Conserved Protein Domain Family
trehalose_treC

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TIGR02403: trehalose_treC 
alpha,alpha-phosphotrehalase
Trehalose is a glucose disaccharide that serves in many biological systems as a compatible solute for protection against hyperosmotic and thermal stress. This family describes trehalose-6-phosphate hydrolase, product of the treC (or treA) gene, which is often found together with a trehalose uptake transporter and a trehalose operon repressor.
Statistics
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PSSM-Id: 274115
Aligned: 12 rows
Threshold Bit Score: 816.581
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P39795           8 WWKKAVVYQIYPKSFNDTTGNGVGDLNGIIEKLDYLKTLQVDVLWLTPIYDSPQHDNGYDIRDYYSIYPEYGTMEDFERL 87  Bacillus subt...
CMCP6:VV1_0288  10 WWKTATIYQIYPKSFCDSGAKGTGDIQGIISKLEYLKHLGIDAIWLTPVYQSPMVDNGYDISDYYRINPQFGTMADFDEL 89  Vibrio vulnif...
P28904           7 WWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQHLDYLHKLGVDAIWLTPFYVSPQVDNGYDVANYTAIDPTYGTLDDFDEL 86  Escherichia c...
AAP07649         3 DWHKSVVYQIYPKSFNSYYNRETGDIKGVTEKLDYLKELGVDYIWLTPIYQSPQNDNGYDVSDYYSIDPSYGTMEEFEEL 82  Bacillus cere...
AAN06917        18 DWQRSVIYQIYPKSFYSHGGQATGDLLGVVDKLDYLHWLGVDYLWLTPFLRSPQRDNGYDISDYYAIDPSYGTMADCELL 97  Pseudomonas f...
AAS08576         3 NLGNKVIYQIYPKSFYDSNNDGIGDLRGIIQKIDYIKKLNVDFIWFNPFFVSPQNDNGYDIADYKKIDPRFGTMADFEEL 82  Lactobacillus...
CAD62920         2 KLSEQVIYQIYPKSFYDSNGDGVGDLRGVIEKIDYLKKLNIDMIWFNPFFVSPQNDNGYDIADYYHIDPMFGTMADFEEL 81  Lactobacillus...
AAL98602         3 IDKKKVVYQIYPKSYKDTTGNGVGDLRGIIDKLPYLQELGIDMIWLNPFYLSPQRDNGYDVSDYTAVNPDFGTMADFENL 82  Streptococcus...
AAP55645         5 NFQEAIVYEIHPQSFYDSNHDGVGDLQGIIQKLDYLAMLGVNYLWLNPIYVSPQKDNGYDVSDYKNINPLFGTMNDFEML 84  Spiroplasma c...
AAT27549         4 VNSKKIVYQIYPSSFKDSKGTGRGDIKGIIEKLDYIKDLGVDYLWLSPIFKSPLKDNGYDVSDYLSINTLFGDLEDLKSL 83  Mycoplasma mo...
AAT75857         1 -mRNEVIYQIFPLTFSDGKKKGKGNIKGIINKLDYLKSLGITRIWISPFTKSPFKDSGYDVSDYCGINEEFGTMEEVEIL 79  Mesoplasma fl...
WP_010990838     3 KFAQKTIYQVYPKSFFDTTGDGTGDIPGITAKLDYLQELGIEMIWINPFYPSPQNDNGYDISDYTAVDPLFGTMNDVTTL 82  Listeria innocua
P39795          88 VSEAHKRDLKVVMDLVVNHTSTEHKWFREAISSiDSPYRDFYIWKKPQenGSVPTNWESKFGGSAWELDEASGQYYLHLF 167 Bacillus subt...
CMCP6:VV1_0288  90 LEKAHQLGIRLIMDIVVNHTSTEHAWFQSALGNkNSPYRDYYIWKDPVe-GKVPNNWQSKFGGSAWALDEQTGQYYLHLF 168 Vibrio vulnif...
P28904          87 VTQAKSRGIRIILDMVFNHTSTQHAWFREAL-NkESPYRQFYIWRDGEp-ETPPNNWRSKFGGSAWRWHAESEQYYLHLF 164 Escherichia c...
