Conserved Protein Domain Family
IlvD

?
COG0129: IlvD 
Dihydroxyacid dehydratase/phosphogluconate dehydratase [Amino acid transport and metabolism, Carbohydrate transport and metabolism]
Dihydroxyacid dehydratase/phosphogluconate dehydratase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Statistics
?
PSSM-Id: 439899
Aligned: 544 rows
Threshold Bit Score: 615.481
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
WP_045531164   1 M-PTYRSKTSTAGRNMAGARALWRATGMKDGDF-DKPIIAIANSFTQFVPGHVHLKDLGQLVAREIEAAGGVAKEFHTIA 78 
WP_013254198   1 ----MRSDKMKLGSKRAPHRSLMKALGLTDREI-AGPIIGIASSASELIPGHMHLAQVEDAVKAGVRMAGATPLRFSTIG 75 
WP_025392737   1 ---MRRSDIMLKGPERAPHRSLFKADGFTDEEL-SRPIIAIANSSNDIVPGHVHLKTLVEAVKAGIYMAGGTPIEFNTIG 76 
WP_013682167   1 --MARRSDVMLRGPERAPHRSLFKADGYTDIEL-NRPIIAIANSYNTIVPGHVHMQQLVEAVKYGIYMAGGTPIEFNVIG 77 
WP_041310187   1 ---MMRSDNLKKGDRRAPHRSLLKGLGFVNEEM-DKPIIGIANSFNEIIPGHVHLQTLVQSVKDGIRMAGGVPMEFNTIG 76 
WP_072514774   1 M--DLKSKKVYAGPERIEARALLYATGKLEKDIgKKPLIGVVNSFNEIVPGHFHLRSLAEAAKLGVAAGGGIPVEFPAIA 78 
WP_041225236   1 --MPMRSDAIKKGLARAPHRSLLKADGFTDEEL-ARPLIAVVSSRNEIIPGHLHLQTIADAVSAGIRMAGGTPAQVNTIG 77 
WP_041760992   1 MkGKGRSNNLTRGEARAPHRSLLKGLGFTSEEM-DRPIIGIANSFNEIIPGHVHLKNLVQAVKDGIRMAGGVPMEFNTIG 79 
NP_228361      1 ----MRSDVIKKGLERVPHRSLLKALGITDDEM-RRPFIGIVSSWNEIIPGHVHLDKVVEAVKAGVRMAGGVPFVFPTIG 75 
WP_015760823   1 --MQLRSDAVRCGTARAPHRSLLKADGITDEEM-ERPLVAVFNSRNDIIPGHNNLDKIAEAVKAGIYMAGGVPFEISTIG 77 
WP_045531164  79 VDDGIAMGHDGMLYSLPSREVIADSVEYMVNAHCADALVCISNCDKITPGMLMAAMRLNIPVVFVSGGPMEAGkvq-rsA 157
WP_013254198  76 VCDGIAMDHKGMYYSLPSRELIADSIEIVAEGHPFDGMVFISNCDKITPGMLMAMGRLNIPSVLISGGPMLAGny---hG 152
WP_025392737  77 VDDGIAMGHLGMHYSLPSRENIADAVEIMVNAHPVDGLVILPACDKIVPGMMMAAARVNIPTIMISGGPMLAGky---qG 153
WP_013682167  78 VDDGIAMGHLGMHYSLPSRELIADSVETMVNAHPVDGLVILPACDKIVPGMMMAAARVNIPTIMISGGPMLAGrf---nG 154
WP_041310187  77 ICDGLAMNHIGMKYSLVTRQIVADSIEATAMATPFDAIVFIPNCDKVVPGMLMAAARLNIPSIFISGGAMLAGvy---kG 153
WP_072514774  79 ICDGIAMSHTGMHYPLASRELIADSIESMALAHGLDGLVLIPNCDKIVPGMMMAACRLNIPSIVVSGGPMATGhf---hK 155
WP_041225236  78 ICDGIAMNHEGMRYSLASREVIADSVECVVQGHRFDGMVLIPSCDKVVPGMLIAACRLNIPTVVVTGGPMLAGrd--qdG 155
WP_041760992  80 ICDGLAMNHIGMKFSLVTRNIIADSIEAVAMATPFDAIVFMPNCDKVVPGMLIAAARLNIPSIFVSGGAMLAGvy---kG 156
