1KEW,1BXK


Conserved Protein Domain Family
RfbB

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COG1088: RfbB (this model, PSSM-Id:224013 is obsolete and has been replaced by 440705)
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dTDP-D-glucose 4,6-dehydratase [Cell wall/membrane/envelope biogenesis]
linked to 3D-structure
Statistics
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PSSM-Id: 224013
Aligned: 45 rows
Threshold Bit Score: 413.546
Created: 7-Oct-2002
Updated: 2-Oct-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1KEW_A     1 MKILITGGAGFIGSAVVRHIIKNTQDT-VVNIDKLTYAGNLESL--SDISESNRYNFEHADICD-SAEITRIFEQY---- 72  Salmonella enterica...
14601230   1 MRVLVTGGAGFIGSSFVRYIVNTTD-WeVLVYDKLTYAGRLENL--HDVID--RIGFMRGDIAD-EEQFGRVLTEF---- 70  Aeropyrum pernix
15807711  14 KSLLVTGGCGFIGSNFVRYWLGQHPeSkVVVYDKLTYAGRKENL--HDLWDNPALSLVVGDIGD-MDLVRRTCQEN---- 86  Deinococcus radiodu...
20091027   4 LKMLVTGGCGFIGSNFIRYMLKKYPdYqIVNLDKLTYAENFANL--RDIENKPNYFFVKGDICD-PASVNEVMTK----- 75  Methanosarcina acet...
20092575   1 MKLLVTGGCGFIGSNFIRYMLGKYPhYqIINLDKLTYAGNPSSL--KDIKNNPNYFFVKGDICD-PIVVNEVMKK----- 72  Methanosarcina acet...
14521381   1 MRILVTGGMGFIGSNFIRYILEKHNdWeVINLDKLTYGSNPANL--KDIQDDPRYTFVKGDVAD-FELVRELIKK----- 72  Pyrococcus abyssi
14590332   4 MKLLVTGGMGFIGSNFIRYILEKHPdWeVINIDKLGYGSNPANL--KDLEDDPRYTFVKGDVAD-YELVKELVRK----- 75  Pyrococcus horikoshii
19113649  10 GYALITGGAGFIGSNFLDYAVDKYPDFhFTCIDKLSYVSNYTTVflSKVLNQPNFRFLEMDLATnYKFLYQFMVEDsein 89  fission yeast
15897730   1 MKIIVVGGAGFIGSAFVRELNKRGIKp--IVVDLLTYAGRKEN-----LIGT-DYDFVQADVR--SEKMHDIIKEY---- 66  Sulfolobus solfatar...
15898578   1 --MIIIGGAGFIGSAFVREVNKRGIKp--IVVDLLTYAGRKEN-----LIGT-EHEFIRADVR--SEEIHDIVKNS---- 64  Sulfolobus solfatar...
1KEW_A    73 QPDAVMHLAAESHVDRSITGPAAFIETNIVGTYALLEVARKYWSAlgedkknnFRFHHISTDEVYGDLPHPDEvensvtl 152 Salmonella enterica...
14601230  71 EPDVVVNFAAETHVDRSINEPAPFMRTNIIGVFTILEAIRKRIDQ--------IVLLHVSTDEVYGDLWNTGK------- 135 Aeropyrum pernix
15807711  87 DVDLIVNFAAETHVDQSILGPLVFTETNVRGTHVLLEVARELG----------IRLHHISTDEVYGHIKDGH-------- 148 Deinococcus radiodu...
20091027  76 -VDQVVHFAAESHVDRSIEDGSVFVRTNVLGTNTLLQSALANK-I--------KKFIHVSTDEVYGSAMEG--------- 136 Methanosarcina acet...
20092575  73 -VDHVVHFAAESHVDRSIEDGSVFVRTNVLGTNTLLQSALANN-I--------KKFVHISTDEVYGSIKEG--------- 133 Methanosarcina acet...
14521381  73 -VDAIVHFAAESHVDRSISSPDNFLHSNVIGTYTLLEAIRKENPG--------VRLVHISTDEVYGDILKG--------- 134 Pyrococcus abyssi
14590332  76 -VDGVVHLAAESHVDRSISSPEIFLHSNVIGTYTLLESIRRENPE--------VRFVHVSTDEVYGDILKG--------- 137 Pyrococcus horikoshii
19113649  90 KITHIINFAAESSVDRSFIDPLYFTKNNILSTQNLLECVRILLGKkeel-rnrLNFVHVSTDEVYGEQDENAS------- 161 fission yeast
15897730  67 SPDIVINFAAETHVDRSIYKPQDFVTTNVLGTVNLLEASRKFN----------FKYVHISTDEVYGEECGD--------- 127 Sulfolobus solfatar...
15898578  65 --DIVVNFAAETHVDRSIYRPQDFVTTNVLGVVNLLEAARKYD----------FKYVHISTDEVYGEECAD--------- 123 Sulfolobus solfatar...
1KEW_A   153 pLFTETTAYAPSSPYSASKASSDHLVRAWRRTYGLPTIVTNCSNNYGPYHFPEKLIPLVI----------LNALEGKPLP 222 Salmonella enterica...
14601230 136 -EATESDPLNPSSPYSASKASGDLLIKAYGRTYGLKYRIVRPCNNYGPYQHVEKLIPRTI----------IRILHGKPPV 204 Aeropyrum pernix
15807711 149 -QSVETDELAPRSPYAASKAAADQLVQAYAITYGIPVTITRGANNVGPYQYPEKAVPLFS----------TNAILGEPLP 217 Deinococcus radiodu...
20091027 137 -SFTEMDNLNPSSPYSSSKASSDLLAKSYHTTYGLPVCITRCTNNFGPYQYPEKLIPFFI----------SRLMEGKKVP 205 Methanosarcina acet...
20092575 134 -SFTETDKLNPSSPYSSSKAGSDLLAMSYYTTYGLPVCITRCTNNFGPYQYPEKLIPFFI----------SRLAEGKKVP 202 Methanosarcina acet...
14521381 135 -SFTEEDRLMPSSPYSATKAASDMLVLGWARTYGLNASITRCTNNYGPYQFPEKLIPKTI----------IRAKMGLKVP 203 Pyrococcus abyssi
14590332 138 -SFTENDRLMPSSPYSATKAASDMLVLGWTRTYNLNASITRCTNNYGPYQFPEKLIPKTI----------IRASLGLKIP 206 Pyrococcus horikoshii
19113649 162 --VDEKSKLNPTSPYAASKAAVDLIIQSYRYSYKISVTVIRANNVYGPRQYEEKLIPMTLgklkkfinqkSQKIMQDKIT 239 fission yeast
15897730 128 ----ENSPLKPSSPYSASKASADLFVKAYVRTYGISAVIVRPSNNYGPRQFPEKLIPKAI----------IRTLLGIHIP 193 Sulfolobus solfatar...
15898578 124 ----EDSPLQPSSPYSASKASADLFVKAYVRTYGIKAIIVRPSNNYGPRQFPEKLIPKVI----------IRTFLNMHVP 189 Sulfolobus solfatar...
1KEW_A   223 IYGKGDQIRDWLYVEDHARALHMVVTE-----------GKA-GETYNIGGHNEKKNLDVVFTICDLLDEIVPKat--sYR 288 Salmonella enterica...
14601230 205 IYGDGSQIRDWLYVEDTARAIHVVLEK-----------GVD-GEIYNVCGGMASTVKDIVVNILESMGKPRD-------- 264 Aeropyrum pernix
15807711 218 VYGDGQQMRDYAHVYDHCTGIETVLLR-----------GNI-GEVYNVGTGREMTNLEMVDIVLETLGKDHS-------- 277 Deinococcus radiodu...
20091027 206 VYGTGLNIRDWIYVEDHCSAVDFILHN-----------GKS-GEIYNIDGGNELTNLEITHRLLKMLGKDES-------- 265 Methanosarcina acet...
20092575 203 VYGTGLNIRDWIYVEDHCSAVDFVLHN-----------GSS-GEVYNIDGGNELTNLEITHRLLKMLGKDES-------- 262 Methanosarcina acet...
14521381 204 IYGTGKNVRDWLYVEDHVRAIEAVLLK-----------GEA-REIYNISAGEERTNLEVVRTILRIMDKDES-------- 263 Pyrococcus abyssi
14590332 207 IYGTGKNVRDWLYVEDHVRAIELVLLK-----------GES-REIYNISAGEEKTNLEVVKIILRLMGKGEE-------- 266 Pyrococcus horikoshii
19113649 240 LHGDGLHKRKYLHIYDFINAIDLVWMKqgsevyhstleSKMsGQIFNIGSDDEIDNLSLVKFICDYFLYRKLSlknldYS 319 fission yeast
15897730 194 VYGDGKAERDWIFVEDTARIIFDVVSR-----------AEWkGEVYNIPGGQRYNVLEILKMLEEVSGKEVK-------- 254 Sulfolobus solfatar...
15898578 190 IYGDGRAERDWIYVEDTVRIIYDIMER-----------SEWrGEVYNIPGGQRYSVLDVIKIIGEIMGKEVK-------- 250 Sulfolobus solfatar...
1KEW_A   289 EQITYVADRPGHDRRYAIDAGKISRELGWKPLETFESGIRKTVEWYLANTQWVNNVKSGAYQSWIEQNYE 358 Salmonella enterica subsp. en...
14601230 265 -YLVYGKSRPGEDRRYAMKCDK-IRNLGWAPHVTLKEGLKITVKWYIENRWWWRPLLDKRYVLADHPW-- 330 Aeropyrum pernix
15807711 278 -LVKHVTDRPGHDRRYSMNVDK-LRSLGWQPKYDPKQAVAEAARWYEGNRWWWEPIRSGEFREYYNRQYA 345 Deinococcus radiodurans
20091027 266 -SIEYVEDRKGHDFRYSLDGGK-LEKMGWKPQYDFDTALEQTDSWYVENKWWWEPLKR------------ 321 Methanosarcina acetivorans C2A
20092575 263 -SIEYVEDRKGHDFRYSLDGSK-LKKMGWKPQYDFDTALEQTARWYVENRWWWEPLKR------------ 318 Methanosarcina acetivorans C2A
14521381 264 -LIEFVEDRPGHDIRYSLDSWKIIRELKWRPKYRFEEGIKKTVEWYLENEWWWKPLINERVLHPTPWKLE 332 Pyrococcus abyssi
14590332 267 -LIELVEDRPGHDLRYSLDSWKITRDLKWRPKYTFDEGIKKTIDWYLKNEWWWKPLVDERILHPTPWKLK 335 Pyrococcus horikoshii
19113649 320 KYITFVQDRNYNDSRYSLNYEK-IKSLGWRPQIPLETGLRKLIDEYY----------------------- 365 fission yeast
15897730 255 --IKFVSDRPGHDRRYCMT-TSMKYEVTPFKe-----GLRRTYEWYLNNRWWWEPLINDKFFVEDEPWLT 316 Sulfolobus solfataricus
15898578 251 --VKFVDDRPGHDKRYCMT-TKLKYEVTPLKe-----GLRKTVEWYLNNRWWWEDLIKDKFFTEDEPWKK 312 Sulfolobus solfataricus
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