?cl17068: AFD_class_I Superfamily (this model, PSSM-Id:418409 is obsolete and has been replaced by 473059)
Adenylate forming domain, Class I superfamily This family includes acyl- and aryl-CoA ligases, as well as the adenylation domain of nonribosomal peptide synthetases and firefly luciferases. The adenylate-forming enzymes catalyze an ATP-dependent two-step reaction to first activate a carboxylate substrate as an adenylate and then transfer the carboxylate to the pantetheine group of either coenzyme A or an acyl-carrier protein. The active site of the domain is located at the interface of a large N-terminal subdomain and a smaller C-terminal subdomain.
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Jiyao W et al.(2023). "The conserved domain database in 2023.",