Conserved Protein Domain Family
DUF4500

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pfam14937: DUF4500 (this model, PSSM-Id:405605 is obsolete and has been replaced by 434330)
Domain of unknown function (DUF4500)
This family is found in eukaryotes. The function of this protein remains unknown. The gene which encodes for this protein is named chromosome 6 open reading frame 162 (C6orf162) and is found between the chromosomal positions 6q15-q16.1. It is thought that this protein may be an important part of membrane function.
Statistics
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PSSM-Id: 405605
Aligned: 18 rows
Threshold Bit Score: 135.12
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_002603789   19 AGPRSPGLRHVQTTTLFRVVNPELFMRPNKMVMAFGLVTITGCIAYLAYMNASKENQRdqLYVNVSSDGTETVQRRRSKW 98   Florida lancelet
XP_006560007    7 KVIPGDGLRSLKSTMLFRAINYELYVKPNKIIMIFGTIAMFGCVGYIVYMQHNSNNTK--YYSVINSNETIDLKKKTSKW 84   honey bee
EGI63320        7 ETTPGDGLRSLRSTTLFRAVNFELYVKPNKTIMILGIIAMLSCSGYIFYMNTNKKKND--YHIMVKSDETLELVKKVSKW 84   Panamanian le...
EFX69126       12 PRVAGDGLRSVKTTGVFRALNFELYVKPNKVIMVLGLLAIAGCTGYLTYMKTKYENMG--YYVAVREDGSKQLHTKKSRW 89   common water ...
XP_001604253    8 KHTPGDGIRSLKSTPMFRAINYELYVKPNNVVMALGVIAMTGCVGYILYMRSKYESMG--YYTAVEADGKETFKKKVSKW 85   jewel wasp
ETN58991        7 TAAPGDGIRSMRSTNVFRAINFELYAKPNVVVMGIGLVCLSITFGYIAYMRSKYEGLG--YYTAVQEDGKEVFVKRKSKW 84   Anopheles dar...
1_pfamImport    4 GAAAGDGIRSIKTTNVFRLINFELYTKPNLVIMCLGGAALAGVFGYIAYMRHKYEALG--YYVAVQEDGKEVFTKKQSKW 81  
XP_002047464    6 TQKPGEGIRSMRSTSVFRLINFELYTKPNKIIMGLGLAAITGVFGYIAYMRYKYENLG--YYVAVREDGREEFVKKKSNW 83   Drosophila vi...
EFA03274        6 APAPGEGLRSLRSTTLFRAVNFELYVKPNLVIMGLGLVAFTGCLGYIAYMRNKYDALG--YYPAIQEDGREEYVKRKSKW 83   red flour beetle
XP_002426145    6 SSKPGEGIKSLKTSSLFRALNFELYVAPNKFIMGLGASAFGICVGYIMYMRYKYEGLG--YYPGVNADGTENYYKRKSNW 83   human body louse
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