586352 50 SSKYDPDNPNKDKLGTYDGVFVPTALNVLSilmflrfgfiLGQLGIICTIGLLLlsyTINLLTtLSISAISTNGTvrgGG 129 baker's yeast 11135712 -------------------------------------------------------------------------------- Mycoplasma pneumo... 12643674 1 ------MKQQKPKISFIA-AMLIVIGSSIG----------AGIFFKSSTVLENSqasLVLAIFnWLVASVAVIAM---AL 60 Mycoplasma pneumo... 15899059 2 ERKQVFVRETSGLIKHVSLTDAVMLNIANMsi-------gIALFQSISPYITRG----GVLWI-ASLIGLFLALP---QA 66 Sulfolobus solfat... 15899282 6 IMTKLFVRETSGLTKNVSLLDVTMLNVANMga-------gLAIFIGISPYIVEG----AVLWI-ASLLTFLFTLP---LV 70 Sulfolobus solfat... 15899442 7 SVFIRQSSGLVREVSPWASFFATFGLVTGG----------IPILIVSWLYLAP-----GANWTlSYLISLLPTLG---MA 68 Sulfolobus solfat... 15899444 5 SKKGAFLRESSGLVREFGILDALWFNIALLgl-------lFSTYYVASTGPLVG---GNPLLG--LLLPIVGFFLv--GI 70 Sulfolobus solfat... 15899894 3 NKNRIFVRETSGLIKNVSLWDAVALNIGNMsa-------gVALFESISPYVQQG----GVLWL-ASLIGFIFAIP---QL 67 Sulfolobus solfat... 13541618 57 FKKPMLKETRNPVYGFFT-LFAIGLGTTIG----------SPLFVLIPENIYEY---FYVTII-SLCLAIVMSYLl--AY 119 Thermoplasma volc... 16081619 73 FRKPTLKETGSPVYGFFT-LFAIGLGTTIG----------SPLFILIPENVYEY---FIVSIA-SLILAIVMSYLl--AY 135 Thermoplasma acid...
586352 130 AYYMISRsLGPEFGgsiGLVFFLGQVFNAGMNavgiiepllynlgysaqgeppaalgellprghwheftyatvilflcfs 209 baker's yeast 11135712 -------------------------------------------------------------------------------- Mycoplasma pneumo... 12643674 61 ALIEIASvRNDNLS----IISWVKVFNRRWLYhg---------------------------------------------- 90 Mycoplasma pneumo... 15899059 67 LVYTIFNrKIGRTG---GDYVWISRNLDGAIGtifavay----------------------------------------- 102 Sulfolobus solfat... 15899282 71 FLYTYFIsRIPRTG---GDYIWLSRKLNGPLGaimgval----------------------------------------- 106 Sulfolobus solfat... 15899442 69 FLFYLASvSTPRSG---GDYVFQARSSHPLVA------------------------------------------------ 97 Sulfolobus solfat... 15899444 71 IFSYVGS-KVPRVA---ADYVYVSRNLHPALG------------------------------------------------ 98 Sulfolobus solfat... 15899894 68 LIYVFLTeKIPRTG---GDYVWISRSLNGGLGsimalal----------------------------------------- 103 Sulfolobus solfat... 13541618 120 LYDKMGYySIKNNLetfGGPSFIRSAHGRSSLr----------------------------------------------- 152 Thermoplasma volc... 16081619 136 LYDKMHVySLEHDLnalGGPSFIRTAHGRQSLr----------------------------------------------- 168 Thermoplasma acid...
586352 210 vafvgsqtvsraGNILFLVLAASIFSIPLSALIRSPfteggisytgpswqtfhdnllphltkgaagsllkgketfndLFG 289 baker's yeast 11135712 -------------------------------------------------------------------------------- Mycoplasma pneumo... 12643674 91 ----------ckNFMTYLYLPLTFFFMPLYFICSIQd---------------------------------------gFRG 121 Mycoplasma pneumo... 15899059 103 ------llestaFYAIISFFSASSVNSVLLTIGYLN-----------------------------------------HQN 135 Sulfolobus solfat... 15899282 107 ------afnmppFFALSAFFSVSAINSVLLTIGTLN-----------------------------------------SQP 139 Sulfolobus solfat... 15899442 98 ------------FVNYWALWVAFALSLGLYSYLGAQ-----------------------------------------WFA 124 Sulfolobus solfat... 15899444 99 ------------FVGNAGYFLATVPLFMGITGITLQtfg------------------------------------liPLL 130 Sulfolobus solfat... 15899894 104 ------miestaYFALVAFFTSSAINTALTVIGEYQ-----------------------------------------HSP 136 Sulfolobus solfat... 13541618 153 -----------yFISRFSMWIANTSLASFSVIYFVDf----------------------------------------TFT 181 Thermoplasma volc... 16081619 169 -----------yFISRFSMWIANTSLAAFSVIYFVEf----------------------------------------TFN 197 Thermoplasma acid...
