--EgKK 83 
WP_096467363  14 FGGmgTNGVALINLLLAIVAFGKDLMQATYFGTSPSADALTLAFFIPDTVGNNLlASAIGVACVPMFCK-LlvQ--ReTK 90 
WP_024362453   5 IKI--VGAVAIINIVARVFGFLREMIIGFQYGSSHIADSIFTAYTIPNFLYLVV-GGAFTTAVISIYNR-EttD--Ra-- 76 
WP_042384699   7 FQI--IGVVTVINILSRFFGFVREVMIGYHFGTSSLADSVVLAYTIPNFLYLVL-GGAVTTAYISIFSK-ManDieKq-- 80 
WP_067212183   5 MKI--IGAVAIINIVARLFGFAREMAISNQYGASATADAIITAYTIPNFIYLVV-GGALTTAFISVYHS-TrtD--Ka-- 76 
WP_038564256   2 INS--LKNLLYSNSIGKLLGFLREILLAYIFGTGSVIDFFRLCNSLVLTPLNLFvGNSLQQVFIPNYKK----K-----D 70 
6CC4_A       182 ATRVFVSYVSGLLTLALAVVTVAGMLAAPWVI-MVTAP-----GFadTADKFALTSQLLKITFPYILLISLASLVGAILN 255
WP_096550409  77 ---EFVKQSFTIVLTSGIVMTAVLLLFTDPII-KMLFEnn--eDI--APDAIELTKHLFYWMMPSSIFLILASYYSGLLN 148
WP_121616385  79 ---DFAQTIFTLLSSTAVIITLFFMLFPHFWI-QLFFS-----GM--SEEAMDLTSKLFVWTAPATLFLLIGITLSGLHN 147
WP_123041891  81 EASLMFSNTVNWFIVIILGIIGICYAFSSGLS-AI---------FadNPAVHEKVEHLLWILLPGMLFFGLSYAQSTVLN 150
WP_006927201  84 RFSDFISSLFIFVGILSLIFSMLLFFIPDLIA-KVLAP-----GY--TVNQLKIVSNLLRYFSPGIIFLGLAAILAGILQ 155
WP_096467363  91 RLQLLFIRVTVYTFLFSGGCFLLFYLFQNPLL-HWLGQ-----GF--TPEVYSQCKHLLMILLPTMVLFPLWMIGSAALQ 162
WP_024362453  77 ---LFVKQSFTIVLLTVSIMTIILLAFTNPIM-DMFNQgknkdDY--SQSDLDLLKNLYFWMMPSSILLVLSSWYSGLLN 150
WP_042384699  81 ---RFHNTVFTYMLIFLLLITAGLMVFAKPIV-AFFFS-----GL--AGSQLMMTSQLFMITAPSALFLVFSMWFSGILN 149
WP_067212183  77 ---LFVRKSFTTVLVAAVAITAILMIFTDSIL-HLFFK-----DM--TAEKFALTRTLYLWMMPSSIILVLSTWMSGVMN 145
WP_038564256  71 NKIQFVLSISIMILILSIILCLFLFIFAGEIIkSFLGA-----GY--TDGEVHIAINFLKIFTLGIPFYVLNWMIIYTLN 143
6CC4_A       256 TWNRFSIPAFAPTLLNISMIGfAL-FA-A---PY--FnpPVLALAWAVTVGGVL---QLVYQL-PHLKKIG---ML-V-L 319
WP_096550409 149 VHNKFHLSSFSILIYNVAFLViAV-AL-S---FV--I--GPIAYGISAFASSII---MIYFLI-VGYRKLDs--SHpI-G 212
WP_121616385 148 VHENYRLSTFSTFLFNGIYLViGV-GL-T---PW--L--MEYSYALGATIGAFS---MFGLLL-FYIWKLR---LMpI-Q 210
WP_123041891 151 SLNHFTLPALLSVLNNIVVIVfMV-LF-H---QS--M--GIYSVAVGYVLGNVL---QVVVQI-PVVRKKG---VR-Y-R 212
WP_006927201 156 SLEDFRIVSFGLLIYNVTFIGsLL-IF-S---PR--Y--HVLSAGLGISLGAFF---WFGSHF-LFTYRM----MK-W-K 216
WP_096467363 163 AKGMYVRSAFTPVVFNSIYLGaIAcLFvQhvsPd----rGAIVVAVGIFIGVCS---MVMLVW-LGLHRKGddqVRwY-R 233
WP_024362453 151 VNEKFHLSSFAILIYNAIFLViAV-GL-S---YIpgI--GPLGYGISALASAAI---MVYFLI-IGYRKLD---SHkV-G 215
WP_042384699 150 AQDQFYGAAVAALVNNGMFVLlVV-LL-Y---PF--C--GIYAYGWGAVASAAV---MLLILF-VQLRKNN---LHrF-Q 212
