1EUU,1D7P,1CZT,1GOF


Conserved Protein Domain Family
FA58C

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cd00057: FA58C 
Click on image for an interactive view with Cn3D
Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
Statistics
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PSSM-Id: 238014
Aligned: 26 rows
Threshold Bit Score: 92.03
Created: 7-May-2001
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
 
sugar binding
Conserved site includes 3 residues -Click on image for an interactive view with Cn3D
Feature 1:sugar binding site [chemical binding site]
Evidence:
  • Structure:1EUU; galactose binding domain
  • Citation:PMID 8591030
  • Comment:potentially binds different sugars in other proteins

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Feature 1                                                   #                                # 
1EUU       460 GLLDQar-----mSIaDVDSEETareDGRASNViDGNp---sTFWHTewsradapgyPHRISLDLGGTHTISGLQYTRRq 531  Micromonospora v...
1GOF         7 SAISRnn-----wAV-TCDSAQS---GNECNKAiDGNk---dTFWHTfygangdpkpPHTYTIDMKTTQNVNGLSMLPRq 74   Hypomyces rosellus
P97846      29 ELVGPly----arSL-GASSYYGl--FTTARFA-RLHg---iSGWSPrig-----dpNPWLQIDLMKKHRIRAVATQGAf 92   Norway rat
729008      33 YALGMqdrtipdsDI-SASSSWSd--STAARHS-RLEssdgdGAWCPagsv--fpkeEEYLQVDLQRLHLVALVGTQGRh 106  human
7503664    944 EDVGIvsgf-vpdGA-FADNSDStnlGYEPHHA-RMGs----SGWCGak------edFIFLSVDLQRIYTLTTLRIAGVa 1010 Caenorhabditis e...
1841872    664 NPHSTsk-----iKI-TSSSIDK---GNLYDIV-ELTp---nAFWTKdv-------pASWVMIDLGPNRTVVPMYYTIRh 723  Dictyostelium di...
1346296   1118 EPLGLigel-pleNI-QVSSNSE---EKDYLSI-NGN-----RGWKPly------ntPGWVMFDFTGPRNITGILTKGGn 1180 domestic silkworm
11356716   175 GESSVdla--agrRL-TASSSTG---AYTPGNGnDGNr---aTYWESann-----alPQWLQADLGSARRVNRVVLRLPd 240  Streptomyces liv...
11356716    34 TAAGGpni--avgDA-TAASSSHg--EYGAANItDGNq---gTYWQSggg-----slPQWVQTDLGATERIDEVVLRLPa 100  Streptomyces liv...
1169346     18 LRSSTdyn--adhGV-KNSILNFs-nSKDASRF-DGS-----ESWSSsvld---knqFIVAGSDSVKHFVAISTQGRGDh 84   Dictyostelium di...
Feature 1            #                                                                         
1EUU       532 ns--anEQVADYEIYTSLN--GTTWDgpv-------asGRFTTs-lAPQRAVFpa-rdARYIRLVALSEQtgh-kyAAVa 597  Micromonospora v...
1GOF        75 dg-nqnGWIGRHEVYLSSD--GTNWGspv-------asGSWFAd-sTTKYSNFet-rpARYVRLVAITEAngq-pwTSIa 141  Hypomyces rosellus
P97846      93 n---swDWVTRYMLLYGDR--VDSWTpfyqq--ghnatFFGNVndsAVVRHDLhyhftARYIRIVPLAWNpr--gkIGL- 162  Norway rat
729008     107 agglgkEFSRSYRLRYSRD--GRRWMgwkdr--wgqevISGNEdpeGVVLKDLgppmvARLVRFYPRADRvm---sVCL- 178  human
7503664   1011 gsghlkGHVTKFQLFYKTEnqHTHKPypve-----fesPAGNHn--AMHHFDLkfplrARYILFGVTEYEg----nPCM- 1078 Caenorhabditis e...
1841872    724 glsyksDSLRTWDFQGSTN--GEQWTvlkrhtndpslnYKYATh-sWPVTGCEt---aFRYFRILQTGKNsnnrnfLVIg 797  Dictyostelium di...
1346296   1181 -----dGWVTSYKVLYTSD--FETFNpvidkd-gkekiFPANFdgiVSVTNEFhppirARYLKVLPQKWNk----nIEL- 1247 domestic silkworm
11356716   241 g---wpARSQTLKIQASDN--GSDFTdlta-----akaYTFDAaggQSATVTFda-atARYVRVLVTANTgq--paAQIs 307  Streptomyces liv...
11356716   101 g---weSRDQTLSVQGSAD--GTGFStlkt-----satYAFDPgsgNTVTIAFpa-tqTRFVRVDITANTgw--qaAQLs 167  Streptomyces liv...
1169346     85 -----dQWVTSYKLRYTLD--NVNWVeynn-----geiINANKdrnSIVTINFnppikARSIAIHPQTYNn----hISL- 147  Dictyostelium di...
Feature 1            
1EUU       598 ELEVEG 603  Micromonospora viridifaciens
1GOF       142 EINVFQ 147  Hypomyces rosellus
P97846     163 RLGIYG 168  Norway rat
729008     179 RVELYG 184  human
7503664   1079 KFDLMG 1084 Caenorhabditis elegans
1841872    798 GLEIYG 803  Dictyostelium discoideum
1346296   1248 RIEPIG 1253 domestic silkworm
11356716   308 ELEVYG 313  Streptomyces lividans
11356716   168 ELEVHA 173  Streptomyces lividans
1169346    148 RWELYA 153  Dictyostelium discoideum

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