225427876   38 LSLYTSMDVNFSAKSQALTLISCTPLYsspspsssfstlrreflgcghnlrppGLRSPKK---CKNIRFRIQSPs-RFYF 113 
115481316    4 TASSFPSPLRLVRHGRLLLLLLNAALQ--------------------------LVWLRWRggdSPEEEEVSHEHdkRIVN 57  
145353124    1 MEVTSTTFISTTRSSKYLTLTSYSPVIlpastlrrdf-------lgcchslrpSPHLRTRagkRNSRRSSIRSP--RLVV 71  
168024390   10 AMASASAAPALQLHSRLCALPSTIPPSllcsr----------------ilhppNSASARCs------------------- 54  
168023641    1 -MASAASPVLQLQRNRLCTLPSSIAPPlpssr----------------flhspNSARCLRgitDS--------------- 48  
255586885    1 ------MELSFSPKSQSLALLSTTNTKfsstkssfirrq---flgcshnlrppGSASPLRgrkSKKIKIREKNQsqSLLI 71  
297798436    1 MEVTSTTFISTTRSSKYLTLTSYSPVIlpastlrrdf------lgcchslrrpSPHLRTRagkRNSRRSSIRSP--RLVV 72  

225427876  114 KASLGSQPVLVVVAVAAvfafsv-vflsysRRRKNSREVSGP----SGFAISQLSRDVMNqfmesailgfGDLHKETSEk 188 
115481316   58 NKALGTSTDLLDDSSYS-------------SRRTHENVFSEP----SVSGRMTVDRTDCQ----------TDVFSGVDT- 109 
145353124   72 RASIDSGLILIVVAVTAfsaiafaycqstfRKRKSSDEVATV----HGGKNSAENRREIH----------GDIHEGNPVe 137 
168024390   55 ------------------------------WSRISSPLLATP-------------REDVRsl------------------ 73  
168023641   49 ------------------------------RTRISSPLLATP-------------REDAA-------------------- 65  
255586885   72 NASFRLDSVLVVVAVSTfsalsfaylhhhfTNKNNKKRKTSKe--dLGDGLSQLGKNIVNnivrspfldvGHLHKVTSTt 149 
297798436   73 RASLDSGLILVIVAVTAfsaiafaycqntfRKRKTSDVVAAStgtiRGGKISTENRRESQhl-------dGDVYEGNPVe 145 

225427876  189 esrat-------------------mdiveeVSHASKDKEAPWQEIALMQEETHVTNTSESSRLDvlss----nakNCVSV 245 
115481316  110 ------------------------------VNNTTQVGSVISTYRSLDTFEGVYGPANTSSIEKvqdi----lpqSRSVS 155 
145353124  138 invgfr------------------kveeesVNLLEEEKAHQIHEVAVMDYDSVSAEDSQFAVAS-----------VTTVA 188 
168024390   74 -----------------------------dLQESSSEHHHLASESSTNGSANGVVNGAAAPRIG---------------- 108 
168023641   66 ------------------------------LEHHAESSTNGAALRASLECVERVSQGGGSELET---------------- 99  
255586885  150 levkskdlvdnarensyvienvlpnetsvlVESTESDKNSYVIENALSNETSVLVESTESDNNSadftvssnvctYVVSK 229 
297798436  146 inggfr------------------kmeeqsVTLLEEEETHQIQEIAVIEYDSFSAEESQFAVAN-----------VSTVA 196 

225427876  246 RETEEAGPSILPPLLSESGLLQPLVFATEMPELQLEERQMETEFGYDLSTPVVQTKSIAASVPDIIALEGVNERKNRGGR 325 
115481316  156 DGQHQSRHFANRRAQLGGLPHQFLSLSKQNEQTKNGQGPPDNKTDSEGANLLGCHQSDQGDYVDFTSLSSFKRINEHPLN 235 
145353124  189 TAHTLIDESFSSSIVNGSVALESATFGVKTPEKQVGNSEDQKGLEHDFSQAVVGIHSIASP----QVVDDTRALEYEYNG 264 
168024390  109 ------------RVPQGGANNLGISHNFPSNGAVNGNVKFQDKQELE-----SGRHLVEEILFTQEFLDTLDYDSYSTAR 171 
168023641  100 -----------LALSHGSSTNGSIPKGGEN---ANGSLPVVERRELDWVAMGSGRQLVEEFLFTQDYLDSLDYDSFDSTG 165 
255586885  230 QSDNASVLLDPVPVIHGSESVLPLEFARELSELTIERSRDETEVDSELTQLLEEKSNDTAS-------------STMNDE 296 
297798436  197 KEHTLIDESLSSSIVNGSVALESATFGVKT---QVENSEDHKCLEHDFSQAVVGIHSIASP----PVVDDTHALEYEYNG 269 