AAP07649        83 LAEAKVRNIEIMLDIVVNHSSTEHKWFKEAKEDkNSPYRNYYIWRDEK------NNWQSKFGGSAWKYDEKTEQYYLHLF 156 Bacillus cere...
AAN06917        98 ITEASKRGIKLMLDIVVNHTSIEHPWFQAARSSlDNPYRDFYIWRDQP------NNWESKFGGSAWEYEAQTGQYYLHLF 171 Pseudomonas f...
AAS08576        83 VAKLKDINVNVMLDMVLNHCSTEHEWFKKALAG-DKKYQKFFYLRKGKd-GKLPNNWQSKFGGPAWSKFGDTDYYYLHLY 160 Lactobacillus...
CAD62920        82 VAKLKANGIGVMLDMVLNHTSTEHEWFQKALAG-DEKYQKFYYLRPPKadGSLPTNWESKFGGPAWAPFGDTGLYYLHLY 160 Lactobacillus...
AAL98602        83 VKAAKEHQIELMLDMVLNHCSTDHEWFQKALAG-DPYYQDFFILR------DQPTDWVSKFGGNAWAPFGDTGKYYLHLF 155 Streptococcus...
AAP55645        85 VTEAGKRNIYIMMDMIFNHCSTEHEWFQKAQTGnLDYLQRFFFLPGDK--AKCPNNWQSKFGGSVWEYHDELKMFYLHLF 162 Spiroplasma c...
AAT27549        84 IKKAKEKNLKVMLDMVFNHTSTEHEWFKKWINN-DPEYKDFYISKKSV--GKPPTNWVSKFGGSAWKEYK-KNNWYLHLF 159 Mycoplasma mo...
AAT75857        80 ISEAKKRDLTIVLDIVFNHTSDQHEWFKKALAG-DEKYMNYYIFKDPVd-GKEPTNWKSKMGGLSWEFVPNLNKYYLHLF 157 Mesoplasma fl...
WP_010990838    83 ISEAKKRNIGIMIDLVLNHTSTEHPWFKKALAG-DPFYRDFYYFRPAKadGSPPTNWESKFGGSAWQKLPNSSEYYLHLY 161 Listeria innocua
P39795         168 DVTQADLNWENEEVRKHVYDMMHFWFEKGIDGFRLDVINLISKDQRFPNAEe----GDGRSFYTDGPRVHEFLHEMNEKV 243 Bacillus subt...
CMCP6:VV1_0288 169 AKEQADLNWENPTVREEVKNVIRFWAEKGVDGFRLDVINLISKQQDFCDDEi----GDGRRFYTDGPRVHDYLQEISQAV 244 Vibrio vulnif...
P28904         165 APEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDPRFPEDLd----GDGRRFYTDGPRAHEFLHEMNRDV 240 Escherichia c...
AAP07649       157 DETQADLNWENEKLREEVYDMMRFWLDKGVTGFRLDVINLISKDQCFLNDEgstatSDGRKYYTDGPRVHEYLQEMNRNV 236 Bacillus cere...
AAN06917       172 DHTQADLNWDNPQVRAEVFKMMRFWRDKGVGGFRLDVINLISKPADFPDDH-----TDGRRFYTDGPNVHRYLQEMHREV 246 Pseudomonas f...
AAS08576       161 DPTQADLDWHNPEVRAALIDVINFWRSKGVHGFRFDVINVTGKDTVLVDSTd---pVQEKSLYTDTPVVQQYLKELNAKS 237 Lactobacillus...
CAD62920       161 DPTQADLDWHNPAVRQACAAVVNFWRQKGVQGFRFDVINVTGKAEKLVDAPk---gVPSKTLYTDTPVVHDYLKELNAAS 237 Lactobacillus...
AAL98602       156 DVTQADLNWRNPHVREELAKVVNFWRDKGVKGFRFDVINLIGKDEELADCPv---nD-GKPAYTDRPITHTYLHDLNQAS 231 Streptococcus...
AAP55645       163 DKTQVDLNWKNESLRQHIYQIVNYWLQKGVRGLRFDVINLIGKPNIFENDLt----GDGRKYYTDTPQVHTYLQEMAQNT 238 Spiroplasma c...
