A7TST2 37 LQAMDYVLDDRAEEGLALLKknEAedgSDQ-TIN-VLARGVIEFLEATLGFEAEEMKKASETLAKAENLSLKSRQYAQKN 114 Vanderwaltozyma polys... Q8VE09 31 LAGINMLLNNGFRESDQLFK--QY---RNHsPLM-SFGASFVSFLNAMMTFEEEKMQLACDDLKTTEKLCE--SEEAGVI 102 house mouse Q16TQ6 18 KQGIALWLNNQPKAAEESFN-------NREsSVHiVAGHTFISFMNAVISWETEKMNEAQGLLRELEKKCA--GDIGWIK 88 yellow fever mosquito O94699 16 IQGLNDILDDKMDEATEKFK-------SGNsSFH-LSGQAVVAFIQAVLTFEPSRFKDSQNRIDIAIKALSADKDDASKN 87 Schizosaccharomyces p... A1CQ80 28 RDPATLILNDDVDGAEDGLa-------EGTsSFH-NLGRGVVAFIRATLGFEQDIMRQASERLNEAETTASVDQHRAQHN 99 Aspergillus clavatus ... A2QQE8 32 MRAATLILNDDVDGAEDGLs-------EGTsSFH-NLGRGVVAFIRATLGFEQEIMRQASERLNAAETSAANDQHRAQHN 103 Aspergillus niger CBS... Q6CG79 33 LAAIDTVMDERKEDAAPYLSi------KTNsGLH-KLVHGVVGSIEAFFGQDPEQIRQTADHLATCETAAYKNIDRTHNY 105 Yarrowia lipolytica Q6CSC1 39 LQAMDYVLDDNAEVGLKLLAdnQAtspGDA-TVG-ALAKGVIEFLEATLGFEPEVMKKASTTLAEAEQLSLKSRAKLQKL 116 Kluyveromyces lactis ... Q0VF76 69 TTGLYLFLNNRFSDAINLIH--PW---SKNsSYH-ALIYSMFMVVKAILTFEPQDIQIGMNAAKEALKTCNNFRKKPRIV 142 house mouse Q28DB0 40 TLALNLFLNNKFSEALEILR--PW---AKEsIYH-ALGYSTILVMQSAMTFEPQDVQMGISTMKEALQTCQRFRKRTTVV 113 tropical clawed frog
A7TST2 115 Dlk--------ssS----LYAPGTVYAVTYTESCLLHALLMI-FSESYVETAKALLKLRKAYYMLQEIFEEMKKVKqtng 181 Vanderwaltozyma polys... Q8VE09 103 EtiknkikknvdarkstpsmvdRLQRQIIIADCQVYLAVLSF-VKQELSAYIKGGWILRKAWKIYSKCYVDINALQelyq 181 house mouse Q16TQ6 89 Tvrtklfgsy----epqktlasALEEQIILADTQLCLAILVS-LSQDIGGFVKGGWLLRKAWKVYQHTYSQIYQLYtktl 163 yellow fever mosquito O94699 88 Ntf---------lS----TFDPGVEYRVSIGLMLLLSALIGF-CSESIVTSVKSVYKLRKAHSIFSKINKRHFDHFsaaf 153 Schizosaccharomyces p... A1CQ80 100 Sqapn----tyhsA----MYTPGTEFALCQAMAQLMGAVVGV-LNESLTESIKGFYRLRKAYITLDAILKMEQKYLqesr 170 Aspergillus clavatus ... A2QQE8 104 Shapn----tyhsQ----IYAPGTEFALCQAMAQLMSAVVGV-LNESLTESIKGFYRLRKAYITLDAILKMEQKFImqar 174 Aspergillus niger CBS... Q6CG79 106 Tp----------yC----SYPPGTEYKVALAEAELLGACMMI-ISESMLEMTKALYKLKKAYSTLYEIQQMKKNPNytpy 170 Yarrowia lipolytica Q6CSC1 117 Nik--------tsS----LYPPGTEYAVTYTESCLLHALLML-FSESMVEGAKALFKLRKAYHMLQDILKEINASEkrkr 183 Kluyveromyces lactis ... Q0VF76 143 tlsrlm-srqgikS----IKEEELHAEVCYAECLVLKSAITFiQDDSLLSFLKSGVNVGSSYQIYKDCQQVLE------- 210 house mouse Q28DB0 114 EslsnlvskqsgdQ----LTEEEMHAEICYAECLLQKATLTFvQDENMINFIKGGMKIRTSYQIYKECHQLYSLAV---- 185 tropical clawed frog
