Conserved Protein Domain Family
CDC39

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COG5103: CDC39 
Cell division control protein, negative regulator of transcription [Cell division and chromosome partitioning / Transcription]
Statistics
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PSSM-Id: 227434
Aligned: 3 rows
Threshold Bit Score: 1908.98
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
10383811    1 MLSATYRDLNTASNLETSKEK----------------QAAQIVIAQISLLFTTLNNDNFESVEREIRHILDRSSVDIYIK 64   baker's yeast
19074937      --------------------------------------------------------------------------------      Encephalitozoon c...
19114235    1 MKSQEQQTPETREKSSSTSESghpisldsktpppndsKIESIVKAQILFLLSTLREDQYDTKLEQIRQLINKNAPRVYHH 80   fission yeast
10383811   65 VWERLLTLSSRDILQAGKFLLQENLLHRLLLEFAKDLP-----KKSTDLIELLKERTFNNQ-------EFQKQ------- 125  baker's yeast
19074937      --------------------------------------------------------------------------------      Encephalitozoon c...
19114235   81 FLRRLIQGNSYRIFGTGKSSDGLATYKLLLDELKSLTKswvmaKRFSDAISGSDSEVFEDFdieafldHFQFSplertnl 160  fission yeast
10383811  126 -TGITLS-----------LFIDLFDKSANKDIIESLDRSSQINDFKTIKMN--HTNYLRN------FFLQTTPETLESNL 185  baker's yeast
19074937    1 --------------------------------------------------------MDEK------IYRQEIKDVLEKSD 18   Encephalitozoon c...
19114235  161 lIGLTTSvkptlakkasaLLKNTFQSLLNQLSDPTQQQSIDKNDLDLLREGlfTTDYDRIplikvpKFDAIIEKKLANSR 240  fission yeast
10383811  186 RDLLHSLEGESLNDLLALLLSEILS--PGSQNLQNDPTRSWLTPPMVLDATNRGNVIARSISSLQANQINWNRVFNLMST 263  baker's yeast
19074937   19 -------PREVDRSFMDDALQRIRR---RREVVPEEVARAILFMADFPDR-EWNLSAIVGAMKSNLEEINWRDVYSCFLD 87   Encephalitozoon c...
19114235  241 PLTALFGPMKASKATLKSMKEAILKkyPPGTATETDVAYLINSLVAIHDYGAWDTVLMGKAIVSSFENLNWEAMLSMFDN 320  fission yeast
10383811  264 KYFLSAPLMPTTASLSCLFAALHDG---PVIDEFFSCDWKVIFKLDLAIQLHKWSVQNGCFDL--LNAEGTRKVSETIPN 338  baker's yeast
19074937   88 VNFSIWTLESLYVIIDCWVYISGII---TVPYEIFFKRWKNERAQIYFLRLIIESDEKRTQLY--SNVFFTRIVSIEDSR 162  Encephalitozoon c...
19114235  321 PKFMIT-GTPSLVLFFTIFTNAYKLrqtNFTLDFLWVLWRNPLP-QLSIISHIILSPTSMFDIreFNVNPVVSVDSLKDY 398  fission yeast
10383811  339 TKQSLLY--LLSIASLNLELFLQRE-ELSDGPMLAYFQEcFFedFNYAPEYLILALVKEMKRFVLLIENRTVIDEILITL 415  baker's yeast
19074937  163 GHRFKNV--MGYESNFNCVELFQCIgMLGSLPLIELIAR-------KSPEWCAAGLGFVQPKFS----------RIFEEL 223  Encephalitozoon c...
19114235  399 SEELVNYakIYEKSNLNCIELVQIL-LRLLSEVVTYETS-LF--LNFLDEKVSAELLLLGTLQLPLAWNPVQESLAFQWC 474  fission yeast
10383811  416 LIQVHNKSPSSFKDVISTITDDSKIVDAAKIIINSDDAPIANFLKSLLDTGRLDTVINKL-P--FNEAFKILPCARQIG- 491  baker's yeast
19074937  224 LMGFAKGAPNSFVFHVLFRSHPEMMLQKS-LVLAKEGIPVSRLLDIFLEHKMLPLVSELLdPpeLCFDIIVLSSIRDHLn 302  Encephalitozoon c...
