1B26


Conserved Protein Domain Family
GdhA

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COG0334: GdhA (this model, PSSM-Id:223411 is obsolete and has been replaced by 440103)
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Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]
linked to 3D-structure
Statistics
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PSSM-Id: 223411
Aligned: 66 rows
Threshold Bit Score: 286.828
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1B26_A    21 MDLESDLAEVLRRPKRVLIVEFPVRMDDGHVEVFTGYRVQHNVARGPAKGGIRYHPDVTLDEVK----ALAFWMTWKTAV 96  Thermotoga maritima
15612781   1 MLTKTPTVTSTLDIFTEMAEHEQVLFCHDPSSGLRAIIAIHDTTLGPALGGCRMYPYQTTEDALrdvlRLSKGMTQKCAA 80  Bacillus halodurans
15615328   1 ---------MELFSYMETYDYEQVVVCQDKTSGLKAIIAIHDTTLGPALGGTRMWMYENENAAFedalRLAKGMTYKNAA 71  Bacillus halodurans
1706415    1 ---------MELFKYMEKYDYEQLVFCQDEQSGLKAIIAIHDTTLGPALGGTRMWTYENEEAAIedalRLARGMTYKNAA 71  Bacillus subtilis
16126321   1 ---------MTLFDSPDFEGHEGVHAFFDEKTGLKSIIAVHSTARGPAAGGCRMWDYSSADAALtdalRLSRGMSYKNAM 71  Caulobacter crescen...
15618828   1 ------MKYSLNFKEIKIDDYERVIEVTCSKVRLHAIIAIHQTAVGPALGGVRASLYSSFEDACtdalRLARGMTYKAII 74  Chlamydophila pneum...
15605506   1 ------MKYSLQIEDLHIEGYEQVLKVTCESVQLVAVIAIHQTKVGPALGGIRAFPYLQFEDGLqdalRLSKAMTYKALL 74  Chlamydia trachomatis
15805195   2 PSAAPGGTRMLILDEMQARGHESLKLLHHAPSGLRGVLAVHSRVLGPAIAGVRLREEDEELAVRga-lALSESLTLKAAL 80  Deinococcus radiodu...
15598614   1 -----------MFDMMDAARLEGLHLAQDPATGLKAIIAIHSTRLGPALGGCRYLPYPNDEAAIgdaiRLAQGMSYKAAL 69  Pseudomonas aerugin...
17227922   1 ---------MQLFETVREMGHEQVLYCHGKNPDIRAIIAIHDTTLGPAMGATRLYPYINEEAALrdalRLSRGMTYKAAC 71  Nostoc sp. PCC 7120
1B26_A    97 MNLPFGGGKGGVRVDPKK--LSRNELERLSRRFFSEIQVIIGpyNDIPAPDVNTNADVIAWYMDTYSMNVGHTVLgivtg 174 Thermotoga maritima
15612781  81 ADVDFGGGKAVIIGDPA-----KDKSANLFRAFGQFVESLNG--RFYTGTDMGTTMEDFVHALKETNGIVGIPKE----- 148 Bacillus halodurans
15615328  72 AGLNLGGGKTVIIGDPR-----KDKNEEMFRAFGRYIQGLNG--RYITAEDVGTTVDDMDIIHQETDYVTGISPA----- 139 Bacillus halodurans
1706415   72 AGLNLGGGKTVIIGDPR-----KDKNEEMFRAFGRYIQGLNG--RYITAEDVGTTVEDMDIIHDETDYVTGISPA----- 139 Bacillus subtilis
16126321  72 ADLDFGGGKAVIIGDSR-----SQKTPELFEAFGRAVDSLGG--QYWTAEDVGVSPSDLESTRKTTRFVAGLEGH----- 139 Caulobacter crescen...
15618828  75 SNTGTGGGKSVIILPQDA----PSLTEDMLRAFGQAVNALEG--TYICAEDLGVSINDISIVAEETPYVCG---I----- 140 Chlamydophila pneum...