A7TST2 182 nmsiyksetnhseasvdssnasfssvdipyeltreesnnslyqesaekvqkmrvrrltgshigntpaidrlrselgldgp 261 Vanderwaltozyma polys... Q8VE09 182 kkl----------------------------------------------------------------------------- 184 house mouse Q16TQ6 164 sp------------------------------------------------------------------------------ 165 yellow fever mosquito O94699 154 hst----------------------------------------------------------------------------- 156 Schizosaccharomyces p... A1CQ80 171 matpiesaapgsiplsmkrqgssnlqsssssissakikkaa-------ssattlaapventdlserltglnlssetlapg 243 Aspergillus clavatus ... A2QQE8 175 nsgnststeslprgagqgagsksvpas------------------------------------pvepidlkkelsdlsis 218 Aspergillus niger CBS... Q6CG79 171 sytpaelteyaka------------------------------------------------------------------- 183 Yarrowia lipolytica Q6CSC1 184 ssiylqeinestasfissgtcftsydipykltpeeeqdkelldl-ankvyslrrkrlcgahignspainrlrddvgaasl 262 Kluyveromyces lactis ... Q0VF76 -------------------------------------------------------------------------------- house mouse Q28DB0 -------------------------------------------------------------------------------- tropical clawed frog
A7TST2 262 kvtteensneysALS--ENmdf---sqaTIDEFIHSGVNLCYGILQVVLSLLPSGIGAVLSVVGFHGSREDGLRLVWR-A 335 Vanderwaltozyma polys... Q8VE09 185 ------teeplaSDAanDNhvvaegvteESLSRLKGAVSFGYGLFHLCISMVPPNLLKIINLLGFPGDRLQGLSSLTY-A 257 house mouse Q16TQ6 166 ------ppepanHDVggTTteditqikpEDVRRLMGAVSFGYGVFQLSISLLPPSLLKLISFLGFEGDRSMGVACLMH-S 238 yellow fever mosquito O94699 157 ----------------------grsdvdLANEYVQTGTLLCTGLFTLLISLLPPKMITILNVFGYKGDRDWALQCMWMpA 214 Schizosaccharomyces p... A1CQ80 244 dvkeastlgpadmLNhdPDsdi---fhnQIDIFVHSGSNFCFGILLLLISMVPPAFSKLLSIIGFHGDKERGLRMLWQ-A 319 Aspergillus clavatus ... A2QQE8 219 adseasasgpsdmLShdPDsdi---fknQIDVFVHSGANFCFGILLLLISMVPPAFSKLLGIIGFHGDKERGLRMLWQ-A 294 Aspergillus niger CBS... Q6CG79 184 ------------rharlgpkvsannvgesYDELIDTGFRLCFGIIQVVFSMIPPGLSKLLSAIGFKCSREDGLRLLWE-S 250 Yarrowia lipolytica Q6CSC1 263 kkgsdeetqefqLLS--DNani---nqaTMDEFIHSGVNLCFGILQVVLSLIPPAIGAVLSVVGFHGSREEGLRLVWK-S 336 Kluyveromyces lactis ... Q0VF76 211 ------------LMPenQS---------KTHRHLIGGIKFGVGVFNLMFSLVPPKSLKLLNMVGYSGDREVGLALLHD-S 268 house mouse Q28DB0 186 ------------TQGktCS---------DTHHQFEGGVKLGIGAFNLMLSLLPSRVLRLLEFIGFSGNREFGLSQLRE-G 243 tropical clawed frog
A7TST2 336 TK-QRNIHGCIGLLGLMFYYDGPFQFTDAdfdipvpenelkktkssstyeegdldgptLLHPGKILEDALLQSRALFPHS 414 Vanderwaltozyma polys... Q8VE09 258 SE-SKDMKAPLATLALLWYHTVVRPFFALdg-------------------------sdNKGGLDEAKAILLRKESAYPNS 311 house mouse Q16TQ6 239 RS-SVDMRAPLSTLALLWYYTIVTPFFALdg-------------------------snLKFEICSAQELIEESTE-FSKS 291 yellow fever mosquito O94699 215 LQrPTSFFAAVAFAALIQYYSGAVQLCSIykktp---------------------eepdGWPDKRCFEILEKVEKAHPDG 273 Schizosaccharomyces p... A1CQ80 320 SK-FHNLIGAIAAFSVLGYYNGFVRYCDImpdsip-----------------gqdedvQGYPQERLELLLAKMRKQFPKS 381 Aspergillus clavatus ... A2QQE8 295 SK-FHNLIGALAAFSILGYSNGFVRYCDImpdpv-------------------pgddvQGYPQERLEALLALMRKRFPKS 354 Aspergillus niger CBS... Q6CG79 251 IS-APNVQATVALVVLMRYYDSPMQSSDLilpgteeeliak---------gsffekksedsPRSRMYQQLMVARARYPRS 320 Yarrowia lipolytica Q6CSC1 337 TK-DRNIHGGIGLLGLLFYYDGPFQFTDIdfdipaarddn--------lpvtemdrptLLHPGKILTSALLQARALFPNS 407 Kluyveromyces lactis ... Q0VF76 269 AS-EPHINNILSVFTLLFYYNYVRVVVGV-----------------------------EKASTAATESLFLIYLEKFPNC 318 house mouse Q28DB0 244 AS-GNSIRAILCVLTLLFYHTYISTILGT-----------------------------GEANLEEAEALLEPYLKKFPNG 293 tropical clawed frog
A7TST2 415 ALWLLNEATMLSGQGRLRDSVKLMDSIe-ADKIEMRQVKSLLIFNRALTLVHLHEYERAADDFLSLLDISSWSHSLYHYF 493 Vanderwaltozyma polys... Q8VE09 312 SLFMFFKGRIQRLECQINSALTSFHTAl-ELAVDQREIQHVCLYEIGWCSMIELNFKDAFDSFERLKNESRWSQCYYAYL 390 house mouse Q16TQ6 292 SLFLFFRGRVERLKSNIKEAIQAYEFAy--rSSAQREIKLLCLHEIGWCRLIQLDYGTAMNNFKDLRRCSQFSKSFYAYL 369 yellow fever mosquito O94699 274 PMWPLHRAKLLSMVKKQDEAIVVLEELmaKPPPRLKQLEVLIVFEHALDCAFSHRYVDGANSFLKLSSLNDSSTALYSYF 353 Schizosaccharomyces p... A1CQ80 382 QLWVLEESRMCGANKNLDRALELLCg---GESSPLKQVEALRLFERSLNAMYLHKYELCAASFLECFELNTWSRSLYYYI 458 Aspergillus clavatus ... A2QQE8 355 QLWLLEESRMNGANKKLDVALELLCg---EDRSPLKQVEALRVFERSLNAMYLHRYELCAESFLECVELNSWSRSLYYYI 431 Aspergillus niger CBS... Q6CG79 321 SILVLQQGQAEATLHRLDEAIAILSVd--LNTVHMRQLKEPIYENRTKWLTCLHQYRTSANSFVELVDLTPKCHAWYNYL 398 Yarrowia lipolytica Q6CSC1 408 ALWLLQEARMLSKQGRLKEAVDLLDSId-HNTIEMKQVKALIVFEKATTLVYMHEFERGAETMLIMLSISEWSHALYTYF 486 Kluyveromyces lactis ... Q0VF76 319 VVLKFFRARFNMLNGNFESAKLKLQECi-ITQNEWKQVHHLCYWELMWCHIFLQNWKQAYNYASLLFQHSRWSKAIYIYS 397 house mouse Q28DB0 294 SIILFYAARIDILKGRFEQAQETFQKCi-VSQQEWKQIHHLCYWELMWCHSFQQDWLQAYRYADLLCKESKWSKATYVFQ 372 tropical clawed frog
A7TST2 494 AGSCYLEIYRMhqlg----vrksDRPEHFkQRATDLIFGAPNLLTRKSFnaRPLPLDRFMLRKVDQFKATqkrlkl-sdp 568 Vanderwaltozyma polys... Q8VE09 391 TAVCQGATGDV-------------------DGAQLVFKEVQKLFKR-----KNNQIEQFSVKKAERFRKQtp-------- 438 house mouse Q16TQ6 370 TVICQGAHGYF-------------------DELTKWRSEISELLSRSSQ--KESQIEKYIYRRCQKLPKsetet---ekf 425 yellow fever mosquito O94699 354 AAACFLQDVHV------------NANVEAlEKASKLLEPLHDLVAN-----KTAPLDVHIRRKVGKLIKRrasagnqggl 416 Schizosaccharomyces p... A1CQ80 459 TGSCHLSLYRNald------kdpAKAAEHaELAEKYFRLAPPLAGKKRFmaRQLPFDVFVARKVAKWEARakdwk--vpl 530 Aspergillus clavatus ... A2QQE8 432 AGSAHLSLYRNiag------tdaTAAAKHaEKAVEYFRKAPPLAGKKKFmaRQLPFDVFVSRKIAKWEARakewk--vpl 503 Aspergillus niger CBS... Q6CG79 399 AACCLLEVYKE------------EEDPAAkAQAGVLLEKAATHASD-----KKQHLRKYVAHRIQQLKKEgpl------v 455 Yarrowia lipolytica Q6CSC1 487 AGCCYLEMFRKyemgilngenaaEKKAYYkERATNLVFESANMVGKKKFmsKILPLDRFLLRKVDQFKKFqniiks-sdp 565 Kluyveromyces lactis ... Q0VF76 398 KAIILALIPPD------------CVDSEN-ESLSSYFLRVDSLRIKILG--SSVPIEKFIAEKSQRYGTTt--------- 453 house mouse Q28DB0 373 KAAILSMLPDD------------VVKTTG-EDIVALFRQVEGLKQRIAG--KSIPTEKFAVRKSRRYASDn--------- 428 tropical clawed frog
A7TST2 569 ldAIATSPVHELQYFYNGYNRMGKQDLE-LANIML-----------TEyhnpaidaKepNQEM-----IKDFLVSLTYRR 631 Vanderwaltozyma polys... Q8VE09 439 trALCVLASIEVLYLWKALPNCSFPNLQrMSQACHe----------------------vDDSSvv--gLKHLLLGAIHKC 494 house mouse Q16TQ6 426 dcGYWRLLVYEMLFMWNALSSCSEETLSeVIEDCCks---------------------qDESTepsqgLRQLILGASLGC 484 yellow fever mosquito O94699 417 aeYVGFSPLYELVYVWNGFRRMTDDELSkFDVERMepw------------------qdqDDDI-----CQALIKATVLRN 473 Schizosaccharomyces p... A1CQ80 531 vdAVGVDPIEEMIFFWNGHSRMTDEHLL-ESLQKLawce---ssanKTws-----rEgpEEKA-----ILKLLRAAVFRS 596 Aspergillus clavatus ... A2QQE8 504 vdAVGVDPIEEMIFFWNGHSRMTQEQLE-ESMTKLawse---seanKTws-----rEgpEEKA-----ILQLLRAAVLRA 569 Aspergillus niger CBS... Q6CG79 456 dvAVKKPLLGEVFYYWNGYSKMPQNALE-KSYKKLng--------------------mnDPQS-------ALLQAVILRN 507 Yarrowia lipolytica Q6CSC1 566 ldSIGVSPVHELIYFYNGYNRMTMKELN-LSLKSL-----------TEyrnptidlQnpDQEL-----IKDLLTSLVLRR 628 Kluyveromyces lactis ... Q0VF76 454 -gWFTAQPLLEFIYAWSGFRVMSKKIELiSSWLLIidkgkellsenPNee----ygI--DDMS-----LLNLLKGLCLKH 521 house mouse Q28DB0 429 -pVKLTLPALEMVYVWNGFTIVGKRPDLtENVLVTiekaevalqseKNpse---yhP--DDLC-----LVQLLKGVCLKH 497 tropical clawed frog
A7TST2 632 L 632 Vanderwaltozyma polyspora DSM 70294 Q8VE09 495 L 495 house mouse Q16TQ6 485 G 485 yellow fever mosquito O94699 474 L 474 Schizosaccharomyces pombe 972h- A1CQ80 597 L 597 Aspergillus clavatus NRRL 1 A2QQE8 570 M 570 Aspergillus niger CBS 513.88 Q6CG79 508 L 508 Yarrowia lipolytica Q6CSC1 629 T 629 Kluyveromyces lactis NRRL Y-1140 Q0VF76 522 L 522 house mouse Q28DB0 498 L 498 tropical clawed frog
Jiyao W et al.(2023). "The conserved domain database in 2023.",