586352 290 VFFPATAgifagagmsselrkpsksipkgtlwgllftficyavVVFSMGcsiprrslydevqiiqtissvqWVIFMGEMA 369 baker's yeast 11135712 1 ----------------------------------------------------------------------------MNQQ 4 Mycoplasma pneumo... 12643674 122 LLGLETGa-----------------------------------HFNTSVd----------------------WLIWLALA 144 Mycoplasma pneumo... 15899059 136 SLIYIAE------------------------------------NVIVNPyatptf----------qqrlifYGISAFAFA 169 Sulfolobus solfat... 15899282 140 YLVNLAN------------------------------------NVFTTSnav-----------------laYGLAAVAFL 166 Sulfolobus solfat... 15899442 125 YLFSGLGvfy-------------------------------nnQTLINLgsff---------------tttLGSVIIGII 158 Sulfolobus solfat... 15899444 131 TILGYYThn--------------------------------psLIVVGSqid----------------snpYLIMVIGAV 162 Sulfolobus solfat... 15899894 137 ILLNIAN------------------------------------NVIVDPyvvtptl---------qqsliiYGISALVFV 171 Sulfolobus solfat... 13541618 182 VIDPLVQsi----------------------------------gFSQLDi---------------------DLLSAAIII 206 Thermoplasma volc... 16081619 198 VISPLLAel----------------------------------gLSPIFr---------------------YTAVAGAIL 222 Thermoplasma acid...
586352 370 TSLFSIIVGMLGAAYVLEaiakdniipgleIFAHSPLYSLIFTWILTQLCLFSDVNKIatfitMTFLMtfvvmnlacfLL 449 baker's yeast 11135712 5 LNTTRKSTAARGRMGLVG------------GILLVIGTCIGAGIFFKSERVLQNMGGN-----TTLALl----------- 56 Mycoplasma pneumo... 12643674 145 LIITTYFLTIPPLYAKVGn----------iQNMVVSAVKFIPLVFVPIIGFIVAGTGNgelknVKALVqppqingataSF 214 Mycoplasma pneumo... 15899059 170 IIVLINILHSKWGYKLVT------------GLGMFSMLTVILAMIVMAINAKRFDSLV-----LPLLK----------DF 222 Sulfolobus solfat... 15899282 167 IIILINILRPRWGYTLTS------------ALGMFSLLGTLVAILVLTLNISDFHTVI-----QPFIK----------DF 219 Sulfolobus solfat... 15899442 159 ILIIGAIIASIGKYGWSF------------VFITGIVSILSTIVTFVALALITPSQFSdalssFTGVSn---------AY 217 Sulfolobus solfat... 15899444 163 EIVIMSLIPIFGNKVYRA------------FQWIAIPLALIAAIGMIIVEASVPHSLAia--rLNNFAs---------VY 219 Sulfolobus solfat... 15899894 172 VIILLNIFRAKWGYRVVS------------VLGIFSIATLILAMIVLALNSSDFYSKL-----STLIT----------AN 224 Sulfolobus solfat... 13541618 207 FMVVWFIINAFYGKRFIR------------GIGYTQIGFLIIMVSIIFTDTLDLGFKFs----WNLSG----------LS 260 Thermoplasma volc... 16081619 223 FMVIWFILNAFYGKRYMK------------GIGMAQIVLLIIMVSIIFLDALDLGFMNs----WNLTG----------LL 276 Thermoplasma acid...
