1UM9


Conserved Protein Domain Family
AcoA

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COG1071: AcoA 
TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha [Energy production and conversion]
TPP-dependent pyruvate or acetoin dehydrogenase subunit alpha is part of the Pathway/BioSystem: Pyruvate oxidation
Statistics
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PSSM-Id: 440689
Aligned: 883 rows
Threshold Bit Score: 211.923
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1UM9_A        20 GEEG-------EwlgdfpL-D-LEGEKLRRLYRDMLAARMLDERYTILIRTGKT-SFIAPAAGHEAAQVAIAHAIRP--G 87 
WP_084179654  42 KTESpaetpqaSr-----PrDlLSREDCLEIYRQLYLARYFDVRLIKEKKRGNLtGTLYSSHNQEAIIVGSLFGLKP--T 114
WP_015942447   1 -----------------mN-A-IDDALLQQAHYWMRLTRALDDRGTFLHKQSKIvGGYFSQIGHEALSVAAAMSLGP--R 59 
CBE67815       1 -------------mgvrkP----APDELLNIYYYLKLTRGMEQRVITLYRQGKIvGGVYLGNGEEAIAVGSASALER--D 61 
WP_025412592  20 SPESrvp-gpeSrp---sD-A-LTRDQKLDLYYWMRLTRTLEERLVALYRQTKVvGGLFRSLGQEADAVGSTFALER--R 91 
WP_099326318   1 ------------------M-E-IKKDDLLQMYYYLKLTRRLEDRVTSLYHQGKImGGAWTSNGTEAVSVGYGYALEK--D 58 
WP_114984493   2 QAyk-------------yF-S-LGDDTAVQHYRNLILPRRIEEKMLRLLRQNRI-SKWFSGMGQEAIPVGVASALQA--E 63 
WP_014099938   2 SPEVves-lpaTvp---hP-S-LSREQQHEIYHYLKLTRLLEERLVNLYRQTKVvGGLYRSLGQEATAVGSAYALDKshN 75 
WP_014431464   1 ----------------mmtsylLTNQQRLELFYWMLLTRVFDETMVNLWKQGRGiGGTFSQRGHEAISVGAAYALGP--D 62 
ARU40273      15 GTDSp-----vSr-----PsDrLTHDDYRELLLQLYLARYFDVRLIKEKKRGRLrGTLYSSHNQEAILVGSLYGLEP--M 82 
1UM9_A        88 fDWVFPYYRDHGLALAL------------GIPLKELLGQMLATKADPNKGRQMPEH-PGSKALNFFTVASPIASHVPPAA 154
WP_084179654 115 -DWISPIHRDMSAFFLKdakfrwrdanrmGLTIEQVCSQVWGKVTSPGRARDNWSH-IGSREKRIIHSTSMLAGTIPVAA 192
WP_015942447  60 -DIIAPMHRDLGAYLVR------------GLTPRRILAQWLGRETGVTRGRDANLHgMGDLSLGIIGFISHLPASTGVIT 126
CBE67815      62 -DVIAPTHRDLGANLVK------------GITPKEYMTHYLARQTGLTRGRDGNVH-FGDITRGIIGFISPMADLLPVAA 127
WP_025412592  92 -DIMSPLIRNLGSMLVK------------GATPVEVLKQYMAKGDSPTRGRELNIH-FGDLDRGFIGQISPLGDMVPVMA 157
WP_099326318  59 -DIAAPYFRDMGVFLIR------------GISAKRIIAQYFGKKTGVTGGKEGNVH-IGDMKYGVVGFPSHLADNYPVGA 124
WP_114984493  64 -DVIMTMHRNLGVFTTR------------GVPLYNLFCQLLGKKDGFTNGRDRSFH-FGLPDYNTCGMISHLAAMLPVAD 129
WP_014099938  76 -DMIAPLIRDLGAMLVI------------GATPRELLLQYMAKRDSPTRGRDLQIH-FADLRRGFIGPISHLGDMLPVMC 141
WP_014431464  63 -DVIAPMHRDLGAYLLR------------GLTPTRVFGNLLGRANGVSGGRDANLHgMGDLRHRIIGFISHLPHSLPVAL 129
ARU40273      83 -DWISPIHRDMPAFFLKdfkagwenpdrmGMSIEEVCSQVWGKATSPGRARDNWSH-IGSKAKRIIHSTSMLAGTIPAAT 160
1UM9_A       155 GAAISMKLLRTGQVAVCTFGDGATSEGDWYAGINFAAVQGAPAVFIAENNFYAISVDYRHQTHSPTIADKAHAFGIPGYL 234
WP_084179654 193 GVVYADRLNGGDAVCLTYNGEGSTAQGIFHEAINYAAVHKLPVVTIIENNQWAYGTPTQLEYSQRDFARRADGFGIPGIV 272
