Conserved Protein Domain Family
carB
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PRK05294: carB 
carbamoyl-phosphate synthase large subunit
Links
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Statistics
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PSSM-Id: 235393
Aligned: 705 rows
Threshold Bit Score: 1397.91
Created: 9-Dec-2010
Updated: 25-Oct-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
13472276     1 MPRRTDIKSILIIGAGPIVIGQACEFDYSGTQACKALKEEGFRVILVNSNPATIMTDPELADATYIEPITPEVVAKIIAK 80  
15790723     1 --MTEDSRTILLIGSGPIQIGQAAEFDYSGAQACRALQEEGARVVLVNSNPATIMTDPEMADAVYIEPIEPDAIAEVIEQ 78  
292656488   10 PQEGTEDRTILLIGSGPIQIGQAAEFDYSGAQACRALREEGARVVLVNSNPATIMTDPEMADKVYIEPITTEAISEIIER 89  
76802886     1 MPDED--RTILLIGSGPIQIGQAAEFDYSGAQACRALQEEGARVVLVNSNPATIMTDPEMADKVYVEPITTDAIAEVIRK 78  
222480136    1 ---MSEDRTILLIGSGPIQIGQAAEFDYSGAQACRALQEEGARVVLVNSNPATIMTDPETADRVYIEPITPEAISEVIRI 77  
257051158    1 -MTADDQPTILLIGSGPIQIGQAAEFDYSGAQACRALQEEGARVVLVNSNPATIMTDPEMADEVYLEPINTEAIAEIIRK 79  
284166554    8 EGETGDGRTILLIGSGPIQIGQAAEFDYSGAQACRALQEEGARVVLVNSNPATIMTDPEMADRVYIEPITTEAIAEIIRK 87  
289582218    6 DETPGDGRTILLIGSGPIQIGQAAEFDYSGAQACRALQEEGARVVLVNSNPATIMTDPEMADEVYIEPITTDAIAEIIRK 85  
300710620    5 DTVDGEQRTILLIGSGPIQIGQAAEFDYSGAQACRALQEEGVRVVLVNSNPATIMTDPEMADKVYIEPITTEAIAEIIEK 84  
110669189   17 ADTTSADRTILLIGSGPIQIGQAAEFDYSGAQACRALQEEGARVVLVNSNPATIMTDPEMADRVYIEPITTEAIAEIIRS 96  

13472276    81 ERPDALLPTMGGQTALNTALSLRRMGVLDRYNVEMIGADATAIDKAEDRALFREAMSKIGLETPKSMlanatdvknadrk 160 
15790723    79 EDPDGVIAGLGGQTGLNVTAALAEQGVLDEHDVDVMGTPLDTIYATEDRDLFRQRMADLGQPVPASTtialgddet---- 154 
292656488   90 ERPDGVIAGLGGQTGLNVTAELAEEGVLEKFDVDIMGTPLDTIYATEDRDLFRQRMEKIGQPVPKST------------- 156 
76802886    79 EDPDGVIAGLGGQTGLNVTAELAEEGVLDEHGVEIMGTPLDTIYATEDRDLFRERMKDIGEPVCRSE------------- 145 
222480136   78 EEPDGVIAGLGGQTGLNVTAELAEEGILEEYDVEVMGTPLDTIYATEDRDLFRQRMEGLGQPVPAST------------- 144 
257051158   80 EEPDGVIAGLGGQTGLNVTAELAEEGVLEEHDVDVMGTPLDTIYATEDREQFRKRMEKIGEPVPAST------------- 146 
284166554   88 EQPDGVIAGLGGQTGLNVTAELAEEGVLEEYDVDIMGTPLDTIYATEDRDLFRQRMEKIGQPVPKST------------- 154 
289582218   86 ENPDGVIAGLGGQTGLNVTAELAEEGILEEFDVEIMGTPLETIYATEDRDLFRQRMEKIGQPVPGST------------- 152 
300710620   85 ERPDGVIAGLGGQTGLNVTAELAEEGVLEEFDVEIMGTPLETIYATEDRDQFRERMEEIGQPMPRSR------------- 151 
110669189   97 EQPDGVIAGLGGQTGLNVTAELAEESVLETHNVEIMGTPLETIYATEDRDLFRQRMERIGQPVPQST------------- 163 

