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?cl40676: Epimerase_2 Superfamily (this model, PSSM-Id:424307 is obsolete)
UDP-N-acetylglucosamine 2-epimerase This family consists of UDP-N-acetylglucosamine 2-epimerases EC:5.1.3.14 this enzyme catalyzes the production of UDP-ManNAc from UDP-GlcNAc. Note that some of the enzymes is this family are bifunctional, in these instances Pfam matches only the N-terminal half of the protein suggesting that the additional C-terminal part (when compared to mono-functional members of this family) is responsible for the UPD-N-acetylmannosamine kinase activity of these enzymes. This hypothesis is further supported by the assumption that the C-terminal part of rat Gne is the kinase domain.
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Jiyao W et al.(2023). "The conserved domain database in 2023.",