586352 450 GIssapnfrpsfkyfnryttAIGALLsvvamlivdgisaSVLFLAMILLFLFIHYfsppkswGDVSQSLiyHQVRKyLLR 529 baker's yeast 11135712 57 --------------------VWLMAG-------------ITVILMGLALVEITAK-------AAFDDLAllSWTQKfTNN 96 Mycoplasma pneumo... 12643674 215 TQlvqag---------ygitRFTGIGag----------mGSFISIAAIFFAYDGF-------YVTAGLQ--SEMRE-PKK 265 Mycoplasma pneumo... 15899059 223 NVtvssn--------lpktiLPYSIS-------------IPATLFLLPLFALYTY-------PWMNAG---PAVSSe--- 268 Sulfolobus solfat... 15899282 220 NLtvql-------------ykgpTFS-------------LSSTFYMIPYFASFAY-------IWLYAG---PAVASe--- 260 Sulfolobus solfat... 15899442 218 NEvist-----------atsNGLNFVsp---------fyGALLAIPVVWYYYVWY-------NLPASWS--GEMKKvKYN 268 Sulfolobus solfat... 15899444 220 ANvsnlyan----vtssnapVPAYYNi------------YNIISLNPVYVVGFSYi------INTIYVA--GEVRN-PKR 274 Sulfolobus solfat... 15899894 225 NLnitips-------srgsfLPSSLS-------------WSATLFLLPFFALYTY-------PWMQAG---PAVAAe--- 271 Sulfolobus solfat... 13541618 261 SF------------------HGNLAS-------------AIIMNTGYLFILFFGY-------QEIQVME--RDSKE-EGS 299 Thermoplasma volc... 16081619 277 TF------------------HANAPE-------------LILINTGYLFILFFGF-------QEIQVMV--RDSKD-ESK 315 Thermoplasma acid...
586352 530 LrqdnikywRPQILLFVDnprtswnlirfcnhLKKGGLYILGHVAVTADFPKQln---elKTQQKawmkirdmaaikafv 606 baker's yeast 11135712 97 T--------FYKACKRFLi------------wIYLPTTFFFMPLYLVQSLQDGl-------------------------- 130 Mycoplasma pneumo... 12643674 266 T---------PWALFLGL--------------LITTLFYLILAVALSINGGLFs------GMEES--------------- 301 Mycoplasma pneumo... 15899059 269 ---------YRGDRVSKL--------------NVFLSLLITGIFVTIGFLEm--------DLIAGyyf------------ 305 Sulfolobus solfat... 15899282 261 ---------IKNKSGIRY--------------NLILGSLLTLIFITVPFLLm--------DVAAGygf------------ 297 Sulfolobus solfat... 15899442 269 S--------LLGIIIAVLf------------iGVYYILFTSLNLHAFGERFLTs-----wSYISTnsln----------- 312 Sulfolobus solfat... 15899444 275 S--------MPISILGTL--------------IITGFIFTAALALEYNQFGYDfttkmmyLSIVQg-------------- 318 Sulfolobus solfat... 15899894 272 ---------FRGRKTVKW--------------NLPIALIITGILVTLAFLEm--------DLIGGynf------------ 308 Sulfolobus solfat... 13541618 300 Ip------iLSQIKHKKYp------------kTKYLPASMYATIAAAGIIQILy------GLAVFsl------------- 342 Thermoplasma volc... 16081619 316 Ip------iISAITGKAYp------------kKRYMPYSMYATIAGAGFIQLLy------ALAVFsv------------- 358 Thermoplasma acid...
586352 607 qvgtGPSliwgirnvfigsglggmKPNITVVGFFDLesyrkhipqsrsqnnLQKQVEIKATVPRSTCSDVkinvplptde 686 baker's yeast 11135712 131 ------------------------RGFGVANHFNTPhd------------wAIWMVIVLLINLWFFFTSG---------- 164 Mycoplasma pneumo... 12643674 302 ------------------------MGKLFNNKRAG----------------QIVFGVVNLMIGIGVLGII---------- 331 Mycoplasma pneumo... 15899059 306 -nlnAFPsa--------------iYNFWTVAMALSLn--------------PIIEWILGLGLIMWNYYVL---------- 346 Sulfolobus solfat... 15899282 298 -nysLYLsg--------------tYNFWTVAIALSRn--------------YALEWFIGISLIAWEFFVM---------- 338 Sulfolobus solfat... 15899442 313 -stvYNDlssm----------gtfTPFFALLVNHS----------------ILLYIVMWIAFWLPNFYSN---------- 355 Sulfolobus solfat... 15899444 319 ---tLPIp----------------TPYLDLLEGIASg--------------NIVLGVLFALASIVQLLMYl--------- 356 Sulfolobus solfat... 15899894 309 -nleAYPtf--------------lYNFWTAAIAVASn--------------PILQWIIALGLIVWNIYIL---------- 349 Sulfolobus solfat... 13541618 343 ---hANTss-------------veQAVIPAIYLASef------------qnKMWALMMAFSFLLATVTTF---------- 384 Thermoplasma volc... 16081619 359 ---hAPYsa-------------veSAVIPAIYIASvf------------qnNIWALGMAISFLLATVTTF---------- 400 Thermoplasma acid...