13472276   161 theaeraalkaekpdnldaeldaletrwnlgegdrkqryISHA--------------MAIAAQALDHV-G-LPAIIRPSF 224 
15790723   155 -------------------------------atdidegaLRER--------------VDDAVEAVG---G-LPVIARTTY 185 
292656488  157 ---------------------------------------TISLeegeaveniteealVERVEDSVDAV-GdLPVISRTTY 196 
76802886   146 ---------------------------------------TISS--------------MDEVEDAVESVgG-LPVIARTAY 171 
222480136  145 ---------------------------------------TISLdegesvtdfdeeafRGRVQAAVDEVgG-LPVIARTTY 184 
257051158  147 ---------------------------------------TIKS--------------MDEVEAAVEEVgG-LPVIMRTTY 172 
284166554  155 ---------------------------------------TISLeegeqvselteedlRERVEAAVEEVgG-LPVIARTTY 194 
289582218  153 ---------------------------------------TITLeegesatslseddlRERVEAAVDEVgG-LPVIARTTY 192 
300710620  152 ---------------------------------------TIES--------------VGEVEDAVEAVgG-LPVIMRTTY 177 
110669189  164 ---------------------------------------TISLtedeavqslteadlKDRVHEAVETVgG-LPVIARTTY 203 

13472276   225 TMGGTGGGIAYNRAEFYDIVQSGLDASPTTEVLIEESVLGWKEYEMEVVRDKADNCIIVCSIENIDPMGVHTGDSITVAP 304 
15790723   186 TLGGSGSGVVHDFEALVDRVRTGLRLSRNAEVLVTESITGWVELEYEVMRDAGDSCIIVCNMENIDPMGIHTGESTVVTP 265 
292656488  197 TLGGSGSGVVHEMDELVSRVRKGLRLSRNSEVLITESISGWVELEYEVMRDADDSCIIICNMENIDPMGIHTGESTVVTP 276 
76802886   172 TLGGSGSGVVDDMEELREIARKGFQLSRNHEVQITESIAGWVELEYEVMRDADDSCIIICNMENIDPMGIHTGESTVVTP 251 
222480136  185 TLGGSGSGVVDDFEELVERVRKGLRLSRNSEVLITESIAGWVELEYEVMRDADDSCIIICNMENIDPMGIHTGESTVVTP 264 
257051158  173 TLGGAGSGVIGDMDELKEATRKGLRLSRDDRVMITESIDGWIELEYEVMRDADDSCIIICNMENLDPMGIHTGESMVVTP 252 
284166554  195 TLGGSGSGVVHEFDELLARVRKGLRLSRNSEVLITESIAGWVEYEYEVMRDADDSCIIICNMENIDPMGIHTGESTVVTP 274 
289582218  193 TLGGSGSGVVEEMDELIERVRKGLRLSRNSEVLITESIAGWVEYEYEVMRDADDSCIIICNMENIDPMGIHTGESTVVTP 272 
300710620  178 TLGGSGSGVVEEMDELKESVRRGLRLSRNGEVLITESISGWVELEYEVMRDADDSCIIICNMENIDPMGIHTGESTVVTP 257 
110669189  204 TLGGSGSGVVAEMNELIERVRKGLRLSRNSEVLITESIAGWVELEYEVMRDADDSTIIICNMENLDPMGIHTGESIVVTP 283 

