2YVX


Conserved Protein Domain Family
MgtE

?
pfam01769: MgtE (this model, PSSM-Id:396364 is obsolete and has been replaced by 460317)
Click on image for an interactive view with Cn3D
Divalent cation transporter
This region is the integral membrane part of the eubacterial MgtE family of magnesium transporters. Related regions are found also in archaebacterial and eukaryotic proteins. All the archaebacterial and eukaryotic examples have two copies of the region. This suggests that the eubacterial examples may act as dimers. Members of this family probably transport Mg2+ or other divalent cations into the cell. The alignment contains two highly conserved aspartates that may be involved in cation binding (Bateman A unpubl.)
Statistics
?
PSSM-Id: 396364
Aligned: 934 rows
Threshold Bit Score: 35.8727
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
2YVX_D         343 VPVLLGTGGNTGNQSATLIIRALATR------DLdlrdwrrvflkeMGV-GLLLGLT-------LSFLLVGKVYWDGH-- 406 Thermus therm...
Q8TWZ9          46 LPALMDFRGNVALAHSARTATATHLG------DEera------lqsSLA-VLLIGLM-------VPPVIGSVVY-YAYg- 103 Methanopyrus ...
jgi:Kcr_0881   256 YPAIIDTLGDCGAIFGSTSTTKLFTGlmepslSEissr-----ineLAQ-IWIAGLIyyflyaiIGFSVGGS-------- 321 Candidatus Ko...
O28767         205 YPAVIGSIGNYGSIMVARTSTKLHLG------Elsvg-----klsdAPY-VFLTSVV-------IAPTIYVLASLFAStf 265 Archaeoglobus...
jgi:Ferp_2521  251 YPAIIGSLGNFGGVVGARVSTKLHIG------EVerffek-dvlldILA-LTTLTLP-------LASIMYSSGVLVAYfi 315 Ferroglobus p...
WP_015589870   259 YPAILDSSGNYGSIIGAKTSTMLHLG------EIgkpldr-kivyeILI-YSMTGIP-------LAVIMNSLATLIVKvt 323 Archaeoglobus...
Q8U1P8         256 YPAILDTTGNLGSIIGAKTSTKIHLG------EIektlnk-diafeIGV-YTILAYP-------LALLSNGIAVLVGRfl 320 Pyrococcus fu...
Q5JH39         263 YPAVLATTGNLGAIIGTKTSTRIHLG------ELegflnr-kilveILV-YSAVGAL-------LGLLANIIAILVVKvt 327 Thermococcus ...
jgi:Arcpr_1246 250 YPAVLDSLGNYGCVIGSKTSTRLHLG------EIdklfdi-rsasdIVS-LLSTSIP-------LSVIMYSLGYMISIn- 313 Archaeoglobus...
jgi:Igni_0614   42 MPGLAEDRGAVYGSLAAKYSTMLYLG------EAsnake--llkskVTYsAIVVGVI-------GGLYVILL-------- 98  Ignicoccus ho...
2YVX_D         407 ----PLLLP-VVGVSLVlivfFANLV---GAMLPF------LLRRLGVDPALVSNPLVATLSDVTGLLIYL 463 Thermus thermophilus HB8
Q8TWZ9         104 ----GDLST-LVGTAFLtvlsVTAVV------TPVtvgivrMAAMLGFDPDHVAPPLTTALSDVLTVAFLF 163 Methanopyrus kandleri
jgi:Kcr_0881   322 ------LRS--FAIPLLvysiLFPLIslfTFSLAI------VAFRKGLNPDNFIIPLETTMTDTITTVMLs 378 Candidatus Korarchaeum...
O28767         266 tgapFPEAK-DFLYFMIvylaLAAFVllfSTTLSI------WLHRVGVDPDNGGIPLTTTLTDIVGTTAVV 329 Archaeoglobus fulgidus
jgi:Ferp_2521  316 ---fGRVPG-IYYFFFPfymlTALFVmilGNLISV------TFHKFGFDPDNVTVPAITTLADLIGTALTI 376 Ferroglobus placidus D...
WP_015589870   324 ---lGKTVG-LVPIFLLlypiFLLFVmtiAHLIAI------VSEKVGFDPDNTTVPVITTIADMIGTAFTV 384 Archaeoglobus sulfatic...
Q8U1P8         321 ---lNKTMG-IIPEFVLlypiLAHLVmwfAYFIAI------FAEKMRLDPDNVTVPTITTLADVFSTLFVV 381 Pyrococcus furiosus
Q5JH39         328 ---lGARVG-LVKPFLVlypiLIFGVmwmAYFMAI------IFDRTGLDPDNATVPTITTIADIISTLFIV 388 Thermococcus kodakaren...
jgi:Arcpr_1246 314 ---lGKSVN-INYAFFLlypiVVLVVmflGYLLAF------VSYRFGLDPDNVTVPTITTLADLIGTTFTV 374 Archaeoglobus profundu...
jgi:Igni_0614   99 ------VSTvAEPLAPLiyflVSRGLi-lLTLVPLtaylcyAAFLKGLDIDLTVVSLITVIADLLSAISLF 162 Ignicoccus hospitalis ...
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap