Conserved Protein Domain Family
TrkA

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COG0569: TrkA (this model, PSSM-Id:223643 is obsolete and has been replaced by 440335)
Trk K+ transport system, NAD-binding component [Inorganic ion transport and metabolism]
Statistics
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PSSM-Id: 223643
Aligned: 70 rows
Threshold Bit Score: 96.5669
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
15794703   1 MKILILGNGQVGSTVAQNLAAIPNNDVTVIDIDEKALQETGSRLDVQTVFGNGASPFTLERAGAEDADLLLALSRSDETN 80  Neisseria meningiti...
20091051   1 MRLIIIGASSLGMHLTHTMIRQGNEVVLIEKDEEVARE-LAEELDCTVINAEGTHPDILEKAGMDCTDAVVACTNHDQDN 79  Methanosarcina acet...
1351544    4 ADFCIIGLGRFGMQVAQSLKENNFNLLLIDLDDKKTDTASQ--QFDYVICCDASNLTALEELQIDEFAGVIVGVTN-IEA 80  Mycoplasma genitalium
2496387    4 ADFCIIGLGRFGMQVAHSLKENNFTLVLIDNDQHKTNTAAQ--EFDHVVCCDGSNLTALAELQLEEFSAVIVGVTN-IEA 80  Mycoplasma pneumoniae
15842229   1 MRVVVMGCGRVGASVADGLSRIGHEVAIIDRDSAAFNR-LSPQFAGERVLGQGFDRDVLLRAGIQGADAFAAVSSGDNSN 79  Mycobacterium tuber...
15828608   6 KDICIIGIGRFGSAISKQLLKMRKNIMLIDINPSRLKPFED--EISSLYVADATDINALKNLGIQDVETVIVSANN-NIE 82  Mycoplasma pulmonis
15609828   1 MRVVVMGCGRVGASVADGLSRIGHEVAIIDRDSAAFNR-LSPQFAGERVLGQGFDRDVLLRAGIQGADAFAAVSSGDNSN 79  Mycobacterium tuber...
15639133   5 RNFAVVGLGAFGYRVCEVLVQGGGSVVAIDNNAQTVEKVKK--VVSVAILIDTTSETELMKAPLDDVDVAIVAIGTNLQA 82  Treponema pallidum
17229603   1 MYVLIGGAGLVGLTLAQKLVELGHTVAIIDVDHTACRY-AREQVGAMAFEGSAVSTEVLLEAGIRKADALAAVLRNDALN 79  Nostoc sp. PCC 7120
16331317   1 MYILIGGMGSMGSNLAKNLLKMGHTVAAVDTDPLACQY-AREKIGVMAFEGSAVNTSVLLEAGVRKAGAVIAALQEDALN 79  Synechocystis sp. P...
15794703  81 IVACKVAADLFNIPGRIARVRSSEYLEYLSP-KlennengslsifgITETISPEQLVTEQLAGLIDCPGALQVLRFADD- 158 Neisseria meningiti...
20091051  80 ILIGLIAQE-AGVERVIVKTDDTKFMEIAKKlG-------------ISSPINPPHISSTIISDALRGIDTIELSNLIR-- 143 Methanosarcina acet...
1351544   81 SIMICANLRELGQKNIIAKAKNEVHKRVLSTmG-------------IREALIPEKIVGKNLVIRLIHGLENEIINLG--- 144 Mycoplasma genitalium
2496387   81 SIMICANLRELGQKNIIARAKNEVHNRVLRTmG-------------IREALIPEKIVGKNLVIRLIHGMETEIINLG--- 144 Mycoplasma pneumoniae
15842229  80 IISARLARETFGVPRVVARIYDAKRAEVYERlG--------------IPTIATVPWTTDRLLNALMQDTETAKWRDPTg- 144 Mycobacterium tuber...
