6ZCE


Conserved Protein Domain Family
eIF3_subunit

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pfam08597: eIF3_subunit 
Translation initiation factor eIF3 subunit
This is a family of proteins which are subunits of the eukaryotic translation initiation factor 3 (eIF3). In yeast it is called Hcr1. The Saccharomyces cerevisiae protein Swiss:Q05775 has been shown to be required for processing of 20S pre-rRNA and binds to 18S rRNA and eIF3 subunits Rpg1p and Prt1p.
Statistics
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PSSM-Id: 462530
Aligned: 153 rows
Threshold Bit Score: 72.3268
Created: 23-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6ZCE_t         1 MS-WDDEAIngsm---gndDAVLMD-------SWDAEIgDDE-PVMQSWDAEE------EEKKPAPKPKKEQ---PK--- 56   Saccharomyces ...
XP_002870534   1 MDdWEAEDFqplp---akvELKS---------NWDDEDvDEN-DIKDSWE-EEdvs-apPPVV---KPASENapkKAavk 62  
Q9C8D8         1 MDdWEDEKIaplp---akvELKS---------NWDDEDvDEN-EIKDSWEDDDdep-aqPPVI---NPAPEKapkKAapk 63   thale cress
KRH09433       1 MDdWEDEHIapidl-tlkdPVKS---------NWDDEDvDEN-DVKESWE-DEdep-apAPAA-PAVKTTEKapkKSsdk 66  
XP_009407499   1 MAdWEEEDFepappslitnKPKS---------QWDDEDvEDE-DVKESWE-DEevp-vqAPKA---EETVQTtasKTgrk 65  
BAJ99710       1 MEdWDADDFqpiapvvkaqPLKS---------NWEDEDaDED-DVKESWEEEEek--pkPPPV-------EKpapKPsak 61  
XP_004952075   1 MEdWDAEDFqpaapvviaePLKN---------QWADEDvEED-DVKDSWEEEDeek-pkPPPV-------EKaaaKPssk 62  
XP_015626133   1 MEdWDSEDFqpavpsakaePLKS---------KWADEDvEED-DVKESWEEEEeek-pkPPPV-------EKtapKPsgk 62  
XP_004360218   1 MGdWDSEDYtpv-----------------agnRWEEEN-RDQgDGMDDWDAEPeek-eeVEEPTKVPSKPApkp------ 55  
EFC38553     749 nlsWEDAEId--------dKPFSSTqttagddDWED---FDL----DAVEKKQqeelkkKQEQ-------------Laea 800 
6ZCE_t        57 ---KVKKGKESSADR----------ALLDIDTLDEKTRKELIKKAEMESDLNNAADLFAGLGvaeehpraralqkeqeeq 123  Saccharomyces ...
XP_002870534  63 aveKKVKTVEAPKGS------------SREEPLDPIAEKLRMQRLVEEADYQATAELFG--------------------- 109 
Q9C8D8        64 tveKKGKAVEVPKEA------------PKEKPLDPIAEKLRQQRLVEEADYRATAELFG--------------------- 110  thale cress
KRH09433      67 ateKKGKTVEPIKEE----------------PLDPVAEKLRQQRLIEEADYKATKELFSGG------------------- 111 
XP_009407499  66 pagKKEKLPEAKTSE-----------ISNEVLADPVAEKLRQQRLVEEADYKSTAELFA--------------------- 113 
BAJ99710      62 aavKKGKQPSTSTEV-----------VEDDVLDDPISEKLRQQRLVEEADFKATAELFAK-------------------- 110 
XP_004952075  63 apaKKGKQQASTSAE-----------EPDEPPLSPTSEKIRQQRLVEEADFKSTTELFAK-------------------- 111 
XP_015626133  63 gaaKKGKQQASTSSE----------VVQDEALDDPALEKLRQQRLVEEADFKSTTELFGK-------------------- 112 
XP_004360218  56 lskAQALKKALELREk--------eDKVSTDDFDIYKDKMKQREMQEEADLQNANDVFQGIS------------------ 109 
EFC38553     801 erqEKLKKQQQKEQKsnkkaetrttSSGNAPTGDKKVEGMYLDYMEKKTSYDEAEALIGGA------------------- 861 
6ZCE_t       124 alkrPAFtKDTPIETHPLFNAETKREYQDLRKALTAAITPMNKKSplNYsSSLAIDLIRDVAKPMSIESIRQTVATLNVL 203  Saccharomyces ...
XP_002870534 110 --------VKTEEKSVDMLIPKSESDFLDYAELISQRLVPFEKSF--HY-IGLLKAVMRLSVANMKAADVKDVASSITAI 178 
Q9C8D8       111 --------VKDDDKNLDMFIPKSESDFLEYAEMISHRIKPYEKSY--HY-IALLKTIMRLSLTNMKAADVKDVASSITTI 179  thale cress
KRH09433     112 --------KEKDEKNLDTFIPKSESDFLEYAELISHKLRAFEKSY--HY-IGLLKAVMRLSTISLKGADAKDIASSVTAI 180 
XP_009407499 114 --------KKGDEKTLDNFIPKSENDFLEYAELLSHKILPYEKSF--HY-IGLLKAVMRLSMTSLKAADAKEVASSVTAI 182 
BAJ99710     111 --------KDGSEKSLETFIPKSESDFAEYAELIANKIRPYEKSF--HY-MGLLKNVMRLSMTSLKGADAKEISSSVTAI 179 
XP_004952075 112 --------KGGDQKSLDTFIPKSESDFAEYAELIANKLRPYEKSF--HY-MGLLKNVMRLSMTSLKGADAKDISSSVTAI 180 
XP_015626133 113 --------KDGSEKSLDTFIPKSESDFAEYAELIANKLRPYEKSF--HY-MGLLKNVMRLSMASLKGADAKDISSSIAAI 181 
XP_004360218 110 ----VREtTPTAQCSLDTMNPTSEKDYENYSNALSKYVTKFEKSY--HY-PTIIKTILKNATANMTSQETNDLVKSLTVI 182 
EFC38553     862 -----G--SEFAKPKIDLLSPKTEKEFNEFGVLVADKLLEFEDSK--FY-LDLVKRIVEEATINWDSAQLRELTKHVTNV 931 
6ZCE_t       204 IKDKEREERQArlarvrggtatgGAGKKKVK-G-KTNL--GGAFk--kDQdFdldg----addFefgddDFM 265  Saccharomyces cerevisi...
XP_002870534 179 ANEKLKAEKEA------------AAGKKK-SgKkKQLhvdkpd---ddlvgGp---------yDamdddDFM 225 
Q9C8D8       180 ANEKLKAEKEA------------AAGKKK-GgKkKQLivdkan---ddlvaGp---------yDamddfDFM 226  thale cress
KRH09433     181 ANEKIKAEKEA------------NAGKKKIGgKkKQLnvdkpd--edfvpaDr---------yDalddyDFM 229 
XP_009407499 183 ANEKLKAEKEA------------NAGKKKQGtKkKQLhvdkae--ddyvtaGg---------yDdvddyDFM 231 
BAJ99710     180 ANEKIKAEKEA------------AAGKKKGGaKkKQLhiekgeedfvarpgAs---------fDdpdefDFM 230 
XP_004952075 181 ANEKIKAEKEA------------AAGKKKQGaKkKQLhiekgdddfipgrgGg---------yDdpdeyDFM 231 
XP_015626133 182 ANEKIKAEKEA------------AAGKKKQGaKkKQLhienkdd-dfipgkGn---------fDdpdeyDFM 231 
XP_004360218 183 VNDKIKQEKNAv----------gKGKKPTKAaAtKKTLqlDNEM-------------------EnfgeeDFm 225 
EFC38553     932 SNKRMEEEKERk-----------AGGKKKKKtVnIERDlsASADp--fSDlGdgtggrtkyddD-----DFM 985 
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