2OKG,4L5J,4OQQ


Conserved Protein Domain Family
Sugar-bind
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pfam04198: Sugar-bind 
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Putative sugar-binding domain
This probable domain is found in bacterial transcriptional regulators such as DeoR and SorC. These proteins have an amino-terminal helix-turn-helix pfam00325 that binds to DNA. This domain is probably the ligand regulator binding region. SorC is regulated by sorbose and other members of this family are likely to be regulated by other sugar substrates.
Links
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Statistics
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PSSM-Id: 427778
Aligned: 22 rows
Threshold Bit Score: 237.904
Created: 22-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
2OKG_B                4 KDVLGLTLLEKTLKERLNLKDAIIV--SGDSDQs-PWVKKEXGRAAVACXKKRFSGKN--IVAVTGGTTIEAVAEXXTPd 78  Bacillus...
Q9RT33               86 DPQGHPCSLQARLMERWPGVQAQVVglPPHSTQ--DLRLERVALAAAHWLGSALRPGL--VVGLAWGNTLDAVSRALTP- 160 Deinococ...
WP_004144198         59 HPVANCLDYAQLLQEKYRLIECNVV--PAFSE---ESTLDSVSFGCYQLMARYLQDDKekIIGLGSGLTLKKALQRIDF- 132 Klebsiella
rhodo:RCAP_rcc02021  59 hKISACLDLEVALSRRFALKLARVV--PALPAG--VDTARGTAPAAAQLLERYLAQPEplIIAFGTGRSLSAMAAEVIR- 133
Q3J1R9               62 HRVSGCLHLEAALIRRFGLKLARVA--PSLGSE--VDPLPSIAPTAAAEVERVLRSERpmVVAFGTGRSLRATVEEMTS- 136 Rhodobac...
4OQQ_B                7 DPFEDLDALGSILEEKYGLLEAHVVfsPTPDy---AGITHDLSRYGAEYMHETVKDGD--IVGVSWGTTMYQIAQNMQP- 80  Bacillus...
Q9CGB1               54 SPIERSFELEKQFKTLFDIPQIYII--KDVEDGn----SESLIKFAAKRIESHILNSQ--TVGTVWGETIFRIIDHFTP- 124 Lactococ...
Q9L0Z6               89 VPAELDAERSDALRARYGLRHAVVV--ESPADAeeTPDPENLGEVAADLLGELVNEGD--VLGLAWGRSTIHMAAALDR- 163 Streptom...
Q9KER9               57 DENIHTVELEQRLEKKYHLKEAIVV--PTSGLTq-DMIKRAIGKATSYYVSKNIKGMD--SIGISWGTTVSSFVQEYPY- 130 Bacillus...
wugsc:KPN_04408      59 yDYNENLWLEQQLKQKFGLKEAVVA--SSDGLLe-EEQLSAMGQHGALLVDRLLEPGD--IIGFSWGRAVRSLVENLPQa 133

2OKG_B               79 SKNRELLFVPARGGLGE-DVK--NQANtICAHXAEKASGTYRLLFVPGQLSQGAY-SSIIEEPSVKEVLNTIKSASXLVH 154 Bacillus...
Q9RT33              161 RPLSGVQFVQLNGSASVlELSs-GFVGgTLTRLAQAVRGQAHLFPVPTFFDDPATkQAMWRERSVQHVVQLQRQAELLLF 239 Deinococ...
WP_004144198        133 DSLN-TRCVALISAMNA-DGQc-NYYDdVPLLLTRKIKAKYYQWPAPRYAQSADEyEMWCTNRLFRSVSGVAREADVIFV 209 Klebsiella
rhodo:RCAP_rcc02021 134 TPLAAHRIVSLISNIAP-DGS--ASFYdVILRMADKLQLPHYPMLVPVITDTIAErALFNALRPVQAVMELAARADVTFV 210
Q3J1R9              137 MVCEQHKIVSLNGNISA-DGS--ASYYdVIFRIADRVRAPHYPMPMPVIAQDAAErELFHALKPVQSVLRLARNADVTFV 213 Rhodobac...
4OQQ_B               81 KQVKGVEVVQLKGGISHs-rVn-TYSAeTIQLFAEAFQTMPRYLPLPVVFDNADVkRMVEKDRHIERIIEMGKQANIALF 158 Bacillus...
Q9CGB1              125 QEHSDLLFTQMMGENRKy-HSa-AGSMrMVEKAAKQFSAQYVTLSGPLYITNPAVrKGMTEEIASQPAFTTAKRMDLIFS 202 Lactococ...
Q9L0Z6              164 --LPPCTVVQLTGVYDAg-TAe-RGSVeAVRRAAQVSGGDAHPIYAPMLLPDAATaQALRHQTGIARAFEYFDKVTVACV 239 Streptom...
Q9KER9              131 EQHRELKVIPLVGGMGRk-FVe-LHSNlLAYELAKKMNCECSYLYAPAMVEAKELkERLIQSEDIASVLEEGRNVKMAVV 208 Bacillus...
wugsc:KPN_04408     134 SQSRQVICVPIIGGPSG-KLEsrYHVNtLTYGAAARLKAESHLADFPALLDNPLIrNGIMQSQHFKTISSYWDSLDVALV 212