AAT27549       160 DETQADLNWENEKVKEKIKEVIRFYINLGVKGFRFDVINLISKSNFNEDE------TDGRKFYTDGKKVEDYLQELRNEF 233 Mycoplasma mo...
AAT75857       158 TKEQPDLNWENPEVRNELINILKFWKDKGISGFRLDVCNLYSKPTLFENDEi----GDGRRFYTDGVKVEEYFNLMHNEV 233 Mesoplasma fl...
WP_010990838   162 DVTQADLDWANKNVREALFDVVNFWIDKGVEGFRLDVLNVIAKPKFLEDDFe---gD-GRRFYTDGPGIHAYLKELNERT 237 Listeria innocua
P39795         244 FS-HYDSMTVGEMSSTTVDHCIRYTNPDNKELDMTFSFHHLKVDYPNGEKWALAPFDFLKLKEILSDWQTGMHaGGGWNA 322 Bacillus subt...
CMCP6:VV1_0288 245 FQ-KYGSVTVGEMSSTTLEHCQQYSSLDGKELSMVFNFHHLKVDYSNGEKWTKAPFDFLQLKQIFNHWQTGLN-GKGWGA 322 Vibrio vulnif...
P28904         241 FT-PRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFNFHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMH-NVAWNA 318 Escherichia c...
AAP07649       237 FA-GKDVITVGEMSSTTIDNCIKYSNPERNELSMTFSFHHLKVDYPNGDKWTKADFDFIKLKEIMSSWQIEMQkGGGWNA 315 Bacillus cere...
AAN06917       247 FE-GFDLINVGEMSSTSLEHCVRYSCPASRELSMTFNFHHLKVDYPNLQKWVRADFDFLELKRILSDWQVGMQaGDGWNA 325 Pseudomonas f...
AAS08576       238 FGqDPESVTVGEMSSTTIENSIAYTRPQDHELSMVFTFHHLKVDYKNGEKWSKMSFDFKKLKDIMLTWNSKIDqGGGWQA 317 Lactobacillus...
CAD62920       238 FGqDVNSVTVGEMSSTTVANSVGYTNPANHELSMVFNFHHLKTDYVDGRKWSRMAFDFPRLKQLLDSWASGMAaGGGWQA 317 Lactobacillus...
AAL98602       232 FGqDDSFMTVGEMSATTIDNCLLYTAPEREELSMAFNFHHLKVDYENGQKWTIMAFDFAALRDLFHAWGEGMSqGNGWNA 311 Streptococcus...
AAP55645       239 YLkTNDIITVGELSSTSIKQAILYTKPVSQELNMAFTFHHLKIDYLNNEKWKLAPYDPAKLVAKIKEWQIPVQaAGGWLA 318 Spiroplasma c...
AAT27549       234 Pk-EGDFLTVGELSSTTMQKASIYSNLDKKRLDSAFTFHHLKIDYDEKGKFIYKKPDIKKLNEIFDTSFTETQkLNGYLA 312 Mycoplasma mo...
AAT75857       234 FGtDNEIFTVGEVSSTTKEKSAKYAKVENKELDSVFTFLHLKVDYENNDKWTNVKPDLNLFWKLQKEWQEYYQlENSTLA 313 Mesoplasma fl...
WP_010990838   238 FG-DKPIVTVGEMSSTDIDNCIRYSDPKEKELSMVFHFHHLKVDYPDGEKWRLADVNFANLKSIFHTWQVAMSeENGWDA 316 Listeria innocua
P39795         323 LFWCNHDQPRVVSRYG-DDGAYRVKSAKMLATAIHMMQGTPYIYQGEELGMTNPKFTDISSYRDVESLNMYHAFK-EKGM 400 Bacillus subt...
CMCP6:VV1_0288 323 LFWCNHDQPRIVSRLG-NDQVYRVESAKMLAASVHMMQGTPYVYQGEEIGMTNPGYTAIEQYRDVESTNMYQIMVeQQGI 401 Vibrio vulnif...
P28904         319 LFWCNHDQPRIVSRFG-DEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESLNMFAELR-NDGR 396 Escherichia c...
AAP07649       316 LFWCNHDQPRIVSRFG-DDGKYRNESAKMLATAMHMLQGTPYIYQGEEIGMTNPKFESIEQYRDVESLNIYDIKL-KEGL 393 Bacillus cere...
