16081411 327 YNMIFSVSGNDVfgiypeNGSYGTIYTGKdsvlaiastqgesgfpsafIVLTKGLFTVLSAPDKISEsVSIPAsLnriSS 406 Thermoplasma acidop... 1352644 28 GKPTTNSIEIIKrlfqnkWAILFFLLIVVivllaii------vpltspFSAVTPVSTNALAQNLPPRyLWHKP-GdilVH 100 Mycoplasma genitalium 2501378 28 GKPTTNFVEIMKrlfqnkWAILFFLLIVLiillaii------vplaspYSAVTPVSNNALAQNLPPRyLWNGA-GdiqVE 100 Mycoplasma pneumoniae 15828755 4 NKNTQHKLSEADlallnfASQNNLNAALVgkpktfwkdivlrffqnkfAVFALIVFLVVFLMSIFVP-IFSPYsStkpIS 82 Mycoplasma pulmonis 15828882 1 ----------------mqqkkLDDYFSEVarpnkf--------vqpfqYQGWKLMKNQANLADDLQFkSNISI-YkefIN 55 Mycoplasma pulmonis 14591569 14 FLIAFITIANISiksediKNWNNANYWSEnpksaypiwfcyitdktrtTELIGEGNIIYVHKFEDRPnDVIFYnAsgaVV 93 Pyrococcus horikoshii 113713 1 ----------------------------------------mstidkekFQFVKRDDFASETIDAPAYsYWKSV-FkqfMK 39 Streptococcus pneum... 15674467 1 ----------------------------------------mesidkskFRFVERDSEASEVIDTPAYsYWKSV-FrqfFS 39 Streptococcus pyoge... 15898117 81 LSPINMSLYSPAknifvaIITYQFNWSKVlpaynvyfitssnvtpieeVIYWSKPDGYTLQVNVPAGvFNVPFdLtsiRG 160 Sulfolobus solfatar... 13358125 1 ------MAKFGEylkqksKSITSSFIDELtsdapnk------flqpfqHQQWKIIGHLIEFRDNAYMgGRPRP-FrefAN 67 Ureaplasma urealyticum
16081411 407 DQLDFlvyddsgymimaeyLTSSEPfawftnlnthiskpqffvnpesaresiamlvgnklniysvngkdlnplpptlnvp 486 Thermoplasma acidop... 1352644 101 KITARsiaeis--qasgvlVGTLPSansnplatnvq---------------------------------ydiapfqlqel 145 Mycoplasma genitalium 2501378 101 KITARsiaeva--qssgvlVGKLPEassnplatnvk---------------------------------yniapyqlael 145 Mycoplasma pneumoniae 15828755 83 TADVSlvqklpssignkphRVLISSdfldilknleannpgtkiilesq---------rlgnqvrisyypylalsllsptk 153 Mycoplasma pulmonis 15828882 56 RFSRSfagvfg--vviilfFIISAFiipfttgspie---------------------------------lrpsqknydff 100 Mycoplasma pulmonis 14591569 94 TIVRPdgriiklrlpkkeeISLNIYgkysivsqlnippqkaalktatfllfssykdlevlkgkyifkingtnktirivik 173 Pyrococcus horikoshii 113713 40 KKSTVvmlgil--vaiiliSFIYPMfskfdfndvsk---------------------------------vndfsvryikp 84 Streptococcus pneum... 15674467 40 KKSTVfmlvil--vtvlmmSFIYPMfanydfndvsn---------------------------------indfskryiwp 84 Streptococcus pyoge... 15898117 161 DILSYissitgktpnivnsTVLSSAlfnspksnftvieqgkyvvk----------------ieivsslpmnitksrlill 224 Sulfolobus solfatar... 13358125 68 RYGRSfsglig--laiiiiLFILAIiipfttgspte---------------------------------lrpnkryldyf 112 Ureaplasma urealyticum
16081411 487 AGGPLLLGTTDHGKDVWSLFIGSFPTDLYIGVVVGIGILLISMVIGMLIGYFTG--IVSSLVETfSLAVYLIPGLPLLIV 564 Thermoplasma acidop... 1352644 146 RNYFPLLGTNGLGIDIWTLLWASVAKSLWIAVVVAIIAMVFGTIYGAVAGSFVGhmADNIMSRI-IEIIDIVPSILWIIV 224 Mycoplasma genitalium 2501378 146 KNYYPLLGTNGLGVDIWTLLWASMAKSLWIAIVVALVSMVFGTIYGAIAGSFVGraADNIMSRI-IEIIDLVPSILWIIV 224 Mycoplasma pneumoniae 15828755 154 QQFSSIIGTDSFGRDLWLTSWEGTRNALLLGFIVGTIQTFIGIIVGTYMGFHIGkkVDNILMRV-IEIINSIPWFLIFII 232 Mycoplasma pulmonis 15828882 101 QEGF-ILGTDNQGRDLWAYLWHGLRFSLALACIVALIDITVATLIGILMG--YFdkFDKVMTFI-IKVISNVPTILVMIL 176 Mycoplasma pulmonis 14591569 174 GNCYGIFGTDKYGRDMWVGFIAGTNNTILLTLLIGGSMLIFGIIIGIASAYNKL--IDFILEVIaSTPMLPFFMILVWLV 251 Pyrococcus horikoshii 113713 85 NAEH-WFGTDSNGKSLFDGVWFGARNSILISVIATVINLVIGVFVGGIWG--ISksVDRVMMEV-YNVISNIPPLLIVIV 160 Streptococcus pneum... 15674467 85 NAEY-WFGTDKNGQSLFDGVWYGARNSILISVIATLINITIGVVLGAIWG--VSkaFDKVMIEI-YNIISNIPSMLIIIV 160 Streptococcus pyoge... 15898117 225 GNSYGLMGTDYFGRPLDLGILLGLPNALEIGVLTSLVAVLVGVFVGGISGYLGGn-KDSIIQWV-TLVFLALPALPFLVA 302 Sulfolobus solfatar... 13358125 113 TDGF-IFGTDNNGRDLWAMLWWGLRYSLGIAIIVTAIELVVGVTLGILMG--YFemFDKIMTFI-IKILTNVPTIIILMI 188 Ureaplasma urealyticum
