4G9B


Conserved Protein Domain Family
PGMB-YQAB-SF
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TIGR02009: PGMB-YQAB-SF 
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beta-phosphoglucomutase family hydrolase
This subfamily model groups together three clades: the characterized beta-phosphoglucomutases (including those from E.coli, B.subtilus and L.lactis, TIGR01990), a clade of putative bPGM's from mycobacteria and a clade including the uncharacterized E.coli and H.influenzae yqaB genes which may prove to be beta-mutases of a related 1-phosphosugar. All of these are members of the larger Haloacid dehalogenase (HAD) subfamily IA and include the "variant 3" glu-asp version of the third conserved HAD domain (TIGR01509).
Links
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Statistics
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PSSM-Id: 213673
Aligned: 11 rows
Threshold Bit Score: 228.766
Created: 8-Oct-2014
Updated: 25-Oct-2021
Structure
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Program:
Drawing:
Aligned Rows:
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Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
4G9B_A            5 LQGVIFDLDGVITDTAHLHFQAWQQIAAEIGIS-----------ID--A--QFNESLKGISRDESLRRILQHGg------ 63   Escherichia...
CMCP6:VV2_0527    9 YTGFIFDMDGTLIDTMPAHLIAWEKTAEHFQFP-----------FE--Q--QWIHSLGGMPSFKIAAEINKKY------- 66   Vibrio vuln...
P44004           10 YEGLIFDMDGTLIDTMPVHAQAWTMVGKKFGYE-----------FD--F--QIMYNFGGATVRTIAGEMMKAA------- 67   Haemophilus...
WP_000775779      3 LQGVIFDLDGVITDTAHLHFQAWQQIAAEIGIS-----------ID--A--QFNESLKGISRDESLRRILQHGgk----- 62   Enterobacte...
WP_010965902      3 IKAVIFDLDGVIVSTDEYHYRAWKAMADEEGIY-----------FD--K--RINERLRGVGRMESLEIILEKAk------ 61   Clostridium...
WP_010925436      8 IKAIIFDLDGVIVETASLHFLAWKHEVAKLGIN-----------FT--K--EQNTSLKGLNRIDTLKAILKLhn------ 66   Mycoplasma ...
WP_010899989      5 FEAVIFDMDGVIADTVGLHYEANQHIAKKLSVT-----------FS--E--EMNQSLQGLSREKTVRAICDLtg------ 63   Bacillus ha...
WP_000273283      5 YAGLIFDMDGTILDTAPTHRKAWREVLGHYGLQ-----------YD--I--QAMIALNGSPTWRIAQAIIELN------- 62   Shigella fl...
WP_010931708      9 PKAFIFDMDGVLVDNMRMHAQSWVDLFADYGLSg----------LDp-E--RYLVETAGMKGLDVLRYFLDp-------- 67   Chlorobacul...
WP_006769952     43 ISAVLFDMDGVVTNTALIHATAWKSLFDDVIADrape----qelFN--KetDYRAYVDGLSREDGVRSFLASRgvdipeg 116  Corynebacte...
Q50725           23 VRACLFDLDGVLTDTASLHTKAWKAMFDAYLAEraertgekfvpFDpaA--DYHTYVDGKKREDGVRSFLSSRaieipdg 100  Mycobacteri...