WP_067212183 146 VNGKFNLSSLAVLLYNASFVGiAV-VL-T---SY--F--GPESYGIGALVGALL---MGVFLY-VGLRKSK---LYsL-K 208
WP_038564256 144 SNKNFKENGRNILNFNLVLIGvTA-IF-L----L--Fp-NIYLIPASFVIANIFiviQLCYKYsKKIKR-A---LRsLkK 210
6CC4_A       320 -------PRINFHDAG--AMRVVKQMGPAILGVSVSQISLIINTIFASFL--ASGSVSWMYYADRLMEFPSGVLGVALGT 388
WP_096550409 213 -------ISFK-RDAT--TKDLWIMVVPIMIGGGTIQIYAMLQRFFAQLLgfGESAISVVNYASRLTQFPQTILITAVTT 282
WP_121616385 211 -------FKI-IKMPE--VGRFSRLAIPLVLGGATIQFYLIIQRIFAADL--NNGVIASLNYASKMTQFPQAVLMASVTT 278
WP_123041891 213 -------FYIRIKDEY--LRKLLTMSLPIITLVLIDQTMVFASRYFSAYL--DAGSASAINYANRILMLPVTLFGTAMVS 281
WP_006927201 217 -------PAFSAVVAY--LKKTAKLAVPSLLIITISNMVLLVEKNFASRF--VAGTISELNLAFRLSHLFLIVLILPLST 285
WP_096467363 234 ydkniwqLAFcIQ-DD--FIRVLRTFVPYLMILLSTQLVLAVERNIASKM--ESGTIAGLNYAFRLAQFPNWVFVAALTT 308
WP_024362453 216 -------FSL-ERNVS--SKQLWIMVLPIMLGGATIQLYALLQRVFAGML--SEGAVAAVNYSSKLMQFPQAILITAVTT 283
WP_042384699 213 -------FQL-VTTEPeyIARMLKIAVPVLFGGATLQLYIFIQRMFASQL--EAGYVAALNYALKFVQLPQVILMTSVTT 282
WP_067212183 209 -------PSF-AMSVD--TKRLWVIALPILFGGASLQFYAVIHRIVAGEF--GDGTIAAVNYASKLTGFPQAIMMTAVTT 276
WP_038564256 211 -------LTFALVfSEn--RSFLSLWMPLLVYSLFMQIYILVERWLLSK---EKGLIAASEYAKVIIDTPIFLLTLPLAT 278
6CC4_A       389 ILLPSLSKSFASGNHDEYNRLMDWGLRLCFLLALPSAVALGILSGPLTVSLFQYgkFTAFDALMTQRALIAYSVGLIGLI 468
WP_096550409 283 VIYPILSRKEAEDDHESIKSLYSRGLRYLVLLMIPVSIFAYFYAENIIQVIFEYgnFTKEGTKLTTPVMQIFVLSMFFLA 362
WP_121616385 279 IIYPMLAKAAGEGDISRIEEAYIKGFRMLTLILLPASIYIFIYAKDIITFIFEYgsFNEDSTNATYPLLQIFSLSIFSLA 358
WP_123041891 282 ATYPSAVQMWTENKRKEYNTIVSTGIKSLLLILIPIFFFCMLFATNIVQALLERgaFDEKATRMTSTVFLVLSAAIVIMP 361
WP_006927201 286 VLLPRMTKYFSQKQYDKIKATIQSVMQIITAILILFFIFFVYNAHFVTKMTYFFlhVDSKNLLLISEYALWYAVSFIGLF 365
WP_096467363 309 VLLPSISKAVGENNLKLASAAMNSAVKMTLIITVPVTVIFFLGRIPLISLLFQHgsFDQHSVQITSNILAGYSLAIVSQA 388
WP_024362453 284 VIYPILSQKEANNDLVSIKSLYSKGLHYLLLLLVPVTIYSYFYAENLIQVIFQYgkFNAYSTAITAPVLAIFVLSMYFLA 363
WP_042384699 283 VIYPMLAKKTAEKDYGGISSIFFRGLKSLFMIIVPVSVFVYFYAEEMVKLIFEYgsFTAQSTKMTAMMLKIFIIGMFAQA 362
WP_067212183 277 VIYPLLSKKEGEGDMDTIRALYKKGMLYLVALLVPATMIAYFFADPLVRLVFGYgeMTEKDILLTVSLFRVFTLSMFFLA 356
WP_038564256 279 IGLTYFNR----NEr-SITNKIVSMLFFVTLISISLTSMLFMNQESIIRMLYYRgnFDEESLTLVLSILKFYIIGFAFFS 353
6CC4_A       469 VVKVLAPGFYSRQDIKTPVKIAIVTLI-LTQLMNLAFIGPLKHA-GLSLSIGLAA--CLNASLLYWQLRK-QKIfTPQ-- 541