225427876  326 PGEESEIISftgIFRDTIREELYTFYEAKqSVMKP--MPNFNGIKTLASNASlldgngvsfQMRNATSKEAELSAQNSHS 403 
115481316  236 FIPEAHASN---LFEPRKASEFTNSYAGG-SYLRAgrLVPVACLRDGPVSKQ---------KKAMNDHDDAKLIGWSISN 302 
145353124  265 LLQKPLEYS---IFAESKREEIHTFYGSNhSSAKSsrLPSLKAVSPAVTSATnsl----flDHKNNGVIDTQFPGQSSGQ 337 
168024390  172 VLQETATHGgkpTTSPKVVAKLDSVASEKlLRPKLlsTDVVKSVRKKgrvlpasiaevl--------------------- 230 
168023641  166 GVEGAAVVDmngSFAETVTVKVNSVITEErSRKKS-----VKTLQKGsrvlpstilell--------------------- 219 
255586885  297 IGKKDGISSyydITKKSAREDLYKFYEESqSTEKS--PSNLNGLDTVSSHAAplignnissLKVNGVGKEAELLSPQSPQ 374 
297798436  270 LLQKPLEYS---VFAESKREEIHTFYGSNhSSAKSsrLPSLKAVSPTVTSATnsl----llDHKNNGVIDTQFPGHSSGQ 342 

225427876  404 SADYVEGKMSLSCYKEGSSGKRNdlvkgkgfprdkngrlpplsdhrnlsqfplsngmtvkekyhDSEKFSAYNRLLSEGR 483 
115481316  303 LLSKENPENSTSANRAGLRGTKD-----------------------------------------VPDYLRRYNSLLIDGR 341 
145353124  338 ATGDVQEENLVAHSNGGVSHIRKdvkgdwkfpsdgkhvghqid--esmpqfparnfelhnsngrSPETSDAYNRLLRDGR 415 
168024390  231 ---------------------------------------------------------plkpgtsikfyIDLYASLLKAGR 253 
168023641  220 ---------------------------------------------------------plkletnikfyIDVYASMLKAGR 242 
255586885  375 FAETVERKVHLARYERGASRKNEhiggrrgfprekekghviqdehtnlpefpypngvhstnkdhKAEQVHGYNRLLRDGR 454 
297798436  343 ATADVQEEKLVAYGNGGVPHIRKdvkedwkfpndgthvghqtd--esmpqfharnfelhnsngrSPESNDAYNRLLRDGR 420 

225427876  484 LSDCIQLLEDMEKMGLLDMDKVYHAKFFKICRSQKAVTEAFRFAKLIPT-PTLSTFNMLMSVCATSQDSAGAFQVLQLVR 562 
115481316  342 LKDSVDLLESMEQKGLLDMNKIHHASFLNACKKQRAVPEAVRFCKLINN-PKMSTFNMLLSVCANSQDFDGALQVMVLLK 420 
145353124  416 IKDCISLLEDLDQRDLLDMDKIYHASFFKACKKQRAVKEAFRFTKLILN-PTMSTFNMLMSVCASSQDIEGARGVLRLVQ 494 
168024390  254 IKDCLVLLGEINKLDKLSLMKVNHSKFYEVCKTKGTVEDAFTFAKIMRVySTLQHYTMLLSVCCHAKDIDGALRVLALVE 333 
168023641  243 IKDCLKLLGEMDKAGKLARMKVNHSKFYEACKARGSVEDAFAFAKLMREfSTLQHYTMLLSVCCHAKDIDGALRVLALLE 322 
255586885  455 LAECVDLLEDMERRGLLDMSKIYHAKFFKICKIQKAVKEAFRFCKLVPN-PSLSTFNMLMSVCSSSQDSDGAFEVLRLAQ 533 
297798436  421 IKDCISLLEDLDQRDLLDMDKIYHASFFKTCKKQRAVKEAFRFTKLILN-PTMSTFNMLMSVCASSQDIEGARGVLRLVQ 499 

