4Q1J,3HP0,1SG4,2HW5


Conserved Protein Domain Family
ECH_1

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pfam00378: ECH_1 
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Enoyl-CoA hydratase/isomerase
This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.
Statistics
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PSSM-Id: 395302
Aligned: 9 rows
Threshold Bit Score: 268.074
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4Q1J_C  29 EIESAIIQVKMQDRtHKNAFSQELTDDLIQAFEYIRQNPKYKAVILTG-YDNYFASGGTQEGLLR-----IQQGLTKFTD 102 Bacillus subtilis sub...
P31551   8 TRNGSILEITLDRP-KANAIDAKTSFEMGEVFLNFRDDPQLRVAIITGaGEKFFSAGWDLKAAAEg---eAPDADFGPGG 83  Escherichia coli K-12
P23966  16 ETYNGIAKITINRPeVHNAFTPKTVAEMIDAFADARDDQNVGVIVLAGaGDKAFCSGGDQKVRGHgg-yvGDDQIPRLNV 94  Bacillus subtilis sub...
P24162   9 EISEGLAVITLDRPeVMNALNAAMRHELTAALHRARGE--ARAIVLTG-SGRAFCSGQDLGDGAAeg--lNLETVLREEY 83  Rhodobacter capsulatu...
3HP0_E  12 RFQASVCYITFHRPeANNTINDTLIEECLQVLNQCETS-TVTVVVLEG-LPEVFCFGADFQEIYQexkrgRKQASSQEPL 89  Bacillus subtilis
P42125  39 EGPAGVAVMKLRNP-PVNSLSLECLTEFTISLEKLENDKSIRGVILTSeCPGIFSAGLDLLEMYGrn--pAHYAEYWKNV 115 house mouse
1SG4_A  10 DAGAGVAVMKFKNP-PVNSLSLEFLTELVISLEKLENDKSFRGVILTSdRPGVFSAGLDLTEMCGrs--pAHYAGYWKAV 86  human
2HW5_A  38 GKNNTVGLIQLNRPkALNALCDGLIDELNQALKIFEEDPAVGAIVLTG-GDKAFAAGADIKEMQNl----SFQDCYSSKF 112 human
P34559  40 GEKQNVALIKLNRPkALNALCAQLMTELADALEVLDTDKSVGAIVITG-SERAFAAGADIKEMTNn----EFATTFSGSF 114 Caenorhabditis elegans
4Q1J_C 103 DNLYSLALDCEIPVIAAMQGHGIGGGFVMGLFADIVILSRESV--YTANFMKYGFTPGMGATFIVPKKLGFSLAQEILLN 180 Bacillus subtilis sub...
P31551  84 FAGLTEIFNLDKPVIAAVNGYAFGGGFELALAADFIVCADNAS--FALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVMT 161 Escherichia coli K-12
P23966  95 LDLQRLIRVIPKPVVAMVSGYAIGGGHVLHIVCDLTIAADNAI--FGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYL 172 Bacillus subtilis sub...
P24162  84 EPLLQAIYSCPLPVLAAVNGAAAGAGANLALAADVVIAAQSAA--FMQAFTRIGLMPDAGGTWWLPRQVGMARAMGMALF 161 Rhodobacter capsulatu...
3HP0_E  90 YDLWXKLQTGPYVTISHVRGKVNAGGLGFVSATDIAIADQTAS--FSLSELLFGLYP-ACVLPFLIRRIGRQKAHYXTLX 166 Bacillus subtilis
P42125 116 QELWLRLYTSNMILVSAINGASPAGGCLLALCCDYRVMADNPKytIGLNESLLGIVAPFWFKDMYVNTIGHREAERALQL 195 house mouse
1SG4_A  87 QELWLRLYQSNLVLVSAINGACPAGGCLVALTCDYRILADNPRycIGLNETQLGIIAPFWLKDTLENTIGHRAAERALQL 166 human
2HW5_A 113 LKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQ--FAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLT 190 human
P34559 115 LSNWTAVSDVKKPVIAAVNGFALGGGNELAMMCDIIYAGEKAR--FGQPEINIGTIPGAGGTQRWARAAGKSFAMEVCLT 192 Caenorhabditis elegans
4Q1J_C 181 AGSYRGADLEKRGVPFKVLPR-AEVLDYAVELAQELAEKPRNSLVTLKDHLVAPLR-DQLPRVIEQELMMAEKTFHHEEv 258 Bacillus subtilis sub...
P31551 162 GRRMGAEEALRWGIVNRVVSQ-AELMDNARELAQQLVNSAPLAIAALKEIYRTTSEmPVEEAYRYIRSGVLKHYPSVLHs 240 Escherichia coli K-12
P23966 173 CRQYNAQEALDMGLVNTVVPL-EQLEEETIKWCEEMLEKSPTALRFLKAAFNADTDgLAGIQQFAGDATLLYYTTDEAK- 250 Bacillus subtilis sub...
P24162 162 AEKIGAEEAARMGLIWEAVPD-VDFEHHWRARAAHLARGPSAAFAAVKKAFHAGLS-NPLPAQLALEARLQGELGQSADf 239 Rhodobacter capsulatu...
3HP0_E 167 TKPISVQEASEWGLIDAFDAEsDVLLRKHLLRLRRLNKKGIAHYKQFXSSLDHQVS-RAKATALTANQDXFSDPQNQ--- 242 Bacillus subtilis
P42125 196 GTLFSPAEALKVGVVDEVVPE-DQVHSKARSVMTKWL-AIPDHSRQLTKNMMRKATaDNLIKQREADIQNFTSFISKDSi 273 house mouse
1SG4_A 167 GLLFPPAEALQVGIVDQVVPE-EQVQSTALSAIAQWM-AIPDHARQLTKAMMRKATaSRLVTQRDADVQNFVSFISKDSi 244 human
2HW5_A 191 GDRISAQDAKQAGLVSKICPV-ETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFE-MTLTEGSKLEKKLFYSTFATDDr 268 human
P34559 193 GNHVTAQEAKEHGIVSKIFPA-DQVVGEAVKLGEKIADQSPLIVQMAKEAVNKAYE-LTLQEGLHFERRLFHATFATKDr 270 Caenorhabditis elegans
4Q1J_C 259 ksriKGLYG---------------N 268 Bacillus subtilis subsp. subtilis str. 168
P31551 241 edaiEGPLAfaekrd----pvwkgR 261 Escherichia coli K-12
P23966 251 ----EGRDSfkekrkpdfgqfprfP 271 Bacillus subtilis subsp. subtilis str. 168
P24162 240 ---rEGVQAflekrp----phftgR 257 Rhodobacter capsulatus SB 1003
3HP0_E 243 ----XGIIRyvetgq----fpwedQ 259 Bacillus subtilis
P42125 274 ---qKSLHMylek--------lkqK 287 house mouse
1SG4_A 245 ---qKSLQMylerl------keekG 260 human
2HW5_A 269 ---kEGMTAfvekrk----anfkdQ 286 human
P34559 271 ---kEGMTAfaekrk----pqwesK 288 Caenorhabditis elegans
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