19114235  475 SDFFSNFKEHKFVFVRIERTNPQFLFAFLRSLWLKDSSSVNQVVEFIIENDFTSHIGNIQ-PnrFALEIAALAAARKALs 553  fission yeast
10383811  492 ---WEGFDTFLKTKVSPSNVDVVLESLEVQTKMTDTNTPFRSLKTFDLFAFHSLIEVLNKCPLDVLQ----LQRFESLEF 564  baker's yeast
19074937  303 lgiWLSNNLTTRKD-D----FVRSLVQYLDSKVSKHKEPEK------MFPLN--IEIMGTFTKAVEQy---IRILKPETV 366  Encephalitozoon c...
19114235  554 fqdWLDKKMLEFEDADGLNVFLVEVLDFLMSRAALQKNESEQKEESVVLSIDTVNVLLTTLMDNVSIseevSEHIKDVQI 633  fission yeast
10383811  565 SLLIAFPRLINFGFGHDEAILANGDIAGINNDIEKEMQNYLQKMYSGELAIKDVIELLRRLRDSDLPRDQEVFTCITHAV 644  baker's yeast
19074937  367 VVYNEFKSRIPHGLR-----AQ----RSKEIRIEEEASSFISQIINSQRGIESSINQIKEFLRG-NALSKELASRIFSAL 436  Encephalitozoon c...
19114235  634 LCLQVYPRLFSLGHDRDSIVIATNTTNSFSPDVESEVESYFQALYERRISIGKIVLTLQNFKKSENPRDLDLFACLQHSL 713  fission yeast
10383811  645 IAESTFFQDYPLDALATTSVLFGSMILFQLLRGFVLDVAFRIIMRFAKEPPESKMFKFAVQAIYAFRIRLAEYPQYCKDL 724  baker's yeast
19074937  437 LENYGSLYKLPNS--DLIALLYGGLIKERVFPKPYLRMAIEYIKGSLKHPENEREYSFGFRCLEVF---LPSYPSILSEV 511  Encephalitozoon c...
19114235  714 FDEYRFFPDYPLEALALTAVLFGSLIQFELLSFVPLGVALRYVYQALLMPTDSKMFRFGMQALVQFQEKLPKYINYCNLI 793  fission yeast
10383811  725 LRdVPALKS-QAQVYQSIVEAAT-LANAPKER---------SRPVQEMIPLKFFAVDEVS--CQINQEGAPKDVVEK-VL 790  baker's yeast
19074937  512 EE-IETVNN--ILIKKELVLMDS--------------------ETHPMLELEDIVRLIFK--CDARNESRATEVIKS--- 563  Encephalitozoon c...
19114235  794 LG-IPSLQLvRPDIYDSIREMIAsNENTEVEKdkldsfsalANPASPKAPEYTFVSIHVPplNVPNAEGEIEESVCDnIL 872  fission yeast
10383811  791 FVLNNVTLANLNNKVDELKKSLTPNYFSWFSTYLVTQRAKTEPNYHDLYSKVIVAMGSGLLHQFMVNVTLRQLFVLLSTK 870  baker's yeast
19074937  564 ------LDLRRGDDIHRLSEALEQGLVGGEEIIMHIIRSTAFEDCRRFV-EVVERLG-KDFYLRFSRKSLEFLKMLLDYR 635  Encephalitozoon c...
19114235  873 FAINNLSQLNFNEKLKDVKDNLTPAYLPWFSHYIVTQRVSREANFLSLYGKFLEELKSSDLYKIVFRDTLQAILDIMNNN 952  fission yeast
10383811  871 DE--QAIDKKHLKNLASWLGCITLALNKPIKHKNIAFREMLIEAYKENRLEIVVPFVTKILQRASESKIFKPPNPWTVGI 948  baker's yeast
19074937  636 CR--S--EVKVAKSLGLVLGRVMLAKNRIVTSEQFDFKKFVVKSVECRRILFGVSFISSFLRQGKCGIVFIPNNPWVMSI 711  Encephalitozoon c...
19114235  953 AEtlSPSEKTNLKNLGSWLGSITLLRNKPITTLQVSFKDLLLEGIDSGRIDRVLPFVCKVLEKASSSVIFKPPNPWLMGI 1032 fission yeast
10383811  949 LKLLIELNEKANWKLSLTFEVEVLLKSFNLTTKSLKPSNFINTPEVIETLsgalgsitLEQQQTEQqrqiILMQQHQQQM 1028 baker's yeast
19074937  712 LDLLSEIHSCTPRVVRD--EIQGLFRHLSVELVP-KPLKSLG----LKSR------------------------K----- 755  Encephalitozoon c...
