Conserved Protein Domain Family
DUF4238
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pfam14022: DUF4238 (this model, PSSM-Id:404838 is obsolete and has been replaced by 464067)
Protein of unknown function (DUF4238)
This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 274 and 374 amino acids in length.
Links
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Statistics
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PSSM-Id: 404838
Aligned: 58 rows
Threshold Bit Score: 99.0749
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Download Cn3D
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
XP_013957553     4 QHFIPQ-FILRNYSYPlkcpnaekkgkkkckckhekgkypgDLVTNCVDLTLSPFRLe--TYSVKRIFGAPNMYN----- 75  Trichoderma v...
WP_015328605     7 HHKIPH-FYLDQWKDPcs----------------------eKSTIWIFNKDSLDCS----PRLTKDAFVEGHYFTeq--- 56  blue-green algae
jgi:Emtol_0641  12 HHLVPQkGYLEKFTNR-------------------------NKQIFKCKLDTKLPQKf-kGFATAAICYDKDYYKfd--- 62  Emticicia oli...
CCH02007         7 QHYLPQ-VYLKQFVNS-------------------------QHKLYTLVIKAHARAPqakEASPKSTGCAPDYFTlt--- 57  Fibrella aest...
jgi:Solca_0859   4 HHYVPQ-CYLKSFNNI-------------------------QKNVFTLSKQGKKII----SRSCAQICYTPNLYTlt--- 50  Solitalea can...
jgi:Cpin_4218    8 HHYVPE-GYLKVFTNF-------------------------QNSLWQFKKDYRKIS----LKTPAQVCYEVDANRfk--- 54  Chitinophaga ...
WP_012791141     9 HHYVPV-CYLKQFANL-------------------------GGNLLKKRLDYDKIA----ITTPSKICYEIDGNRfn--- 55  Chitinophaga ...
WP_014021326     7 HHFVPK-FLLKPWTYD-------------------------EKNLWLYLKSNIEVSPr--SASIADVGHEKNLYTsr--- 55  Cyclobacteriu...
jgi:Ftrac_0420  10 NHYVPV-WYLKHFTNK-------------------------EGLIYVFDKQARYRSKeilQKTPNQICYEYNRYLmk--- 60  Marivirga tra...
Q24NM4           7 HHLIPK-TYLKSWCFS-------------------------GMSVYSFNKAELSKPV---VKNLKNNFGENNYHSikagm 57  Desulfitobact...

XP_013957553    76 ------Dpa------------------------------------------------------kATSDEQRRIE-CMFSK 94  Trichoderma v...
WP_015328605    57 ----elD-----------------------------------------------------------GTRHAPLE-NYLNR 72  blue-green algae
jgi:Emtol_0641  63 ----nvSll-----------------------------------------------------npYNIQDPFYIEkNVFQK 85  Emticicia oli...
CCH02007        58 ----seQsq-----------------------------------------------------rrLGITDPYIVE-KRYNA 79  Fibrella aest...
jgi:Solca_0859  51 ----tpFal------------------------------------------------------sEYGVHEDHIEkESFKI 72  Solitalea can...
jgi:Cpin_4218   55 ----dkRnl-----------------------------------------------------lnHDNTDDYYVEkESFKY 77  Chitinophaga ...
WP_012791141    56 ----gaQsa-----------------------------------------------------yfNNVTDEYHIEkEAFKL 78  Chitinophaga ...
WP_014021326    56 -------------------------------------------------------------------ggDKSVEtDFFSK 68  Cyclobacteriu...
jgi:Ftrac_0420  61 ----fpK-----------------------------------------------------------GEEITVLEtNTYGH 77  Marivirga tra...
Q24NM4          58 pccteeDlikifeplkntkvvldgkeleslyeynryyydfenwelfypenvrvpkaevnkindnIENNKVLDIE-KLWNV 136 Desulfitobact...