AAN06917       326 LFWCNHDQPRVVSRFG-DDGEYREPSAKMLATALHFLQGTPFVYQGEELGMTNPGFEHIEQYRDVETLNIYRLKR-NAGV 403 Pseudomonas f...
AAS08576       318 LFWNNHDQPWALNRFG-DTGKYHDKSAEMLALALHLLRGTPYIYMGEEIGMMDPHYTSMKDYVDIEALNAYDALI-AKGM 395 Lactobacillus...
CAD62920       318 LFWNNHDQPRALNRFG-DAGRYRVKSAEMLATVIHLLRGTPFIYMGEELGMTDPDYDNMADYVDIEALNAYRALI-RSGY 395 Lactobacillus...
AAL98602       312 LFYNNHDQPRALNRFV-DVTHFRNEGATMLAASIHLSRGTPYIYMGEEIGMLDPDFDSMDDYVDVESLNAYSSLL-VSGK 389 Streptococcus...
AAP55645       319 NFLNNHDQPRALSRFG-DPENYRFESATALAAVVLLLRGTPYLYQGEEFGMENNNYTKIEQLKDVESINYYHILQ-KEGE 396 Spiroplasma c...
AAT27549       313 VFLNNHDQPRAVSRF--IDEEFHNVGAKMLGMLTLSLPGDTYIYQGEEIGMKNPNFENKEDYKDVETLNYFKELK--LEK 388 Mycoplasma mo...
AAT75857       314 LFMNNHDQPRAVSRFGnVDKYWYESATSIFAFTSLMR-GVPFIYQGEEIGMTNLTFNNLNEFKDVESIGNANDLL--KIK 390 Mesoplasma fl...
WP_010990838   317 LFWNNHDQPRALGRFAsDRPEHYYHSATLLGATIHFMRGTPFVYMGEEIGMMNPKFPTIDDYVDIETLNHFDILH-KNGL 395 Listeria innocua
P39795         401 ADQDITAILQAKSRDNSRTPVQWDATENGGFT-TGTPWIPVAGNYREINAEAALRDQNSVFYHYQKLIQIRKMYDIVTEG 479 Bacillus subt...
CMCP6:VV1_0288 402 DHDEMMAILAQKSRDNSRTPMQWSEEKHAGFT-QGEPWLAVASNYPKINAEAAVADLNSVFYFYKRLIELRKEEPVITQG 480 Vibrio vulnif...
P28904         397 DADELLAILASKSRDNSRTPMQWSNGDNAGFT-AGEPWIGLGDNYQQINVEAALADDSSVFYTYQKLIALRKQEAILTWG 475 Escherichia c...
AAP07649       394 SKEEIIGILKQKSRDNSRTPMQWNEEMNSGFT-TSTPWISAAENFKEINVEKALEDKESVFYHYKKLIELRKTYDVITEG 472 Bacillus cere...
AAN06917       404 SEANAMASIMQKSRDNGRTPMQWNAGPNAGFS-RAEPWIGVPANAAFINVEQQQQDPTSVLHYYRQLIALRRSEALIQDG 482 Pseudomonas f...
AAS08576       396 NKKEAFEIVQSKARDNSRVPMHWDNSKYAGFS-ESKPWLMP-TDQDKVNGEKELR-EGEIFNFYQKLIKLRKSEELISAG 472 Lactobacillus...
CAD62920       396 SHHDAFTIVKTKARDNSRTPMQWDDSAKAGFT-TGKPWLTP-TNQATINVAHELA-SGEIFDYYQRLIKLRKTMPIVADG 472 Lactobacillus...
AAL98602       390 SAKEAFAIIKAKSRDNARTPMQWDASEHAGFT-TGKPWLEVGKSYRDINVETEK--EGRIFPFYQRLIALRKELPIIAEG 466 Streptococcus...
AAP55645       397 QPNAILEVLSARSRDNARTPMQWNNQQFAGFS-THKPWIDVNTNYLKINWEKDYHSSQSIFKAYQMLIQLRKNNLAFSYG 475 Spiroplasma c...
AAT27549       389 AN----DGIKQKSRDNSRTPMQWNSEKNSGFS-MVKPWINVAPSYKEINVEKQENDPNSILSFYRKMVKVSKSDKVFANG 463 Mycoplasma mo...