19114235 1033 LKLLVELYQFADFRLNLKFEIELLLNNLNVKMDNIEPSEMYRNHLVQKAD--------LEKELPED----VLNAEFPDGT 1100 fission yeast
10383811 1029 LIYQQRQQQQQqrqqqqqhhiSANTIADQQAAFGGEgsishdnPFnnllgstifvthPDLKRVFQMALAKSVREILLEVV 1108 baker's yeast
19074937  756 -YLAEYIIEDS----------------DLVVRHVIS--------------------------L---ALDLSVREICGAIV 789  Encephalitozoon c...
19114235 1101 DVITQYIVAAS----------SQITVTDAVAQVFGK-------PK------------PAIKNITQLIIQQSVLEIISAVV 1151 fission yeast
10383811 1109 EKSSGIAVVTTTKIILKDFATEVDESKLKTAAIIMVRHLAQSLARATSIEPLKEGIRSTMQSLAPNLMS-LSSSPAEELD 1187 baker's yeast
19074937  790 EKACSVAIQTGMALFK---TMSVEKGMEYVLFRNMVVNLTKFLCLVSAQEPIKACISGNV-SYFMKLCS--LDFSTEKVF 863  Encephalitozoon c...
19114235 1152 RRSVGIAAITTKSLLQKDFAAESNPSRLLLAARQMAKTLAGNLAMVTCREPLQMLMINNFRTIALQDVEnVHAAVAQAID 1231 fission yeast
10383811 1188 TAINENIGIALVLIEKASMDKSTQDLADQLMQAIAIRRYHKERRADQPFITQN-TNPYSLSLPEPLGLKNTGVTPQQFRV 1266 baker's yeast
19074937  864 KIAMENQDVCCRLIQRAGVSKVSESIS-------------------------------SC--YSSLEYSIGKASHARLSL 910  Encephalitozoon c...
19114235 1232 ELVSQNLFVASSVIESVASETAIAEIDAEIEHMIVERVRHRKTTPNLPFVDPAgAANLHLNLPSVLKLS-SELTPQQFQL 1310 fission yeast
10383811 1267 YEEFgknipnlDVIPFAGLPAHAPPMTQNVGLTQPQQQQAQMPTQILTSEQIRAQQQQQQLQKSRLNQPSQSAQppgVNV 1346 baker's yeast
19074937  911 LEDP----------------GHIEKIAIKAIDS----------N---------------EYQE----IKAHLVQ---LSK 942  Encephalitozoon c...
19114235 1311 YENF-------DRLSLSTIMSNNSFTSLNGLRTDSADSTDALNSNLNNTVENEANQTALNYARNLLIIIGQLFQ---LAA 1380 fission yeast
10383811 1347 PNPQGGIAAVQSDLEQNqrvlvhlmdilvsQIKENAtkNnlaelgdqnQIKTIIFQILTFIAKSaqkDQLALKVSQAVVN 1426 baker's yeast
19074937  943 KIPYS-KKNVIADEWHG-------------LLKEGK--------------EEVFRRILESVESS---EDKDEECIRLCRY 991  Encephalitozoon c...
19114235 1381 QMPYTSMQEVPADHE----------------LHELV--N---------QFLTGVASINHPIA-----DHVFLLCAQECCR 1428 fission yeast
10383811 1427 SLFATSESPLCREVLSLLLEKLCSLSLVARKDVVWWLVYALDSRKFNVPVIRSLLEVNLIDATELDNVLVTAMKNKMEN- 1505 baker's yeast
19074937  992 ITGHLIKSGSKEDFLFRCMEKIFKISFKTQKEVLGWLIYSNDPRKFSISLVGKFIEHNLINVVEYDQALS-KIPLADGN- 1069 Encephalitozoon c...
19114235 1429 ILLTDSKSPFILEVFSAILEYICQASTKTAINVSLYWNFSNDLEKLNLPIILSLIRFGILTSGEVDYHVARGVRSEQGSg 1508 fission yeast
10383811 1506 -STEFAMKLIQNTVLSDDPILMRMDFIK---TLEHLASSED-ENVKKFIKEFEDTKIMPVRKG--------TKTTRTEKL 1572 baker's yeast
19074937 1070 --LDFVIALLASLITAEVQICTVYDFIC---TLEMLAGHSDnPKVFDFFQKISNLMMHIEAKG----------------- 1127 Encephalitozoon c...
