1AOB


Conserved Protein Domain Family
ThyA

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COG0207: ThyA 
Thymidylate synthase [Nucleotide transport and metabolism]
Thymidylate synthase is part of the Pathway/BioSystem: Thymidylate biosynthesis
Statistics
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PSSM-Id: 439977
Aligned: 455 rows
Threshold Bit Score: 229.991
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1AOB_A         1 MKQYLELMQKVLDEGTQKND-RTGTGTLSIFGHQMRFNLQDG-FPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHEnNVT 78 
WP_011044375   1 MRAYLDLCQRIIDQGTWVENeRTGKRCLTVINADLEYNVGNNeFPLITTRKSFFKSAIAEFIGYIRGYDSAADFRKlGTK 80 
NP_439065      1 MKQYLELCRRIVSEGEWVANeRTGKHCLTVINADLEYDVANNqFPLITTRKSYWKAAIAEFLGYIRGYDNAADFRAlGTK 80 
WP_004245521   1 MKQYLALCQRIIDEGEWIDNkRTGTRCLTVINADLEYDVANNqFPLITTRKSFYKAAIAELLGYLRGYDNAAQFRAiGCN 80 
WP_013087743   1 MKQYIDLCRKIIHEGCWIKNnRTKTRCLTIINADLEYDVENNqFPLITTRKISYKSAISEMIGHIRGYRSAKQFRDlGCN 80 
WP_004242187   1 MEQYLDIAKRILEEGKWIENkRTGKRCLTIINADFTYHVDKNeFPLVTTRKAFWKAAIAEMLGYLRGYDSAAQFRAiGCN 80 
WP_066283482   1 MKQYLDLCQRIINEGKWIENqRTKAKCLTVINVDFEYDVKNNqFPLITTRKSFYKSAIAELLGYLRGYVSAAQFRNiGCN 80 
WP_068545758   1 MKQYLDLCQRIIDEGSWVSNeRTGKRCLTLINADLEYQVGKNeLPIITTRKSFYKAAIAELLGYIKGYDNAADFRAlGTP 80 
WP_089073265   1 MNQYLELCKKIINDGQWVENkRTNKKCLTLINADLQYDVENNvFPIITTRKSFWKSAIAELLGYIRGYDNAADFRKlGTK 80 
WP_071565319   1 MKRYIDIGKRILEEGVWLSNaRTGKKTLSIIGASFEYDLADGtVPVVTTKKLFWKTAIAEMLGYLRGYQSAAQFRElGCN 80 
1AOB_A        79 IWDEWADE------------NGDLGPVYGKQWRAWPT-PDG----------------------------RHIDQITTVLN 117
WP_011044375  81 TWDANANLndawlnnthrkgEDDMGRVYGIQGRAWAK-PDG----------------------------GTIDQLKKIVD 131
NP_439065     81 TWDANANEnaawlanphrrgVDDMGRVYGVQGRAWRK-PNG----------------------------ETIDQLRKIVN 131
WP_004245521  81 TWNANANEnsawlnnphrkgEDDMGRVYGVQGRQWQR-PDG----------------------------SHFDQLRKVVD 131
WP_013087743  81 VWEANANQnkswlsnpyrkgRDDLGRIYGVQGRSWKK-HDG----------------------------SHLDQLRKVIQ 131
WP_004242187  81 TWNANANEntdwlanpnrkgEDDMGRVYGVQGRQLKV-SPTeaqydlllslndsgdkegvktlinelrkNTFDQLRKVYD 159
WP_066283482  81 TWNANANQnqawlnnpnrkgTDDLGRIYGVQGRSWRL-HDG----------------------------TFLDQLKKVIN 131
WP_068545758  81 TWNANANEneawlnnphrkgEDDMGRVYGVQGRAWAK-PDG----------------------------GSVDQLKKVVD 131
WP_089073265  81 SWDANANDnsvwlsnpnrkgLDDMGRVYGVQGRSWVN-SDG----------------------------CVIDQLKKIIN 131
WP_071565319  81 TWNANTNEnqawldnphrkgKDDMGLCYGAIGRAFPGiEDD----------------------------KPFDQYQKIVT 132
1AOB_A       118 QLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLSCQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVG 197
WP_011044375 132 NLKDGIDDRAEIMTFYNPGEFHMGCLRPCMHTHNFSLLGDTLHLTSFQRSCDVPLGLNFNQVQVFVFLALMAQITGKKAG 211
NP_439065    132 NLTKGIDDRGEILTFFNPGEFDLGCLRPCMHTHTFSLVGDTLHLTSYQRSCDVPLGLNFNQIQVFTFLALMAQITGKKAG 211
WP_004245521 132 NLTNGIDDRGEIVTFYNPGETALGCLRPCMHTHTFSLLGDRLYLTSYQRSCDVPLGLNFNQIQCFVLLALVAQITGHKPG 211
WP_013087743 132 HLKDGIDDRAEIITFYNPGEIEMGCLIPCMHTHTFSILDKKLYLTSYQRSCDVPLGLSFNQIQCFILLALVAQITNYKPG 211
WP_004242187 160 NLKKGIDDRGEIISFWNPGEFNQGCLRPCMFMHHFSVLDGTLYLNSYQRSCDYALGYVFNAPQCYFLLAIMAQITGLKCG 239
WP_066283482 132 NLSIGIDDRAEIITFYNPGELELGCLRPCMHTHHFSLLSNELYLTSYQRSCDVPLGLNFNQIQCFVLLALVAQITSLIPG 211
WP_068545758 132 NLTKGIDDRGEIISFYNPGEFHMGCLRPCMFQHQFSLLDGTLYLNSYQRSCDVPLGLNFNQIQVFAFLAIMAQITGHKAG 211
WP_089073265 132 NLNSGIDDRGEILTFYNPGEFDKGCLRPCMHTHTFSLINEDLYLTSYQRSCDVPLGLNFNQIQVFTLLKLVAQITRKKPK 211
WP_071565319 133 DLSRGIDDRREIMTFNHPNLIHRACLPACMHTHHFNLLGDDLYLESYQRSSDYALGQPFNHFQVAFLLLITAQITGKKAK 212
1AOB_A       198 DFVWTGGDTHLYSNHMDQTHL-QLSREPRPLPKLIIKRKpeSIFD----YRFEDFEIEGYDPHPGIKAPVAI 264
WP_011044375 212 MAYHKIVNAHIYEDQLPLMKEvQLKREPLALPKLIINPEikSLEDletwVTMDDFKVEGYECHEAIKYPFAV 283
NP_439065    212 KAYHKIVNAHIYEDQLELMRDvQLKREPFPLPKLEINPDikTLEDletwVTMDDFKVVGYQSHEPIKYPFSV 283
WP_004245521 212 KAFHKIVNAHIYENQLPLMRDvQLKREPLPLPKLHINPNikTLDDietwVTTDDFSVEGYQCHEAIKYPFTV 283
WP_013087743 212 KVYHKIVNAHIYENQLSLMRDvQLKRSPYPLSKLIINPKikKLEDienwVSSDDFKVINYRFHGKISYPFNV 283
WP_004242187 240 KVYHKVVNLHLYEDQLELMRDvQIARKPFASPKLHINPDikTLDDlmtwVTTDDFTVTDYQHHDPIKYPFSV 311
WP_066283482 212 KVYHKIVNAHIYDNQLQIMRDiQLKRTPYSLPQLYINPAikTLKDietwVSSNDFNVINYQHHEPIKYPFTV 283
WP_068545758 212 VAYHKIVNAHIYEDQLELMENvQLKREPYPSPQLRINPKirSLEDletwVTMDDFEVIGYQHHDPIQYPFSV 283
WP_089073265 212 TAYHKIVNAHIYEDQIDLMKv-QIERKPFQSPSLNINPDikSLEDleswVTLDDFEVIGYEHHDAIKYPFSV 282
WP_071565319 213 KMRHHLSNVHLYEDQVEIFKNeQVKREPLSPPSLKINPAikTLKDletwVTMEDFELINYKHHPVVKYPFTV 284
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