15828608  83 IVASLLELN---VQYIIARASSKNHSRVLKQiG-------------INVIINPEEEIGTKTALIAGNDKFIRFSEKLQEl 146 Mycoplasma pulmonis
15609828  80 IISARLARETFGVPRVVARIYDAKRAEVYERlG--------------IPTITTVPWTTDRLLNALMQDTETAKWRDPTg- 144 Mycobacterium tuber...
15639133  83 SILTTALLKQRDIPYILARATSPIHETILRKiG-------------ANEILNIEVASATTIAKRLVAPDVTDAIAMTDDi 149 Treponema pallidum
17229603  80 LAMVMLA-KHYGVSHILSRMRHADFAQPLRLaGa-------------NHVISTVELSVSTMVNAIEYPQVESMMHFEQg- 144 Nostoc sp. PCC 7120
16331317  80 LALVTLS-KHYGVPQIVVRMSDGDFAEPYRLaGa-------------THIISTTELALNRVINAIEYPQVDAMMHFEQg- 144 Synechocystis sp. P...
15794703 159 -RVRMVIIQARRGGLLVGRSIADIAqdLPDGADCQICAVYRNN------RLIVPAPQTVIIEGDEILFAAAAENIGAVIP 231 Neisseria meningiti...
20091051 144 --ADVRVISFTTGEQHAGKRISEVQ----FPENTECIGFYRNN------DFILARENPKLEEGDELLIITRSGHIDRIYE 211 Methanosarcina acet...
1351544  145 -NEIIFIRSAVNNKAFFNKRLEEIN--FRQNTDANIISIMRSNk----tVVFPLGPNTEIQPGDIITAVCQQKSLNKYLN 217 Mycoplasma genitalium
2496387  145 -NDILFVRAPVNNKKLFNRTLGEIN--IREHTNANLISIMRNGk----dVVFPLGPNTQIQPGDVITAVCQLSGVNQYLR 217 Mycoplasma pneumoniae
15842229 145 -TVAVAEVVLHEDWVGHRATDLEQAtgARIAFLIRFGTGVLPEpk---tVLQAGDKVYIAAISGRAAEAAAIAALPPSED 220 Mycobacterium tuber...
15828608 147 eDDFVIGSTKLFNTKIEGRTLKSLN---LSKKGINVLLIKRGT------IVEVPTGNTVLKRNDIITIIGKTHLVTAVFE 217 Mycoplasma pulmonis
15609828 145 -TVAVAEVVLHEDWVGHRATDLEQAtgARIAFLIRFGTGVLPEpk---tVLQAGDKVYIAAISGRAAEAAAIAALPPSED 220 Mycobacterium tuber...
15639133 150 sLREIVAPRFFTDKTLEELELREKFnvKIVAVVRTDMDIDPTGnslpkkNIYYPDNAFTFRRADRMFVLGHNRDLRELTQ 229 Treponema pallidum
17229603 145 -QIEVLKISIPNSCYVANRSLAEIAqdSRFPSGS-LIIGYQPHph---eDLVIPNGSTVLESGSTILIATKPGSLHQVID 219 Nostoc sp. PCC 7120
16331317 145 -QIEVLKLSIPPNCTIVGRSVAAIAqdPRFPSGT-LIIGYQANah---eDLKIPNGNTLLEDGSTILAVTKPELVRQLID 219 Synechocystis sp. P...
15794703 232 ELRPKET 238 Neisseria meningitidis Z2491
20091051 212 KLRET-- 216 Methanosarcina acetivorans C2A
1351544  218 YINPKTK 224 Mycoplasma genitalium
2496387  218 YINPNDK 224 Mycoplasma pneumoniae
15842229 221 FESGARR 227 Mycobacterium tuberculosis CDC1551
15828608 218 ILNRQRK 224 Mycoplasma pulmonis
15609828 221 FESGARR 227 Mycobacterium tuberculosis H37Rv
15639133 230 I------ 230 Treponema pallidum
17229603 220 FIEGCK- 225 Nostoc sp. PCC 7120
16331317 220 FMGLCQS 226 Synechocystis sp. PCC 6803
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