19114235 1509 pVTDFAIELLRTAVGGENPMALPGNFVNsitSLYEISESFS-GETKQAYEQLVETMNKSVSPAseilsdldNKQQLNDQI 1587 fission yeast
10383811 1573 YLVFTEWVKLLQRVENNDVITTVFIKQLVEKGVISDTDNLLTFVKSSLELSVSSFKESDPT-DEVFIAIDALGSLIIKLL 1651 baker's yeast
19074937 1128 ---VSEYDEYVRNCRFT-TVPEMFLPEFMERTDYPASLDIRSAFKVSWDHFIR--HHRIPT-AYCYLKIDPLPGLIKNRL 1200 Encephalitozoon c...
19114235 1588 IIVFVSWVHLLRNSATNDETKAAFVYQLHKQGILSEPELCIQFFRCNLEAVLVAFLEAASVnAPDYFNVDAYASLLVNVV 1667 fission yeast
10383811 1652 IL-QGFKDDTRR---DYINAIFSVIVLVFAKDHSQEGTTFNERPYFRLFSNILYEWATIRthnfvrISDSStrqELIEFD 1727 baker's yeast
19074937 1201 YE------------------SIKDSLFVFLEAYRKR-----NYLFFKLYTRFIIKTLDVI-------EDTP------NNR 1244 Encephalitozoon c...
19114235 1668 KYtEGSTEGTVSsksVLFRKIIALIIGVFAELHNSMAEFVHQKTFFRLFSSILSELDDAK------DVLES---CFVDIY 1738 fission yeast
10383811 1728 SVFYNTFSgylhALQPFAFPGFSFAWVTLLSHRMLLPIMLRLPNKIGWEKLMLLIIDLFKFLDqyTSKHAVSDAVSVVYK 1807 baker's yeast
19074937 1245 SLVYSILE----VLSPSRVPGFTSCFLEILTHKFVS-----------------G------FFD---SEEGVVLVMEALRC 1294 Encephalitozoon c...
19114235 1739 SVILECFL----AIQPRSFPAFTFAWLSLISHSYLLPKVLLVNNDKINDLFSEILMSFLKFLD--LKDDIDKAQFKLLYN 1812 fission yeast
10383811 1808 GTLRVILGISNDMPSFLIENHYELMNNLPPTYFQLKNVILSAIPKNMTVPNPYDVDLNMEDIPACKELPEVFFDPVIDLH 1887 baker's yeast
19074937 1295 GFYSTRLVY----P---ITQIMQSFRRNP---VHAR--MYSSY---LTYCCP-------QEYPHIKNFINQFRDRIVPVE 1352 Encephalitozoon c...
19114235 1813 GFLRIILVLLHDFPGFLATHCYQLIPYIPLECVQLRNMVLSAFPSDLHLPDPFAQGLKVGRLPEVTRAPLISNSVSASLE 1892 fission yeast
10383811 1888 SLKKPVDnyLRIPSNSLLRTILSAIYKDTYDIKKgVGYDFLSVDSKLIRAIVLHVGIEAgieykRTSSNAVFNTKSSYYT 1967 baker's yeast
19074937 1353 GQNSFFR------LRTALQNRTSVKVTDLGIGKN---LWVYLIDNLNEMDAVSSTVVES-----IKFMIERKMHLEEILT 1418 Encephalitozoon c...
19114235 1893 KFASALD--LEACFSSSKPAEVAKLLLEVYSSQD-TPTKLNEWANYFMLCLIRHATRDS-----PAKQAPQFQSKSPECV 1964 fission yeast
10383811 1968 LLFNLIQNGSIEMKYQIILSIVEQLRYPNIHTYWFSFVLMNMFKSDEWNDQKLEVQEIILRNFLKRIIVNKPHTWGVSVF 2047 baker's yeast
19074937 1419 MLWIRMRAGGPPK-------ALAAC-YDEISSFDFCRVFLKSLESHGYN--KL--------------------------- 1461 Encephalitozoon c...
19114235 1965 IISTMNRSCDSKCRYFLLTAIANQLRYPSSHTYYASCCFLYLFKSSSNNPQELLIKEQMTTVLLERIICNRPHPWGLLIT 2044 fission yeast
10383811 2048 FTQLINNNDINLLDLPFVQSVPEIKLILQQLVKYSKKYTTSEqddqsATINRRQTPLQSNA 2108 baker's yeast
19074937      -------------------------------------------------------------      Encephalitozoon cuniculi
19114235 2045 FTELLKNEDYNFWKHPYIKRNDEICRLFDSLHEHVMAPSSAN-----NVSTEEATELMGQV 2100 fission yeast
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