Conserved Protein Domain Family
Inovirus_Gp2

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pfam11726: Inovirus_Gp2 
Inovirus Gp2
Isoform G2P plays an essential role in viral DNA replication; it binds to the origin of replication and cleaves the dsDNA replicative form I (RFI) and becomes covalently bound to it via phosphotyrosine bond, generating the dsDNA replicative form II (RFII).
Statistics
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PSSM-Id: 432027
Aligned: 14 rows
Threshold Bit Score: 126.734
Created: 24-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
P52125          17 RIKQVIDDSLNEHLNSMILRVDLHDPIDTEn--mDNpffqprvdsGAISRFTSALKAKL------------KHDKHIKTQ 82  Escherichia c...
WP_024913214    18 TILEVLSYSTNEYPSIMAVRTDYHYPPILE----DTvgcfhnlkpGAISRSINALKEML------------KNSELRRKR 81  Chania multit...
P77657          18 KINKLLCYLTNRYPRLIAVRVDLHYPKIVDn--gDNiccfpnlepGVISRMRESLRAKL------------EADRTRKVR 83  Escherichia c...
Q8EGZ4          26 NIRSVMDCVVQNYSKVFAVRVDLRFPDMFEs--gDT---------AVITRFFESLKAQL------------KADYQAKLR 82  Shewanella on...
Q5E061          38 KIYNTIDKAITEYPRTMVVRVDLRMSKSLLf--dNS---------SVIKNFIASLDSQI------------QADLNRKKR 94  Aliivibrio fi...
jgi:Tola_2275   33 RIIETVQKSLRYYSRVRAFRIDLRFANDYMdgdvDTpshfqqadpKAITRFFESLKSQL--------------KVYRKNK 98 
WP_025421278    34 kslavVYNTLEHDNRIFACRTDLRFAEDHVsddpDSlvchqrvdpQAITRCIESLKSQL------------REDHRRSGR 101 Sodalis praec...
jgi:Alvin_3272 175 gslNYINYLFERYARLLVVRVDLSF------------------------LTPSQCHDRDwtpvtfedalayRERFTRSWK 230
Q9KUM0          40 EIDRVLTEALNQYPRIFAVHINLNLPSDFGed-----------ylTVFAHFFRILESAT-------------NELCKDKY 95  Vibrio cholerae
Q9KUL9          35 TMDKVFDQALTQYQRTLAMRLDLYLPKDHQd--tDL---------SILNDYFDILKEKI------------DAD------ 85  Vibrio cholerae
P52125          83 RkdWPDSRHSTLRYAWVREYTKNRKRHYHLILCFNQDAYYHLGDYDl-NRNTLRTMITTAWYSALGIPIDSSG-KLVNYP 160 Escherichia c...
WP_024913214    82 N--GARVHPNTLRNVWAKEFSQSGKCHFHVCFVFNEQAYNKLGDYN--IDTSLRMMITRAWYSALGLELEDYP-GLVHFP 156 Chania multit...
P77657          84 E--DKRIYRCPLFIIWAKEYSESGKCHYHICLLFNKDAYYHLGDYD--QDDNLRGMITGAWYSALRLERDDHP-GLVHFP 158 Escherichia c...
Q8EGZ4          83 NttDGLVHASELFYIWVKEISGRDKCHYHVCLFFNGHAYKSLGKFEl-DRANMYNRIHKAWASALRLDISHVQ-GLIHFP 160 Shewanella on...
Q5E061          95 K--GIRVRACKIRYVWVKERSTSLSNHYHLVLFFNKDVYHCLGDFK--NEDNLSHKIKKAWCSALDLDINEGS-RLVNFP 169 Aliivibrio fi...
jgi:Tola_2275   99 N---IMVSRDDFKYIWTREKDESFHHHYHLVLLFDKDVYYHLGDCSpdNSSGIAAMIQKAWCSALRVSFPEYA-TLVHFP 174
WP_025421278   102 H-----GKPALPAYVWARERDTSEHPHYHLMLLFKRNVYGYLGNYTnrDADNMATRMQKAWCSAVGLNYPYYA-ALANFP 175 Sodalis praec...
jgi:Alvin_3272 231 R---EPLFEHLVGYVWKIEHGALKGFHTHWLFFFDGSKVr--------EDMTLGHLIGEHWKVIV--------------- 284
Q9KUM0          96 TdrTYRYQQTVIRYIWAKESK-STSKHHHLILLFDRDLFQNLGTGRegWGRFLYKKVRKTWDRVVEAYYRQPCsGLAYSP 174 Vibrio cholerae
Q9KUL9          86 ----------SLPYVWRKRADKTPSHNYRVMLFLDDSQYFGPAICWd-KGNQLVDHLKTAWKEAIEKHYKGKErSIILFN 154 Vibrio cholerae
P52125         161 PNGKYLLN-RKRDNFEQTY----------------SDLMNRVDYMTK---VRTKIVGDGDRNFGCS 206 Escherichia coli K-12
WP_024913214   157 DNCRYILD-RNSADYIYEY----------------GELLHRLDYLTK---LDSKIYEEGERNFGGS 202 Chania multitudinisentens
P77657         159 ENCKYVLD-TNSTDFQQNY----------------QALLTRLDYLTK---VESKVFGEGDRNFGCS 204 Escherichia coli K-12
Q8EGZ4         161 ENAQYLLC-RNQADFTYIY----------------QDLFKRLSYFAK---TDTKIYGNGNHNFGCS 206 Shewanella oneidensis
Q5E061         170 NNGVYWLD-KNSRNFDDDF----------------DSLFYRASYLAK---LETKKYGNGMRSFGCS 215 Aliivibrio fischeri ES114
jgi:Tola_2275  175 DNCAYNLEgKNATLQDEKF----------------IWALERFLYLSK---VDTKTTDDGFRNFGCS 221
WP_025421278   176 KNQSFKFDrSDALARSPVY----------------VDFLLRLSYLAK---ENTKDVHDGYRNFGTS 222 Sodalis praecaptivus
jgi:Alvin_3272 285 GSHATYWN-CNV--YKTQYrhlgigqidhadqtkrQALQRVVQYLCKvddFISLKHTGRRRAFGRg 347
Q9KUM0         175 TNEGFELF-SDTESFPLQL----------------NEFFYRISRLAKptaNRNAHP---NKSFGCS 220 Vibrio cholerae
Q9KUL9         155 NRGNDGLGtRCKSKDTNIK----------------RCVFHRLSSFAEawkEE-------RYCFGSS 197 Vibrio cholerae
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