5SVL


Conserved Protein Domain Family
P2X_receptor

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pfam00864: P2X_receptor (this model, PSSM-Id:395693 is obsolete and has been replaced by 459968)
ATP P2X receptor
Statistics
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PSSM-Id: 395693
Aligned: 68 rows
Threshold Bit Score: 363.023
Created: 22-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5SVL_A          7 FTYETTKSVVVKSWTIGIINRVVQLLIISYFVGWVFLHEKAYQVRDTAIeSSVVTKVKGSGLY--AN------------- 71 
CDS40794       17 FDYETQKVVQINSFKIGFTYRLIQLGIVLYVVFWVMYYEKGYQAFDEAV-SGVTAKLKGIAFS--NStksn------iga 87  Echinococcus m...
CDS42078       11 FTYETPKMVEITNYKIGIFHRLLQIAITVYVVCWVLIYDKGYQENDEVM-SSTVTKTKGLMVE--RWaqnee-----dva 82  Echinococcus m...
XP_001743535   18 LEYDTLKTVHIRSKKVGLIFRLLQITILAYVVGYGIIYQKGYQEVDSAV-STVLTKVKGIAITcdNTdissmndcvpgdl 96  Monosiga brevi...
EDO41363       13 LEYNTSKIVHIKSKKVGLINRLIQLAIIGYIIGYVIIYKKGYQEVEKPY-SSVTTKLKGTSFT--NLtgnesf-plyggp 88  starlet sea an...
EFX89098       12 FWYETPKVVHIRSKKVGILGRFLQLCVLSYIVGYVMVYNKGYQEFANVE-SAVVTKVKGVAFT--NTnknip----eiyr 84  common water flea
XP_003384136   19 FEYDTPKFVHIRNKKVGLLNRLVQLAIVGYIIGYGIVWENGAQDKEPVQ-SVVTTKVKGVSVL--NAtrqfmt--dcnew 93  Amphimedon que...
15_pfamImport   1 FEYKTAEYVATKNKTVGVLYRLLQLLIISYIIGWVFVSRKSYQETDEAVqSSVVTKVKGVSVT--NTtds--------gl 70 
XP_004994999   18 LEYDTLKTVHIKSKKVGLIFRILQLVILGYIIGYAIIWQKGYQAADQAV-STVYSKVKGVAVTcnDLnvtsirncsdsdi 96  Salpingoeca ro...
NP_945336      13 FNYTTVRYVVTQNKIVGLLYRFFQLIIMCYLIGWVFVTKKGYQVVDDTIeSSVVTKVKGIARV--NTtf----------s 80  zebrafish
5SVL_A         72 RVMDVSDYVTPPQGTSVFVIITKMIVTENQMQGF--CPE-----SEEKy---RCVSDSQC-GPERLPGG-GILTGRCvn- 138
CDS40794       88 IVWDAADYVIPPQQRSAFFVMTNLVTTSGQTLGT--CEEsh--dVAGN----DCKSDKDCeAGRIVMVGnGVQTGICvps 159 Echinococcus m...
CDS42078       83 iISDAADIVNPPLENNAFFVTTHRILTPRQTSSR--CPGi----RNSKk--sSCGRDGDCeKMQLSLSEaGARTGKCvd- 153 Echinococcus m...
XP_001743535   97 RVWDTPDYIKPAQENDAFFVVSNSIQTSKQTQRAegWDEdpaapVTGSasafNCTSDADCp--RFATSRnGALTGEC--- 171 Monosiga brevi...
EDO41363       89 FVWDQADYVIPPEENDAFFVATNMVITPDQRQGT--CPEsp--dIANV----KCTRDENCtRMEETSYGhGFQTGKCvps 160 starlet sea an...
EFX89098       85 RIWDTSDLIVPPSENDAFFITTNIIITPNQTRGA--CSEdp--dVYGA----LCDSPQNCiRGQSLPIGnGAMTGRCips 156 common water flea
XP_003384136   94 pILDHVDLIVPAQEPNSFFVTTNLWATCNQKYGV--CPEls--tIPDA----VCLTNDSCpPGIIYRTGnGVTTGECtg- 164 Amphimedon que...
