1DKR


Conserved Protein Domain Family
PrsA

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COG0462: PrsA (this model, PSSM-Id:223538 is obsolete and has been replaced by 440230)
Phosphoribosylpyrophosphate synthetase [Nucleotide transport and metabolism, Amino acid transport and metabolism]
linked to 3D-structure
Statistics
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PSSM-Id: 223538
Aligned: 76 rows
Threshold Bit Score: 259.442
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1DKR_B     5 YgDKNLKIFSL---NSNPELAKEIADIVGVQLGKCSVTRFSDGEVQINIEESIRGCDCY-IIQSTSDPVNEHIMELLIMV 80  Bacillus subtilis
14601659  14 LeGPEQWVIVGgwgSASAEFSEGLSRNMGLKLVKPVFKLFPDEEEYVRIEGDISGFTGAiVVQSFERPASRSLVYSLLIA 93  Aeropyrum pernix
15669556   3 FfGDKMIVVSG---SQSQNLAFKVAKLLNTKLTRVEYKRFPDNEIYVRIVDEINDDEAV-IINTQKN-QNDAIVETILLC 77  Methanocaldococcus ...
15678808   1 ------MIIGC---SASQKLAASVADLLDEPLCPVETRKFPDGERYIRVKEEVEG-EVTvVQSTGYP-QDENLMELLFMI 69  Methanothermobacter...
14521898   1 -----MFVIG----SGAKHLEEEISR--HGNLINVEIKKFPDGEKYVRVLERGK--EAIvIQSTYHP-QDENLIEALLLG 66  Pyrococcus abyssi
18313735   1 ------MIIAF---QNALDLAAELEG--IGPVAQIEERVFPDGEVLVRLPEARG--EVA-VVARLYPAVNDNLIKLFLTI 66  Pyrobaculum aerophilum
14591667   1 --MNKVFVIG----SGAKHLEEEISK--NAKILKTEIKKFPDGEKYVRILEHGE--EVIvVQSTYRP-QDEHLIETIIIG 69  Pyrococcus horikoshii
17544921   9 TvNGNAQRRVVlalPGNQAAAARLAAPLAAEIGQAEMKRFPDGEFHVRLQTPVCDAEVAiVCTLDRP--DEKVLPLLWLA 86  Ralstonia solanacearum
15897912   1 --MIIMIIIGG---SATNGIDESLSKILSIPLVKVENKIFPDGESYIRVPSSIRDEEVL-LVQTTDYPQDKHLIELFLIA 74  Sulfolobus solfatar...
13541028   1 -----MKIIAL---RSSLKLAARIAEELKTEPVMPDERRFPDGELYLRYDEDLTGHNIFiIGNTHSD-AE--VMEMILTL 69  Thermoplasma volcanium
1DKR_B    81 DALKRASAKTINIVIPYYGYARQDrKA-RSREPITAKLFANLLETAGATRVIALDLHAPQIQGFFDI-PIDHLM--GVPI 156 Bacillus subtilis
14601659  94 DALKEAGVGRIVLMAPYMGYTRQD-RVfLPGEPVSVRAVMRALASSGYNALASIEVHKEYVLDYFDG-STLNIF--PFTY 169 Aeropyrum pernix
15669556  78 DALRDEGVKKITLVAPYLAYARQD-KKfNPGEAISIRALAKIYSN-IVDKLITINPHETHIKDFFTI-PFIYGD--AVPK 152 Methanocaldococcus ...
15678808  70 ENLKDLGADYVRAAIPYFGYGRQE-RRfKSGEAVSAKIVAHLLEAAGADEIVTVNLHENCLSEFFRV-PVRELS--AMPL 145 Methanothermobacter...
14521898  67 DALSEAGFKKLKIVIPYLAYSRQD-RVtKEGEPISVRAIMKMLGLY-YDELYVFDIHNPKTLEHFPG-IAKNIY--PAEA 141 Pyrococcus abyssi
18313735  67 DALNDAGASKIILVIPYMPYARQD-RRfRPGEPISSKTVLKLLAHLNVFGIITVDLHKGYVAEYAPRlVIKNLY--PAEE 143 Pyrobaculum aerophilum
14591667  70 DALKEAGFEKLKLVVPYLAYSRQD-RVtKEGEPISVRAIMKMLGLY-YDELYVFDIHNPKTLDFFPG-KAVNIY--PAKV 144 Pyrococcus horikoshii
17544921  87 IAAHQGGARRVGLVAPYLAYMRQD-AIfQSGEICAARHFAELLTR-YFDWLVAVDPHLHRIPELSDIyGMPVTVaqAAPA 164 Ralstonia solanacearum
15897912  75 ETIRDLGAKKLTAIVPYLAYSRQD-RRfKDGEAISIKTILHILSEVGVNTLVVVEPHKPEELSYFKG-ELKIVH--PYHQ 150 Sulfolobus solfatar...
