Conserved Protein Domain Family
FlaA1

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COG1086: FlaA1 (this model, PSSM-Id:224011 is obsolete and has been replaced by 440703)
NDP-sugar epimerase, includes UDP-GlcNAc-inverting 4,6-dehydratase FlaA1 and capsular polysaccharide biosynthesis protein EpsC [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones]
Statistics
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PSSM-Id: 224011
Aligned: 34 rows
Threshold Bit Score: 458.659
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
16264484 312 DREAIGRLVRGRRVLITGAGGSIGSELTAQVAAC----EPAEIVLIDNTEYNLYAIDMTLTESFP---ELPRWSYLCSVR 384 Sinorhizobium meliloti
19705010   1 -------MLNNSTILITGGTGSFGNRFIERILSEy---NPKKIIIYSRDEFKQDLMKKNFVMKYGvekTKKLRFFIGDVR 70  Fusobacterium nucle...
15645459   1 -MPNHQNMLDNQTILITGGTGSFGKCFVRKVLDTt---NAKKIIVYSRDELKQSEMAMEFND-------PRMRFFIGDVR 69  Helicobacter pylori...
15669250   1 MFQDISNFYKDKTILVTGGTGSIGKEIVKTLLKF----NPKTIRVLDINETALFELEHELNS-------EKIRCFIGDVR 69  Methanocaldococcus ...
15602872   1 -------MFKNKTLLITGGTGSFGNAVLKRFLET----DIREIRVFSRDEKKQDDMRKKYND-------AKLKFYIGDVR 62  Pasteurella multocida
15892380   1 -------MFVDKTLMITGGTGSFGNAVLSRFLKSgiinDIKEIRIFSRDEKKQEDMRIALNN-------PKLKFYIGDVR 66  Rickettsia conorii
15604201   1 -------MFVDKTLMITGGTGSFGNAVLSRFLKSniinDIKEIRIFSRDEKKQEDMRIALNN-------SKLKFYIGDVR 66  Rickettsia prowazekii
15925857   1 -------MFDDKILLITGGTGSFGNAVMKRFLDS----NIKEIRIFSRDEKKQDDIRKKYNN-------SKLKFYIGDVR 62  Staphylococcus aure...
15900287   1 -----MSQFTGKTLLITGGTGSFGNAVLKRFLET----DVSEIRIFSRDEKKQDDMRHEFQVKVPe-vAGKIRFYLGDVR 70  Streptococcus pneum...
15611845   1 -MPNHQNMLDNQTILITGGTGSFGKRFVRKVLDTt---NAKKIIVYSRDELKQSEMAMEFND-------PRMRFFIGDVR 69  Helicobacter pylori...
16264484 385 RSQRVEEIFERhrPELVFHAAALKHVPMVQMNPCEGVLTNVVGTMNVANAAKKYGTLAMVQVSTDKVVNSTSVMGATKRL 464 Sinorhizobium meliloti
19705010  71 DKERLYRAFDG--VDYVIHAAAMKQVPACEYNPFEAIKTNIHGAENVIEAAIDRGVKKVVALSTDKAVNPINLYGGTKLV 148 Fusobacterium nucle...
15645459  70 DLERLNYALEG--VDICIHAAALKHVPIAEYNPLECIKTNIMGASNVINACLKNAISQVIALSTDKAANPINLYGATKLC 147 Helicobacter pylori...
15669250  70 DKDRLKRAIEE--VDVVFHAAALKHVPLCEYNPFEAVKTNVIGTQNLIEVAMDEEVEKFITISTDKAVNPVNVMGATKLL 147 Methanocaldococcus ...
15602872  63 DYDSILNASRG--VDYIYHAAALKQVPSCEFYPLEAVKTNILGTANVLEAAIQNQIKRVVCLSTDKAVYPINAMGISKAM 140 Pasteurella multocida
15892380  67 NYKSIDEAMHG--VDYVFHAAALKQVPTCEFYPMEAINTNVLGAENVLSAAINNKVTKVIVLSTDKAVYPINAMGLSKAL 144 Rickettsia conorii
15604201  67 NYQSIDDAMHG--VDYVFHAAALKQVPTCEFYPMEAINTNVLGAENVLSAAINNKVTKVIVLSTDKAVYPINAMGLSKAL 144 Rickettsia prowazekii
15925857  63 DSQSVETAMRD--VDYVFHAAALKQVPSCEFFPVEAVKTNIIGTENVLQSAIHQNVKKVICLSTDKAAYPINAMGISKAM 140 Staphylococcus aure...
15900287  71 DLASVKNAMHG--VDYVFHAAALKQVPSCEFFPVEAVKTNILGTENVLTAAIEAGVKQVICLSTDKAAYPVNAMGTSKAM 148 Streptococcus pneum...
15611845  70 DLERLNYALEG--VDICIHAAALKHVPIAEYNPLECIKTNIMGASNVINACLKNEISQVIALSTDKAANPINLYGATKLC 147 Helicobacter pylori...
16264484 465 AELYCQALDLNGLETglGPRFMTVRFGNVLGSSGSLIPLFKRQLARG-GPLTVTDANMTRFFMTIREAVELTLQASAYgf 543 Sinorhizobium meliloti
19705010 149 SDKLFISANA-YSGEk-GTIFSVVRYGNVAGSRGSVIPFFKQLLSQGkTELPITDIHMTRFWMVLDDAVNLVLKALKE-- 224 Fusobacterium nucle...
15645459 148 SDKLFVSANN-FKGSs-QTQFSVVRYGNVVGSRGSVVPFFKKLVQNKaSEIPITDIRMTRFWITLDEGVSFVLKSLKR-- 223 Helicobacter pylori...
