Conserved Protein Domain Family
DEPP
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pfam15343: DEPP (this model, PSSM-Id:405928 is obsolete and has been replaced by 464661)
Decidual protein induced by progesterone family
DEPP is a family of proteins expressed in various tissues, including pancreas, placenta, ovary, testis and kidney. High levels are found during the first trimester. Its expression is induced by progesterone, testosterone and, to a much lower extent, oestrogen. The family is alternatively known as fasting-induced gene protein, FIG.
Links
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Statistics
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PSSM-Id: 405928
Aligned: 13 rows
Threshold Bit Score: 252.054
Created: 27-Apr-2021
Updated: 29-Sep-2021
Structure
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Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
EGW13503      29 QEEPPNSPSLDDYVRSICQLAQPTSVLDKI--RSRPHRPYRP-------------AWTREKRCQAESVADSSPCFSSLQP 93  Chinese hamster
2_pfamImport   4 QSDLLSSQSLDDYVKSICQLAQPTSVLDGDq-RLPYNRLRKPcr---------lrASHSEKSSPASPMQDITAHFSGQHS 73 
Q5BMD4        28 GQEPPASPSLDDYVRCICQLAQPTSVLDKAtaWSPPNRSCRP-------------AWPREKRHQSESLEDSSPCFSSLQP 94  Norway rat
XP_002722573  29 GQEPPASPSLDDYVRSICQLAQPTCVLDKAtvQDGLSGPHRP-------------AWGLEETCPTATLQDSTARFGAQQP 95  rabbit
1_pfamImport   4 GQDPPASPSLDDYVRSICQLAQPTSLLDKVtaRSRPSRPHRS-------------PRSSEKSHPAASLQDNTASFGGQQS 70 
Q5RBE4        28 GQEPPPSPSLDDYVRSISRLAQPTSVLDKAtaQGQPRPPHRP-------------AQACRKGRPAVSLRDITARFSGQQP 94  Sumatran orangutan
XP_006097602  28 RQDPLASPSLDDYRRSICQLAQPTSALTEAaaRAQPSRRPWQ-------------ARAGEKSGSPGSLQDFTTPFSSQQP 94  little brown bat
XP_534951     28 GQEPPASPSLDDYVKSICQLAQPTSVLDMAtaRAQPSRTLRP-------------AQAFKKNCPTESLQDITTHFSGQQP 94  dog
AES10692      28 GQEPPASPSLDDYVKSICQLAQPTSVLDVAtvRAQPGRTPRP-------------ARAFRKSPPTESLQDITTRFSGQQP 94  domestic ferret
XP_003359328  28 GEEPPASPSLDDYVRSICQLAQPTSVLDEAaaWARPRRPHRP-------------GRSCEKSRSDGSLQDITTHFSGQQP 94  pig
Q1RMP5        28 GEEPPASPSLDDYVRSICQLAQPTSVLDEAaaRVRTSRPHRI-------------ARSCAKSCPTGSLQDITTRFTGQQP 94  cattle
XP_010587595  26 GPEPPPSPSLDDYVRSICQLAQPASVLDEApaGDRPSRLHRP-------------ARACERSHPAMSLQDIPTCFSGQGP 92  African savanna...
XP_007478166  35 QSDLLSSQSLDDYVKSICQLAQPTSVLDGAq-RLPYTRPWRPcklrgktfndaslASHSEKSCPTSSLQDITARFSGQNL 113 gray short-tail...