4G9B_A           64 ---kEgdFNSQErAQLAYRKNLLYVHSL-Re-LTvNAVLPGIRSLLADLRAQQISVGLASVS--LNAPTILAALELREFF 136  Escherichia...
CMCP6:VV2_0527   67 ----G--LSLVA-MDVSQFKMAAFAALD-E--HG-DAIECTHRVLEKYLGQKKIAVGTGSQR--ESAIRLLAKANLLDKL 133  Vibrio vuln...
P44004           68 ----N--MPLDRiEDVLAAKRELSYQLI-P--TQ-SKLLPTFEIVKSFHQKKPIALGSGSHR--KIIDMLMDKLAIAPYF 135  Haemophilus...
WP_000775779     63 ---eGd-FNPQErAQLAYRKNLLYVHSL-Re-LTvNAVLPGIRNLLAELRAQQIPVGLASVS--LNAPTILAALELREFF 134  Enterobacte...
WP_010965902     62 ---kT--YNTKEkIQMTERKNFIYRELL-Ne-LTpKHILKGVMNVLETLRAKNIKIAIGSSS--KNTSIILEKIKLDKYF 132  Clostridium...
WP_010925436     67 ---yK--LSDEKiEEIAQSKNQYYQRLL-DqeLNsSTILPNIKNFLDQAKKNNLKLALASSS--HNAKFILKKVELLSYF 138  Mycoplasma ...
WP_010899989     64 ---eE--VSDEQvKQLSELRNEQYQRLIaE--LTpADALPGIYSFIRELKEKKVSIALASAS--TNAPRVLSRLQLIDAF 134  Bacillus ha...
WP_000273283     63 ----Q--ADLDP-HALAREKTEAVRSML----LDsVEPLPLVEVVKSWHGRRPMAVGTGSES--AIAEALLAHLGLRRYF 129  Shigella fl...
WP_010931708     68 ----S--ISPEKaDRLTELKDILYRVMN-R--NA-IVAMPGLETFLDRAANAGIRLGIGTGAgpKNIDYVLGLTGLTSRF 137  Chlorobacul...
WP_006769952    117 saedG--PDEVTiHGLAARKQGYFDEAL-D--RQgVEVFPDTLQLLKRLKKEGIPAALVTSS--RNSGPILDTAGITDLF 189  Corynebacte...
Q50725          101 spddP--GAAETvYGLGNRKNDMLHKLL-R--DDgAQVFDGSRRYLEAVTAAGLGVAVVSSS--ANTRDVLATTGLDRFV 173  Mycobacteri...

4G9B_A          137 TFCADASQLKN----SKPDPEIFLAACAGLGVPPQACIGIEDAQAGIDAINaSGMRSVGI 192  Escherichia coli K-12
CMCP6:VV2_0527  134 DALVSATEVQN----HKPHPDTFLLAAQQLGLPANECVVFEDTELGKQAAHaAKMDCVMV 189  Vibrio vulnificus CMCP6
P44004          136 NAIVSADDVKE----HKPHPETFLRCAELIQANPSRCIVFEDADLGVQAGLsAGMDVFDV 191  Haemophilus influenzae Rd KW20
WP_000775779    135 TFCADASQLKN----SKPDPEIFLAACAGLGVPPQACIGIEDAQAGIDAINaSGMRSVGI 190  Enterobacteriaceae
WP_010965902    133 DAVADGREIKK----SKPNPEVFLLAAKKLKVSPEECLIVEDADAGVEAAIaGGMKVLAV 188  Clostridium acetobutylicum
WP_010925436    139 DFIVNPSEIKN----GKPNPEIFLKALEGLNLKASEAIGIEDALAGIYGLRqAKIFAIAI 194  Mycoplasma pulmonis
WP_010899989    135 DVIVDVQKVRR----GKPDPEIFLTAAQLLGVSSNRCVAIEDGEAGLTGILqTDMFAVGV 190  Bacillus halodurans
WP_000273283    130 DAVVAADHVKH----HKPAPDTFLLCAQRMGVQPTQCVVFEDADFGIQAARaAGMDAVDV 185  Shigella flexneri
WP_010931708    138 EVVVGAHMVRH----GKPHPETFLQVAERLGADPASCIVFEDALPGAEAAAaAGMSCVAV 193  Chlorobaculum tepidum
WP_006769952    190 ATRVDGNDILEqglaGKPAPDPFLAAARQLGARPEQCVVLEDSSAGVKAAH-DGCFGLVI 248  Corynebacterium efficiens
Q50725          174 QQRVDGVTLREehiaGKPAPDSFLRAAELLGVTPDAAAVFEDALSGVAAGR-AGNFAVVV 232  Mycobacterium tuberculosis
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