Conserved Protein Domain Family
ComEC

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COG2333: ComEC 
DNA uptake channel protein ComEC C-terminal domain, metallo-beta-lactamase superfamily [Intracellular trafficking, secretion, and vesicular transport]
Statistics
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PSSM-Id: 441904
Aligned: 820 rows
Threshold Bit Score: 93.7688
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_094998887   1 MIIKFLEAHKGDSILISHQddegTSRNILIDGGMSSTyfNSSynqyGQLHLEIE--KIkkrkEKIDLLILSHIDNDHIEG 78 
WP_012675916  21 LDIFFIDVGEGEATLIVTP----DNRNILIDTGNL----ITG----HTVVKFLSskNI----NTLDRLIITHPHPDHSGG 84 
WP_125669780  40 LEVKLLDVGQGDAILLRN-----QAVAILVDTGDYKN----S----DILVRRLKtlGV----RKLDALIITHHHLDHLGG 102
WP_012686189  52 LIVTYLALPHGESTLLRMP----GGKTMLIDTGTAEDw--------PILSARLAelKI----TRLDYVVLTNDQPEHMGG 115
WP_021718922  69 LAVTALDIGQGDSILVQM-----QGKNILIDSGDRSE----A----ARLLTKLEenHV----EQIDMLIATHPHADHIGG 131
WP_112181161  37 LYVSFLNIPDGEATIIQTP----DGKNFLINTGSKESr--------LELWKQLKelHV----EKLDGLILTKQTEEYCGN 100
WP_012574759  41 MAIVFLPLSDGEATLFKHA----SGKTVLLNTGAPHTe--------RELKRWLEhfRI----TEIDELLLTSDDREYIGN 104
WP_075938857  52 LVIRCLDIGQGDATLISW-----QGKWTLIDTGDVEH----R----SALTQYLDryGV----KEVENLIITHPDGDHLGG 114
WP_007957855  38 LTVKVLDIGQGDAILIRA-----AGQTVLVDTGDTGT----K----DKLAAYIKkeGI----TTIDKVIITHPHADHLGG 100
WP_126310629  30 LTVKVLDVGQGDAIFIRTP----E-QTVLIDTGDIPA----R----DKLLAHLRnqGI----SALDKVIITHPHADHLGG 92 
WP_094998887  79 LLKWFSTDAkaynlVGQVWFNSGksiaqffkkeenndlrlnlkvPN-TtytGvA--EaiEF----EDYLLKHK-IwdK-K 149
WP_012675916  85 VFAVIQNVN-----VIQKHDNGQ---------------------SL-N---T-NdcK--DFyiwyAQIFRT-G----KyS 126
WP_125669780 103 VIKILNNFD-----VKNFYDNGI---------------------VNpQ---S-EisK--DV----EKLILN-GiL--SrQ 143
WP_012686189 116 FASLSQQVL-----VNAVILPKL---------------------IA-P---S-IrhV--VL----LRS-NQKQ-M--E-- 152
WP_021718922 132 MKAVLNRFP-----VKHVYDSGQ---------------------NY-K---T-KmyN--DF----RLQIEKEQ-I--PfE 171
WP_112181161 101 IDQIHENFD-----VQNVy------------------------------------yA--NS----EKQLLTGI-T--NkT 130
WP_012574759 105 VKWIEQTYG-----PKVV-------------------------------------------------------------S 118
WP_075938857 115 AYAVLKHVP-----VRYVFDDGL---------------------TK-T---N-AiyR--TY----LKTLDKKG-L--RpY 154
WP_007957855 101 MSSILENFK-----VNQIYDSGQ---------------------TT-T---T-AlyR--KY----LSLVQSKK-I--PfS 140
WP_126310629  93 MPGLLETFT-----VKQIFDSGQ---------------------TT-T---S-GlyR--QY----LGAVQKKN-I--PfK 132
WP_094998887 150 IIRQGDEFAL-FGVQLKILSPDNSQLkklvgeynkktgdpvytsgkkedwaknlkdiiqketldsfrfkqDTSvKNGSSI 228
WP_012675916 127 VLKKGDRIIY-GKVTLEVLSPEQl-----------------------------------------------TNdWNENSL 158