15605506  75 SSTETGGGKSVIFLPKGM----TSPTEGMLRAFGQAVNSLQG--KYIAAEDVGVSVQDVMIIREETPYVCG---L----- 140 Chlamydia trachomatis
15805195  81 AGLNYGGG-ACVLLMPEAgvEDPHAREALFRALGRQVQHMNT--RVVLTEDIGVTPADIAFVAQETPATL---------- 147 Deinococcus radiodu...
15598614  70 AGLEQGGGKAVIIRPPH-----LDNRGALFEAFGRFIESLGG--RYITAVDSGTSSADMDCIAQQTRHVT----S----- 133 Pseudomonas aerugin...
17227922  72 ANIPAGGGKAVIIANP------EDKTDEMLRAYGRFVESLKG--RFITGQDVNITPQDVRTIKQETNYVVGVE------- 136 Nostoc sp. PCC 7120
1B26_A   175 kpveLGGSKGREEATGRGVKVCAG-LAMDVLGID-PKKATVAVQGFGNVGQFAALLISQElGSKVVAVSDSRGgiyNPeg 252 Thermotoga maritima
15612781 149 ----YGGSGDSSVPTAKGVINSLKaISQVVLKDKqFSGRTYAIQGLGKVGFKVAEELLKE-GNDLYVSDLQES---LPl- 219 Bacillus halodurans
15615328 140 ----FGSSGNPSPVTAFGVFVGMKaAAREAFGTDdLAGKTVAVQGVGNVSYNLCKHLHEA-GADLIVTDIHKe------- 207 Bacillus halodurans
1706415  140 ----FGSSGNPSPVTAYGVYRGMKaAAKAAFGTDsLEGKTIAVQGVGNVAYNLCRHLHEE-GANLIVTDINKq------- 207 Bacillus subtilis
16126321 140 ----AAASGDPSPVTAEGVFRGVRlCVERALN-RdLKGVRVAIQGVGHVGAYLAEKLHAA-GAELIIADVNQv------- 206 Caulobacter crescen...
15618828 141 ----ADVSGDPSIYTAHGGFLCIKeTAKYLWGSSsLRGKKIAIQGIGSVGRRLLQSLFFE-GAELYVADVLEr------- 208 Chlamydophila pneum...
15605506 141 ----VTVSGDPSIYTAHGVFLCIQeTADYLCKTd-IRGKRVAVQGLGAVGRKLVHELFFA-GAELIVYDTRKd------- 207 Chlamydia trachomatis
15805195 148 -----GMNTDTSSVTGYGVYRGMKaAAKHALGAEsLRGVRVAILGVGAVGRTLAQHLSRE-GAKLTVADFRPD------- 214 Deinococcus radiodu...
15598614 134 ----TTQAGDPSPHTALGVFAGIRaSAQARLGSDdLEGLRVAVQGLGHVGYALAEQLAAV-GAELLVCDLDPg------- 201 Pseudomonas aerugin...
17227922 137 -----EKSGGPAPITALGVFLGIKaAVEFRWQTKnIEGMTVAVQGLGNVGQNLCRHLHEN-GIKLIVADFSSe------- 203 Nostoc sp. PCC 7120
1B26_A   253 fdveelirykkEHGTVVTYPK--GERITNEELLELDVDILVPAALEGAIHAGNAERIKAKAVVEGANGPTT-PEADEILS 329 Thermotoga maritima
15612781 220 -----------RLQQLGQRLGrhVEILHGDEIYEAAADVFVPCAQGAILNDATIARLKVKAIAGAANNQLE-AERHGQML 287 Bacillus halodurans
15615328 208 -----------SVERAIRDFG--AKAVDVGDIYGVDCDIFAPCALGAIINDDTIPQLKAKVIAGAANNQLK-EQVHGDMI 273 Bacillus halodurans
1706415  208 -----------SVQRAVEDFG--ARAVDPDDIYSQDCDIYAPCALGATINDDTIKQLKAKVIAGAANNQLK-ETRHGDQI 273 Bacillus subtilis
16126321 207 -----------ALAEVAAKTG--ATIVPTDAIFDVEADVFAPCALGGAISNATLPRLKVKVIAGGANNQLA-DAMIGQTV 272 Caulobacter crescen...