15_pfamImport  71 LLWGPEDYVIPPQGEDVLFVVTNFLETPNQTLGY--CAEsv--kVLDG----RCRGDDDCeEGKMVTAGnGIMSGRClt- 141
XP_004994999   97 RVWDTADYVIPPQESNAAFIVTNSVQTSNQTQQPggWPEdpdasTKGSqrayTCEKNADCeAVRFSPSRnGAVSGKC--- 173 Salpingoeca ro...
NP_945336      81 DLWGPEEYVIPDHGGKFLFVVTNFIETPNQTLTT--CPEsp--sVPFS----TCTHDDNCtEGEAVRAGnGIKTGTCrk- 151 zebrafish
5SVL_A        139 -ySSVLRTCEIQGWCPTEVDTVe----------TPIMMEAENFTIFIKNSIRFPLFNFE--KGNLLPNl-TARDMKTCRF 204
CDS40794      160 trKANLSVCEIYGWCPTEHDVLp---------nDFILANAPNFTVMLKNSIEFPQYHVK--RRNILGWm-DKHFLSTCRY 227 Echinococcus m...
CDS42078      154 -fHDGKGVCEIYAWCPLENDTIvls-----ynlQTRFEMISNYTVYIKNDIEYPKFHIK--RRNRDAWv-SEKPLGSCRY 224 Echinococcus m...
XP_001743535  172 --NTTTERCRIYGWGPVESKDEddrattdglfyARHMPAVKNFTVYIKNTVFFQRFGAKfgSTDESDK--VDVY--TCTW 245 Monosiga brevi...
EDO41363      161 dqEKGIKVCEVFAWCPVELDITp----------mPQFPSLKNFTVLIKNTVQFPSFGVS--KRNIAPDa-DTSTLKSCQY 227 starlet sea an...
EFX89098      157 daNSSVNVCEIFAWCPIEQDIFplg------tdRPLLEETADFTVLIKNFIEFPTFGKTfrRRNIMKDa-NKTYLQSCHY 229 common water flea
XP_003384136  165 ----fNETCQIRGWCPVEDENDtl-------tdEGPIIDTKDFTVLVKNSISFPKLDSSyrVRNIPERanNKSYLSGCQF 233 Amphimedon que...
15_pfamImport 142 kgGNSTGSCEVFSWCPIEKEYKh---------qDPLLTNAENFTIYIKNFIHYSKFNFS--KSNVLQTt-NKSYLKGCRY 209
XP_004994999  174 --DLATKRCMVYGWGPVELSKDddasq--vlgyPRQMPQVKNFTMFIKNTIFFPHFQRKfgNTGLGNS--SASYLKSCLW 247 Salpingoeca ro...
NP_945336     152 tdGNETNTCEIYGWCPTEKPRRe---------aATMLREAENFTVYIRNFIKFSQFNLS--KTNILKEg-YPSYIKTCLH 219 zebrafish
5SVL_A        205 HPD-KD--PFCPILRVGDVVKFAG-QD--FA-KLARTGGVLGIKIGWVCDLDKAWD-QCIPKYSFTRLDSvSe-KSSVSP 275
CDS40794      228 NPN-KEklKYCPIFRLADIMEYTE-AE--NK-QIWNKGGMVSIHIEWNCNLDYNEE-QCLPKYIFRRLDD-F--DNPVGK 298 Echinococcus m...
CDS42078      225 NPS-DEldKYCPIFRLGTIFEEVG-LK--PS-ALT-RGGVIGIIINWDCNLDWGAG-NCKPSYSFTNLDV-D---NDGNS 293 Echinococcus m...
XP_001743535  246 SPTgLE--RHCPIFKIDTILNEAGiTD--FEnQAMRNGALITIQVNYDCNLDSSAH-TCSPTYKFTRLDT-K---SDLSA 316 Monosiga brevi...
EDO41363      228 DKD-TS--PLCPIFRLETITKEAG-QD--FN-KLAYKGGVIGIIITWNCDFDSLLY-SCKPVYSFRRLDN-A--NAPIAK 296 starlet sea an...