XP_013957553    95 -MESHASILFRRIVKth--eeGSTVVTLTRIERNLIRKFLFLLKYRG--------SGFHqrf------------------ 145 Trichoderma v...
WP_015328605    73 -NETIAATLLPRLEAndplteYDGETPLPAADRNVLRQFIVGLFVRS--------AWWRellphvis---------yana 134 blue-green algae
jgi:Emtol_0641  86 -YENRIGIVIDKIAK--------KQSFLTKDDCEKLIFGLVDIKFRN--------PFFR--------------------- 127 Emticicia oli...
CCH02007        80 vAENKYGRLIPRLLK--------KPESITGEEAYNLLFSLLSFKHRN--------PVHRyavsdpqrmraafihsldevn 143 Fibrella aest...
jgi:Solca_0859  73 -QENKYPKFLSELTKf-----SLNSFKIGESTIKLILETIATIKRRN--------PSFGnilkqhvl----------dsy 128 Solitalea can...
jgi:Cpin_4218   78 -QEIGYGKIIGTIIKy-----QRGAQVIDKHRYRLFLETLATIKRRN--------PSTR--------------------- 122 Chitinophaga ...
WP_012791141    79 -QENNYGNIIVLITDf-----YKAPKILNGQAYRLFIETLVTIKRRN--------PSFR--------------------- 123 Chitinophaga ...
WP_014021326    69 -IDGNASAVFKNIIE-------NEKRKLDHEDKIPLIHFVNTFHIRS--------PELI--------------------- 111 Cyclobacteriu...
jgi:Ftrac_0420  78 -FDTRHAKTFHLLNEc-----DLKSNIWSMEVVSSLEEFVPLQYWRS--------PASD--------------------- 122 Marivirga tra...
Q24NM4         137 kYENGWNSLLQFIEQkl---kGTADQEIDEFYKGKLMKFIVSLNWRSfisneslrESFSfintlvdlkdieipfdernvk 213 Desulfitobact...

XP_013957553   146 -yhdKPEDYCS-NDRELLLEYMREH-HFSTPRD----------------------VWYHNLETIMNLEMDSEgk------ 194 Trichoderma v...
WP_015328605   135 ktnqEVKSRTQrELEQDLRQQGFNRtDRRKALRenkkkqpsidsslqeltaswitKVHPQFIINASNQLELA-------- 206 blue-green algae
jgi:Emtol_0641 128 --------------------KSDYVkTIDNVVD----------------------EMINDVFFIEHISKEFNlpielaie 165 Emticicia oli...
CCH02007       144 hqrsSIEPLLKeEGSNWAEFLKDGAkRFETWIT----------------------DPATPLEIQVSNFIRAY-------- 193 Fibrella aest...
jgi:Solca_0859 129 ndvdRIEVFKSmFRSFGAPEDYLQSaSFTDYIN----------------------EFMERFRQDPRGIHDLY-------- 178 Solitalea can...
jgi:Cpin_4218  123 --------EGLiEAFKNGYKSEEGIkRFREYLS----------------------EQTGLKEPVSHLETKIRthfanrsr 172 Chitinophaga ...
WP_012791141   124 --------KALiENFQQRYVTDEALiKFKQFLT----------------------EQIEGTEIQMPSDQQIRqklmthas 173 Chitinophaga ...
WP_014021326   112 -------------------------------------------------------NEIRNFNNSGGKREKVEiksnltek 136 Cyclobacteriu...
jgi:Ftrac_0420 123 ---------------AEFQIKLENAkRLEEFGL----------------------SVYKGNSNQPSTDLELHklils--- 162 Marivirga tra...
Q24NM4         214 rnktASDEMKHnYLLKLFRSFLNDEgLMYDIAK----------------------------------------------- 246 Desulfitobact...

XP_013957553   195 ----------------------wmAKLLQNMFPDDALWFIMHTEQYYMAICTTSEVADeFILTENcynvfegPNTFTRNK 252 Trichoderma v...
WP_015328605   207 ---------------------------------------------KTLPFTIVRVEGLpLLTSDTpciieedPSIFQlhr 241 blue-green algae
jgi:Emtol_0641 166 atylske---nlknntskdlhnlfLLNRHLEEKSIHNYINFLLINLDWQILYSPINNQ-FITSDN-------PGFCLESG 234 Emticicia oli...
CCH02007       194 -----------------------------EQDGTAIHQVTKSLLTRRWFLLHTAASLP-FISSDN-------PGFCVDWE 236 Fibrella aest...
jgi:Solca_0859 179 --------------------------LTGFIDTDSIKNVVRTLYSSKIFVLYAPIGRE-FITSDN-------PGFTITED 224 Solitalea can...
jgi:Cpin_4218  173 d--------------anyqydmylSAFINKGQFTVIAELTNDFYRLKQYILHPPVGWQ-FITSDN-------PGFTIYDG 230 Chitinophaga ...
WP_012791141   174 d--------------paymrdmylSGHLNTSPASGVNSVSIDLYNSKQYILHAPDGLQ-FITSDN-------PGFTFFDG 231 Chitinophaga ...
WP_014021326   137 gnasrkvfekdphddipkiirlfsTIGESTAMSKIYEHEFLKLISSNMMIYENNSKYD-FITSDF-------PLRVINLS 208 Cyclobacteriu...
jgi:Ftrac_0420 163 -------------------esnmpQTLRPALAMSSFGKSHPINDKLEWRLIDQNTQKP-NLTSDN-------PIIFENHP 215 Marivirga tra...
Q24NM4         247 ----------------------------------------GYIKNLTLRLLISSGDIQ-FITSDN-------PSFLYKEN 278 Desulfitobact...