NP_228361     76 ICDGIAMDHRGMKFSLPSRELIADSIEIVASGFPFDGLVFVPNCDKITPGMMMAMGRLNIPSVLISGGPMLAGry---nG 152
WP_015760823  78 VCDGIAMNHDGMHYSLVSREAIADSLECAVQGHAFDALVCIPNCDKIVPGMLLGALRVNIPTVFVSGGPMLPGkqpggcG 157
WP_045531164 158 pgsQtiEFKKLDLVDAMVMAADDQVSDAELAEVERNACPTCGSCSGMFTANSMNCLTEALGLSLPGNGTVLATHSDREQL 237
WP_013254198 153 ---K--SLDLISVFEAVGRHAQGNIDDDELAAIESYACPGAGSCSGLFTANSMNSLAEVLGLALPGNGTIPAVDSGRIRL 227
WP_025392737 154 ---K--DIDLAQAFEAVGKYISGSINEEELLEIENIACPSCGSCSGMYSANSINCLSEALGLSLPGNGTIPAVYAARVRL 228
WP_013682167 155 ---T--DIDLAQVFEGVGKYLSGQITEEELKKIEDIGCPSCGSCSGMYSANSINCISEVLGLSLPGNGTIPAPMAARVRL 229
WP_041310187 154 ---K--KIGLSNVFEYVGQFESGKMTAKELNMVEDMACPTCGSCSGMYTANTMNCLTEALGMGLPGNGTVPAVFSERLRL 228
WP_072514774 156 ---E--TADYSTCIEQTAAYKLGEKTEEQMEEYAHSACPSCGSCAGMFTANSMNCLSEVLGLALPYNGTIPSYYGARLAL 230
WP_041225236 156 ---S--ETDLNTLFDAVGAVTAGTMSEDKCKWYEDSACPTCGSCSGMFTANSIGCLCEALGIALPGNGTIPAVYSERVRL 230
WP_041760992 157 ---K--KIGLSNVFEAVGEYEAGLITKRELNSVEEMACPTCGSCAGMYTANTMNCLTEALGLGLPGNGTVPAVFSERIRL 231
NP_228361    153 ---R--DIDLITVFEAVGGYKVGKVDEETLKAIEDLACPGAGSCAGLFTANTMNSLAEALGIAPRGNGTVPAVHAKRLRM 227
WP_015760823 158 ---P--TTDLNTLFDGAAQVMNGDMSEAELKYYEDTACPTCGSCSGMFTANSMNCLCEALGIALPGNGTVPAVYSERIRL 232
WP_045531164 238 FRRAGRLIVELARRhyegddaSVLPRSIASFEAFENAVTLDIAMGGSTNTVLHLLATAREAEVHFTMADIDRLSRRVPTL 317
WP_013254198 228 AKEAGMAVVRLVKE-------DICPRNIATEDSFMNAVAADLALGGSSNTALHLPAIAKAFDVDFSIDNFDLLGRRIPHL 300
WP_025392737 229 AKLAGAKIVELVEK-------NIKPRDIITIDSIKNAIAVDMAMGCSTNTVLHLLAIAQEANIELSLDIFNEISDKTPDL 301
WP_013682167 230 AKIAGMKIVELVNR-------GIKPRDIMTKEAFYNAIIADMAMGCSTNTVLHLLAIAQEAKVNLTLDDFDRFTDKVPDL 302
WP_041310187 229 AKKAGMQILEILKA-------DLKPKDIMTKEAFVNAVAVDMALGGSTNTALHLPAVAHDAGVKLTIDDFNEIAARVPQL 301
WP_072514774 231 ARTAGERAVELVRE-------NLCPLDIVTEASFTNAIVVDMAIAGSTNTTLHLPAIAHECGFDLPLEKFDEISRKTPNL 303
WP_041225236 231 AKHAGMKVMDLVAN-------NICALDIINEHALHNGMALDMAFGGSTNTMLHLTAISHAAGCPVSMDDWDAICQHTPNI 303
WP_041760992 232 AKKAGMQIMEVLKA-------DVRPKDILTREAFENAVAMDMALGGSSNTALHLPAIAHEAGIKLTLEDFNEIAKITPQL 304
NP_228361    228 AKEAGMLVVELVKR-------DVKPRDIVTLDSFMNAVMVDLATGGSTNTVLHLKAIAESFGIDFDIKLFDELSRKIPHI 300