2OKG_B              155 GIGEAKT--XAQ---RRNTPLEDLKKIDDNDAVTEAFGYYFNADGEVVH---KVHSVGXQLDDIDAIPDIIAVAGGSSKA 226 Bacillus...
Q9RT33              240 SVGSPHAalPSHvyaAGYLDPDDLTQLEREGAVGDIATMFFRADGSWDGlslNARSSGPDLALIRDHPNTACIVADPGKA 319 Deinococ...
WP_004144198        210 GIGPLGT--QSPifkDGFINQAQMDELTARGGIGEILGRFIDAQGDVVDseiNRMITSYDIRQS--HCPRIAAACGEHKR 285 Klebsiella
rhodo:RCAP_rcc02021 211 GIGQLND--EAPlfkDGFITRAQHAELQAAGAVGEIVGGIFDAEGRYIDtetTRLIGSFRIPAE-REQPVIGIAAGLSKQ 287
Q3J1R9              214 GLGQMGE--DAPllkDGFITPDELAEMQELGAVGEVAGWVFDSEGRYLEtsiNQRVAGVRVE-LSEDRTVVAIAGGRRKL 290 Rhodobac...
4OQQ_B              159 TVGTVRD--EALlfrLGYFNEEE-KALLKKQAVGDICSRFFDAKGNICSsaiNDRTIGVELQDLRLKERSILVAGGSRKV 235 Bacillus...
Q9CGB1              203 GLGTLASvnSIPiweQH--TNEIFPDINLGAIAGMAYGRPYDINGNILVtpeNDCVFGVDMKTIFQPPKRVGVVKSKFKT 280 Lactococ...
Q9L0Z6              240 SIGSWEP--GISt-vHDMLSDEERAHYASLGVAAEMSAHLFDAEGRRVGrdlGERCITVKADQLRRIPEVVAIAGGQRKA 316 Streptom...
Q9KER9              209 GIGSPFK--GSTmkvMNYLKEEDIATLKKIGAVGDMSSRFYDALGQPIDhplNELVIGIDLDELKRIPIVIGVSEGAHKV 286 Bacillus...
wugsc:KPN_04408     213 GIGSPAI--RDGanwHAFYGSEESDDLNARHVAGDICSRFYDINGGLVDtnmSEKTLSIEMAKLRQARYSIGIAMGEEKY 290

2OKG_B              227 EAIEAYFKKPRNTVLVTDEGAAKKLLR 253 Bacillus subtilis
Q9RT33              320 AALRAALDGGLLRTLIVDETTAAGVLG 346 Deinococcus radiodurans
WP_004144198        286 PAILAALKGGWINGLVTDEHTARWLLt 312 Klebsiella
rhodo:RCAP_rcc02021 288 AAIRAALRGRLINGLVTDESTARALLA 314
Q3J1R9              291 AALHAGLRGRLFNGLITDELTAQALLS 317 Rhodobacter sphaeroides 2.4.1
4OQQ_B              236 SSIHGALTGKYANVLIIDQHTARALVN 262 Bacillus subtilis subsp. subtilis str. 168
Q9CGB1              281 QATLGALRGKFFTELIISESIAERILA 307 Lactococcus lactis subsp. lactis
Q9L0Z6              317 AAIDAVLRSGLVTSLVTDTSAADYLMT 343 Streptomyces coelicolor
Q9KER9              287 DSVEAALKGGYLDVLVTDDSTAQSLIN 313 Bacillus halodurans
wugsc:KPN_04408     291 SGILGALHGRYINCLVTNRETAELLLK 317
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