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Putative manganese efflux pump MntP is a family of bacterial proteins with a signal peptide and four transmembrane domains. It is a putative manganese efflux pump, since deletion of the gene leads to profound manganese sensitivity and elevated intracellular manganese levels in bacteria. Manganese is a highly important trace nutrient for organizms from bacteria to humans, and acts as an important element in the defence against oxidative stress and as an enzyme cofactor. |
Jiyao W et al.(2023). "The conserved domain database in 2023.",