13541028  70 SAIQDYRTKSVNIIAPYYGYARQH-QRyKNGEPISSQILTEIYSSY-SNSIATVDIHDEKTLSYSKV-KFSDLH--ANDA 144 Thermoplasma volcanium
1DKR_B   157 LGEYFEGKNLED-IVIVSPDHGGVTRARKLADRLKAP-IAIIDKRR--P-RPNVAEVMNIVGNIEGKTAILIDDIIDTAG 231 Bacillus subtilis
14601659 170 MLKETGISCGDN-TIIVAPDKGSLPRVERLARETGCRsYGYLVKER--DrITGEVRLAKSTVDPRGKNAIVVDDIISTGG 246 Aeropyrum pernix
15669556 153 LAEYVKDKLN-D-PIVLAPDKGALEFAKTASKILNAE-YDYLEKTRl---SPTEIQIAPKTLDAKDRDVFIVDDIISTGG 226 Methanocaldococcus ...
15678808 146 IAEHISFL---DdPVIIAPDKGALGHAREVSDILGCE-CDYMEKVRi---SPEVVETRVSDLDVEGKDAVVVDDIISTGG 218 Methanothermobacter...
14521898 142 IANYFKDK-L-GeGLILAPDKGALERAKRVAEVLGLE-YSHFEKERi---SPTEVRMKPVDVDVNGKNVLIVDDIISTGG 215 Pyrococcus abyssi
18313735 144 FAKALGGV---D--VVLSPDFGSVHRAEAVARLLQVP-YTYFEKYRdrS-TGAITLIPRQDVDLRNKRVAIVDDILSTGG 216 Pyrobaculum aerophilum
14591667 145 IAEYFRDK-L-EnGLVLAPDRGALERAKEVANILGLE-YSHFEKERi---SPTEVKMTPVDVNVKGRNVLIVDDIISTGG 218 Pyrococcus horikoshii
17544921 165 MAAWVRAH--VSdPLFIGPDDESRQWVEHVAGLCSAP-WTVLSKTRy--sAWDVAVSAIGSNPRSQHTPVLIDDIISTGR 239 Ralstonia solanacearum
15897912 151 IARKIKEI-IED-PFILAPDRGALDRARKIAEEINAP-YSYIEKERdrT-TGEVRIKEAPNINLKGKDVVIIDDIISTGG 226 Sulfolobus solfatar...
13541028 145 IVRYYKNV---DvDYVVSPDDGGLARVADISAKLGKK-HFFIEKKRi---DDRTVEMKVPNVDVNGKKLLIVDDIISTGG 217 Thermoplasma volcanium
1DKR_B   232 TITLAANALVENGAKEVYACCTHPVLS-GPAVERINNSTIKELVVTNSIKLP-EEkkieRFKQLSVGPLLAEAIIRVHEQ 309 Bacillus subtilis
14601659 247 TIALASQWLLENGANSVFVLAAHYLGIgNAEEKMMKAG-VSRVVTGNTLPRKpSK----IVTYVDLTGLAAGQLTKLVSN 321 Aeropyrum pernix
15669556 227 TMATAVKLLKEQGAKKIIAACVHPVLIgDALNKLYSAG-VEEVVGTDTYLS--------EVSKVSVAEVIVDLL------ 291 Methanocaldococcus ...
15678808 219 TIVNAAGILGKCGASSITVCCVHPVLVeDALLKIFSAG-VERVIATDTLKS--------DVSEISVAPLIADVMKD---- 285 Methanothermobacter...
14521898 216 TMIKAANILRELGAKEIFVVATHGVFAeGAIERVSKA--VNELAVTNTIPT--------EVSKISIVDYIVK--LGEKE- 282 Pyrococcus abyssi
18313735 217 TLVDACKAAKTLGAAEVYAAITHCQLL-KDARERVRSC-VDKIICTDTVLN--------EFAEVRIGRLIRRELEALL-- 284 Pyrobaculum aerophilum
14591667 219 TMIRAAEILKDLGAEKVFVVATHGVFAeGAIERVSKA--VDELAVTNTIPT--------KVSKISIVPEIMRSILEVKS- 287 Pyrococcus horikoshii
17544921 240 TLIAAAHQLHSAGLRRPLCVAVHAVFA-TDAYSELSAV-AADVITCDTIAHP--------SNRIALSEPVAAAISTMFDL 309 Ralstonia solanacearum
15897912 227 TIVQATRLAYSLGAKSVTAAAIHLLLV-GGAKERLREVGVKTLIGTNTINVNd-K----DIITIDVSQSIALSL------ 294 Sulfolobus solfatar...
13541028 218 TIAKSSGLLREKGASKIYVSAVHGLFVnGSENKILQN--ADEIHVTDTVES--------KFSDISVYQEVCNYIRDIDA- 286 Thermoplasma volcanium
1DKR_B   310 Q-SVSYLFS 317 Bacillus subtilis
14601659 322 L-------- 322 Aeropyrum pernix
15669556     ---------     Methanocaldococcus jannaschii
15678808     ---------     Methanothermobacter thermautotrophicus str. Delta H
14521898     ---------     Pyrococcus abyssi
18313735     ---------     Pyrobaculum aerophilum
14591667     ---------     Pyrococcus horikoshii
17544921 310 PlPAAIQRL 318 Ralstonia solanacearum
15897912     ---------     Sulfolobus solfataricus
13541028     ---------     Thermoplasma volcanium
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