13472276   305 ALTLTDKEYQMMRNASIAVLREIGVEtGGSNVQFAVNPAD---GRLVVIEMNPRVSRSSALASKATGFPIAKIAAKLAVG 381 
15790723   266 SQIIPDDGHQEMRNAAVAVIRELGIQ-GGCNIQFAWRDDGtpgGEYRVVEVNPRVSRSSALASKATGYPIARVTAKVALG 344 
292656488  277 SQVIPDEGHQEMRDAALQVIRELGIQ-GGCNIQFAWHDDGtpgGEYRVVEVNPRVSRSSALASKATGYPIARVTAKVALG 355 
76802886   252 SQVIPDEAHQEMRNSALKVIRELGIE-GGCNIQHAWRDDGtpsGEYRVVEVNPRVSRSSALASKATGYPIARVTAKVAMG 330 
222480136  265 SQVIPDDGHQEMRDAALEVIRDLGIQ-GGCNIQFAWHDDGtpgGEYRVVEVNPRVSRSSALASKATGYPIARVTAKVALG 343 
257051158  253 SQVIPDEGHQEMRDTALKVIRELEIH-GGCNIQFAWRDDGspgGEYRVVEVNPRVSRSSALASKATGYPIARVTAKVAMG 331 
284166554  275 SQIVPDEGHQEMRTAALDVIRELGIQ-GGCNIQFAWHDDGtpgGEYRVVEVNPRVSRSSALASKATGYPIARVTAKVALG 353 
289582218  273 SQIVPDEGHQEMRTAALDVIRELGIQ-GGCNIQFAWHDDGtpgGEYRVVEVNPRVSRSSALASKATGYPIARVTAKVALG 351 
300710620  258 SQVIPDEGHQEMRSAALEVIRDLGIQ-GGCNIQFAWHDDGtpgGEYRVVEVNPRVSRSSALASKATGYPIARVTAKVALG 336 
110669189  284 SQVIPDEGHQAMRDAALDVIRELGIQ-GGCNIQFAWHDDGtpgGEYRVVEVNPRVSRSSALASKATGYPIARVTAKVALG 362 

13472276   382 YTLDELENDITgGATPASFEPSIDYVVTKIPRFAFEKFPGAEPVLTTAMKSVGEVMAIGRTFQESLQKALRGLETG-LTG 460 
15790723   345 KRLHEIDNEIT-GQTTAAFEPAIDYVVTKVPRWPNDKFPEVDFELSTAMKSTGEAMAIGRTFEESLLKALRSSEYDpSVD 423 
292656488  356 KRLHEITNEIT-GETTAAFEPAIDYVVTKVPRWPKDKFTDVDFELSTAMKSTGEAMSIGRTFEESLLKALRSSEYD-PAA 433 
76802886   331 KRLHEIENEIT-GETTAAFEPAIDYVVTKVPRWPKDKFSDVEFELGPAMKSTGEAMSIGRTFEESLLKALRSSEYDpAVD 409 
222480136  344 KRLPEIDNEIT-GETTAAFEPAIDYVVTKVPRWPIDKFDDVDFELGTAMKSTGEAMAIGRNFEESLLKSLRSSEYDpAVD 422 
257051158  332 KRLHEIENEIT-GETTAAFEPAIDYVVTKIPRWPIDKFRDVDFELGPAMKSTGEAMSIGRTFEESLLKALRSTEYDpAVN 410 
284166554  354 KRLHEIENEIT-GETTAAFEPAIDYVVTKVPRWPKDKFDDVDFELTTAMKSTGEAMAIGRTFEESLLKALRSSEYEpDVD 432 
289582218  352 KRLHEIDNEIT-GETTAAFEPAIDYVVTKVPRWPKDKFDDVDFELTTAMKSTGEAMAIGRSFEESLLKALRSSEYEpDVA 430 
300710620  337 KRLHEIENEIT-GETTAAFEPAIDYVVTKVPRWPKDKFDEVEFKLGTAMKSTGEAMSIGRTFEESLLKALRSTEYVpDVD 415 
110669189  363 KRLHEINNEIT-GETTAAFEPAIDYIVTKVPRWPKDKFDNVDFELSTAMKSTGEAMAIGRTFEESLLKALRSSEYDpAAN 441 