XP_013957553   253 DTgqvtgsshagfHLFAPISPRLIIVLRCLALPSPEEDYQlevsqarhdalwssfqniygpdwkslledlpikkcrnnys 332 Trichoderma v...
WP_015328605   242 ek-------vlgsAFICPLTPHLAFVGALGLKDE---------------------------------------------- 268 blue-green algae
jgi:Emtol_0641 235 MLfntkf--kgnfTFIFPLTSRLALQISANKHSHSKNDLKil-------------------------------------- 274 Emticicia oli...
CCH02007       237 DQvrnlg-fnqskVFFFPLTPRFVLCIRIDQTEPFISNCKrv-------------------------------------- 277 Fibrella aest...
jgi:Solca_0859 225 NQiinfgglgglfEYYFPITPQCCLFITNSIPDENLYMLKei-------------------------------------- 266 Solitalea can...
jgi:Cpin_4218  231 KVvslgg-fegdyEFHFPISPEACLYLNSKHVEDNRLIEKti-------------------------------------- 271 Chitinophaga ...
WP_012791141   232 RVengtg-fgancEFYFPLTPFTCLYINTEEKDTGNELEKai-------------------------------------- 272 Chitinophaga ...
WP_014021326   209 KEesfgvelpslfGMILPLSPKLCLIISNDSDFITEI------------------------------------------- 245 Cyclobacteriu...
jgi:Ftrac_0420 216 KVved-----yrsCAIIPIGKTRTIIRINKELGHFHH------------------------------------------- 247 Marivirga tra...
Q24NM4         279 DRi----------HHIMPVTPQILISVEKDSLHRGKYC------------------------------------------ 306 Desulfitobact...

XP_013957553   333 eiingeahplagydgkhrptdkfhftYHPIGSEYVNIINN-----IFLENAYntSLIAYRNQE 390 Trichoderma virens Gv29-8
WP_015328605   269 --------------------------YATFDSNWSRLFNA-----RIRANAQ--KELIANTKD 298 blue-green algae
jgi:Emtol_0641 275 -------------------------nYLNIPYELVHFINL-----QTAAVAN--NEIYGANEN 305 Emticicia oligotrophica DSM 17448
CCH02007       278 -------------------------wSQFASPVQVAAINR-----CSFVNSY--QRVIGQDRl 308 Fibrella aestuarina BUZ 2
jgi:Solca_0859 267 -------------------------tPRFIDEYFTKKIND-----YSANVSM--KTIIAKNTF 297 Solitalea canadensis DSM 3403
jgi:Cpin_4218  272 -------------------------yHEWIDQSVVHTLNL-----STHAISM--KAIFARDRS 302 Chitinophaga pinensis DSM 2588
WP_012791141   273 -------------------------yPGVIGTDQLKFINE-----STKKLAL--KILIGRDEH 303 Chitinophaga pinensis
WP_014021326   246 --------------------------ISFKQKEFVKQTNI-----ETINTAN--NQIFSKEKT 275 Cyclobacterium marinum
jgi:Ftrac_0420 248 --------------------------------------NIvwqdmIQIYQAH--RYVLSSDKE 270 Marivirga tractuosa DSM 4126
Q24NM4         307 --------------------------VEHIPDDEVERFNL-----IIINNAD--EFVISRNAS 336 Desulfitobacterium hafniense Y51
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