Conserved Protein Domain Family
DUF726

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pfam05277: DUF726 
Protein of unknown function (DUF726)
This family consists of several uncharacterized eukaryotic proteins.
Statistics
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PSSM-Id: 368366
Aligned: 7 rows
Threshold Bit Score: 454.925
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
O14244     351 SRRKKYILMGLAGIGGGLVIGLSSGLLAPIISAGIGAAFTTV--GLSGVATs-gFLAg--GGSAaLITAGGAISGAHIGT 425  Schizosaccharomy...
P43564     536 KRRKKMAYVALAMVGGSLVLGLSGGLLAPVIGGGIAAGLSTI--GITGATS---FLTg-vGGTT-VVAVSSTAIGANIGA 608  Saccharomyces ce...
Q9US10     167 RKMRRRIAMGLAGLAGGALIGLTGGLAAPFVAAGLGTLFAGL--GL-GTMIgatYLGtliT-SApMITALFGGFGAKMSM 242  Schizosaccharomy...
XP_956878  366 RRWRH----GLASMAGISSFGIPGHLAPPLVAAGIGSVNGGFglGPTASAG---ILGs-tGESAfVVGALLGIYNARTSV 437 
Q8I5Y6     743 RNIRR-MKIAAAALGGGALIAFTAGLAAPGIIAGLTAL------GAGGSSLt-aFLAs-aSGLA-FIVSLFGAGGAGLTG 812  Plasmodium falci...
Q91WU4     182 RKWKRYLLIGLATVGGGTVIGVTGGLAAPLVAAGAATII-----GSAGAAA----LGs-vAGIA-VMTSLFGAAGAGLTG 250  house mouse
Q20035     213 KKIKRYLMIGAAGGVGGVLIGLTGGLAAPLVAASAGMLI-----GGGAVAG----LAt-tAGAA-VLGTTMGVAGAGFTG 281  Caenorhabditis e...
O14244     426 TGMAHRKADVKTFEFRPLHAQRRa------------NVIVTVSGWM-LSKEDDVRLSFATLDPIV-----GDIYSVFWEP 487  Schizosaccharomy...
P43564     609 RGMSKRMGSVRTFEFRPLHNNRRv------------NLILTVSGWM-VGNEDDVRLPFSTVDPVE-----GDLYSLYWEP 670  Saccharomyces ce...
Q9US10     243 QQMGDVSKGLTDFEFIPLSVQSHl------------PVTIGISGWL--GDYNEVDAAWKSLTVGDksyywGDIYALKFEV 308  Schizosaccharomy...
XP_956878  438 KLMEQCTKEIQDFAFIPMRGSIGqdgeigkiqpdarRLRVVLAISGwLTDESDVTNPWRALGQA------NEVYAVRWEV 511 
Q8I5Y6     813 YKYSRRIANIKTFEFIMLNGNIs------------kSLSVCVCVSGeIKSDDDITNPWLEVFPNCy----CDLYCLKWEN 876  Plasmodium falci...
Q91WU4     251 YKMKKRVGAIEEFMFLPLTEGRQl------------HITIAITGWLgSGRYRTFNAPWMALARS------QEQYCLAWEA 312  house mouse
Q20035     282 YKMKKRVGAIEEFSVETLSEGVSls----------cSLVVSGWIESdTSPDQAFVHQWRHLRHT------KEQYTLRYES 345  Caenorhabditis e...
O14244     488 EMLASAGQTM-NILATEVVTQSLQQV-LGSTV---------------------LVSLMGALQWPLILTKLGYLIDNPWNN 544  Schizosaccharomy...
P43564     671 EMLKSIGQTV-SIVATEIFTTSLQQI-LGATV---------------------LTALISSIQWPMALSKLGYILDNPWNV 727  Saccharomyces ce...
Q9US10     309 EALVDLGKSLsRILFSAGLGWVKGEV-ISRTI---------------------LAPLAAAL-WPLSLLKVGNILGNSWRI 365  Schizosaccharomy...