13472276   461 LDEieipglghgatvanhADDRNAIRA-ALGTPTPDRLRMVAQAIRMGTSLEDVHAMCKIDPWFLEQIAGILAMEARIRE 539 
15790723   424 WAT----------------VSDDELAAdYLQRPSPDRPYAVFEAFERGFTVGDVNDHTGFREWYLQRFQNVAAASAAASE 487 
292656488  434 DWDe--------------VSDEELEAE-YLETPTPDRPYAIFEAFERGYTTEDVVELTDIHEWYVERFGRVVEAVEAAAE 498 
76802886   410 WSE----------------VDDDELAAdYLETPTPDRPYAIFEAFDRGYTVDEIHDLTGIYDWYLERFGRIAEAADAAQD 473 
222480136  423 WPA----------------IDDETLETeYLERPTPDRPYAIFEAFDRGYTVADVEDLTGIKPWYLERFKRVSDSAQAAQN 486 
257051158  411 WT----------------EVSDDELESeYLVRPSPDRPYAMFEAFERGYSVETVSELTEIREWYVERYKRIADAADAA-- 472 
284166554  433 WAE----------------VSDEELEEqYLERPSPDRPYAMFEAYERGYTVDEVVELTGIFEWYAERFKRIADSSLAAQE 496 
289582218  431 WAD---------------VSDEELESH-YLERPSPDRPYAMFEAFERGYSVEEVVSLTGIFEWYTERYSRIAESVRAAQE 494 
300710620  416 WGT----------------LSDEDLEEgYLETPSPDRPYGMFEAFSRGYSVEEICELTGIYEWYVERYETIASAADAAQN 479 
110669189  442 LET----------------LSDETLKSeYLSRPTPDRAYAIFEAFDREYTVDTVAELTGIKQWYLKRFQRVPTALKTA-- 503 

13472276   540 HGipqDAVNLRMLKAMGFSDARLASLT------------------------------------R-T-------------- 568 
15790723   488 GD-------VATPAALGYTNSAVAALAsd---------------------------------gGdV-------------- 513 
292656488  499 GD-------FAAAASAGHTNASIAAa------------------------------------tG-T-------------- 520 
76802886   474 GD-------FQAAADKGFTNQEITAIA------------------------------------G-Gefndthaswipsev 509 
222480136  487 GE-------FAQAATAGHTNADIAALD--------------------------------------G-------------- 507 
257051158  473 -----SAGELDIAAEAGFTNHEVATLAsggafddthaswlpdrlldergvvsddgeatpqtdgGgV-------------- 533 
284166554  497 GD-------FTEAAIAGHTNASIAATA------------------------------------G-A-------------- 518 
289582218  495 GD-------FTEAAIAGHTNASIATTA------------------------------------G-T-------------- 516 
300710620  480 GE-------FGEAAEIGFTNAQVAAGIdaseast-----------------------ipqadgG---------------- 513 
110669189  504 -----EEGELTAAATTGVTNTEIAETT------------------------------------E-K-------------- 527 