225427876  563 EAGLKADCKLYTTLISTCAKSGKVDAMFEVFHEMVNAEVEPNVHTYGALIDGCGRAGQVAKAFGAYGIMRSKKVEPDRVV 642 
115481316  421 EAGLKPDCKLYTTLISTCAKCGKVDAMFEVFHEMVSAGIEPNVNTYSALIDGCAKAGQVAKAFGAYGIMSSKKVKPDRVV 500 
145353124  495 ESGMTADCKLYTTLISSCAKSGKVDAMFEVFHQMSNSGVEANLHTFGALIDGCARAGQVAKAFGAYGILRSKNVKPDRVV 574 
168024390  334 SRGFKADCVFYTTLISACSKAGKVDLLFQILHEMDVAGVEANVHTFGAMIDGCARAGQLPKAFGAYGIMISKDVKPDRVI 413 
168023641  323 SRGLKADCMFYTSLISACAKAGKVDLLFQIFHEMEVAGIEANVHTFGAMIDGCARAGQLPKAFGAYGIMISKNVKPDRVI 402 
255586885  534 GAGLKADCKLYTTLISTCAKSGKVDAMFEVFHEMVNAGVEPNVHTYGSLIDGCAKAGQMAKAFGAYGILRSKNVKPDRVV 613 
297798436  500 ESGMTADCKLYTTLISSCAKSGKVDAMFEVFHQMSNSGVEANLHTFGALIDGCARAGQVAKAFGAYGILRSKNVKPDRVV 579 

225427876  643 FNALITACGQSGAVDRAFDVLAEMRAE------TQPIDPDHITVGALIKACTNAGQVDRAREVYKMIDQYNIKGTPEVYT 716 
115481316  501 FNALISACGESGAVARAFDVLSEMTAEaseskgSKPILPDHVTVGALMKTCIQAGQADRAREVYKMLQEYNIKGTPEVYT 580 
145353124  575 FNALISACGQSGAVDRAFDVLAEMKAE------THPIDPDHISIGALMKACCNAGQVERAKEVYQMIHKYGIRGTPEVYT 648 
168024390  414 FNTLINACSRVGAVQRAFDVLADMKSE------ATPVKPDHVTYGALISACAKGGEVGRALEVYQSMRENDVKGFLACYT 487 
168023641  403 FNTLINACTRAGAVQRAFDVLTDMKAE------ATPIKPDHVTYGALISACARAGEVDRALEVYQNMRESNVKGSPACYT 476 
255586885  614 FNALITACGQSGAVDRAFDVLAEMGAE------THPIDPDHITVGALMKACAKAGQVDRAKEVYNMLHKYNIKGTPEVYT 687 
297798436  580 FNALISACGQSGAVDRAFDVLAEMKAE------THPIDPDHITIGALMKACCNAGQVERAKEVYQMIHKYGIRGTPEVYT 653 

225427876  717 IAVSSHSQIGDWEFAYSVYTDMTRKGVVPDEMFLSALIDVAGHAGKLDAAFEVIQEARIQGIPLGIVSYSSLMGACSNAK 796 
115481316  581 IALRSCSLTGDLGFALKIYEDMNKIGVQPDEMFLSALVDVAGHARRADAAFEIMKDARAKGYQVGTIAYSSLMGACCNAK 660 
145353124  649 IAVNSCSKSGDWDFACSIYKDMKEKDVTPDEVFFSALIDVAGHAKMLDEAFGILQDAKSQGIRLGTISYSSLMGACCNAK 728 
168024390  488 AAVHACSQKGDLDYALAIYDDLLKDGVKPDEVFFSALVDAAGHSGDVDKAFSILDIMRKSGMKPGAVVYSSLMGVCSNLG 567 
168023641  477 AVVHACSQKGNVDYALLVYDDLKKDGVKPDEVFFSALVDAAGHAQDIEKAFSIIANMKKEGLKPGAVVYSSLMGVCSNLG 556 
255586885  688 IAVNFCSQTGDWEFARSVYDDMTRKGVAPDEMFLSALVDVAGHAGLVDIAFETLQEARTQGTQLGIVPYSSLMGACSNAK 767 
297798436  654 IAVNSCSKSGDWDFACSIYKDMKEKDVTPDEVFFSALIDVAGHAKMLDEAFGILQDAKSQGIRLGTVSYSSLMGACCNAK 733 

225427876  797 NWQKALELYVDIKSMKLNPTVSTMNALITALCEGEQLEKAMEVLSDMKRAGLCPNTITYSILLVASEKKDDIDVGLMILS 876 
115481316  661 DWKKALQLFEEIKSIKLMPTVSMMNALITALCDGDQVLKSFEVLSEMKRLGVCPNMITYSVLFVACERNAEAQLGLDLFE 740 
145353124  729 DWKKALELYEKIKSIKLRPTISTMNALITALCEGNQLPKAMEYLDEIKTLGLKPNTITYSMLMLASERKDDFEVSFKLLS 808 
168024390  568 EWEKGLEVYEGIRSSKLRPTVSTYNALMTALCEAKQFDRALSVLNDLKDAGRTPNQVSYSILLKACEREGKADMALDLYT 647 
168023641  557 NWEKALEVYQDIRSSGLQPTVSTFNALMTALCEANQFTRALSILQDVKNSGIMPNQISYSILLRACEKEKMADMALDLYM 636 
255586885  768 NWQKALELYEDIKAIKLKPTVSTMNALMTALCDGDQLQKALETLSEMKSFGLCPNIVTYSILLVASERKDDLDAGDMLLS 847 
297798436  734 DWKKALELYEKIKLIKLRPTISTMNALITALCEGNQLPKAMEYLDEIKTLGLKPNTITYSMLMLASERKDDFEVSFKLLS 813 