XP_956878  512 DSLSKMGTALeTVVRSSAWSMAKKEI-IARTSeppfnipkcnlsrrankhgpvFTSMTESL-WPLGLLKINKIIDNPWSV 589 
Q8I5Y6     877 HLLKTLGSLIeTML-SQEFAITASRIwLQYTI---------------------ASTLSAALTWPLALIKYASNLDNVYLL 934  Plasmodium falci...
Q91WU4     313 KYLMELGNALeTIL-SGLANMVAQEA-LKYTV---------------------LSGIVAALTWPASLLSVANVIDNPWGV 369  house mouse
Q20035     346 NYLMELGNAI-EYLMSFAVSVAIQQT-LLETA---------------------LAGLVSAVAWPVALMSVSSVLDNPWNV 402  Caenorhabditis e...
O14244     545 SLDRAKATGQLLADMLCYRSL-GVRPVTLVGYSLGARVIYYCLRELEKK-KEFSIIENVYLFGTPVIFKRTSWLKAASVV 622  Schizosaccharomy...
P43564     728 SLDRAWSAGKILADTLIARNL-GARPITLVGFSIGARVIFSCLIELCKK-KALGLIENVYLFGTPAVMKKEQLVMARSVV 805  Saccharomyces ce...
Q9US10     366 AFNLSIKAGEALANALCVRAQ-GMRPVTLIGFSLGARTILECLLHLADR-GETNLVENVIVMGAPMPTDAKLWLKMRCVV 443  Schizosaccharomy...
XP_956878  590 GMVRADKAGTLLADAIMNKAH-GERGVTLIGYSLGARAIYVCLMVLAER-RAFGLVENAVMMGTPAPSEARVWCTMRSVV 667 
Q8I5Y6     935 IRERAQQAGRILADALSDRNTvGQRPVILIGYSVGARVIFYCLKYLYSK-KLYNIVSNAIFIGLPATTSTKVWEKIRMVV 1013 Plasmodium falci...
Q91WU4     370 CLHRSAEVGKHLAHILLSRQQ-GRRPVTLIGFSLGARVIYFCLQEMAQEqDCQGIIEDVVLLGAPVEGDPKHWEPFRNVV 448  house mouse
Q20035     403 CVSRAAEVGEQLAEVLLSRSH-GKRPITLIGFSLGARVIFHCLLTMSKRsESVGIIEDVILLGAPVTASPKEWSKVCTVV 481  Caenorhabditis e...
O14244     623 SGRFVNGYKKNDWILGYLFRATSGGIgRVAGLRQIDC--IPGIENIDVTNLVSGHLAYRESMPILLAAVGFE 692  Schizosaccharomyces pomb...
P43564     806 SGRFVNGYSDKDWFLAYLFRAAAGGFsAVMGISTIEN--VEGIENINCTEFVDGHLNYRKSMPKLLKRIGIA 875  Saccharomyces cerevisiae...
Q9US10     444 AGRFVNVYSASDYVLQLVYRVNSAQS-TAAGLGPVSLd-SNTLENVDVGDLVEGHLQYRWLVAKILKE-RLG 512  Schizosaccharomyces pomb...
XP_956878  668 SGRLVNVFSENDYLLGFLYRTSSIQF-GVAGLQRIEg--IDGVENVDVSAKVSGHLRYQYLAGSILKHINWE 736 
Q8I5Y6    1014 TNRVINVYSKNDWLLGFLYRYMEW---KINVAGLIAVk-VPNVENYDASGIIHSHLDYKRKLKDIFHLINFD 1081 Plasmodium falciparum 3D7
Q91WU4     449 SGRIINGYCRGDWLLSFVYRTSSVQL-RVAGLQPVLLq-dRRMENVDLTSVVNGHLDYAKQMDAILKVVGIR 518  house mouse
Q20035     482 SGRVINGYCETDWLLRFLYRTMSAQF-RIAGTGPIDNrnSKKIYNYNLSHIVKGHMDYSKRLTEVLNAVGVK 552  Caenorhabditis elegans
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