13472276   569 -------------DAEVV--TKIREKLDVH-PV--YKRIDTCAAEFASPTAYMYSTY--------------------Evp 610 
15790723   514 -------------AVDDV--AATA-------PErtFKQVDTCAGEFAASTPYYYSAR----------------------- 548 
292656488  521 -------------SVGEV--EQNVP----G-RT--YKQVDTCAGEFAAQTPYYYSARkpeffrg------pfegdsaG-- 570 
76802886   510 readeedgqqvetDGAGV--TIDDVDTETSdRT--FKQVDTCAGEFRASTPYYYSAReppt------------------- 566 
222480136  508 -------------GVDVetveEDV-------PGrtYKQVDTCAGEFAAETPYYYSAR--------------------Qse 547 
257051158  534 -------------SVADV--EDAA-------PArsFKQVDTCAGEFEASTPYYYSARepls------------------- 572 
284166554  519 -------------DVDTV--EQEV-------PGrtYKQVDTCAGEFEAETPYYYSARk------------------nEye 558 
289582218  517 -------------DVGSV--EQEV-------PGrtYKQVDTCAGEFEAETPYYYSARqnefesgplegqaaagelevD-- 572 
300710620  514 -------------AIDAV--EASA-------PErdFKQVDTCAGEFAASTPYYYSARargdr------------------ 553 
110669189  528 -------------TIDAV--EKTV-------PGrtYKQVDTCAGEFAAQTPYYYSSRkpeft------------------ 567 

13472276   611 fagalaNEAQ----VS------SRK--KVVILGGGPNRIGQGIEFDYCCCHAAFALRDAGYEAIMINCNPETVSTDYDTS 678 
15790723   549 ------SQGS-----TgsdvraDRDahSVVIVGGGPIRIGQGVEFDYCTVHAVRALREAGIDAHVVNNNPETVSTDYDTS 617 
292656488  571 ------NELR----VDr-----DME--SVVVVGGGPIRIGQGVEFDYCSVHAVQALRDMGIDAHVVNNNPETVSTDYDTS 633 
76802886   567 --gqgaSEVQ----V-------DREaeSVVVVGGGPIRIGQGVEFDYCAVHAVRALREEGIDAHVVNNNPETVSTDYDTS 633 
222480136  548 fnrgplKGDA-----AagelvvDKSvdSVVVVGGGPIRIGQGVEFDYCSVHAIQALRELGIEAHVVNNNPETVSTDYDTS 622 
257051158  573 --glerNE-Vqv-dP-------EIE--SVVVVGGGPIRIGQGVEFDYCSVHAVRALEEIGIDAHVVNNNPETVSTDYDTS 639 
284166554  559 kgpllgDAASgeleV-------DRDleSVIVVGGGPIRIGQGVEFDYCSVHAVQALRDMGIEAHVVNNNPETVSTDYDTS 631 
289582218  573 ------PEIE-----------------SVIVVGGGPIRIGQGVEFDYCSVHAVRALRELGIDAHVVNNNPETVSTDYDTS 629 
300710620  554 -lgrdeVQVD-----T------DAE--SVVIVGGGPIRIGQGVEFDYCTVHAVQALRENGIEAHVVNNNPETVSTDYDTS 619 
110669189  568 -sgsgpYEGA----AAagelrvDRDieSVVVVGGGPIRIGQGVEFDYCSVHAVRALRELGIDAHVINNNPETVSTDYDTS 642 

13472276   679 DRLYFDPLTAEDVLEILRAEQAsgelLGVIVQFGGQTPLKLADALEK----A------GI--P--ILGTSPDMIDLAEDR 744 
15790723   618 DGLFFEPITAEEVADVVEATNA----DGVMVQFGGQTSVDVGAPLEAelerR------GL--DceIMGTDVDAMDLAEDR 685 
292656488  634 DGLFFEPITAEEVADVIEAIDA----DGVMLQFGGQTSVNIGHPLES----EldrrgvDC--E--ILGTTIDAMDLAEDR 701 
76802886   634 DGLFFEPITAEEVADIIEETDA----DGVMVQFGGQTSVNVGEPLEDelerR------GL--DcdIMGTSVEAMDLAEDR 701 
222480136  623 DGLFFDPITAEEVADVVEATGA----DGVMVQFGGQTSVNIGEPLEAe--lQ------RRglDceIMGTSVEAMDLAEDR 690 
257051158  640 DGLFFEPITAEEVADVVEETGA----DGVMVQFGGQTSVDIGHPLEAeldrR------GLdcE--VMGTSVDAMDLAEDR 707 
284166554  632 DGLFFEPITAEEVADVAEATGA----DGVMVQFGGQTSVNIGEPLEDelerR------GL--DctVMGTSVEAMDLAEDR 699 
289582218  630 DGLFFEPITAEEVADVAEATGA----DGVMVQFGGQTSVNIGEPLEDelhrR------GL--DceVMGTSVEAMDLAEDR 697 
300710620  620 DGLFFEPITAEEVADVIEATGA----DGAMIQFGGQTSVDIGEPLEQ----EierrglDC--E--IMGTAVDAMDLAEDR 687 
110669189  643 DGLFFEPITAEEVADVAEATNA----DGVMVQFGGQTSVNIGHPLET----EldrrglDC--D--ILGTSVDAMDLAEDR 710 

