Conserved Protein Domain Family
Mtu_fam_mce

?
TIGR00996: Mtu_fam_mce 
virulence factor Mce family protein
Members of this paralogous family are found as six tandem homologous proteins in the same orientation per cassette, in four separate cassettes in Mycobacterium tuberculosis. The six members of each cassette represent six subfamilies. One subfamily includes the protein mce (mycobacterial cell entry), a virulence protein required for invasion of non-phagocytic cells. [Cellular processes, Pathogenesis]
Statistics
?
PSSM-Id: 273384
Aligned: 20 rows
Threshold Bit Score: 232.177
Created: 7-Oct-2014
Updated: 25-Oct-2021
Structure
?
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
WP_031726558  14 QLSRASVVIGSLVVVLALAAGIVGVRLyQKLTNNTVVAYFTQANALYVGDKVQIMGLPVGsidKIE--PAG----DKMKV 87  Mycobacterium t...
WP_031736822   9 TSVRVAAALLAGLMVGSAVLTYLSYTAaFTSTDTVTVSSPRAGLVMEKGAKVKYRGIQVG---KVTdiSYSgn-qARLKL 84  Mycobacterium t...
KBV80129      10 LHDAWWTLILFAVIGVAVLVTAVSFTGsLRSTVPVTLTADRSGLVMDSGAKVMMRGVQVGrvaQIGriEWAqn-gASLRL 88  Mycobacterium t...
WP_025985359   9 WLY-VEGVVLLLVGALVLVLVYKQFRGeFTPKTELTMVASRAGLVMEAGSKVTYNGVEIGrvgSISeiERDgrpaAKLVL 87  Mycobacterium t...
WP_024753976   9 IILTASSALLAGCQFGGLNSLPLPGTAgHGEGAYSVTVEMADVATLPQNSPVMVDDVTVGsvaGIVavQRPdg-sFYAAV 87  Mycobacterium t...
WP_031663007   5 LTLVMIAAVVASCGWRGLNSLPLPGTQgNGPGSFAVQAQLPDVNNIQPNSRVRVADVTVGhvt---kiERQg---WHALV 78  Mycobacterium t...
WP_003911253  12 LAVLLAPVVLTSCTWRGIANVPLPVGRgMGPDRMTIYVQMPDTLALNTNSRVRVADVWVGtvr---diSLRn---WIATL 85  Mycobacterium t...
WP_031742783   9 QLILFAIVSVVAIVVLGWYYLRIPSL--VGIGQYTLKADLPASGGLYPTANVTYRGITIGkvtAVE--PTD----QGARV 80  Mycobacterium t...
AIH40356       9 QLSIFAVITVITLSVMAIFYLRLPAT--FGIGTYGVSADFVAGGGLYKNANVTYRGVAVGrveSVG--LNP----NGVTA 80  Mycobacterium t...
WP_024459442  15 RYATVIALVAALVGGVYVLSSTGNKR--------TIVGYFTSAVGLYPGDQVRVLGVPVGeidMIE--PRS----SDVKI 80  Mycobacterium b...
WP_031726558  88 TFHYQNKYKVPANASAVILNPTLVASRNIQLEPPYR--GGpVLADNAVIPVErtQVPTEWDELRDSVSHIIDELGPTPeq 165 Mycobacterium t...
WP_031736822  85 AIDSGEMGFIPSNATVRIAGNTIFGAKSVEFIPPKTpsPK-PLSPNAHVAAS--QVQLEVNTLFQSLIDLLHKIDPLE-- 159 Mycobacterium t...
KBV80129      89 EIDPDQIRYIPANVEAQISATTAFGAKFVDLVMPQNpsRA-RLSAGAVLHSK--NVSTEINTVFENVVDLLNMIDPLK-- 163 Mycobacterium t...
WP_025985359  88 DVNPRYISLIPVNVVADIEAATLFGNKYVALSAPKIpqQQ-RISSHDVIDVG--SVTTEFNTLFETITSIAEKVDPIE-- 162 Mycobacterium t...
WP_024753976  88 KLDLDKNVLLPANAVAKVSQTSLLGSLHVELAPPTDrpPTgRLVDGSRITEAntDRFPTTEEVFSALGVVVNKGNVGA-- 165 Mycobacterium t...
WP_031663007  79 TMRLDGDVDLPANATAKIGTTSLLGSYHIELAPPKGeaRQgKLRDGSLIALShgSAYPSTEQTLAALSLVLNGGGLGQ-- 156 Mycobacterium t...
WP_003911253  86 TLELEPTVRLPANATAKIGQTSLLGTQHVELAAPPIpsPQ-PLKSGDTIGLKnsSAYPTVERTLASVALILTGGGIVN-- 162 Mycobacterium t...
WP_031742783  81 TMSIASNYKIPVDASANVHSVSAVGEQYIDLVS-TGa-PGkYFSSGQTITk--gTVPSEIGPALDNSNRGLAALPTEK-- 154 Mycobacterium t...