586352 687 cknetkvnvqqwvqivEDLSLMQSNIAIAHGFknleipnKRdsCFPKktidLYPiqmcgKVEAKGDQPAAITTNFDTYTL 766 baker's yeast 11135712 165 ----------------LSVKWTSVQNVVLLLLk----------VIPLiavvILAlwlgaSAEQMERQPVVPVKDFTAISP 218 Mycoplasma pneumo... 12643674 332 ----------------NGFALWAPRFVEDLLA-------QG--DLPFw--kQVQg----RLNPNK--PVVGVIYCLVLSL 378 Mycoplasma pneumo... 15899059 347 ----------------SYGVLVFSRYVFALSF-------DR--VFPE----KFS-----QLNANG-SPVYAHVFDLTLTL 391 Sulfolobus solfat... 15899282 339 ----------------AFGVVVFARYVFAFSF-------DR--LFPE----VFS-----RLNKQG-SPAYAHLLDFVVTL 383 Sulfolobus solfat... 15899442 356 ----------------PPLVISLTRYLFAWAF-------DR--IMPE----RLA-----DVNEKFHIPLISTIITVIVGL 401 Sulfolobus solfat... 15899444 357 ----------------SAASFVGSRLLFSYAM-------DR--IMPD----FVG-----DVSEKRHVPIKAIILSMIAGL 402 Sulfolobus solfat... 15899894 350 ----------------AYGVIVFARYVFALSF-------DR--VLPT----KFS-----EVNKHG-SPVYAHVFDLSLTL 394 Sulfolobus solfat... 13541618 385 ----------------VPAFMAASRHLRSLSE-------DG--IFPR----PLA-----SLSWVFTFILILFMSFGGTAF 430 Thermoplasma volc... 16081619 401 ----------------VPAFMAASRHLRSLAE-------DG--IFPQ----SFA-----ALSWVFTFVLILFMSLGGTGF 446 Thermoplasma acid...
586352 767 ilqlaAilvtvpewkrthslrVILFVEQEyhrtnetqrmkkllqVLRIDAEVLVVSLDQFRVYNTIVKGDPIVFDYvnsk 846 baker's yeast 11135712 219 ---------------------FFGWFSAMg------------------AIFFAFDGFYVSAAAKTQLKKQKNYRK----- 254 Mycoplasma pneumo... 12643674 379 tvqvlFtvig-------alayLPTVADYKnyvnteidklnsmqwLYSFSDLMATWTSLFTFAFIACAIFGAIVNRK---- 447 Mycoplasma pneumo... 15899059 392 l--------------------FLLIPVFS-----------------IDAAVSLYGASIVGMLYFLAVGISAIIFGR---- 430 Sulfolobus solfat... 15899282 384 v--------------------FLAVPIIS-----------------PNGYEALYSYTPLAIAYLVLVSIAGIRQAL---- 422 Sulfolobus solfat... 15899442 402 i-------------------gVLLYAYVTvi------------sIVDVTVIFEISYGIFALTTALSPFVKKNFFNK---- 446 Sulfolobus solfat... 15899444 403 ig------------------lTVFTLPVTs----------------AGAFLLSSVAVAILMLFPMAILSIAVLKTE---- 444 Sulfolobus solfat... 15899894 395 l--------------------LLLVPAFS-----------------IGAAISLYGATILGSLYFLVVSIAGIAFGT---- 433 Sulfolobus solfat... 13541618 431 lvnitD---------------FMVLVSLS---------------FVALSAMVLKENSKFDRLSVISLITFLMFMIS---- 476 Thermoplasma volc... 16081619 447 lvnitD---------------FMVLIALS---------------IIALTAIALRDRHRFDHVEAISIITFMMFMIG---- 492 Thermoplasma acid...