15669250 148 AERLTISANL-YKGKr-KTAFSVVRFGNVLNSRGSILPLLKEQIKKG-GPVTLTHPDMTRFIMSINEAVKLVLKACYL-- 222 Methanocaldococcus ...
15602872 141 MEKVIIAKSRNLEGT--PTTICCTRYGNVMASRGSVIPLFVDQIRQG-KPFTITDPEMTRFMMTLEDAVDLVLYAFKN-- 215 Pasteurella multocida
15892380 145 MEKLAIAKAR-MRSPg-ETVLCVTRYGNVMASRGSVIPLFINQIKQG-KVLTITEPSMTRFLMSLVDSVDLVLYAFEH-- 219 Rickettsia conorii
15604201 145 MEKLAIAKAR-MRSPg-ETILCVTRYGNVMASRGSVIPLFIHQIKQG-KELTITEPSMTRFLMSLVDSVDLVLYAFEH-- 219 Rickettsia prowazekii
15925857 141 MEKVFVAKSRNIRSE--QTLICGTRYGNVMASRGSVIPLFIDKIKAG-EPLTITDPDMTRFLMSLEDAVELVVHAFKH-- 215 Staphylococcus aure...
15900287 149 MEKIAVAKSRTVNPE--HTKICVTRYGNVLCSRGSVVPLWIEQIKQG-NALTITEPSMTRFVMTLEEAVDLVLFAFEE-- 223 Streptococcus pneum...
15611845 148 SDKLFVSANN-FKGPs-QTQFGVVRYGNVVGSRGSVVPFFKKLVQNKaSEIPITDIRMTRFWITLDEGVSFVLKSLKR-- 223 Helicobacter pylori...
16264484 544 ekqLGQGEIFVLDMgEPIKIIDIARRMIRLAG---FTPDQEIEIKIIGCRPGEKLFEELFDETDKRTSSPVPGVLGAVPE 620 Sinorhizobium meliloti
19705010 225 ---SKGGETFVFKN-PSFLITELAKAL----------NPNG-IIKEVGIREGEKIHEVMITRDDAKYTYDYEDYYVIYPN 289 Fusobacterium nucle...
15645459 224 ---MHGGEIFVPKI-PSMKMTDLAKAL----------APNT-PTKIIGIRPGEKLHEVMIPKDESHLALEFEDFFIIQPT 288 Helicobacter pylori...
15669250 223 ---AKGGEIFILKM-PSVRIKDLIEVVIEELApkyGYKPEDIEIKIIGKRPGEKLYEELIIEEEIYNLEELEDMFVVYPY 298 Methanocaldococcus ...
15602872 216 ---GQNGDVFVQKA-PAATIGTLAKAITELL------SVPNHPISIIGTRHGEKAFEALLSREEMVHAINEGNYYRIPAD 285 Pasteurella multocida
15892380 220 ---GHQGDIFVQKS-PASTIEVLAKALQDIF------DSKN-EIRFIGTRHGEKHYESLVSSEEMAKADDLRDYYRIPMD 288 Rickettsia conorii
15604201 220 ---GRQGDIFVQKS-PASTIEVLAKALQEIF------GSKN-AIRFIGTRHGEKHYESLVSSEDMAKADDLGGYYRIPMD 288 Rickettsia prowazekii
15925857 216 ---AETGDIMVQKA-PSSTVGDLATALLELF------EADN-AIEIIGTRHGEKKAETLLTREEYAQCEDMGDYFRVPAD 284 Staphylococcus aure...
15900287 224 ---GKSGDILVQKA-PACTIEVLAKAVSEIF------ASEQ-DIKIIGIRHGEKRYETLLTNEECANAIDLGDFYRVPSD 292 Streptococcus pneum...
15611845 224 ---MHGGEIFVPKI-PSMKMIDLAKAL----------APNI-PTKIIGIRPGEKLHEVMIPKDESHLALEFEDFFIIQPT 288 Helicobacter pylori...
16264484 621 PIPLPT----LRDAFARLQRHSERGNEAGVVAVMRELLPRYEHEADRKMAA 667 Sinorhizobium meliloti
19705010 290 FEWWNK-----EKIKSGGKLIPENWDYNSGTNDWWLDAKELEKRIAKLDIK 335 Fusobacterium nucleatum subsp. nucleatum ATCC 25586
15645459 289 ISFQTPkdytLTKLHEKGQKVAPDFEYSSHNNNQWLEPDDLLKLL------ 333 Helicobacter pylori 26695
15669250 299 GVDGNK----------NNK-----IIYNSK-DAKFLNKEKIKKILKEISYL 333 Methanocaldococcus jannaschii
15602872 286 QRSLNY----SKYVEKGEPKITEVTDYNSH-NTERLTVKEMKQLLLKLEFI 331 Pasteurella multocida
15892380 289 GRDLNY----AKYFVEGEKKVALLEDYTSH-NTKRLNLEEVKELLLTLDYV 334 Rickettsia conorii
15604201 289 GRDLNY----AKYFVTGEKKVALLDDYTSH-NTKRLNLKEVKELLLTLDYV 334 Rickettsia prowazekii
15925857 285 SRDLNY----SNYVETGNEKITQSYEYNSD-NTHILTVEEIKEKLLTLEYV 330 Staphylococcus aureus subsp. aureus N315
15900287 293 NRNLNY----DKYFKDGSTNRNLLTEFNSN-NTDLMDVEQVKRKLLELDEI 338 Streptococcus pneumoniae TIGR4
15611845 289 ISFQTPkdytLTKLHEKGQKVAPDFEYSSHTNNQWLEPDDLLKLL------ 333 Helicobacter pylori J99
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