13472276   745 DRFQKLLHKLGLSQPKNGIAYSVEQARLVAGELGFPLVVRPSYVLGGRAMQIIHDESMLQSYLLDTVpglvpedikqkyp 824 
15790723   686 DRFNRLLDERDISQPDGGSATSVAGALELAAEVGYPVLVRPSYVLGGRAMEIVHDDDELRRYVEEAV------------- 752 
292656488  702 DRFNRLMDDLGILQPEGGSATSEEEALDLANDLGYPVLVRPSYVLGGRAMEIVHSDADLKEYIEEAV------------- 768 
76802886   702 DRFNALMDELGISQPEGGTATSKAEALDLAHDIGYPVLVRPSYVLGGRAMDVVYSDAELEEYIEEAV------------- 768 
222480136  691 DRFNVLMDEMGIAQPKGGTATSESEALELAHDLGYPVLVRPSYVLGGRAMRVVEDDAELEEYIEEAV------------- 757 
257051158  708 DRFNRLMDDLGIAQAEGGTATSEAEALELARDIGYPVLVRPSYVLGGRAMEVVYNDDDLKTYIEEAV------------- 774 
284166554  700 DRFNALMDDLGIAQPEGGAAHSKEEAMQLAHEIGYPVLVRPSYVLGGRAMDVVYDDAELETYIEEAV------------- 766 
289582218  698 DRFNALMDELEIAQPEGGTAFSKEEALELAHDIGYPVLVRPSYVLGGRAMDVVYTDEELETYIEEAV------------- 764 
300710620  688 DRFNGLMDELGIAQPEGGTATSEAEALDLAHEIGYPVLVRPSYVLGGRAMEVVHSDSELEEYIEEAV------------- 754 
110669189  711 DRFNRLMSSLDIKQPVGGSATSEPEALTLANDLGYPVLVRPSYVLGGRAMDVVHSDVELQEYIEEAV------------- 777 

13472276   825 ndktgqinTLLGKNPLLFDTYLSGAIEVDVDCLCDGKATFVSGILEHIEEAGIHSGDSACSLPV-HSLPSELVDELERQT 903 
15790723   753 --------RVSPEKPVLVDEFLADAVELDVDAVSDGEDVLVGGVMEHIESAGVHSGDSACVIPP-RGLGDDILARVREVT 823 
292656488  769 --------RVSPDKPILIDEFLADGVELDVDAVSDGEDVLIGGVMEHVETAGVHSGDSACMIPP-RSLDDETMARVREVT 839 
76802886   769 --------RVSPDKPILVDDFLADAVELDVDAVSDGEDVIIGGIMEHVEAAGVHSGDSACMIPP-RSLSQDVLERVREVT 839 
222480136  758 --------RVSPDKPILVDQFLDDAVELDVDAVADGDDVLLGGVMEHVESAGVHSGDSACMIPP-RSLGEETLARVREVT 828 
257051158  775 --------RVSPDKPILVDDFLADAIELDVDAVADGDDILIGGVMEHVETAGVHSGDSACMIPPrSDEIENVMPRIREVT 846 
284166554  767 --------RVSPDKPILVDDFLEDAVELDVDAVADGEDVLIGGVMEHVEAAGVHSGDSACMIPP-RSLDDETLERVREVT 837 
289582218  765 --------RVSPEKPILVDDFLENAVELDVDAVSDGRNVLIGGIMEHVESAGVHSGDSACMIPP-RSLDDDTLARVREVT 835 
300710620  755 --------RVAPDKPILVDKFLEGGVELDVDAVSDGERVLIGGIMEHVESAGVHSGDSACMIPP-RWLEADAMGRIREVV 825 
110669189  778 --------RVSPDKPILIDQFLADAIELDVDAVADGERTIIGGVMEHVESAGVHSGDSACMIPP-RSLSAETMARVRTVT 848 

