Conserved Protein Domain Family
MADS

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cl00109: MADS Superfamily (this model, PSSM-Id:412166 is obsolete and has been replaced by 469617)
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MADS: MCM1, Agamous, Deficiens, and SRF (serum response factor) box family of eukaryotic transcriptonal regulators. Binds DNA and exists as hetero and homo-dimers. Composed of 2 main subgroups: SRF-like/Type I and MEF2-like (myocyte enhancer factor 2)/ Type II. These subgroups differ mainly in position of the alpha 2 helix responsible for the dimerization interface; Important in homeotic regulation in plants and in immediate-early development in animals. Also found in fungi.
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Statistics
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Accession: cl00109
PSSM Id: 412166
Name: MADS
Created: 8-Feb-2008
Updated: 24-Nov-2020
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