WP_015760823 233 AKHAGMKVMELLEQ-------GICARDIVSEAAIHNAMECDMAFGGSTNTVLHLTAVAREAGHPITMDDWDAASARTPHL 305
WP_045531164 318 CKVAPNTdRYHIEDVHRAGGIMAILGELDRAGLLHAGCGTVHSPTLAAALAQWDIarapapapevqtfyraapggvptqv 397
WP_013254198 301 CNLSPVG-KHHIQDLEAAGGIGAILSRLNELGELKRDARSVTGKTIGEIADASRV------------------------- 354
WP_025392737 302 CSFSPVG-PYHLEDLDNAGGVMAIMSRLDSIGLIKRDCITVTGATIYDSYKNAKV------------------------- 355
WP_013682167 303 CAFSPVG-PYHLQDLDEAGGMMALLNRLEPLRLLNHDCITVSGKTIYESYKATRV------------------------- 356
WP_041310187 302 CKLSPSG-EYFIEDLYRAGGVTAVMRRLLENGELDGTQKTVALKTQEELCKEAYI------------------------- 355
WP_072514774 304 CHISPSG-DKFMFDLYLAGGVPAIMHELAKRDLLDTKQINVNGKTIAENIAHAES------------------------- 357
WP_041225236 304 TRIAPAG-PLHIEDLNAQGGVAAVIGELGRAGLLDEAALTCHG-TMREWIDACPT------------------------- 356
WP_041760992 305 CKLSPSG-EHFIEDLYRAGGVTGVMKRMLENGRLHENTKTVALRTQGELAKEAFI------------------------- 358
NP_228361    301 CNISPVG-PYHIQDLDDAGGIYAVMKRLQENGLLKEDVMTIYLRKIGDLVREAKI------------------------- 354
WP_015760823 306 VKLQPSG-PRPLSDLYEVGGVPVVMHELAELDLLDRRAITCMGPLDEYLRTCTKP------------------------- 359
WP_045531164 398 afsqsqrwpsldtdRANGCIRNLEHAYSRDGGLAVLYGNLALDGCIVKTAGVDQsmFeaeqlryttsvptstlrAFEGPA 477
WP_013254198 355 --------------WDDEVVRPVGRPYHSEGGLAVLHGSLAPDGAVVKLAGVPEalR-----------------VHEGPA 403
WP_025392737 356 --------------KNNNIIRPVDKPYYPKGGLSILKGNLAPFGAVLKQSGVSAkmD-----------------HFVGKA 404
WP_013682167 357 --------------YRDEVIRPLDKPYYPRGGLTILKGNLAPDGAVLKQSGVDTsmN-----------------KFVGRA 405
WP_041310187 356 --------------NDEDVIKPWDKPAYAGGGLAVLKGNLAELGSVVKAGAVADemQ-----------------VHSGPA 404
WP_072514774 358 --------------TDASVIRPIDDPFGKEGGLAVLKGNIAPGGCVVKSAAVRPemM-----------------HHRGKA 406
WP_041225236 357 --------------PDGEVVHTIENAYSAQGGLRVLRGNLAPHACVVKQSAVSAamR-----------------QHAGPA 405
WP_041760992 359 --------------NDDDVIKPWNKPAYKTGGIAVLKGNLAPDGCVVKEGAVDPemL-----------------QHTGPA 407
NP_228361    355 --------------LNEDVIRPFDNPYHKEGGLGILFGNLAPEGAVAKLSGVPEkmM-----------------HHVGPA 403
WP_015760823 360 --------------ADGEVCRTHDNPFSPVGALKVLHGNIAPDGAIVKKSAVDPsmL-----------------THTGPA 408
WP_045531164 478 RVFESQDAAVEAILGDRIVPGDVVVIRYEGPRGGPGMQEMLYPTSYLKSKGLGKVCALLTDGRFSGGTSGLSIGHASPEA 557