13472276   904 AALARALNVGGLMNVQYAIK-----D--------GTVYVLEVNPRASRTVPFVAKTIGRPIAKIAARIMAGE-TLEDAFA 969 
15790723   824 TEIARALDTVGLLNVQLAVQ-----D--------GEVYVLEANPRSSRTVPFVSKATGVPIAKLAAKVMAGE-SLADLDA 889 
292656488  840 EDIASALDTVGLMNVQLAVKrnedgS--------NDVYVLEANPRSSRTVPFVSKATGVPIAKLAAKVMAGN-SLADLDV 910 
76802886   840 LDIARGLDTVGLLNVQLAVR-----D--------GEVFVLEANPRSSRTVPFVSKATGVPIAKLAAKVMAGQ-SLEELAA 905 
222480136  829 EDIARALDTVGLLNVQLAVT-----GvgdddaesE-VYVLEANPRSSRTVPFVSKSTGVPIAKLAAKVMTDDlTLADLDV 902 
257051158  847 EQIAGALETVGLMNVQLAVR-----D--------GEVYVLEANPRSSRTVPFVSKATGVPIAKLAAKVMAGA-NLDELDV 912 
284166554  838 EDIATALDTVGLLNVQLAVR-----D--------GEVYVLEANPRSSRTVPFISKATGVPIAKIAAKVMAGE-TLADLAI 903 
289582218  836 EDIAEALKTKGLMNVQLAVQ-----D--------GEVYVLEANPRSSRTVPFVSKATGVPIAKLAAKVMAGE-TLSSLEA 901 
300710620  826 EQIARALDTVGLLNVQLAVY-----E--------GEVYVLEANPRSSRTVPFVSKATGVPIAKLAARVMAGA-SLDDLDA 891 
110669189  849 EDIATALDTVGLLNVQLAIK-----D--------DEVYVLEANPRSSRTVPFVSKATGVPIAKLAAKVMAGE-SLTTLDV 914 

13472276   970 HY-GAMPdprnpGHIAVKEAVFPFARFPGVDILLGPEMRSTGEVMGLDRDFALAFAKSQLGA-GVDLPRSGTLFVSVR-- 1045
15790723   890 SE--GVP-----EQYSVKEVVLPFDRLPGSDPRLGPEMKSTGEVMGTASDPGMAYWKAQVAAsNAPVPGS---------- 952 
292656488  911 SEqIP-------EQVSVKEVVLPFDRLPGSDPRLGPEMKSTGEVMGTATSFGKAYEKAQSAA-NDPVPADGTVYVDLA-- 980 
76802886   906 EE--QIP-----EHVSVKEVVLPFDRLPGSDPRLGPEMKSTGEVMGTARSLGKAYQKAQSAT-GTPLPTAGTALVDLEtl 977 
222480136  903 DE--QIP-----EHRSVKEVVLPFDRLPGSDPRLGPEMKSTGEVMGTARSFGKAYDKAQDST-NKPIPESGTAVVDLSad 974 
257051158  913 AEq-qPE------QVSVKEVVLPFDRLPGSDPRLGPEMKSTGEVMGTAGSFGKAYQKAQMAV-DKPIPLSGTAIVDLP-- 982 
284166554  904 EE--QIP-----EQTSIKEVVLPFDRLPGSDPRLGPEMKSTGEVMGSADTFGKAYDKAQDAT-NKPIPESGTAIIDLSad 975 
289582218  902 TE--QVP-----DHTSIKEVVLPFDRLPGSDPRLGPEMKSTGEVMGTASDFGTAYWKAQQAA-YNAVSE-GTAVVDF--- 969 
300710620  892 SE-Gi------pEQTSVKEVVLPFDRLPGSDPRLGPEMKSTGEVMGTADSFGKAYWKAQQAA-GAVLPRGGTAVIDL--- 960 
110669189  915 TE--QIP-----AETSVKEVVLPFDRLPGSDPRLGPEMKSTGEVMGTAATFGKAYDKAQHSV-GKPIPSSGTAWVDLS-- 984 