WP_015942447 127 GVAHGIKLKGEPRVAMCFFGDGSASQGLAHEAMNWASVFKLPMVIICENNRYAYSTPLSRQMAIEHIAQRAAGYNMPGVI 206
CBE67815     128 GVALTFKLRRERRVVAAFFGDGASSRGDFHEALNLAAVLKLPVVFICHNNQYAYSTPLSRQMAIEHVADRAKAYGMPGII 207
WP_025412592 158 GVTLTFKQRGEDRVGLVYVGDGATSTGAFHEGINFAAVQRCPLVVVVENNGYAYSTPTAKQTLARQFVDKAPGYGIAAEQ 237
WP_099326318 125 GVALAFKIRGEKKVVAACTGDGGTSRGDFHEGMNFASVRKLPIVFFCNNNQYAYSTPLRLQMNIKDVAERAAAYGMPGKI 204
WP_114984493 130 GFALAAKLKQEQRVALAFCGEGSTSEGDFHEAMNLAAVWDLPVLFMIENNGYALSTPTREQYRCARIADKAAGYGMESRV 209
WP_014099938 142 GIALGSRLRRESRVCLVYMGDGASSTGAFAEGMNFAAVQRLPVVVIVENNGYAYSTPTSRQMAVERIVDKAVGFGVRGER 221
WP_014431464 130 GAAMSFVYRNEPCVALTFTGDGASSAGLFHETLNMASLWNAPLIVIVENNQYAYSTPLHQQMKVPDIARRAEIYGMAGVT 209
ARU40273     161 GVTLADRLNGLNTIAMTFNGEGSTAQGVFHEAINFAAVEKLPVVTIIENNQWAYGTPTHYEYALEDFARRADGYGIPGFV 240
1UM9_A       235 VDGMDVLASYYVVKEAVERARRGEGPSLVELRVYRYGPHSSADd--dSRYRPKEEVAFWRKK-DPIPRFRRFLEARGLWN 311
WP_084179654 273 ADGQDVFDVYDKVMEAVEYARSGQGPSIVECKTFRAYGHGDHDddraARYRPPEEIEKGRSR-DPIAVCRRQLLELGHLS 351
WP_015942447 207 VDGNDFVAVYQAATEAVERARAGGGPTFIECKTMRMRGHAIHDn---MAYVPKDLLAAWEAR-DPIARIEAELRARGLLD 282
CBE67815     208 VDGNDVLAVHDAVAEAIARARAGDGPSLVEGKTMRMRGHAEHDd---ASYVPPGLLEEWRKR-DPIDRFAACLRDRKILD 283
WP_025412592 238 ADGNDVLAVYDVTKRAVDRARRGEGVTLVELMTYRRKGHAEHDn---QSYVPAGEIERWAAEnDPVDRYLNVLTSELGFA 314
WP_099326318 205 VDGNNVVEVYMAAKEAYEVARNGGGPTFIECKTMRMHGHSEHDs---AKYVPRELLEEWKKK-DPITNMERYLTEKNIAG 280
WP_114984493 210 IDGNHLPDVIEAVAEARAFALAEQKPVLIEALTFRMRGHEEASg---TAYIPKELFETWAKK-DPILQFEKLLKEQGLMD 285
WP_014099938 222 VDGNDVLAVYDVTRRAVEHARAGGGVTLIEAVTFRMKGHAEHDd---QRYVPKELLAAWAAK-DPLQRYERYLLETGLAT 297
WP_014431464 210 VDGNDVEAVYTVVQEAVTRARRGGGPTLIEAKTMRMLGHAIHDg---AEYVPRELLEQWEAR-DPVRCYRQKLLDEGVAD 285
ARU40273     241 ADGQDVIDVFDKVMMAVEHARSGRGPSIVECKTFRAYGHGDHDddraDRYRPEEEVTEGRKR-DPLHVLKERMISMGILT 319
1UM9_A       312 EEWEEDVREEIRAELE---------------RGLKEAEEAGPV--PPeWMFEDVFA-EK 352
WP_084179654 352 EEEAAKYHAEGKNAAEasnddfppevveflnEGIKFAIAADVP--EAeEAALWVFK-ES 407
WP_015942447 283 DAKLAALLTKIEAELD---------------EAQAFAEASPYP--DPaTLTDGVYA--- 321
CBE67815     284 DASAKTIDDRIAKEIE---------------EAVLFAESSPLP--DAkELLEGVYA-A- 323
WP_025412592 315 SDELTAVDERVRREVD---------------EATEIAETSGFP--EPlDALVGIYA-EP 355
WP_099326318 281 KEELDGIDSRVKKEID---------------EAEAFAEESPYP--DPaDGLKGVYA-TS 321
WP_114984493 286 DADFERLKAEADAFFL---------------DDLNRALEAPEPvfDEeSETAAIFS-It 328
WP_014099938 298 PDELEAITQRISRQLD---------------DDVAFAEANPMP--EPaSALLDVYA-S- 337
WP_014431464 286 ETELAEIARRVEVEIA---------------DALAQAEASPLP--DPaTVEQGVYAgE- 326
ARU40273     320 QEEADKHPAENKGAGEvtdadfppkvveyltKGVQFAIKAPLP--DEtEGAMWVFK-ED 375
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