225427876  877 QARKDSVAPNLVMCRCLVGMCLRRFEKACALGEPVLSF-----NSGRPQIDNKWTSSALMVYRETVSAGVIPTMELLSQV 951 
115481316  741 QLKIDSIDLNPTIVGCLTGLCLQMFDNDLSLGNIVVTF-----NLGKPQIENKWTSSAIKVYREAISTGLLPSSDVLSQV 815 
145353124  809 QAKGDGVSPNLIMCRCITSLCKRRFEKACAGGEPVVSF-----KSGRPQIENKWTSMALMVYRETISGGTVPTTEVVSQV 883 
168024390  648 TARAEGIKPNLVICDSIIGLCLQQIQTSVAAPLVSWSIlp-paDNSNISSQQQWVTWALTIYRQTIEAGVLPTVEILSQL 726 
168023641  637 TALSEGIKPNVGICDSITGLCLQQIQSYAAAPQKLWSMlpvpaDSNNLSSTDQWSTWALSVYRQTIEAGTPPKIETLSQL 716 
255586885  848 QAKEDCITPTFLMYKCIIGMCLRRYKKACSLGESILSF-----DSGRPQIKNEWTSRALTVYRETIAAGEKPTMEVVSQV 922 
297798436  814 QAKEDGISPNFIMCRCITSLCKRRFEKACAGGEPVVSF-----KSGRPQIENKWTSMALMVYRETISGGTVPTTEVVSQV 888 

225427876  952 LGCLQFPRDVSLRNRLIENLGVSA--DASRRSNLCSLIDGFGEYDSRAFSLLEEAASLGVVSCVSFKKS-PVIVDTRRLQ 1028
115481316  816 LGCLRFPHDNTLTNTFIENMGISC--DIPHHPNVNSLLEGFGEYDIRAFSILEEAASLGAVESISMKDT-RILVDARKSK 892 
145353124  884 LGCLQLPHDAALRDRLISTLGINI--SSQKQHNIFPLVDGFGEYDPRAFSLLEEATSLGVLPSVSFNKI-PLFFDTTELP 960 
168024390  727 LGCLRKPEASTTPVSIFDDKAAAF--LGQSQPATSTSFDGFGIYDPRALALFEEAAALKIAPMFSYNTLqPIVINAEAMP 804 
168023641  717 LGCLRKLETSTKALTTFDDRTIMAflGQPQVSKSSTPYDGFGIYDPRALALFEEASALKIVPTISSSSVqPIVINAEMMP 796 
255586885  923 LGCLQLPCDASLKGRLVENLGVTA--DPSKFSNLCALVDGFGEYDPRAFSLLEEAASLGTVPCASFKES-PIVMDAKLLQ 999 
297798436  889 LGCLQLPHDAALRDRLISNLSINI--SSQKQHNIFPLVDGFGEYDPRAFSLLEEATSLGVLPSVSFNKI-PLFFDTTELP 965 

225427876 1029 IRIAEVYLLTVLKGLKHRLAAGAKLPSMTILLPTETTQVLAPKGEK-AINLAGRISQAVASMLRRLGLPYQGNESRGKIR 1107
115481316  893 IYTAEVSVLTTLRSLKHRLAAGARLPNVTILLPTEKKQVGLDEREK-TLKLAGRVGQAVGSLLRRLGIKYHGEESHGKMR 971 
145353124  961 KNVAEVYLLTIFKGLKHRLAAGAKIPHINLIISIQEKEIRTPEGEK-TIDLTGRVGQEIGALLRRLDIPYHRKDS--RLR 1037
168024390  805 VFAAEVCLLTVLKSLKHRHAAGARVPSVKIKLHVEKKESYRPKGGLiSINIADRTGQAVAALLRRLRLKAQGSASSGELR 884 
168023641  797 VFAAEVCILTILKGLKHRHAAGARVPGVTIKLHTEKKEFYRTKGGLlSMTMADKTGQAVAALLRRLGLKAQGSESTGELR 876 
255586885 1000 SHIAEVYLLTILKGLKHRLAAGAKLPNITILLPTEMTQIKTLKGEK-TINLAGRISQDVASLLRRLGLPYQGNESYGKIR 1078
297798436  966 KNVAEVYLLTIFKGLKHRLAAGAKIPHINLIISMEEKEIRTPEGEK-TIDLTGRVGQEIGALLRRLDIPYHRKDS--RLR 1042