13472276  1046 --DEDK-----------KGILPAVKRLAGLGFKVLATSGTQRFLAENG-VV-AEKINKVLE--GRPHIEDAIRNRQVQIV 1108
15790723   953 -----------------TAVVDLLVEGLGERFEVVTVKD----------------------------VPAAIRRGEVEFL 987 
292656488  981 --DPEF-----------PDADSEAGQELLDAFN--------------E-YY-EVLTPDDVDd-----FLTMLREGDFDFV 1026
76802886   978 ggMSQQ-----------DEDITDIREGAERHYEVTTPDDY-------------------------DDLTGALRDGDIDII 1021
222480136  975 efPDPDteageslvagyAEHFELSEAT-------------D--------------------------LIEAAKRGEIDLI 1015
257051158  983 -------------------IVGFEEHFETLDLDDFDSQAE---------------------------LEAALRDGEIDLV 1016
284166554  976 kfPDPE---------------------TEEGEALV--DGFTEYFDLCEeVD----------------LAQAVREGKVDLI 1016
289582218  970 --DVDG---------------------FETHFEIAEFDD----------------------------VPQAIREGEVDFV 998 
300710620  961 --DVDG-------------------------------------------FDeFYEIREFED------VPEAIREGKVDLV 989 
110669189  985 --DEEF----------------------------PAPDSNDGAALRDG-YDaCFELVTFSEddDADTLINALRQGEIDIV 1033

13472276  1109 FNTTDG-QkavsDSKSLRRATLMQKVPYYTTLSGAAAVAEAIAALKagsleVRPLQEYF 1166
15790723   988 VS----------DDRDALTAAVEAEIPYVSTVAAAEAMREGIAAADga-reAMPVADRP 1035
292656488 1027 VSRDRD----------TLIDCVEEEVSYFSTYASAKAALEARGAADed-idVLPVGERP 1074
76802886  1022 FSRDRD----------TLEVAVEEEIAYLSTVPSSRATIEAIETKDep-ldVMALSERP 1069
222480136 1016 VSRQRE----------LLEVAVEEEITYFSTHASAKAALEAIdhkg-ddldVMAVSDRP 1063
257051158 1017 ISRNRD----------VLEVCVEESTTYFSTIASGKAALEAIESDDqp-lsVQDVATRP 1064
284166554 1017 VSRDRD----------LLEVAVEEEITYFSTPASASAALEALEAKDep-idVQAITDRP 1064
289582218  999 VSRDRD--------SL--EMAVEEEIPYLSTEASAEAYVEALDAFEge-leVDSISERP 1046
300710620  990 ITRDREsL----------QTAVEEDVTYYSTAPSVQAALEALRARDdp-ldVRAVSDRP 1037
110669189 1034 ISRDRDpL----------EVCVEEEITYFSTTASAFAALEAIDSKNd----PIDIDPVS 1078
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