AAT75857       391 SEEEVLDILRIKSRDNARSVMQWNDEFNAGFSeKENIDLFVNKNYKTINVKNQLNDDKSVLNFYKKVINLRLNEEVFNDG 470 Mesoplasma fl...
WP_010990838   396 SEQEVMTIIKERSRDNSRTPMQWDSSNNAGFT-TGTPWLKVADNANEINVQKALSDKTSIFYFYQKLIALRKEYPVIQTG 474 Listeria innocua
P39795         480 TYEIIAKDDPNIFAYLRHGSN--EKLLVINNFYGTEAAFTLPDSLAPdewkAEVLLTN-DEAREGl-QNMTLRPYESIVY 555 Bacillus subt...
CMCP6:VV1_0288 481 DYQDLLPEHQSVFAYARTSAA--QQLVCINNYYGEEVECVLPLDLDMrkakCLLSNYQnQPSAMAs-HHQVLKPYETRIL 557 Vibrio vulnif...
P28904         476 NYQDLLPNSPVLWCYRREWKG--QTLLVIANLS----REIQPWQAGQmrgnWQLVMHNyEEASPQp-CAMNLRPFEAVWW 548 Escherichia c...
AAP07649       473 EYAILDKNDPKIWAYTRTTES--EVLLVINNFYGEEITYSVPAHVQLdgmkQEVLLSNyKDASKDi-AKLNLRPYESIVY 549 Bacillus cere...
AAN06917       483 VYRLLLPEHPHVWAYLREGQG--ERLLVVSHFYGGDCEVELPEGVLThdtkQRWVIGNyEAGEHRy-RRLRLRPYESFVL 559 Pseudomonas f...
AAS08576       473 HIKPLLMDHPQVMAYERYLDNsdEKLLVFANFYGKETKVEIPTEYIDr--dGEILIQNyDEEIVTlpSTLELKPYEALAI 550 Lactobacillus...
CAD62920       473 GYQSWRLDDPQVFGYWRTYRQ--QKLLVLNNFYGQSTTVTLPEEMVG----AQVLLSNyQDVNVT--AQLTMQPYQAVAL 544 Lactobacillus...
AAL98602       467 DYRAAFKDSQAVYAFERHLGD--QCLLVLNHFYADEVELELPLRYQH----GQVLISNyEKVSIC--EKVMLKPYQTLAI 538 Streptococcus...
AAP55645       476 EIEFVEID-PTILSFYRYYEK--NKFLVLINLS--DQTIMIPDNLLS----EKTIYNNySTFEKK------INPYQVIVF 540 Spiroplasma c...
AAT27549       464 NITFLPYKEN-LIQFTRTYKN--KTYYFIFSFSNK----KISLDSKS----NIIILYSnYEYEKN-----IIKPYQFIVG 527 Mycoplasma mo...
AAT75857       471 TISFFENQD---YAYCRKLKD--KEIIILTNWTTENKLIKLKLDSNN----WKIILNNyEDFSFD-----SLKPYQVIAI 536 Mesoplasma fl...
WP_010990838   475 DYTPYLTEEDSIIAYKRSNET--ASLLAIHYFGATKKKIQLPKEFSD----GKILLSNyDRKEIS--AEIELSPYETLTL 546 Listeria innocua
P39795         556 RL 557 Bacillus subtilis subsp. subtilis str. 168
CMCP6:VV1_0288 558 LI 559 Vibrio vulnificus CMCP6
P28904         549 LQ 550 Escherichia coli K-12
AAP07649       550 RY 551 Bacillus cereus ATCC 14579
AAN06917       560 HL 561 Pseudomonas fluorescens Q8r1-96
AAS08576       551 KI 552 Lactobacillus johnsonii NCC 533
CAD62920       545 LL 546 Lactobacillus plantarum WCFS1
AAL98602       539 LA 540 Streptococcus pyogenes MGAS8232
AAP55645       541 DY 542 Spiroplasma citri
AAT27549       528 EI 529 Mycoplasma mobile 163K
AAT75857       537 ER 538 Mesoplasma florum L1
WP_010990838   547 IQ 548 Listeria innocua
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