WP_125669780 144 ILSAGQKLEFaDNINLKFLAPASKNg-------------------------------------------fPEKdLNNNSL 180
WP_012686189 153 -AEQGQVLTLeQDISMEVLLPDEp----------------------------------------------LFLsPQNNSL 185
WP_021718922 172 VLRGGQEVPVnEMVKLKVLSPQTLYk-------------------------------------------gTPSdTNNNSL 208
WP_112181161 131 MWKKDDQIKLgSALNIHVLQTNTa-----------------------------------------------------GEM 157
WP_012574759 119 EWKEQKVYEPfPHFRMQPLYIDN------------------------------------------------------GDV 144
WP_075938857 155 VLTQGMQVDLgDGVYLDVLGPTENVMyk-----------------------------------------kGMPdYNNHSI 193
WP_007957855 141 VLTAGTEIVIaNDIKLKILAPEKPFI--------------------------------------------KDSeLNNNSI 176
WP_126310629 133 VVTAGELIDLgGGVTLKVLAPGKPFIt------------------------------------------gSDSdLNNNSI 170
WP_094998887 229 TVLLTYAEKNFLFLADSHPDRVLKSLQElgyskE-KP-IPVELFQISHHGSKSNMHKELLEVVKTNKYVISTdS---SSH 303
WP_012675916 159 VIMLIYGKVRILLMADANKKTEKFLIKK-----Y-RK-LKADLLKVGHHGADDVLLEEFLNRVNPEYAVISI-Nk-nNIR 229
WP_125669780 181 VFKLQYGEFSMLFTGDIEAKTENDLVSRy----G-KK-LQSTVLKVAHHGSSTSSTYNFLKAVQPQLALISC-Gd-kEKY 252
WP_012686189 186 VFRLTHGQLRFLFMSAVNEKAEERLLER-----Q-NDrLKAEVLKVAGQGSNQGSSQPFLTKVDPQVAIIQT-GrsrDQM 258
WP_021718922 209 VLRLEYKDFAMLLTGDIQAEVERDLLQT-----DpEA-LQAQVLKVAHHGSKTSSINEFLAAVKPKIAVISS-Ge-gNKY 280
WP_112181161 158 TFLIEFGKNSILYMSVNDPDSDKGLEAY-----N-LQ--S-EIIKIADYGQSNSPSAKLLQKMDPHISIVf-----nQEA 223
WP_012574759 145 TMSIQYGRLRLLYMAHASDDVERKLMTM-----P-LS--DVNILKIAHFGVNDYPRTSFLKHVDPQVAIIf-----kKHG 211
WP_075938857 194 VMKLVANQFTMLFTGDAEKCQEHELLQAh----G-KK-LAATVLKVGHHGSKTGTTKSFLAAVRPQVATISS-Gr-gNPY 265
WP_007957855 177 VAKLIYHDFSMLLTGDAEKESEERMLKKy----K-TE-LKSTILKAGHHGSNTSSSVSFLKAVAPEAAIISL-Ga-nNDY 248
WP_126310629 171 VTQLVFGGFSMLLAADAEQPAEDRMLKKy----S-SG-LNSTILKSGHHGSRTSSSMPFLRAVNPEVAIISA-Gv-nNEY 242
WP_094998887 304 GHPHKATLARIISVNpQavIyF-NYeNvkKSIfTe-qDlndfPnfEtkliSeYPVS 357
WP_012675916 230 GYPSERVINMLVNKGvK--L-YiTFrD--GTV-HfrsD----G--E----K-LWpE 268
WP_125669780 253 NHPNKKVLGTFEYLQiP--V-KvTSqN--GEI-TlrtD----G--E----K-YQIM 291
WP_012686189 259 KDGQTEVMERLGESWaE--T-YvTShD--GSI-TilsN----G--K----E-YRIL 297
WP_021718922 281 KHPSPEVVQRLYNLQaD--V-FnTAlC--GDI-IiksN----G--K----T-CDIT 319
WP_112181161 224 GTPNKDLMERLNESWiD--V-YqLKqV--GTT-IirmD----L--N----D-YEII 262
WP_012574759 212 SWPNERLLERLYAAWiD--C-YeTNrF--GVI-VvkcN----L--E----E-YDVM 250
WP_075938857 266 GVPHAPVLERLQKRGiR--I-YrTDrN--GTI-TvrtD----G--S----T-YTVE 304
WP_007957855 249 HHPHPSTLKKYGEAKaK--V-YrTDtD--GTV-TinsD----G--K----T-YTIT 287
WP_126310629 243 HHPHPATLKKYADRKiK--V-YrTDtD--GTV-TitsD----G--K----S-YQIS 281
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