AIH40356      81 HMRLNSGTAIPSNVTATVRSVSAIGEQYIDLVPPENp-SStKLRNGFRIQRQntRIGQDVADLLRQAETLLGSLGDTR-- 157 Mycobacterium t...
WP_024459442  81 TMSVSKDVKVPVDVQAVIMSPNLVAARFIQLTPVYT--GGaVLPDNGRIDLDrtAVPVEWDEVKEGLTRLAADLSPAAge 158 Mycobacterium b...
WP_031726558 166 pkgpFGEVIEAFADGLAGKGKQINTTLNSLSQALNALNEGRGDFFAVVRSLALFVNALHQDDQQFVALNKNLAEFTDRLT 245 Mycobacterium t...
WP_031736822 160 ----TNATLSALSEGLRGHGDDLGALLSGLNTLTRQANPKLPALQEDFRKAAVVANVYADAAGDLNTVFDNLPTINKTIV 235 Mycobacterium t...
KBV80129     164 ----LNAVLTAVADAVRGQGERIGQATTDLNEVLEALNARGDTIGGNWRSLKNFTDTYDAAAQDILTILNAASTTSATVV 239 Mycobacterium t...
WP_025985359 163 ----LNATLSAVAQALDGLGGKFGESIVNGNQILAQLNPRLPQLGYDVRRLADLGEVYVDASPDLWSFLQNALTTARTLT 238 Mycobacterium t...
WP_024753976 166 ----LEEIIDETHQAVAGRQAQFVNLVPRLAELTAGLNRQVHDIIDALDGLNRVSAILARDKDNLGRALDTLPDAVRVLN 241 Mycobacterium t...
WP_031663007 157 ----VQDITEALSTAFAGREHDLRGLIGQLDTFTAYLNNQSGDIIAATDSLNRLVGKFADQQPVFDRALATIPDALAVLA 232 Mycobacterium t...
WP_003911253 163 ----LDVIQTEILNILDGHAGQIREFLERLATFTAELNNQRGDLTRAIDSTNQLLTIIANRNDTLDRVLTDVPPLIEHFA 238 Mycobacterium t...
WP_031742783 155 ----IGLLLDETAQAVGGLGPALQRLVDSTQAIVGDFKTNIGDVNDIIENSGPILDSQVNTGDQIERWARKLNNLAAQTA 230 Mycobacterium t...
AIH40356     158 ----LRELLHEAFIATNGAGPELARLIESARLLVDEANANYPQVSQLIDQAGPFLQAQIRAGGDIKSLADGLARFTWQLR 233 Mycobacterium t...
WP_024459442 159 lqgpLGAAINQAADTLDGNGDSLHNALRELAQVAGRLGDSRGDIFGTVKNLQVLVDALSESDEQIVQFAGHVASVSQVLA 238 Mycobacterium b...
WP_031726558 246 HSDADLSNAIQQFDSLLAVARPFFAKNREVLTHDVNNLATVTTTLLQPdpLDGLETVLHIFPTLAAN 312 Mycobacterium tuberculosis
WP_031736822 236 DQKDNLNDTLLATIGLSNNAYETLAPAEQNFIDAINRLRAPLKVTSDY--SPVFGCLFKGIARGVKE 300 Mycobacterium tuberculosis
KBV80129     240 NHSTQLDALLLNAIGLSNAGTNLLGSSRDNLVGAADILAPTTSLLFKY--NPEYTCFLQGAKWYLDN 304 Mycobacterium tuberculosis T...
WP_025985359 239 SQQRDLDAALLAATGAGNTGEDVFARGGPYLARAAADLVPTATLLDTY--SPELFCMIRNFHDAAPK 303 Mycobacterium tuberculosis
WP_024753976 242 QNRDHIVDAFAALKRLTMVTSHVLAETKVDFGEDLKDLYSIVKALNDD--RKDFVTSLQLLLTFPFP 306 Mycobacterium tuberculosis
WP_031663007 233 DERDTLVEAAEQLSKFSALTVDSVNKTTANLVTELRQLGPVLESLANS--GPALTRSLSLLATFPFP 297 Mycobacterium tuberculosis
WP_003911253 239 DTGQLFADATESLGRFSEVANRALAATRPNLHQTLQSLQRPLRQLERA--SPYVVGALKLGLTAPFN 303 Mycobacterium tuberculosis c...
WP_031742783 231 TRDQNVRSILSQAAPTADEVNAVFSGVRDSLPQTLANLEVVFDMLKRY--HAGVEQLLVFLPQGAAI 295 Mycobacterium tuberculosis
AIH40356     234 AADPRLRDTLADAPDAIDEANTAFSGIRPSFPALAASLANLGRVGVIY--HKSIEQLLVVFPALFAA 298 Mycobacterium tuberculosis
WP_024459442 239 DSSANLDQTLGTLNQALSDIRGFLRENNSTLIETVNQLNDFAQTLSDQ--SENIEQVLHVAGPGITN 303 Mycobacterium bovis
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap