5XPD


Conserved Protein Domain Family
MtN3_slv

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pfam03083: MtN3_slv 
Sugar efflux transporter for intercellular exchange
This family includes proteins such as drosophila saliva, MtN3 involved in root nodule development and a protein involved in activation and expression of recombination activation genes (RAGs). Although the molecular function of these proteins is unknown, they are almost certainly transmembrane proteins. This family contains a region of two transmembrane helices that is found in two copies in most members of the family. This family also contains specific sugar efflux transporters that are essential for the maintenance of animal blood glucose levels, plant nectar production, and plant seed and pollen development. In many organizims it meditaes gluose transport; in Arabidopsis it is necessary for pollen viability; and two of the rice homologs are specifically exploited by bacterial pathogens for virulence by means of direct binding of a bacterial effector to the SWEET promoter.
Statistics
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PSSM-Id: 397278
Aligned: 21 rows
Threshold Bit Score: 77.6214
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5XPD_A 132 KVLGGICVGFSVSMFAAPLSImRVVVRTRSVEFMPFSLSLFLTINAVTWLFYGLAIKDF--YVALPNVLGAFLGAVQMIL 209
Q9BRV3 127 QQLGLFCSVFTISMYLSPLADlAKVIQTKSTQCLSYPLTIATLLTSASWCLYGFRLRDP--YIMVSNFPGIVTSFIRFWL 204 human
Q84WN3   6 FYIGVIGNVISVLVFLSPVETfWKIVKRRSTEEYKSLPYICTLLGSSLWTYYGIVTPGEy-LVSTVNGFGALVETIYVSL 84  thale cress
Q9ZV02  10 FLFGLLGNIVSFGVFLSPVPTfYGIYKKKSSKGFQSIPYICALASATLLLYYGIMKTHAy-LIISINTFGCFIEISYLFL 88  thale cress
O82587  12 FVFGLLGNLISFAVFLSPVPTfYRICKKKTTEGFQSIPYVVALFSAMLWLYYATQKKDVf-LLVTINSFGCFIETIYISI 90  thale cress
Q9CXK4   9 SFLSSACVLFTLGMFSTGLSDlRHMQRTRSVDNIQFLPFLTTDVNNLSWLSYGVLKGDG--TLIIVNSVGAVLQTLYILA 86  house mouse
Q9XX26  11 PYLSFTALSSTVAFFLCGLQIcHRIKTRGSSEGTSPAPFLLSFLSCGLFIQYGLLKDDD--VITYCNGIGCFLQACYLMY 88  Caenorhabditis elegans
Q17757  13 NLLSILAFFTTVGLFFCGIPIcRQIWKRKDTKEISGAPFLMGVVGGCCWMTYGWLKNDG--TVKWVTGCQVILYTTYTIF 90  Caenorhabditis elegans
Q7JVE7   8 SLLSTTAVISTVFQFLSGAMIcRKYIQKKSTGDSSGVPFICGFLSCSFWLRYGVLTNEQ--SIVLVNIIGSTLFLVYTLI 85  fruit fly
Q9SW25  10 VTFGVLGNIISFIVFLAPVPTfVRICKKKSIEGFESLPYVSALFSAMLWIYYALQKDGAgfLLITINAVGCFIETIYIIL 89  thale cress
5XPD_A 210 YIIFKYYKT 218
Q9BRV3 205 FWKYPQEQD 213 human
Q84WN3  85 FLFYAPRHL 93  thale cress
Q9ZV02  89 YILYAPREA 97  thale cress
O82587  91 FVAFASKKA 99  thale cress
Q9CXK4  87 YLHYSPQKH 95  house mouse
Q9XX26  89 FYYMTRNRR 97  Caenorhabditis elegans
Q17757  91 YWCMTKKKL 99  Caenorhabditis elegans
Q7JVE7  86 YYVFTVNKR 94  fruit fly
Q9SW25  90 FITYANKKA 98  thale cress
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