586352 847 ladnEWWKDLVEARDTLKPkrrfSTIEPQTIAKQFTQsrkytsgvqklgvsFTMNTRMPTnridtpcesedsdldtdlts 926 baker's yeast 11135712 -------------------------------------------------------------------------------- Mycoplasma pneumo... 12643674 448 ----TKKITIANPKRYFLPaawiAVVVNCISVFVTIIepf---------inLFLLFGYDEtvahtv-------------- 500 Mycoplasma pneumo... 15899059 431 ----KIRSGLMKIA----------GILMTVYFVYLTYe-------------AARNPLFGf-------------------- 463 Sulfolobus solfat... 15899282 423 ----SERNLGMLIS----------ALLSIGFLGFMGYe-------------AFTNPYFGv-------------------- 455 Sulfolobus solfat... 15899442 447 ----VVHIKNISGIPLVSLi--gFPEFGFLLFALYQTwg----------npVLLPINFP--------------------- 489 Sulfolobus solfat... 15899444 445 ----KN--ENKIRIIAALS----IIYLIYTFYQYLTVp-------------AIGADSIVGy------------------- 482 Sulfolobus solfat... 15899894 434 ----KDRNYVLSIA----------GIISAAYFAYLTYv-------------AATNPDFGf-------------------- 466 Sulfolobus solfat... 13541618 477 ----AISIYMIDRIVVVFG----VIALIASFLLYDILr------------lKLFGLEVLG-------------------- 516 Thermoplasma volc... 16081619 493 ----AVSIYFSDKSVVILG----IMAIVAAYLLYDIMk------------lSMMGMELFG-------------------- 532 Thermoplasma acid...
586352 927 irdafsastnisvgkdlttksktgsdrtnllvknlqsdvstqslrpvfssntlprtrvvEDGTgeqptlIPIAEPDLSNG 1006 baker's yeast 11135712 -------------------------------------------------------------------------------- Mycoplasma pneumo... 12643674 501 ------------------------------------------------------lgndfIELNelvigrVMLIVVLVFFA 526 Mycoplasma pneumo... 15899059 464 ----------------------------------------------------------sTTSG--------VNVTTLSFV 477 Sulfolobus solfat... 15899282 456 ----------------------------------------------------------iSDNG--------VPYWPGIAY 469 Sulfolobus solfat... 15899442 490 -----------------------------------------------------------TILSl-----VIIYTSGIMIY 505 Sulfolobus solfat... 15899444 483 ----------------------------------------------------------gILAG-------SIVILFIIFY 497 Sulfolobus solfat... 15899894 467 ----------------------------------------------------------mTSSG--------PNLITTIFV 480 Sulfolobus solfat... 13541618 517 -----------------------------------------------------------AFFG------TLSLLSTLVMK 531 Thermoplasma volc... 16081619 533 -----------------------------------------------------------FTLG------ILSLLPLIVFR 547 Thermoplasma acid...
586352 1007 NGTGSGigngnklkkpVLPELSPCCSKDSLVTAmqnL 1043 baker's yeast 11135712 ------------------------------------- Mycoplasma pneumoniae 12643674 527 IISFLPvyve---dqyHKRKFGSLANYQQYVQQhlaH 560 Mycoplasma pneumoniae 15899059 478 LGSFI-----------AGIVIWNITRYVNSKK----G 499 Sulfolobus solfataricus 15899282 470 ITSLIG----------LGVITFVSSYYYRKKS----G 492 Sulfolobus solfataricus 15899442 506 AISYIIn---------KKRGIHMNLIFEEIPPE---- 529 Sulfolobus solfataricus 15899444 498 VAKFIR----------ARQGIDFNLIFKEIPPE---- 520 Sulfolobus solfataricus 15899894 481 VGTFI-----------AGALAYIISKIVHKRK----G 502 Sulfolobus solfataricus 13541618 532 SSASPSvliigniavrSPYNLLFLQISVLVLVVillA 568 Thermoplasma volcanium 16081619 548 TEASPTiriignilirSPYNLIYIQISLLIMVVvlmL 584 Thermoplasma acidophilum
Jiyao W et al.(2023). "The conserved domain database in 2023.",