EGW13503      94 PLPSPGTDNPLDWLFGKSQEQQADRRDLPNGPD-SSDHWGVHRQMEEN------RGRLCEARLPENSPGRKSGHRQQTSD 166 Chinese hamster
2_pfamImport  74 TLPLGNNIDPLDWLFGESQPKRQSWKDTLRRTGlSTDPSCLHKQNEPGksrvprRIRACEAKLPGGPLTKLSSEWGKVWE 153
Q5BMD4        95 TLPAPGTDNPLDWLFGKSQEQQTDRRDLPNRTG-SSGHWGVHRQMGKD------SGRPSEARVPEYSLGRKPGHRHQTSN 167 Norway rat
XP_002722573  96 PRPTAGPADPLDWLFGESQEKQSSRRQPARRTGaSAGLGGLHRQTDSGktravpRGKLCEARAPGHSLARTSRDGPQSAN 175 rabbit
1_pfamImport  71 TLPSAGTTDPLDWIFGESQRNETNRRDLLRRTGpSAGHWRAHREANSG------KRRLFEARAFGHSLTRPSQDVHQSSN 144
Q5RBE4        95 TLPMADTVDPLDWLFGESQEKQPSQRDLPRRTGpSAGLWGPHRQMDSSkpmgapRGRLCEARMPGHSLARPPQDGQQSSD 174 Sumatran orangutan
XP_006097602  95 P----NTADPLNWLFGQSQEKQPRRRDLPRRTGpSADPWGPHREMESTkaggcpRGKLYDARAPGHCPVGQLRDWHQGS- 169 little brown bat
XP_534951     95 APTRDCTADPLDWLFGDSQEKQPSRRDPPRTTGsSADPWGPHRQMDGGkaqgtsRGRFCDASVQEHSLVRPSRDWHQCS- 173 dog
AES10692      95 ALPGDGTADPLDWLFGESQEKRSSRRDQPRRTGsSADSWGPHKQMDCGkargtpRGRPWDARVQGHPLARPSRDWHQGS- 173 domestic ferret
XP_003359328  95 VLPRAGPADPLDWLFGESQEKRPSRRDLPRRTGlPADPQALRKETNSGkaqggpKGRLCEARAPEHSLERPLRNWHQCS- 173 pig
Q1RMP5        95 SLPRTGTVDPLDWLFGESQEKQPSKRDVPRRTGpSADPWASRRQTDSGkapgtpRGRLSDAKAPGHSLQRTSRDWHQCS- 173 cattle
XP_010587595  93 LLPRVGTADPLDWLFGESQEKQPTRKDLLRRTGlSANPWGLHRQTDTGkarsgpKARFCDARAPGHSLARLPQGRHLSS- 171 African savanna...
XP_007478166 114 TLPLGNNTDPLDWLFGESQTKRQSWKDALRRTGsATDPSPLHKQTETGksrvarRVRACEAKVSGGPLGKLSTD--KALE 191 gray short-tail...

EGW13503     167 RKSWTSRKSHQALAAVSGSRPSs-ILSTLCLHLPVIHEL 204 Chinese hamster
2_pfamImport 154 KRTQPSMLNASLKYSSSSHQDR--ISRVLNSNLPVIYEL 190
Q5BMD4       168 LKSWTSRKPCQALASVSSSRPSs-ILGTLYLHLPVIHEL 205 Norway rat
XP_002722573 176 LRSHMAGRPSRATDSSYSPRPSs-ILRTFYLHLPVIHEL 213 rabbit
1_pfamImport 145 LNNWASGQPGRATASPCNPRPSs-ILRSLYLHLPVIHEL 182
Q5RBE4       175 LRSWTFGQSAQAMASRHRPRPSs-VLRTLYSHLPVIHEL 212 Sumatran orangutan
XP_006097602 170 ---RASRQPIRAAAPPPSSRPSs-VLRTLYLHLPVIHEL 204 little brown bat
XP_534951    174 ---WASRQFSGAAASPPAPRPSs-TLRTLYVHLPVIHEL 208 dog
AES10692     174 ---WASRQLCTDVASPPAPRPRs-TLRTLYLHLPVIHEL 208 domestic ferret
XP_003359328 174 ---PASVQPGRDAASSTSPRRSs-ILRTLYLHLPVIHEL 208 pig
Q1RMP5       174 ---QASGQPGQDAGSPTSPRHSs-ILRTLSLHLPVIHEL 208 cattle
XP_010587595 172 --SWDSRQ----------PRSSgsVLRALHSDLPVIHEL 198 African savanna elephant
XP_007478166 192 KRTQPSALNAALEYSSNSHQGR--IPRSLNSNLPVIYEL 228 gray short-tailed opossum
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