WP_096550409 363 ANTYITRFYYAKGDSIAPVIFSIVNVFiVNIAVMYLLADSTGVN-SIAWGTLISS--VVNTVLLIIYAHF-RYGlKIG-- 436
WP_121616385 359 LNTYVTRFFYALEKTILPILLNVISIFgINIFVIVLYLDDLGAK-AIALGTVVST--IVNMLLLIAFAQI-RLKlVIC-- 432
WP_123041891 362 VRDFFNKLFFSRGQFKTPITYSLIYTA-GFVTSCFILVPLIGYI-GIAVSTIGSL--TVSFAYLVLTYKR-LN------- 429
WP_006927201 366 YYMFLLRVFYSMQQIWEIVKANLIGMA-FYLIFLSILIPKLEVY-AFPIAYSIYA--IVTTIYLALYLNF-KL--FPR-- 436
WP_096467363 389 LSAVGMRYFMAVERMIAPTIISFIALL-VNVVCDQLLTFHIGAA-GLGYGAACGA--LVNASGIMLFAYR-DL------- 456
WP_024362453 364 ANTYITRFYYAKGDSMAPVIFSLINVFgVNIAVIMLMVENYGAE-AIAWGTLISS--ITNFMMLIFYAIP-KYDlKMGif 439
WP_042384699 363 ANLFITRFFYAMEKSFVPVATGMISVFgVNILIIKLFIGKYGAD-AVAWGTTVSA--IVQFLMLAIASVV-QLRlQPE-- 436
WP_067212183 357 ANTYITRFYYAKANSMVPVIFSLISVFaINLGVIYLMIDSHGAS-AIAYGTVISA--AVNFVMLAIYARV-KWKl----- 427
WP_038564256 354 VNTFLYRIYNAELRNKELSLVIISAHI-IAFIFMIVCYQ-LGYKvNIIVGYSFIIlnAIQFFILI---CRiRLN-I---- 423
6CC4_A       542 -PG----WM-AFL-LR-LVVAVLVM---SGVLLGM-LHIMPewslgTMPwrLLR-LMA-VVLAGIAAYFAA---LA-VLG 603
WP_096550409 437 -NG----KL-KDS-FK-LSIPLILI---GCITYLS-SKYLVfd------ykWVT-FIT-----GLVIFSVStigLFmLFR 492
WP_121616385 433 --S-------LRY-IL-KLVVFTLI---TIVAIWL-VSIVPsh------hvLLT-LLF-----GGIVMVLMig-----gG 480
WP_123041891 430 -KGetigIAfSYF-MK-IVLSAGVS---SGLAYGLyWEVLrdl-vpGKLgdLIV-TVL-AIGAGFALYFVL---VK-MLK 496
WP_006927201 437 -SN----ILg---qNKiFYVASIFY---VLIA--InVKIFw-----GakngVLEdILFsLIFLSFYIYF--------LLR 490
WP_096467363 457 -RKy----------MKv-----------GA----------------E--------------------Y------------ 466
WP_024362453 440 sKE-------LQF-FR-AVPPMIVI---AVVMYYS-SHYLVfe------ykWLT-FIV-----GLAIFIAVfvgSYlVFG 494
WP_042384699 437 -KE-------AQW-LR-LILYALCA---TIAAAII-HKYIDfh------hhIAN-IFI-----GGLTFVLVsllLLkSFR 490
WP_067212183     --------------------------------------------------------------------------------    
WP_038564256 424 -KS----VV-RSTfFKkLLLINIIYvliGFIIFnL-----------Nen-qFIHyLLI-ILWITVFLYs-----AY-ILK 478
6CC4_A       604 FK-VKEFAR 611
WP_096550409 493 IKeVEDYIN 501
WP_121616385 481 LKsVK---- 485
WP_123041891 497 VEeVNFVWN 505
WP_006927201 491 ----KKVFN 495
WP_096467363 467 ----EPLpn 471
WP_024362453 495 IKeVKEFTD 503
WP_042384699 491 LMsFQrlpm 499
WP_067212183     ---------    
WP_038564256 479 ----KEV-D 482
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