16081411 565 VASIVG--P----SLIg--LIAVLTFLSWPFPTFTLIGIIRSLKSRAFVEAAKISGASTMYILRKHMLPNITPILVYLTA 636 Thermoplasma acidop... 1352644 225 LGATFRfggvkqfDDSv--VIFTLIFVFWTWPATTTRIYILKNKDTEYIQAAKTLGAHQIRIIFVHMLPVVFGRLAVVFV 302 Mycoplasma genitalium 2501378 225 LGATFRfggvkqfDDSv--VIFTLIFVFWTWPAATTRIYILKNKDTEYIQAARTLGAKQIRIIFVHMLPVVTGRLAVVFV 302 Mycoplasma pneumoniae 15828755 233 LVQILG--T----DYLs--IGIILIVLGWTNPTYVARSYTSIIKDEEFLYASKVVGASKLRIIYLEALPQIIGKLTNVYL 304 Mycoplasma pulmonis 15828882 177 MTIVLRp------sFGv--LIFSMTVTGWTGLANQVRAQIKRARNFVWVSASRLLCTPGWKIILN-FVPIIIPLIITNLV 247 Mycoplasma pulmonis 14591569 252 STQGIGynV----NIStidFVLILTILSVGRFAKSIKSITLKERAMEYTKASISLGADENWIIRRHILKPVLEFSLRHVT 327 Pyrococcus horikoshii 113713 161 LTYSIGa------gFWn--LIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKNIMPQLVSVIVTTMT 232 Streptococcus pneum... 15674467 161 LTYSLGa------gFWn--LILAFCITGWIGVAYSIRVQILRYRDLEYNLASQTLGTPMYKIAVKNLLPQLVSVIMTMLS 232 Streptococcus pyoge... 15898117 303 VSFVAE--P----NIVi--EALLIAFLSWPFYAIIARSMALSIKSNSYVEADKLLGIPSYRVFFTHFMPRLIPITVAYMV 374 Sulfolobus solfatar... 13358125 189 LTIILKp------sFGv--MIFAISFSGWIAMANQMRSQVKRARSFLWVAASKTLGTKAWKIILN-FLPILIPMMITQLV 259 Ureaplasma urealyticum
16081411 637 INIGGAVAAVSTLQILGVA---PLNVPTWGGMLSGFYSdYfDLIIAPWWFIPPIVALTLFIFAFIFVSRGLD-EVVNPRL 712 Thermoplasma acidop... 1352644 303 SLIPAVIGYEASLVFLGLKp--AT-DIGLGALLNQVTS-----SDNVALILSSIVSFAVLTVAARTFANALN-DAIDPRV 373 Mycoplasma genitalium 2501378 303 SLIPAVIGYEASLVFLGLKp--AT-EVGLGALLNQVTS-----SGNIALITSSIVSFAILTVSTRVFANALN-DAIDPRV 373 Mycoplasma pneumoniae 15828755 305 NRIIGGIFALSSLAFLQLIfdnPSLTPNLGLILNNSTR---LIDENIWAIILPSSILAIIVITLKITFTGLH-DALDPKT 380 Mycoplasma pulmonis 15828882 248 FTIPGAVLAETGLAFIGLSl--PN-VATLGNMINEGVPiI---TLYPRYVLIPATILILITSSVQLIGASTQ-DSLRRQR 320 Mycoplasma pulmonis 14591569 328 FIIAKTISLVSILGFFGLS-----PGVNWGSYMIELMRegvLYGNYWWIVLTLVLMMGVLSLSLALISERLP-ESYG--- 398 Pyrococcus horikoshii 113713 233 QMLPSFISYEAFLSFFGLGl--PITVPSLGRLISDYSQnV---TTNAYLFWIPLTTLVLVSLSLFVVGQNLA-DASDPRT 306 Streptococcus pneum... 15674467 233 QMLPVYVSSEAFLSFFGIGl--PTTTPSLGRFIANYSSnL---TTNAYLFWIPLVTLILVSLPLYIVGQNLA-DASDPRS 306 Streptococcus pyoge... 15898117 375 LGVPAGILLAQTLAFLGIA---PANIVTWGGILDAAETyQaQVNGWWWWVVFPGAMVVIVAIPFVLIGFAIErVTLGER- 450 Sulfolobus solfatar... 13358125 260 FSIPGAILAESSLAFIGLSl--PN-TPTLGNLIADGSSiI---TLYPRFTLIPSFLLVCLVASIQLVGGATQ-DALRRQR 332 Ureaplasma urealyticum
16081411 713 SQR 715 Thermoplasma acidophilum 1352644 374 VKR 376 Mycoplasma genitalium 2501378 374 IRR 376 Mycoplasma pneumoniae 15828755 381 KKV 383 Mycoplasma pulmonis 15828882 --- Mycoplasma pulmonis 14591569 --- Pyrococcus horikoshii 113713 307 HR- 308 Streptococcus pneumoniae 15674467 307 HR- 308 Streptococcus pyogenes M1 GAS 15898117 --- Sulfolobus solfataricus 13358125 --- Ureaplasma urealyticum
Jiyao W et al.(2023). "The conserved domain database in 2023.",