15618828 209 -----------AVQDAARLYG--ATIVPTEEIHALECDIFSPCARGNVIRKDNLADLNCKAIVGVANNQLE-DSSAGMML 274 Chlamydophila pneum...
15605506 208 -----------LLDEVVTLYG--AQVD--ENIISADCDILCPCALGGIINSMSIDQLRCRAIVGATNNQLE-NPAIGREL 271 Chlamydia trachomatis
15805195 215 -----------RAQALAEELGh-VTVVPVGEIFDVPCDVFAPCGFGHSVQSADVPRLQCRLIAGGEHHPLT-RRGEEAVK 281 Deinococcus radiodu...
15598614 202 -----------RVQLAVEQLG--AHPLAPEALLSTPCDILAPCGLGGVLTSQSVSQLRCAAVAGAANNQLE-RPEVADEL 267 Pseudomonas aerugin...
17227922 204 -----------KTAEIKHLFG--ATVVEPDEIYSQNVDIFSPCAMGGIINSQTIPQLQAKIIAGAANNQLDnERLHGQRL 270 Nostoc sp. PCC 7120
1B26_A   330 -RRGILVVPDILANAGGVTVSYFEWVQDLQSFFWDLDQVRNALEKMMKGAFNDVMKVKEKYNvDMRTAAYILAIDRVAYA 408 Thermotoga maritima
15612781 288 hDQGIWFAPDYIVNSGGLIQVADELY----G--SNEKRVLSKTNAIYDTILEIFHQAERHHI-TTLQAANQLCERRIRER 360 Bacillus halodurans
15615328 274 hEMGIVYAPDYVINAGGVINVADELS----G--YNRERALKKVEGIYDNLAKVFEIAKRDGI-PTYKAADRMAEERIERM 346 Bacillus halodurans
1706415  274 hEMGIVYAPDYVINAGGVINVADELY----G--YNAERALKKVEGIYGNIERVLEISQRDGI-PAYLAADRLAEERIERM 346 Bacillus subtilis
16126321 273 fDRGILYAPDYVINGGGIINVAAEIRALEAGGAFDGGWVASKLDRLAQTLAEVIDQSISEKR-PANLVADEIARARIAAA 351 Caulobacter crescen...
15618828 275 hERGILYGPDYLVNAGGLLNVAAAIEG----RVYAPKEVLLKVEELPIVLSKLYNQSKTTGK-DLVALSDSFVEDKLLAY 349 Chlamydophila pneum...
15605506 272 vARGILYAPDYLANAGGLLNVAGSVG-----RAYSPKEVLSKVEGLPKILRKLYEQGAKENR-DTGTLADAIVEERLAVY 345 Chlamydia trachomatis
15805195 282 -EAGIMYVPDFAINSAGLIAAATGVN---------MDQAGERVYQTVSRIMSVATQYGKP----PHVVARKMAERRIDLI 347 Deinococcus radiodu...
15598614 268 eARGILYAPDYVINSGGLIYVALKHR----G--ADPHSITAHLARIPARLTEIYAHAQADHQ-SPARIADRLAERILYGP 340 Pseudomonas aerugin...
17227922 271 vEKDILYCPDYVINAGGIINVYNEMI----G--YEEDKAFKQVNNIYDTLLAIFNIAQQQSI-TTNDASKRLADERIMKA 343 Nostoc sp. PCC 7120
1B26_A   409 TK 410 Thermotoga maritima
15612781 361 AR 362 Bacillus halodurans
15615328 347 RR 348 Bacillus halodurans
1706415  347 RR 348 Bacillus subtilis
16126321 352 RG 353 Caulobacter crescentus CB15
15618828 350 TS 351 Chlamydophila pneumoniae CWL029
15605506 346 A- 346 Chlamydia trachomatis
15805195 348 GS 349 Deinococcus radiodurans
15598614 341 Q- 341 Pseudomonas aeruginosa PA01
17227922 344 RI 345 Nostoc sp. PCC 7120
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