EFX89098      230 NQE-RD--PFCPVFRIEDIVSFAG-EN--FT-QLAIRGGVIVISIDWNCNLDLDFLeFCKPIYSFRRADD-P--NTNIAP 299 common water flea
XP_003384136  234 DPD-SEmgLFCPIFSLKQIVDMINsSDgyYE-SLATKGAVVGLEISWDCNLDRSPT-HCVPKYSARRLDN-P--NAQISN 307 Amphimedon que...
15_pfamImport 210 DEE-LH--PYCPIFRLGDITRRAG-HN--FQ-DVATLGGSIGIMIEWNCDLDKGAS-NCNPQYSFTRLDV-TdsNDAIEA 280
XP_004994999  248 NES-TD--RYCPVFRIEDILSAAGvKS--FEqDVMMAGAVITVQIRYDCNLDKNVE-TCAPEYRFTRIDE-P--NNTLSN 318 Salpingoeca ro...
NP_945336     220 DEI-HH--PYCPVFRLGDIVSKAG-YR--FE-EVAAKGGSIGIVIKWSCDFDMDTS-DCHPQYSFMSMGS-S---TPVTA 287 zebrafish
5SVL_A        276 GYNFRFAKYYKmeNGSEYRTLLKAFGIRFDVLVYGNAGKFNIIPTIISSVAAFTSVGVGTVLCDIILLNFLKGADQYKAK 355
CDS40794      299 GWNFRFSQHYMe-GNVRKRNLIKAYGIQFFITVYGKGGRFHLLTFSMNLGSGLALLGIATVLCDTIVLNITRKREVYRSA 377 Echinococcus m...
CDS42078      294 GFNFRYAYRYRe-NGTLYRDLVKAIGLRFSIFVHGQAGRFSIIPLLLNLGSGLALLGMAPTICDIIILNIVGSKNVYKDA 372 Echinococcus m...
XP_001743535  317 GYNFRFANYQId---PPARDLYKVYGLRFVFVVSGTAGRFSMVPLLVALGSGLGLLGLATVIADLLVTKCIRNANVYYGL 393 Monosiga brevi...
EDO41363      297 GYNFRHANYYVk-NDTLHRTLFKAYGIRFVVTVTGQGGKFNVVPLFLNLGSGLALLSIATVLCDVVVLYVLRRKEFYREK 375 starlet sea an...
EFX89098      300 GWNFRHANYHEe----NRRTLVKSYGIRFVIEVRGQGRKFNILPTMLNIGSGLALLGVTTVVCDFIILYFTKKRMFYKGV 375 common water flea
XP_003384136  308 GFNFRYPRYYRdqNGDDVRDVWKVYGIKFEIVVTGEGRKFSFTTLVLALGSTIALLAIATTVTDVIALYLLKKGTYYREK 387 Amphimedon que...
15_pfamImport 281 GFNFRHTRYFKtaAGESYRSLFKVYGIRFNIMVHGEAGKFSIIPTLLNVASGMTLTGAGAFLCDIVFFYLKKRSDSYQAR 360
XP_004994999  319 GFNFRFARYAI--GEVPSRDLYKVYGLRFVFIVSGTAGKFDFVPLLVTFGSGLGLLSLATIVADLLVTKCLRNAEFYYDR 396 Salpingoeca ro...
NP_945336     288 GYNFRFARYSSdaAGRTHRNLYKVYGFQLNVMVFGTASQFSIIHTIINVASVLTLMAVGSYICDVILLFMVKK----KYA 363 zebrafish
5SVL_A        356 KFEEVNE 362
CDS40794      378 RIDLVAQ 384 Echinococcus multilocularis
CDS42078      373 KFEVLTK 379 Echinococcus multilocularis
XP_001743535  394 KYQVVDE 400 Monosiga brevicollis MX1
EDO41363      376 KYQYVVE 382 starlet sea anemone
EFX89098      376 KYLLVDG 382 common water flea
XP_003384136  388 KYQKVAK 394 Amphimedon queenslandica
15_pfamImport 361 KSKRSKN 367
XP_004994999  397 KYEIVNE 403 Salpingoeca rosetta
NP_945336     364 KFESLIK 370 zebrafish
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