WP_013254198 404 VVYEDGEVATEAILAGKVKSGDVVVIRNEGPKGGPGMREMLSPTSAIVGLGLIEKVVLITDGRFSGGSTGAVIGHVSPEA 483
WP_025392737 405 RVFDSEEEATKAIFSKQIKEGDCVVIRYEGPAGGPGMKEMLQPTSAIAGMGLDTKVALITDGRFSGATRGLSIGHISPEA 484
WP_013682167 406 RVFDSEEEALKAIFGKQINKGDVVVIRYEGPAGGPGMKEMLQPTSAIAGMGLDKDVALITDGRFSGATRGLSVGHIAPEA 485
WP_041310187 405 KVYNSEEEAVDGILGGKVKSGDVVVIRYEGPKGGPGMREMLTPTSVIAGMGLDKEVALLTDGRFSGATRGASIGHVCPEA 484
WP_072514774 407 KVYTSMEEATAGIFNGEVEHGDVVVIKYEGPKGGPGMREMLTPTSAIVGMHLDHDVALITDGRFSGATRGAAVGHVSPEA 486
WP_041225236 406 QVFDSEEAACEAIFAGKIVPGAVVVIRYEGPSGGPGMREMLTPTSAIFGMGLADSVALITDGRFSGATKGPCIGHVSPEA 485
WP_041760992 408 KVFNSEEEAVEAIVGGKIIAGDVVIIRYEGPKGGPGMREMLSPTAMIAGMGLDKDVALITDGRFSGATRGASIGHVSPEA 487
NP_228361    404 VVFEDGEEATKAILSGKIKKGDVVVIRYEGPKGGPGMREMLSPTSAIVGMGLAEDVALITDGRFSGGSHGAVIGHVSPEA 483
WP_015760823 409 RCFDSEEEACAAINGGRVEAGDVVVIRYEGPKGGPGMREMLTPTSSIVGMGLSTSVALITDGRFSGATKGPAVGHVSPEA 488
WP_045531164 558 AAGGTIGLVREGDRIRIDIAQRRIELLVSEDELAQRRLQqdalgWK------PaaPRPRKVSAALKVYAKFVLSADKGAV 631
WP_013254198 484 ANGGPIGLVQEGDRIRVDFNKRSLDLLVEEDEKKRRAGA-----LAeasaekPv-AAKHNPDGYLARYSIFVGSAAEGAI 557
WP_025392737 485 AKGGLIGLIEENDLIEINVPEKTINLLVDEKVIEERKKH-----FK------P--KPPKITTGYLARYARLVQDAHLGAV 551
WP_013682167 486 ARGGLIGLIEEGDKIEFDVENKKMNLLVDDKTIQERKKN-----FK------P--KPPKIREGWLARYAKMVGPASKGAV 552
WP_041310187 485 AVGGTIAVVRDGDIIEIDIPNRTLNVKLSDEEIAARKAE-----LK------P--YEPEV-TGYLKKYALHVGSAVNGAI 550
WP_072514774 487 MEGGPFAIIEEGDIIEIDIPNRRIHLDCSDEEIQARLAK-----WK------A--PAPKVQKGYLVRYARMVSSANRGAV 553
WP_041225236 486 AAGGPIAFVHDGDVIRIDLDAGTIELDVPADELARRRAA-----WQ------A--PKPKYTTGVLARYAKLVSSADKGAY 552
WP_041760992 488 ASGGNIAIVQDGDIIEIDIPSRTINIKISDEEIEARKAK-----LE------P--FKIEV-KGYLRKYAMHVSSADRGAI 553
NP_228361    484 AEGGPIGIVKDGDLIEIDFEKRTLNLLISDEEFERRMKE-----FT------P--LVKEVDSDYLRRYAFFVQSASKGAI 550
WP_015760823 489 AAGGPIALIEEGDTVTVDIEGGALTLGVDDAELERRRAA-----WT------P--PAPKHDHGVLAKYAKLVSSADKGAY 555
WP_045531164 632 RDL 634
WP_013254198 558 YRK 560
WP_025392737 552 LR- 553
WP_013682167 553 LEy 555
WP_041310187 551 EEY 553
WP_072514774 554 VE- 555
WP_041225236 553 Fg- 554
WP_041760992 554 EIL 556
NP_228361    551 FRK 553
WP_015760823 556 VS- 557
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap